Farmatsevtichnii zhurnal最新文献

{"title":"Analysis of information providing for antihypertensive medicines according to the data of Ukrainian web services","authors":"Ryan Haight, діє Директива, Європейського парламенту, та Ради, ЄС про, звід законів, ЛЗ щодо, 200183ЕС, Директива, про дистанційну, торгівлю 977ЕC, та у кожній, країні є ло, кальні нормативні, акти, якими, встановлено вимоги, до відпуску, лише безрецептур","doi":"10.32352/0367-3057.3.23.05","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.05","url":null,"abstract":"The digitalization of the pharmaceutical field provides new opportunities to meet patient’s needs and to improve communications, which is important for pharmacies. According to the Law of Ukraine dated 17.09.2020 «On Amendments to Article 19 of the Law of Ukraine \"On Medicines\" regarding the implementation of electronic retail trade of medicinal products» and Article 81 of the Law of Ukraine «On Medicines» dated 28.07.2022), pharmacies were allowed to carry out electronic retail trade of pharmaceuticals on the condition that information about the right to online trade is entered in the Licensing Register for the manufacture of medicines \u0000The aim was the analysis and detailed study of the information content of sections of web services of pharmacies and web portals of Ukraine using the example of drugs for the treatment of arterial hypertension and substantiating the need for unification of information for patients. The basis of our analysis was information from 18 web services of pharmacy chains and 5 Internet portals for booking medicines. \u0000The analysis of the information support revealed that the most common filters for searching drugs for the treatment of arterial hypertension on resources were: medicine price scale, manufacturer, form of release and dosage. \u0000The results of the structural analysis of information showed that the following parameters are available on all sites and platforms: trade name of the medicinal product, price, form of release, dosage and quantity in the package. The information about the manufacturer is presented on 66% of pharmacy web services and 60% of web platforms. Only 28% of the pharmacy web services and 60% web platforms inform patients about the dispensing of prescription drugs. \u0000Identified differences in the information content of websites and web platforms require the unification of information for patients with arterial hypertension according to such parameters as: prescription leave; dispensing by e-prescription, with an emphasis on application features; the participation of pharmacies in social programs, especially reimbursement, which will contribute to the optimization of information and educational provision of patients for the rational use of drugs for chronic non-infectious diseases.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47412013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the tendencies and dynamics of electronic receipt prescribing for antibiotics and their electronic dispensing in Ukraine and Lviv region","authors":"О. Б. Блавацька, Г. Ю. Яцкова, Г. О. Сосновська","doi":"10.32352/0367-3057.3.23.06","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.06","url":null,"abstract":"Uncontrolled use of antibiotics (antibacterial, antimicrobial agents) leads to the growth of antibiotic resistance, which has become a global health problem. E-prescribing should increase the population's access to medical and pharmaceutical care. \u0000The purpose of the study: to establish the general trends of electronic prescribing of antibacterial drugs in Ukraine since its introduction in August 2022 and the impact of receipt e-prescribing on the controllability of antibiotic use, as well as to analyze the dynamics of the number of prescribed and dispensed electronic prescriptions for antibacterial drugs. \u0000We used the following research methods: informative, comparative and retrospective analysis of the dynamics of e-prescriptions for antibiotics. For this purpose, we used the e-data dashboards of the National Health Service of Ukraine (NHSU) and the data of the ENT KP «Pharmacy No.1» in Lviv for the period 08. 2022–05. 2023. \u0000In general, Lviv region is consistently in the top three, five or ten regions according to certain indicators. It was established that Lviv region is on the third place in Ukraine in terms of the number of issued e-prescriptions for antibiotics, on the first place in terms of the number of dispensed specified prescriptions, but in terms of the ratio of the number of issued e-prescriptions to those issued, Lviv region is in tenth place. The e-data of the National Health Service of Ukraine shows the nomenclature and number of electronic prescriptions of antibacterial drugs, the number of e-prescriptions that have been released, which are registered in the e-healthcare system. However, during the period of martial law, data on antibacterial drugs dispensed according to paper prescriptions or information certificates, equivalent to them, are not recorded. Thus, the e-data reflect the actual consumption of only those antibiotics that are recorded through the redemption of e-prescriptions, i.e. cover only one prescription segment. \u0000It is shown that although e-prescribing increases the control over the prescription of antibiotics, however, in force majeure circumstances of wartime, e-dispensing does not reflect the real picture of antibiotic consumption in general, but only one segment that is recorded in the e-system of health care. However, it is impractical to introduce an exclusively electronic prescription for antibiotics under martial law, as this carries the risk of limiting access to medical care. The use of the e-system allows to establish control over the quantitative indicators and assortment composition of antibiotics prescribed by doctors, which is definitely a necessary stage for improving the rational use of antibacterial drugs and combating antibiotic resistance.