Jurnal Penyakit Dalam Indonesia最新文献

{"title":"Update Pemeriksaan Laboratorium Infeksi Saluran Kemih","authors":"Weny Rinawati, Dian Aulia","doi":"10.7454/jpdi.v9i2.319","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.319","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44540586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atherogenic Index of Plasma Berkorelasi dengan Prolonged Length of Stay pada Pasien COVID-19 dengan Diabetes Melitus Tipe 2 di RSUP Sanglah Denpasar","authors":"I. G. A. Sastrawan, Putu SAtherogenic Index Of Plasma iatyakumara Upadhana, Putu Novi Sri Handayani, Tika Rizki Nur Laela, Kadek Aprilia Sukma Dewi, I. Wiguna, Komang Andjani Putri, Komang Adya Data Agrasidi, Cindy Gracia Trisina, Putu Sudarmika, I. M. Semadi, I. K. A. Somia","doi":"10.7454/jpdi.v9i2.784","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.784","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47363729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Korelasi MIR-146A dan Platelet to Lymphocyte Ratio terhadap Fibrosis Hati pada Hepatitis B","authors":"Brilliant Van Fitof, R. S. Budi S, T. Y. Pramana","doi":"10.7454/jpdi.v9i2.750","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.750","url":null,"abstract":"Platelet to lymphocyte ratio (PLR) hepatitis B. Metode metode cross ABSTRACT Introduction . Liver fibrosis is a pathological condition as a recovery tissue respond, characterized by excessive extracellular matrix deposit. MicroRNA (miRNA or miR) has a pivotal role on progression of hepatic cirrhosis. Platelet to lymphocyte ratio (PLR) could be as a good predictor of liver fibrosis. This study aimed to find the correlation between miR-146a and PLR with liver fibrosis in Hepatitis B. Method . The cross sectional study conducted in Gastroenterohepatology Clinic of Internal Medicine Department RSUD Dr. Moewardi Surakarta in Januari – Juli 2020, involving 26 Hepatitis B naïve patients. Complete blood count, serum creatinine, liver enzyme, HBsAg, miR-146a, elastography measurement using FibroScan were performed. Results . The average age of patients was 49 (SD 11) years, mainly men (n : 17, 66%). The results from bivariate analysis demonstrated that miR-146a was significantly associated with liver fibrosis (r = 0,639 dan p < 0,001). PLR was also significantly associated with liver fibrosis (r = -0,455 dan p = 0,020). Conclusion . There was a significant correlation between miR-146a and PLR with liver fibrosis on Hepatitis B.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45371230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hubungan antara Diabetes Melitus Tipe 2 terhadap Luaran Pasien COVID-19 di Rumah Sakit Sanglah pada Tahun 2020-2022","authors":"Putu Satyakumara Upadhana, I. G. A. Sastrawan, I. G. A. G. D. Rahmautami, Merry Merry, Ni Putu Kostarika Melia Daradila, Derian Adiguna Sutanto, Ida Ayu Chandranita Manuaba, Putu Ardy Hartadi, Komang Vika Nariswari Ratna Kinasih, Putu Sudarmika, I. M. Semadi, I. K. A. Somia","doi":"10.7454/jpdi.v9i2.774","DOIUrl":"https://doi.org/10.7454/jpdi.v9i2.774","url":null,"abstract":"Introduction. People with type 2 diabetes mellitus (T2DM) are at a higher risk of mortality from COVID-19. This study aimed to identify the relationship between T2DM and the outcome of COVID-19 patients in Sanglah Hospital Denpasar, Bali. Methods. An observational analytic study with a cross-sectional approach was conducted among COVID-19 patients. We used secondary data from the records of confirmed COVID-19 patients who were treated at Sanglah Hospital on 1 August 2020 – 28 February 2022. Sample were selected with total sampling technique. Results. There were 1,056 patients involved in this study. Most of the patients were male (n=571; 54.1%), with a median age of 59 years old. Most of the patients were categorized as severe COVID-19 (n=641; 60.7%). A total of 275 patients had T2DM (26.0%). Chi-square analysis showed a significant association of T2DM with mortality (PR=1.422; 95%CI=1.162-1.742; p=0.001), severe COVID-19 (PR=1.726; 95%CI=1.365-2.184; p<0.001), ventilator usage (PR=1.334; 95%CI=1.093-1.791; p=0.045), Conclusion. There is a significant association between T2DM with mortality risk, severe COVID-19, and longer hospitalization duration in COVID-19 patients.