Santosh University Journal of Health Sciences最新文献

{"title":"Determinants of patients' adherence to glaucoma topical therapy among Nigerian adults","authors":"Olamide John-Sam, A. Ayanniyi, R. Muhammad","doi":"10.4103/sujhs.sujhs_7_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_7_22","url":null,"abstract":"Context: Glaucoma is a leading cause of irreversible blindness globally. Among its risk factors only raised intraocular pressure is modifiable with capacity to reduce the progression of glaucoma. Adherence to intraocular pressure lowering medications is a key factor in the medical management of glaucoma. Aims: The aim of this study was to determine adherence to glaucoma topical medications and its determinants among patients. Settings and Design: This was a comparative longitudinal hospital-based study. Subjects and Methods: Ninety-six primary open-angle glaucoma patients were randomly grouped into A and B and surveyed for topical medication adherence and its determinants. All participants were counseled on medication adherence, and given dosing time schedule. Participants in Group B/reliable household members were reminded through phone calls to use their medications. Adherence level, its determinants, effect of adherence on intraocular pressure (IOP), and central visual field defect progression were assessed at baseline, 90 days, and 180 days. Statistical Analysis Used: Data normality was tested using Shapiro–Wilk test. Results were presented in frequency tables, figures, and charts. Chi-square test, Fisher's exact test, and odds ratio were used to evaluate the associations between variables where applicable. Multivariate logistic regression was employed to determine factors predicting adherence. The level of statistical significance was set at P < 0.05. Results: At baseline, 35.4% of the participants were adherent to medications, with intervention at 90 days (81.2%, A, and 79.2%, B) and at 180 days (75.0%, A, and 83.3%, B) of the participants who adhered to medications. Predictors of adherence to medications were age below 40 years (adjusted odd ratio [AOR] = 5.10; 95% confidence interval [CI], 1.18–21.82; P = 0.029) and the presence of comorbidities (AOR = 5.41; 95% CI, 1.64–17.86; P = 0.009). There was no significant difference in the mean IOP between the two groups at baseline, 90 days, and 180 days. Conclusions: There was an improvement in medication adherence following counseling. Younger age and comorbidities were notable adherence determinants.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"418 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131607578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women empowerment and information and communication technology","authors":"Tripta Bhagat","doi":"10.4103/2773-1987.367580","DOIUrl":"https://doi.org/10.4103/2773-1987.367580","url":null,"abstract":"","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130584636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived fear and anxiety as an after effect among coronavirus disease-2019 patients and their treating doctors","authors":"R. Srivastava, Ashok Kumar, Brijesh Saran, T. Bhagat, S. Bansal, A. Tyagi, Y. Srivastava","doi":"10.4103/sujhs.sujhs_28_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_28_22","url":null,"abstract":"Introduction: Coronavirus disease-2019 (COVID-19) represented a human tragedy among the general population and has been an unprecedented challenge for patients, treating doctors, and the entire world. This fact has created continuous fear, anxiety, and many more psychological discomforts such as impairment in healthy happy life, drug abuse, increased religiosity, and hopelessness, and it is also being noticed that women and women-treating doctors are found to be more prone to catch psychological disturbances. Objective: Considering all the above challenges, this study was intended to test the general health, level of fear, anxiety, and general well-being of COVID afflicted individuals and their treating doctors. Methodology: Here, the general well-being, level of anxiety, stress, and fear of COVID-19 patients and their treating doctors are examined. This study has been counducted online for COVID-19 patients (with Telephonic calls) and direct interview of treating doctors. The patient's details were taken from hospital records to contact them online. On the other side, the faculty of their treating doctors who have been physically involved in this project were examined for psychological testing. This study has been conducted in the Department of Clinical Psychology in collaboration with Medicine, Santosh Medical College, Hospitals, Ghaziabad, UP. Results and Discussion: Out of 1325 total cases, only 34% of cases took interest to provide us feedback after recovery. Approximately the similar proportion of cases, i.e., 35% did not respond but rather gave silly rationales as if they did not want to be recognized. One of the smartest groups of such population was who were proved to be highly fake as they furnished all fake identities even during their admission. It was very shocking. COVID patients did not reveal any serious psychopathology. Now if we compare the psychological profile of treating doctors (faculty and PG), their overall health has shown remarkable concerns means their mental health is affected. Conclusion: Therefore, this study concludes that the knowledge and perception about this pandemic and factors associated with anxiety/depression among frontline physicians are needed to be taken care of because it is marked among the doctors of Santosh Hospital.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132912031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of pulmonary function test and body mass index in medical and paramedical students","authors":"Namrata Lahoty, Garg Rinku","doi":"10.4103/sujhs.sujhs_25_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_25_22","url":null,"abstract":"Context: Obesity has become a serious public health issue in emerging nations, notably in India. Obesity alters the mechanics of the respiratory system, as well as exercise tolerance, gas exchanges, respiratory pattern modulation, and respiratory muscle strength and endurance, among other things. Aims: The aim was to compare the pulmonary function test parameters in normal weight, overweight, and obese young people among the medical students. Settings and Design: Obesity and overweight have become a global problem. They are the key health issues in both industrialized and developing nations today. As a result of obesity, which was defined as an excess of fat tissue in the body, a several systemic illnesses and a higher mortality rate might occur. Many bodily systems may be affected by obesity, resulting in higher rates of illness and death in the community. Subjects and Methods: The present study was carried out at Santosh Medical College in the Department of Physiology and was a cross-sectional study. Based on the body mass index (BMI), three student groups were taken as normal, overweight, and obese, which was followed by pulmonary tests conducted using spirometry, and the observations were noted and were compared among the three groups. Statistical