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47435232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical assessment of the rationale of the application of chemotherapy schemes containing immunotherapeutic drugs in the treatment of classical Hodgkin's lymphoma","authors":"М. Р. Матущак, Г. Л. Панфілова","doi":"10.32352/0367-3057.3.23.07","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.07","url":null,"abstract":"The use of new chemotherapy regimens for Hodgkin lymphoma, containing immunotherapeutic drugs, such as brentuximab vedotin, is an urgent direction in the development of modern oncohematology. The inclusion of these drugs in programs of financial support for hematological oncology patients by the state requires an assessment of the rationality of their use under the conditions of the current health care resource provision. \u0000The aim of the research is to carry out a pharmacoeconomic evaluation of the rationality of the use of brentuximab vedotin drugs in the treatment of classic Hodgkin lymphoma. \u0000Materials – the results of clinical studies of the effectiveness of two chemotherapy regimens for Hodgkin lymphoma (BrECAPP and BrECADD), which were published by German scientists in 2017 (Cochrane Central Register of Controlled Trials, CN-01443068), data from the domestic market of anticancer drugs and state procurement of medicines. General theoretical and applied (organizational and economic, marketing and pharmacoeconomic analysis, mathematical and statistical, etc.) research methods were applied. \u0000According to the results of the pharmacoeconomic evaluation of the rationality of the use of the BrECAPP and BrECADD schemes in the treatment of Hodgkin lymphoma, it was established that according to the indices of complete response after chemotherapy (%) the BrECADD scheme has clinical and economic advantages of application, and according to the index of complete remission as the final result of treatment (%), the situation is quite the opposite, that is, the BrECAPP scheme has advantages. The evaluation of the safety profile of the application makes it possible to assert the advantages of the application of the BrECADD scheme. Thus, taking into account the three indices under study (organ toxicity (%), manifestations of peripheral neuropathies (%) and the development of hematological side effects (%)), the indicated scheme had a clinical and economic advantage over the alternative scheme in two indices. This is organ toxicity (%), CEA2 = UAH 3,323.87/unit. ef. (%) against CEA1 = UAH 3,854.52/unit. ef. (%) according to the BrECAPP scheme and the development of hematological side effects (%) – CEA2 = UAH 29,008.32/unit. ef. (%) against CEA1 = UAH 29,084.14/unit. ef. (%) according to the BrECAPP scheme. \u0000In general, it can be stated that the BrECADD scheme is more rational and has economic advantages in the treatment of classical Hodgkin lymphoma compared to the BrECAPP regimen in terms of clinical efficacy and safety profile.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48993677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of physicians' preferences for optimizing the pharmacy assortment of glocose-lowering drugs","authors":"І. О. Власенко","doi":"10.32352/0367-3057.3.23.02","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.02","url":null,"abstract":"For the stable operation of the pharmacy and the proper support of patients with diabetes, it is necessary to optimize the assortment of glucose-lowering drugs (GLD), taking into account the significant prevalence of this disease. The demand for prescription drugs is formed by doctors who choose therapy and prescribe drugs. \u0000The purpose of this study was to determine the factors that influence of choosing GLD for the treatment of type 2 diabetes and the preferences of doctors when choosing GLD for therapy. \u0000They used a remote questionnaire form using Google forms. 732 doctor questionnaires were processed. Statistical processing was carried out using structural, comparative and graphic analysis. \u0000A survey of doctors established the factors that influence the prescription of drugs for the treatment of type 2 diabetes: high effectiveness and inclusion of drugs in treatment standards, their safety, and their own positive experience in prescribing drugs. It was also found that when choosing a GLD type, almost half of doctors take into account the patient's purchasing power and the presence of a GLD in the reimbursement program. The survey showed that a third of doctors prefer domestic GLD, and half of the respondents do so sometimes. When choosing foreign medical medications, doctors prefer German, French, and Swiss-made medical drugs. A significant part of doctors do not have preferences when choosing trade name (TN), but the majority of doctors who have preferences prefer TN mainly of foreign production and prolonged forms. It was found that about 10% of the responding doctors do not prescribe combined GLD. The majority of respondent doctors have preferences for combinations: metformin/glimepiride, dapagliflozin propanediol/metformin and sitagliptin/metformin. Problems have been identified at the stage of pharmacological supervision of GLD. Despite the fact that doctors noted in their practice the side effects of drugs in patients, only a fourth (22.7%) of respondents recorded these effects in accordance with the current legislation and made reports. \u0000It is advisable to use the results of the questionnaire to improve the care of patients with diabetes and to meet their needs by optimizing the pharmacy assortment. \u0000It is advisable to increase the list of International Nonproprietary Name of GLDs for reimbursement, which will contribute to the availability of modern treatment regimens, because the price of medicines limits the quality of modern treatment regimens for type 2 diabetes.