JKS Jurnal Kedokteran Syiah Kuala最新文献

{"title":"Invasive Dermatophytosis in HIV/AIDS Patient by Zoophilic Trichophyton verrucosum","authors":"Wilda Mahdani","doi":"10.24815/JKS.V21I1.19565","DOIUrl":"https://doi.org/10.24815/JKS.V21I1.19565","url":null,"abstract":"Invasive dermatophytosis is a dermatophyte infection characterized by fungal invasion into deeper skin tissue including the dermis and subcutaneous areas. Herein, a man who was an HIV/AIDS sufferer was reported to develop an unusually invasive dermatophytosis in the form of nodules and ulceration. His CD4+ cells count was 88 cells/µl with a percentage of 1.87%. Self-medication with topical antibiotics did not respond. Microbiological examination was carried out including direct potassium hydroxide preparation and fungal culture. The etiologic diagnosis of invasive dermatophytosis by Trichophyton verrucosum  was established. This is one of the zoophilic fungus that causes ringworm in cattle. It was suspected that the patient was inoculated due to contact with fomites containing fungi while working as a construction worker. Dermatophytes can cause atypical infections with a completely unexpected appearance in immunocompromised patients. The diagnosis is largely determined by a high level of clinical suspicion followed by microbiological examination.","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83287437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ACUTE KIDNEY INJURY (AKI) PADA KEHAMILAN","authors":"Satriyo Dwi Suryantoro, Djoko Santoso, Sarah Firdausa","doi":"10.24815/JKS.V21I1.19284","DOIUrl":"https://doi.org/10.24815/JKS.V21I1.19284","url":null,"abstract":"Acute Kidney Injury (AKI) in pregnancy remains a cause for fetomaternal morbidity and mortality, particularly in developing countries. Hypertensive complications of pregnancy (preeclampsia/eclampsia, HELLP syndrome) remains the leading cause of AKI in pregnancy. A set of systemic and renal physiological adaptive mechanisms occur during a normal gestation that will cause several changes in laboratory parameters of renal function, electrolytes, fluid and acid – base balance. Diagnosis of AKI in pregnancy is based on the serum creatinine increase and reduction of urine output. Management of AKI in pregnancy requires a multidisciplinary approach between nephrologists and obstetricians for optimizing care for both mother and child. In approaching AKI in pregnant woman, emphasis should be placed on making early and accurate diagnosis to allow prompt intervention and to facilitate recovery from AKI.","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91112556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TEROBOSAN BARU PENGENDALIAN KESUBURAN PEREMPUAN DENGAN MENGGUNAKAN KURKUMIN","authors":"Rajuddin Rajuddin","doi":"10.24815/JKS.V21I1.19333","DOIUrl":"https://doi.org/10.24815/JKS.V21I1.19333","url":null,"abstract":"Peran kurkumin pada sistem reproduksi dapat dipakai pada pengaturan kesuburan melalui beberapa cara, yaitu: [1] Kurkumin menyebabkan kadar LH serum menurun dan tidak memberikan gambaran lonjakan LH pada pertengahan siklus haid, sehingga berperan menghambat ovulasi; [2] Kurkumin menyebabkan kadar estradiol serum rendah, progesteron serum rendah, tampilan VEGF di endometrium rendah dan ketebalan endometrium menjadi tipis sehingga dapat mencegah nidasi; [3] Kurkumin menyebabkan pertumbuhan folikel ovarium kecil, sehingga kecil kemungkinannya ovulasi terjadi. Untuk pengembangan ke depan, penelitian kurkumin perlu dilakukan  lebih lanjut supaya dapat menghasilkan temuan-temuan inovatif baru yang bermanfaat untuk masyarakat, sehingga kurkumin dapat dipergunakan sebagai obat pengatur kesuburan atau sebagai obat baru