Jurnal Penyakit Dalam Indonesia最新文献

{"title":"Performa Diagnostik Global Leadership Initiative on Malnutrition (GLIM) dibandingkan dengan Malnutrition Nutritional Assessment (MNA) dalam Pengkajian Malnutrisi pada Pasien Geriatri di Rawat Inap","authors":"","doi":"10.7454/jpdi.v10i1.1104","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1104","url":null,"abstract":"Introduction. As many as 76.6% of patients aged 60 years and above (elderly) are malnourished or at risk of malnutrition based on MNA within the first 48 hours of hospital admission. The prevalence of malnutrition varies widely depending on the population studied, the healthcare setting and the tools used for the assessment. To date, SGA is widely used in the diagnosis of malnutrition for adults and MNA for elderly patients. Recently, experts proposed empirical consensus of GLIM criteria for determining the diagnosis of malnutrition in adults. This study aimed to investigate the diagnostic performance of GLIM criteria as a new consensus in determining the diagnosis of malnutrition in comparison to MNA as a semi-gold standard for nutritional assessment in the elderly. Methods. A cross-sectional study was conducted from January to April 2022 on 103 consecutively recruited elderly patients aged ≥60 years in the Internal Medicine Wards at Dr. Cipto Mangunkusumo Hospital (RSCM), Jakarta, Indonesia. Results. There were 91.3%, 57.3% and 54.4% malnourished elderly patients upon admission to the hospital, based on GLIM criteria, MNA-SF and MNA-LF, respectively. GLIM has good accuracy compared to both MNA-SF and MNA-LF, as long as the category of malnourished in MNA is a combination of malnutrition and at risk of malnutrition. GLIM had 97.9% sensitivity, 87.5% specificity, AUC 0.93, 98.9% PPV, 77.8% NPV, 7.83 positive LR and 0.02 negative LR towards MNA-SF, and a sensitivity value of 98.9%, specificity 88.9%, AUC 0.94, PPV 98.9%, NPV 88.9%, positive LR 8.91, and negative LR 0.01 towards MNA-LF. Conclusion. GLIM showed good diagnostic accuracy to determine nutritional status in the elderly, especially upon admission to the hospital, so that appropriate early nutritional interventions can be given.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48595777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sensitisasi Alergen Makanan pada Pasien Kolitis Eosinofilik: Laporan Kasus","authors":"Agnes Dina Irene Dorithy Zagoto, Deshinta Putri Mulya, Neneng Ratnasari","doi":"10.7454/jpdi.v10i1.1425","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1425","url":null,"abstract":"Eosinophilic colitis is a very rare disease that can occur in the bimodal population (neonates and young adults) with a prevalence was 2.1/100,000 in overall population and 2.3/100,000 in adults. However, only about 0.1% of cases were diagnosed from biopsy results obtained during colonoscopy. The lack of precise histological criteria for the quantity of eosinophils in the colon mucosa creates a distinct challenge in diagnosing eosinophilic colitis. Eosinophilia in the gastrointestinal tract can be mediated by IgE and non-IgE, but non-IgE tends to be dominant in adults. This report discusses about a case of a 64-year-old male with bloody diarrhea that has been occur for two years. The anamnesis revealed symptoms suggestive of eosinophilic colitis, including complaints of diarrhea with abdominal pain and weight loss. Laboratory tests revealed an increase in peripheral eosinophil count and elevated levels of IgE. A positive skin prick test supported the presence of food allergen sensitization. The endoscopy revealed signs of ulcerative colitis, but the biopsy showed evidence of eosinophilic colitis. Initially, the patient was treated for ulcerative colitis but did not show improvement. Following treatment for eosinophilic colitis, the patient’s clinical status showed improvement. Since eosinophilic colitis can be chronic and recur, an accurate diagnosis and proper management are crucial for achieving complete remission.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46328331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaksin Influenza sebagai Modalitas Pencegahan Kejadian Rawat Inap Akibat Penyakit Kardiovaskular","authors":"","doi":"10.7454/jpdi.v10i1.1424","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1424","url":null,"abstract":"Penyakit kardiovaskular merupakan salah satu penyakit terbanyak penyebab perawatan pasien di rumah sakit. Pada pasien dengan penyakit kardiovaskular, infeksi virus seperti influenza dapat menjadi pencetus terjadinya sindrom koroner akut dan gagal jantung akut. Beberapa studi menunjukkan keterkaitan kuat antara infeksi influenza dan kejadian