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45971212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dampak Penyakit Ginjal terhadap Pasien COVID-19 di Rumah Sakit Sanglah Denpasar, Bali, Indonesia pada Tahun 2021","authors":"Putu Satyakumara Upadhana, I. G. A. Sastrawan, I. Cahyarini, A. Umam, Amanda Dwi Putri, I. G. R. Adhyatma, I. K. A. Somia","doi":"10.7454/jpdi.v9i1.658","DOIUrl":"https://doi.org/10.7454/jpdi.v9i1.658","url":null,"abstract":"Pendahuluan. Selain berdampak pada sistem pernapasan, COVID-19 juga berdampak pada organ lain yaitu ginjal. Respons inflamasi sistemik memiliki peranan dalam perburukan klinis pada pasien COVID-19 dengan penyakit ginjal. Penelitian ini bertujuan untuk mengetahui dampak penyakit ginjal terhadap pasien COVID-19. Metode. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross-sectional. Data yang digunakan adalah data sekunder dari rekam medis pasien terkonfirmasi COVID-19 yang dirawat di RSUP Sanglah mulai tanggal 1 Mei 2021 sampai dengan 31 Agustus 2021 dengan menggunakan teknik total sampling.Hasil. Terdapat 248 pasien yang dilibatkan dalam penelitian ini. Mayoritas pasien adalah laki-laki (52,4%) dengan rerata usia keseluruhan pasien adalah 59 (rentang 20-92) tahun. Sebagian besar pasien adalah COVID-19 dengan derajat berat (65,3%). Sebanyak 77 pasien menderita penyakit ginjal (31,0%) dan penyakit ginjal yang paling banyak ditemukan adalah acute on chronic kidney disease (n=33; 42,8%). Terdapat perbedaan bermakna pada kadar hemoglobin (p<0,001), nitrogen urea darah (BUN) (p<0,001), kreatinin serum (p<0,001), dan prokalsitonin (p<0,001) pada pasien yang diklasifikasikan berdasarkan penyakit ginjal. Analisis chi-square menunjukkan bahwa pasien COVID-19 dengan penyakit ginjal berhubungan terhadap sepsis [PR=2,587 (IK 95% 1,750-3,824); p<0,001)], mortalitas [PR=1,696 (IK 95% 1,114-2,583); p=0,018)], dan COVID-19 derajat berat [PR=1,513 (IK 95% 1,077-2,342); p=0,040)]. Analisis regresi logistik menunjukkan pasien COVID-19 dengan penyakit ginjal berhubungan secara signifikan terhadap sepsis [PR=4,318 (IK 95% 1,767-10,553); p<0,001)] dan mortalitas [PR=1,413 (IK 95%= ,664-3,005); p=0,045)]. Kesimpulan. Penyakit ginjal berhubungan secara signifikan dan meningkatkan risiko terhadap kejadian sepsis dan mortalitas pada pasien COVID-19. Kata Kunci: COVID-19, komorbiditas, penyakit ginjalKidney Disease and Its Impact on COVID-19 Patients at Sanglah Hospital Denpasar, Bali, Indonesia in 2021Introduction. Besides having an impact on the respiratory system, COVID-19 also has an impact on other organ such as the kidneys. The systemic inflammatory response thought to be associated with bad prognosis of COVID-19 patients with kidney disease. This study aimed to determine the impact of kidney disease on COVID-19 patients. Methods. This study is an observational analytic study with a cross-sectional approach. The data used is secondary data from the records of confirmed COVID-19 patients who were treated at Sanglah Hospital from 1 May 2021 to 31 August 2021 using total sampling technique.Results. There were 248 patients included in this study. The majority of patients were male (52.4%) with the median overall age of the patients was 59 (range 20–92) years. Most of the patients were severe COVID-19 (65.3%). A total of 77 patients had kidney disease (31.0%) which the most common kidney disease found in patients was acute on chronic kidney di","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49310310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mutasi dan Varian Coronavirus Disease 2019 (COVID-19): Tinjauan Literatur Terkini","authors":"Adi Susilo, C. Jasirwan, Syahidatul Wafa, Suzy Maria, W. Rajabto, A. Muradi, Ihza Fachriza, Myranda Zahrah Putri, Stacy Gabriella","doi":"10.7454/jpdi.v9i1.648","DOIUrl":"https://doi.org/10.7454/jpdi.v9i1.648","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43159779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Model Prediksi Kejadian Pneumonia 30 Hari Pasca Bedah Abdomen pada Pasien Usia Lanjut","authors":"Noto Dwimartutie, Harini Oktadiana, Gurmeet Singh, Wifanto Saditya Jeo, kun Harimurti","doi":"10.7454/jpdi.v9i1.716","DOIUrl":"https://doi.org/10.7454/jpdi.v9i1.716","url":null,"abstract":"Introduction. Physiologic changes in respiratory tract in elderly increase incidence of post-operative pneumonia. Postoperative pneumonia in non-thoracic surgery was found higher in abdominal surgery. This study aimed to develop a prediction model of 30-day