Analysis Used: In this study, descriptive and inferential statistical analyses was performed. Continuous measurement data was shown as mean ± standard deviation (SD), whereas categorical measurement results was presented as a number (%). The significance is determined at a 5% level of significance. Assumptions: (1) Independent variables should have a normal distribution, (2) Samples selected from the population should be random, and sample cases should be independent. Conclusions: This type of study is completely novel to this geographic location as a comparison is made between two different strata (medical and paramedical students) of both genders, and it aimed to determine whether there is a difference in pulmonary function between obese, overweight, and normal weight people, especially in this section of the country. As a result, the current study in both the groups found that: (1) Forced vital capacity in overweight people was much lower than in people of normal weight and much lower in obese compared to overweight, (2) Forced expiratory volume in the 1 s in overweight people was much lower than in people of normal weight and much lower in obese compared to overweight, (3) Forced expiratory flow 25–75 in overweight people was much lower than in people of normal weight and much lower in obese compared to overweight, (4) Peak expiratory flow rate in overweight people was much lower than in people of normal weight and much lower in obese compared to overweight. As a result, all of the indices of the lung function evaluated in this study indicated a statistically significant inverse relationship with a rise in BMI. This suggests that a rise in the body mass index changes lung functioning, potentiall","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128086042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cohabitation of tuberculosis and human papillomavirus-positive infections in the development of cervical cancer","authors":"A. Raj, Harshath Parves, Ashish Kumar, B. Prabasheela, S. Dhandayuthapani","doi":"10.4103/sujhs.sujhs_40_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_40_22","url":null,"abstract":"Tuberculosis (TB) has been implicated in the pathogenesis of malignancies and may interfere with their diagnosis. TB and cancer frequently coexist and the relative immunosuppression caused by cancer or its treatment may lead to the reactivation of latent TB infections, leading to increased morbidity and mortality. Human papillomavirus (HPV) infection causes cervical cancer, particularly HPV 16 and 18 strains account for 75% of these cases. Although it is difficult to determine the exact chronology of events using data from reported diagnoses of infections, it is possible to draw preliminary conclusions regarding the relationship between co-infections and HPV infection, HPV persistence, and the development of CIN3+. This review highlights the underappreciated overlap of the cohabitation of TB and HPV + ve infection in the cause of cervical cancer.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127755098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Genitourinary cancer: A perspective review","authors":"A. Khajuria, Shilpa Kushte","doi":"10.4103/sujhs.sujhs_42_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_42_22","url":null,"abstract":"Genitourinary (GU) malignancy comprises nearly half of the cancers diagnosed in men, and the incidence of this group of cancers increases with age. The key to successful management is to define appropriate goals (cure vs. palliation) based on the history and extent of disease, physiology and life expectancy of the patients, and cost–benefit ratio of treatment options. Recently, a number of genomic and molecular studies have provided an insight into the oncogenesis and progression of GU cancers, particularly bladder, prostate, and kidney cancers. These comprehensive innovative analyses have led to new molecular classification based on the genomic expression profiles and the discovery of potential diagnostic and therapeutic molecular targets.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"209 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114667436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Charaka Shapath: A way of life","authors":"S. Jain","doi":"10.4103/2773-1987.367581","DOIUrl":"https://doi.org/10.4103/2773-1987.367581","url":null,"abstract":"","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131801731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quarantine for COVID-19: Management on mass immigration of deported illegal workers","authors":"W. Sriwijitalai, V. Wiwanitkit","doi":"10.4103/sujhs.sujhs_44_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_44_22","url":null,"abstract":"","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126175489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical mechanism of ferroptosis-mediated cancer cell death in triple-negative breast cancer: An insight","authors":"Anitha Chidamabaram, Malarvili Thekkumalai, B. Prabasheela, Tripta Bhagat, J. Batra, S. Dhandayuthapani","doi":"10.4103/sujhs.sujhs_37_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_37_22","url":null,"abstract":"Ferroptosis is a form of programmed cell death (PCD), distinct from apoptosis, that was identified in 2012. The process is driven by the iron-dependent oxidative degeneration of lipids. Ferroptosis causes cell death through the accumulation of iron-dependent lipid reactive oxygen species. Free radicals cause degradation of lipid molecules by the removal of electrons through oxidation. The process is dependent on intracellular iron as the accumulation of iron acts as a catalyst for converting peroxides into free radicals. The oxidative degradation of lipids occurs when there is depletion of the antioxidant glutathione and a loss of activity of the lipid repair enzyme glutathione peroxidase 4. The lipid peroxidation then leads to cell membrane denaturation. The biochemical mechanism behind the unique iron-dependent programmed cell death with reference to the triple negative breast cancer have been reviewed in this article.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126424232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Covid – 19 infection and treatment: Still an unfolding clinical scenario","authors":"B. Okeahialam","doi":"10.4103/sujhs.sujhs_29_22","DOIUrl":"https://doi.org/10.4103/sujhs.sujhs_29_22","url":null,"abstract":"COVID-19 infection was declared a pandemic by the World Health Organization due to its widespread nature and devastating effect on health, demography, and economics all over the world. The disease has evolved fast, changing treatment paradigms as its pathophysiology became clearer. Lately, a vaccine was introduced, and its effects and efficacy have come to be a thing of challenge as experience continues to be gained. In this case report, the author shares his experience of unfolding scenarios with treatment of the disease in his clinical environment.","PeriodicalId":326476,"journal":{"name":"Santosh University Journal of Health Sciences","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127343133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}