kardiovaskular","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43836112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gambaran Risiko Post-Traumatic Stress Disorder (PTSD) pada Penyintas COVID-19 di Rumah Sakit Universitas Andalas","authors":"","doi":"10.7454/jpdi.v10i1.1032","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1032","url":null,"abstract":"Introduction. The COVID-19 pandemic has a negative impact on life where sufferers can experience emotional problems such as despair, deep sadness, helplessness, anxiety, and depressive symptoms. Especially in hospitalized COVID-19 survivors, there are sequelae in the form of anxiety, depression, and Post-traumatic Stress Disorder (PTSD). PTSD experienced by COVID-19 survivors will affect the patient’s quality of life in the future. This study aimed to assess the risk of PTSD in COVID-19 survivors who had been hospitalized at Andalas University Hospital. Methods. A cross-sectional descriptive study was conducted among COVID-19 survivors aged ≥15 years who had been hospitalized at Andalas University Hospital. Samples were selected by using total sampling method with inclusion criteria included experiencing mild, severe, or critical clinical symptoms during COVID-19 infection, being discharged from Andalas University Hospital for six months or more, and willing to participate in the study by signing an informed consent. Samples who have met the inclusion criteria completed the Bahasa Indonesia version of PCL-5 (PTSD Checklist for DSM-5) questionnaire which has been tested for its validity and reliability. Respondents were categorized as having PTSD risk if the questionnaire results showed a score of ≥23. The collected data were subsequently analyzed using univariate analysis. Results. A total of 75 respondents were included in the study, of which 9.3% (7) were found to be potentially or at risk of PTSD. The group of respondents who were at risk of PTSD was mostly comprised of females, and all of them experienced the four PTSD symptoms (intrusion/re-experiencing, avoidance, negative alterations in cognition and mood, and hyperarousal). The most common trigger that causes PTSD among respondents was the experience of a previous life-threatening traumatic event (71.43%). In addition, the most frequent clinical symptoms of COVID-19 in the PTSD risk group were severe clinical symptoms (71.43%). Conclusions. COVID-19 survivors who have the potential to experience PTSD are predominantly female survivors with severe clinical symptoms, experiencing all four PTSD symptoms, and having a traumatic life-threatening experience during COVID-19 hospitalization.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42829396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaksinasi Influenza sebagai Prediktor Terjadinya Kejadian Rawat Inap Akibat Kejadian Kardiovaskular pada Pasien dengan Riwayat Penyakit Jantung Koroner: Suatu Laporan Kasus Berbasis Bukti","authors":"","doi":"10.7454/jpdi.v10i1.1357","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1357","url":null,"abstract":"Influenza is known to worsen cardiovascular events in patients with a history of coronary heart disease. However, the effectiveness of influenza vaccination in reducing hospitalization due to cardiovascular disease is not clearly known. We aim to determine the effect of influenza vaccination on hospitalization rates due to cardiovascular disease in patients with a history of coronary heart disease. Relevant literature was searched on four electronic databases: MEDLINE, EMBASE, SCOPUS, and Cochrane Library, using predetermined keywords. Critical review of the studies was done using the Center of Evidence Based Medicine (CEBM) University of Oxford assessment tool. The search yielded six articles, and critical review was done based on validity, importance, and applicability. Three studies showed that influenza vaccination in patients with coronary heart disease would reduce hospitalization rates due to cardiovascular disease within 12 months after vaccination. Three studies did not show any effect of influenza vaccination on hospitalization rates due to cardiovascular disease. The samples in the three studies that found a protective effect of the influenza vaccine were older and at higher risk of experiencing cardiovascular events. Based on our review, we conclude that influenza vaccination can be given to prevent hospitalization due to cardiovascular disease in patients with a history of coronary heart disease, especially in high-risk patients.