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":"18 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69535047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modern approaches to the introduction of higher education degrees for the speciality 226 Pharmacy, industrial pharmacy","authors":"І. В. Бушуєва, Н. О. Ткaченкo, О. А. Кpемзеp, В. М. Oдинцoвa, Л. Г. Чеpкoвcькa","doi":"10.32352/0367-3057.3.23.08","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.08","url":null,"abstract":"The main direction of the development of the education system in Ukraine is the introduction of European standards, technologies, norms, and perspectives to ensure competitiveness in the market of European education services. \u0000The study aimed to highlight modern approaches to the standardization of higher education in the context of shaping professional competences of future pharmacists, to identify peculiarities and possibilities of applying a systemic approach to the development of a higher education standard for the specialty of 226 Pharmacy, Industrial Pharmacy of the second (master’s) level. \u0000The research materials consisted of references containing information on the development, approval, and implementation of higher education standard. The following methods were used in the study: synthetic, analytical, information search, descriptive, and generalization. \u0000The pharmaceutical industry is socially significant, and the specialty of 226 Pharmacy, Industrial Pharmacy, as well as all the specialties in the field of study 22 Health, are regulated. Therefore, professionals in this field should possess integrated knowledge and skills, be able to solve complex tasks and problems in the field of pharmacy and healthcare, both in practice and during the learning process. This involves conducting research, implementing innovations, and is characterized by uncertain conditions and requirements. A modern approach also involves the use of highly efficient technologies in the national and international educational and scientific environments, which ensure the preparation of competitive, highly qualified pharmaceutical professionals with moral and spiritual values, social responsibility, and community orientation. They are capable of providing quality pharmaceutical care to people and possess «soft skills». \u0000Upon the development of the approved higher education standard for the specialty of 226 Pharmacy, Industrial Pharmacy by the Ministry of Education and Science of Ukraine, the educational and professional programs Pharmacy and Perfume and Cosmetic Technologies were revised, and a list of competences as well as program learning outcomes for future pharmaceutical professionals was specified. These were aligned with the demands of the labor market and a professional-oriented approach, based on the concept of competences for a modern pharmacist and the variable components of educational and professional training programs","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45499632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of the condition and problems of providing diabetes patients with insulin preparations and means of glycemia monitoring","authors":"А. С. Немченко, Т. М. Коба, В. М. Назаркіна","doi":"10.32352/0367-3057.3.23.01","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.01","url":null,"abstract":"DM is a global medico-social problem, characterized by threatening trends in the spread and development of complications. One of the key elements of the system of effective treatment of DM is the continuous supply of patients with hypoglycemic preparations & means of means of glycemic control. Therefore, it is advisable to investigate approaches to ensuring the availability of MT for the prevention, diagnosis & treatment of DM in different countries. \u0000The purpose of the work is to analyze the condition & problems of providing patients with the necessary pharmaceuticals & diagnostic products to achieve the appropriate level of compensation for diabetes. \u0000The research used: analysis of documents, marketing analysis, comparison, generalization, mathematical and statistical methods, graphic method. \u0000The analysis of official statistics shows a constant increase in the incidence of diabetes in the world among the population of different ages. Analysis of international experience shows significant differences in approaches to the organization of care for patients with diabetes, in particular, reimbursement of the cost of insulin therapy & glycemic control. In low- and middle-income countries, due to insufficient financing of antidiabetic measures, higher rates of mortality & disability related to complications of DM are recorded. In Ukraine, a government program for the reimbursement of sugar-lowering drugs has been introduced to increase the availability of drugs. Reimbursement is subject to 45 insulin preparations for 12 INNs (of which 18 are without copayment). According to the NHS, 226,200 patients receive insulin under PMG (since 2019, 2.27 mln prescriptions have been paid). The analysis of prescriptions shows that insulin analogues of foreign production are most often used. Based on the results of the research on the availability of modern MTs for the diagnosis and treatment of diabetes, it can be concluded that a wide range of glycemic control tools, including Continuous Monitoring Systems, are available on the domestic market. Providing patients with means of glycemic control is carried out at the expense of regional programs. \u0000The problem of providing patients with DM with the necessary medicines & medical devices requires a complex solution & coordination of central & local authorities actions. The priority direction of improving the efficiency and accessibility of medical care for patients with DM is to carry out proper OMT diagnosis & treatment of DM in order to include them in the reimbursement lists & procurement nomenclature.