post-operative pneumonia in elderly patients undergoing abdominal surgery. Methods . A retrospective cohort study was conducted using elderly patient’s medical records who underwent abdominal surgery in Cipto Mangunkusumo General Hospital. Multivariate analysis using logistic regression was used to determine Odds Ratio (OR). Model’s calibration performance was determined by Hosmer-Lameshow test and its discrimination performance was determined by calculating area under the curve (AUC). Results . Of 753 subject who underwent abdominal surgery, postoperative pneumonia was found in 9.2% subjects. Independent predictors for 30-day postoperative pneumonia were functional status [ADL Barthel 0-11, odds ratio (OR) 6.908 (95% confidence interval (CI) 2.933-16.273); ADL Barthel 12-19, OR 3.191 (95%CI 1.53-6.657)], upper abdominal surgery [OR 4.869 (95%CI 1.805-13.132)], chronic obstructive pulmonary disease [OR 6.888 (95%CI 2.001-23.709)], and albumin level <3 g/dl [OR 2.54 (95%CI 1.404-4.596)]. Prediction model of pneumonia was stratified into lower risk (score <2; probability 3.4%), moderate risk (score 2-3; probability 19.97%), and high risk (score >3; probabililty 60.42%). Hosmer-Lemeshow test revealed p-value 0.452 and the AUC value is 0.811 (95%CI 0.87-0.97). of 30-day post-operative pneumonia for elderly patients undergoing abdominal surgery consisted of 4 predictors (functional status, upper abdominal surgery, COPD and albumin level <3 g/dl) has a good performance.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41373804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manajemen Nyeri pada Karsinoma Hepatoseluler Stadium Lanjut: Sebuah Studi Kasus","authors":"Fita Fitrianti, Hamzah Shatri, Edward Faisal, Rudi Putranto, Ratih Arianita Agung, Leonard Nainggolan, Kemal Fariz Kalista, Cophiadi Irawan","doi":"10.7454/jpdi.v9i1.509","DOIUrl":"https://doi.org/10.7454/jpdi.v9i1.509","url":null,"abstract":"Hepatocelullar carcinoma (HCC), the most common primary liver malignancy is the fifth most common cancer and the third most frequent cause of cancer related death globally. Pain comprises one the most common symptoms of HCC and may have severely negative effects on patient’s quality life. Furthermore, patients with HCC often presented with a cirrochis,so to control pain in this patient poses a clinical challenge. This case report discuss about a young 26-years-old male patient who presented with a four-month history of right upper quadrant abdominal pain and weight loss. HbsAg positive and serum alpha-fetoprotein level was high. Computed tomography (CT) and liver biopsy confirmed the presence of primary hepatocellular carcinoma.,with lung metastatic from the radiologic x-ray. Patient came with a loss of consciousness due to hypoglicemia. During hospitalization, patient complaint of abdominal pain and was given morphine intermediate release (MIR) to control the pain. By administering measurable and well-controlled opioids, the patient’s suffering can be reduced, thus improving the patient’s quality of life.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45575828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID-19 dari Perspektif Penyakit Ginjal : Dalam Rangka Memperingati Hari Ginjal Sedunia (World Kidney Day 2022)","authors":"A. I. Khumaedi","doi":"10.7454/jpdi.v9i1.754","DOIUrl":"https://doi.org/10.7454/jpdi.v9i1.754","url":null,"abstract":"Secara global, hingga saat ini pandemi Coronavirusdisease-19 (COVID-19) telah menjangkit lebih dari 450juta orang di dunia dan menyumbang kematian sebanyak6 juta jiwa. Situasi di Indonesia menunjukkan bahwa 5,9juta jiwa terkonfirmasi positif COVID-19, dengan kasusmeninggal mencapai 150 ribu jiwa. Case fatality rate(CFR) secara keseluruhan menunjukkan angka 2,6%,namun angka ini bervariasi sepanjang tahun dan pernahdilaporkan sebanyak 9,6% pada Juni 2020 di DKI Jakarta.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49656918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Karakteristik Pasien Efusi Pleura Non-Maligna di RSUD Dr. Zainoel Abidin Tahun 2019","authors":"Teuku Romi Imansyah Putra, Price Maya, Maryatun Hasan, Agung Pranata, Safira Salsabila, Hesti Anandini Sariningrum","doi":"10.7454/jpdi.v9i1.696","DOIUrl":"https://doi.org/10.7454/jpdi.v9i1.696","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44377247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}