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48140526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Profilaksis Pasca Paparan Virus HIV pada Petugas Kesehatan","authors":"T. Karjadi","doi":"10.7454/jpdi.v10i1.1418","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1418","url":null,"abstract":"Health workers (HCWs) are prone to get infected by HIV infection when carrying out their duties. The injuries can be caused by needle sticks, sharp objects (scalpels, lancets, or other) that have been exposed to body fluids or splashes of body fluids onto the body’s mucosa (eyes, nose, mouth) and non-intact skin have the potential to transmit the HIV infection. Post-exposure transmission due to contamination of body fluids to health workers can be prevented by providing post-exposure prophylaxis therapy. Post-exposure prophylaxis (PEP) is given as soon as possible and no later than 72 hours after exposure. Prophylaxis is given to HCWs who are significantly exposed using three antiretroviral drugs. In Indonesia, for adolescents and adults ≥ 10 years old, the main choice is Tenofovir (TDF) + Lamivudine (3TC) + Dolutegravir (DTG). Simultaneously with the administration of ARV drugs, counseling is also carried out regarding side effects of ARV, medication adherence, drug interactions, the possibility of seroconversion, and if necessary, management of anxiety that may arise. ARVs will be given for 28 days. After being given post-exposure prophylactic therapy, monitoring for side effects of ARV drugs must be carried out which are given in the 2nd and 4th week. Re-examination of HIV testing to see the effectiveness of treatment was carried out at 12 weeks and 6 months after exposure.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47399214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modulasi Mikrobiota untuk Memperbaiki Laju Filtrasi Glomerulus, Toksin Uremik, dan Penanda Inflamasi pada Gagal Ginjal Kronik: Telaah Sistematik dan Meta-Analisis","authors":"Burhan Gunawan, R. Purwata, S. Hidayat, Roy Akur Pandapotan, Jennifer Jennifer","doi":"10.7454/jpdi.v10i1.1036","DOIUrl":"https://doi.org/10.7454/jpdi.v10i1.1036","url":null,"abstract":"Introduction. Dysbiosis microbiota is considered as one of the consequences and impacts of high uremic toxins in patients with Chronic Kidney Disease (CKD), which can lead to an increased risk of progression and mortality. The aim of this systematic review and meta-analysis was to perform quantitative effect of microbiota modulation for estimated Glomerular Filtration Rate (eGFR), uremic toxin (total-p cresyl/total pCS), and inflammatory marker (hs-CRP) outcome among CKD patients. Methods. Article searches were conducted from PubMed, ScienceDirect, and Cochrane Library data sources from 2010-2022. Assessment of article quality follows the rules of PRISMA (Preferred Reporting Items in Systematic Review and Meta-Analysis). Only randomized controlled trial (RCT) articles investigating the effect of symbiotic, prebiotic, of probiotic for CKD were included in the analysis. Effect size quantify from Standardized Mean Difference (SMD), using a continuous random effect model and described in the forest plot model. Results. A total of 17 RCT studies with a total 867 CKD stage 1-5 subjects (440 subjects in the intervention group and 427 subjects in the control group). The intervention duration ranging from 1-12 months. The studies included had varied on methodologies, with significant heterogenicity (I296,96%, p Conclusions. The administration of probiotic/prebiotic/symbiotic supplements to CKD patients resulted in significant improvements in e-GFR and reductions in total pCS. These results suggest the potential of symbiotic, prebiotic, and probiotic supplementation to improve CKD outcome.","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44977908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between Early Antibiotic Administration and In-Hospital Mortality in Moderate and Severe COVID-19 Patients","authors":"","doi":"10.7454/jpdi.v9i4.1019","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1019","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44790174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cutaneous Adverse Drug Reaction Among HIV-Infected Patients Starting Antituberculosis Treatment","authors":"","doi":"10.7454/jpdi.v9i4.1020","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1020","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41766060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of Heart Rate Variability, Neutrophil-Lymphocyte Ratio and Quality of Life of Patients with Depressive Symptoms in Acute Myocardial Infarction","authors":"","doi":"10.7454/jpdi.v9i4.1023","DOIUrl":"https://doi.org/10.7454/jpdi.v9i4.1023","url":null,"abstract":"","PeriodicalId":32700,"journal":{"name":"Jurnal Penyakit Dalam Indonesia","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45269083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}