高龄患者30个腹部手术日的肺炎预测模型

Noto Dwimartutie, Harini Oktadiana, Gurmeet Singh, Wifanto Saditya Jeo, kun Harimurti
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引用次数: 0

摘要

介绍。老年人呼吸道的生理变化增加了术后肺炎的发病率。非胸外科术后肺炎发生率高于腹部外科。本研究旨在建立老年腹部手术患者术后30天肺炎的预测模型。方法。采用回顾性队列研究方法,对在Cipto Mangunkusumo总医院接受腹部手术的老年患者病历进行分析。采用logistic回归的多因素分析确定优势比(OR)。模型的标定性能由Hosmer-Lameshow检验确定,识别性能由曲线下面积(AUC)计算确定。结果。在753例接受腹部手术的患者中,9.2%的患者发现术后肺炎。术后30天肺炎的独立预测因子为功能状态[ADL Barthel 0-11,优势比(OR) 6.908(95%可信区间(CI) 2.933-16.273);ADL Barthel 12-19, OR 3.191 (95%CI 1.53-6.657)],上腹部手术[OR 4.869 (95%CI 1.805-13.132)],慢性阻塞性肺疾病[OR 6.888 (95%CI 2.001-23.709)],白蛋白水平3;probabililty 60.42%)。Hosmer-Lemeshow检验显示p值0.452,AUC值0.811 (95%CI 0.87 ~ 0.97)。功能状态、上腹部手术、COPD、白蛋白水平< 3g /dl 4个预测指标对老年腹部手术患者术后30天肺炎的预测效果较好。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Model Prediksi Kejadian Pneumonia 30 Hari Pasca Bedah Abdomen pada Pasien Usia Lanjut
Introduction. Physiologic changes in respiratory tract in elderly increase incidence of post-operative pneumonia. Postoperative pneumonia in non-thoracic surgery was found higher in abdominal surgery. This study aimed to develop a prediction model of 30-day post-operative pneumonia in elderly patients undergoing abdominal surgery. Methods . A retrospective cohort study was conducted using elderly patient’s medical records who underwent abdominal surgery in Cipto Mangunkusumo General Hospital. Multivariate analysis using logistic regression was used to determine Odds Ratio (OR). Model’s calibration performance was determined by Hosmer-Lameshow test and its discrimination performance was determined by calculating area under the curve (AUC). Results . Of 753 subject who underwent abdominal surgery, postoperative pneumonia was found in 9.2% subjects. Independent predictors for 30-day postoperative pneumonia were functional status [ADL Barthel 0-11, odds ratio (OR) 6.908 (95% confidence interval (CI) 2.933-16.273); ADL Barthel 12-19, OR 3.191 (95%CI 1.53-6.657)], upper abdominal surgery [OR 4.869 (95%CI 1.805-13.132)], chronic obstructive pulmonary disease [OR 6.888 (95%CI 2.001-23.709)], and albumin level <3 g/dl [OR 2.54 (95%CI 1.404-4.596)]. Prediction model of pneumonia was stratified into lower risk (score <2; probability 3.4%), moderate risk (score 2-3; probability 19.97%), and high risk (score >3; probabililty 60.42%). Hosmer-Lemeshow test revealed p-value 0.452 and the AUC value is 0.811 (95%CI 0.87-0.97). of 30-day post-operative pneumonia for elderly patients undergoing abdominal surgery consisted of 4 predictors (functional status, upper abdominal surgery, COPD and albumin level <3 g/dl) has a good performance.
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