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45898052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Problems and prospects of medical provision for military personnel with COVID-19 in the conditions of medical insurance","authors":"В. В. Трохимчук, І. О. Панкратов","doi":"10.32352/0367-3057.3.23.03","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.03","url":null,"abstract":"To date, the treatment of patients with COVID-19, which caused an unprecedented pandemic in 2019–2023, remains difficult. Military personnel of the Armed Forces of Ukraine during conscription, when returning from business trips and vacations (especially those who are in the incubation period or are asymptomatic) can bring COVID-19 into the unit and cause an outbreak of the disease. \u0000The purpose of the work was to conduct an analysis of the existing models of the functioning of insurance medicine in some countries in the world and in Ukraine for their further possible application in the system of medical support of the Armed Forces; factors and conditions affecting the course of the disease on COVID-19 were additionally studied. \u0000The main preventive measures against the spread of COVID-19 among military personnel are compliance with sanitary standards, control of disease symptoms and timely vaccination or revaccination. In the treatment of patients with COVID-19, depending on the conditions of stay and the severity of the disease, the following groups of drugs are used: analgesics and antipyretics, rehydration, antiviral, antibacterial and antifungal, low molecular weight heparins, systemic corticosteroids and vitamins, which military personnel receive free of charge. The creation of an effective system of insurance medicine in Ukraine should provide for the possibility for servicemen of the Armed Forces of Ukraine to receive medical care in any health care facility, regardless of departmental subordination, by creating an electronic medical card of a serviceman, which will be included in the electronic health care system of Ukraine. \u0000The conducted studies make it possible to draw a conclusion about the need for improvement and further development of the scientific and practical foundations of systematic research in the military medical service of the Armed Forces of Ukraine, improving the quality and efficiency of medical support for servicemen, introducing modern approaches and methods of making sound management decisions on issues of protection and prevention of proliferation COVID-19.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45167808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of the morbidity of breast cancer in Ukraine and the city of Kyiv","authors":"Я. Д. Рафальська, К. Л. Косяченко","doi":"10.32352/0367-3057.3.23.04","DOIUrl":"https://doi.org/10.32352/0367-3057.3.23.04","url":null,"abstract":"One of the main causes of mortality worldwide is malignant neoplasms, and in Ukraine, breast cancer ranks first among all cancer diseases and mortality among women. With the help of official epidemiological data, it is possible to estimate the level and forecast the costs of the prevention and treatment of breast cancer in women. \u0000The purpose of the study was to analyze epidemiological indicators of breast cancer incidence and mortality among the female population in Ukraine and the city of Kyiv. \u0000The study used data on the incidence and mortality from breast cancer in women of the National Cancer Registry of Ukraine for 2011–2021. Analytical-comparative, epidemiological, graphic, and mathematical-statistical methods were used. \u0000The results of the analysis of epidemiological indicators showed that the largest number of sick women was registered in 2012 – 17,746, and the smallest in 2020 – 12,736. The highest growth rate of the chain coefficient of decrease/increase in the incidence and mortality rate of breast cancer in women was in 2015 – 23% and 8%, respectively. The lowest number of registered cases of breast cancer for 2016–2020 in Ukraine is observed in the Western region, and the largest in the Northern region. The highest mortality rate was recorded in women in the city of Kyiv and in Ukraine as a whole from breast cancer in 2012 (18.2 and 16.9 per 100,000 population, respectively). In general, the mortality trend in the city of Kyiv is higher than in Ukraine. The results of the analysis showed that breast cancer is most often detected for the first time at the I–II stage of the disease. The largest number of such patients was found in Ukraine in 2015 – 78.6% of the total number of cases. \u0000Taking into account the analyzed epidemiological data on the incidence and mortality of women from breast cancer in Ukraine and the city of Kyiv, it is necessary to conduct social programs for early screening of breast cancer at the state level and provide such patients with effective anticancer drugs at all stages of treatment.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43816987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and research of ointment with essential oil of thyme for the treatment of the scalp and hair parts of the head","authors":"Л. О. Пучкан, О. О. Салій, Л. А. Фуклева, М. М. Малецький","doi":"10.32352/0367-3057.2.23.04","DOIUrl":"https://doi.org/10.32352/0367-3057.2.23.04","url":null,"abstract":"Dermatological diseases are the most widespread in the whole world. According to WHO, 20–30% of the world's population suffers from fungal skin diseases and 25–35% from pustular diseases. Pustular diseases (pyoderma) are the result of pathogenic staphylococci and streptococci, and fungal diseases (dermatomycoses) are caused by various types of fungi. Today, these diseases are treated with various types of drugs, but the active ingredient in almost all of them is synthetic compounds (antibiotics, sulfonamides, imidazole derivatives, etc.). Medicines of natural origin are scarce. In order to increase the number of phytoremedies for external use (ointments), which have medicinal plant active components, a study was conducted using standardized essential oil of common thyme. \u0000The aim of the work was to study the effect of excipients on the ointment base by the method of mathematical planning of the experiment for the development of the optimal composition of the dermatological ointment with the essential oil of common thyme. \u0000Excipiennts for ointment bases of hydrophobic and emulsion composition were used to develop the optimal composition of the ointment. The concentration of thyme essential oil was 5% in all samples. The degree of thymol release in an in vitro study using the equilibrium dialysis method was chosen as the criterion for choosing the optimal composition. Excipiennts allowed in pharmacy, with known characteristics, safety profile, and application experience were used as auxiliary substances. Using Duncan's multiple criterion, a number of advantages were created: а7 > а8 > а9 > а10 > а6 >а2 > а5 > а3 > а1 > а4. \u0000On the basis of the conducted studies, the optimal composition of the ointment was chosen for the treatment of lesions of the scalp and hair. The studied organoleptic and technological properties and quality indicators (homogeneity, colloidal stability, thermal stability, microbiological purity) of ointment with thyme essential oil during long-term storage at a temperature of +2–+8 °C established the stability of the developed composition of the ointment during two years of observation. The creation of a new local remedy for the treatment of lesions of the scalp and its hair part will allow to expand the arsenal of safe and effective remedies.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41516443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of preferences of patients with diabetes regard to pharmaceutical services","authors":"І. О. Власенко","doi":"10.32352/0367-3057.2.23.01","DOIUrl":"https://doi.org/10.32352/0367-3057.2.23.01","url":null,"abstract":"Pharmacies are a component of the healthcare. Pharmaceutical care and pharmaceutical services improve disease control, quality of patients life and reduce of the burden on healthcare. The implementation of pharmaceutical care and pharmaceutical services for patients with diabetes according to the standards of the GPP is relevant for the domestic pharmacy. Therefore, it is advisable to determine the preferences of patients with diabetes because they have their own needs for treatment and control. \u0000The purpose of the study was to study the views of patients with diabetes regarding to function of pharmacies, pharmaceutical services and determine their preferences. \u0000The survey of patients with diabetes by the questionnaire method was carried out. Relevant questionnaires of 510 patients with type 1 and type 2 diabetes were included in the study. \u0000The results of the survey showed that the majority of patients with diabetes would like to be served in a specialized pharmacy that specializes in drugs and medical products for diabetes. On the basis of the study, the preferences of patients with diabetes regarding to the activities of pharmacies were determined: availability of a wide rang of product; loyalty program for special products related to diabetes, additional services and pharmaceutical consultations. The majority of those interviewed noted that they need a pharmacist's consultation on taking medications. This type of service requires training of pharmacists in diabetes in order to provide pharmaceutical care at an appropriate level. Pharmaceutical services which patients with diabetes need were identificated. There are: testing of blood glucose, cholesterol, blood pressure, weight check, calculation of body mass index and interpretation of results. The creation of a «diabetes self-management school» based on pharmacies will improve the availability of education for patients with diabetes. It is necessary to study the demand directly in the area of the pharmacy before introduction this type of service. It is important to implement systematic special events in pharmacies for the World Diabetes Day. Thes is appropriated for the general population, but also for patients with diabetes. From the point of view of patients with diabetes during this event, they are interested in: consultation of an endocrinologist and nutritionist; blood glucose test; test of diabetes risk; information materials about diabetes. \u0000The results of the survey can be prospectively used to improve the service of patients with diabetes and provide for their needs.","PeriodicalId":32942,"journal":{"name":"Farmatsevtichnii zhurnal","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48258723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}