untuk kontrasepsi. Universitas Syiah Kuala diharapkan menjadi pusat pengembangan riset lebih lanjut terkait rempang kunyit sebagai antifertilitas. Sebagai bahan riset, kunyit sangatlah mudah diperoleh karena populasi tumbuhan ini tersebar dalam jumlah besar di berbagai tempat di Aceh. Penelitian yang menghasilkan temuan-temuan inovatif ini merupakan sumbangsih yang sangat bermanfaat untuk meningkatkan kesehatan dan pemakaian kontrasepsi rakyat Indonesia, khususnya Aceh sebagai wujut pengabdian Universitas Syiah Kuala kepada masyara­kat.","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"201 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85782452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cathelicidin, vitamin D3 dan imunitas terhadap tuberkulosis","authors":"Yunita Arliny, Maryatun Hasan","doi":"10.24815/JKS.V20I3.18610","DOIUrl":"https://doi.org/10.24815/JKS.V20I3.18610","url":null,"abstract":"Abstrak. Tuberkulosis (TB) merupakan salah satu penyakit infeksi yang menjadi masalah di dunia. Risiko untuk mendapatkan infeksi TB dipengaruhi oleh imunitas alamiah melawan mikobakteria. Peptida antimikroba merupakan salah satu barrier pertahanan alamiah. Cathelicidin adalah suatu peptida anti mikroba yang berperan pada proses imunitas terhadap TB. Cathelicidin Leusin Leusin-37 (LL-37) merupakan satu-satunya cathelicidin yang ada pada manusia dan dapat diekspresikan dari beberapa sel temasuk sel imun. Inducer Cathelicidin yang paling poten adalah 1,25-dihydroxyvitamin D3 yang merupakan bentuk aktif vitamin D 25(OH)D3. Tinjauan pustaka ini membahas tentang cathelicidin, vitamin D3 dam peranannya pada imunitas terhadap TB.Kata kunci: Cathelicidin, 1,25-dihydroxyvitamin D3, vitamin D 25(OH)2D3, imunitas, TuberkulosisAbstract. Tuberculosis is one of the most important infectious diseases worldwide. The susceptibility to this disease depends to great extent on the innate immune response against mycobacteria. Antimicrobial peptides are one of the natural defense barriers. Cathelicidin Leucine Leucine-37 (LL-37) is the only cathelicidin present in humans and synthesized by several cells including immune cells. The most effective inducer of Cathelicidin is 1,25-dihydroxyvitamin D3 (1,25(OH)2 D3), which is an active form of vitamin D 25(OH)D3. This review discusses cathelicidin, vitamin D3 and its role in immunity against TBKeywords: Cathelicidin, 1,25-dihydroxyvitamin D3, vitamin D 25(OH)D3, immunity, Tuberkulosis","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81916423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbiologically documented infection and antimicrobial sensitivities in pediatric malignancy patients with febrile neutropenia at Dr Saiful Anwar Hospital, Malang, Indonesia","authors":"S. L. Winaputri, D. Husada, B. Utomo, I. Ratridewi, Susanto Nugroho, I. Ugrasena, P. Basuki, I. Ismoedijanto","doi":"10.24815/JKS.V21I1.20903","DOIUrl":"https://doi.org/10.24815/JKS.V21I1.20903","url":null,"abstract":"Abstract. Background: Febrile neutropenia in malignancy children increase the risk of infection, morbidity and mortality. Microbiologically documented infection in pediatric malignancy has not been studied in Saiful Anwar Hospital. Purpose: Determine profile of blood, urine, sputum, and wound bed culture and antimicrobial sensitivities pattern in pediatric malignancy patients with febrile neutropenia. Methods: Pediatric malignancy patients with febrile neutropenia and microbiologically documented infection admitted to dr Saiful Anwar General Hospital Malang, were studied from 2016 to 2019.  Bacterial and fungal etiology were identified, along with antimicrobial sensitivities patterns. Results: 53 (17%) of 307 pediatric malignancy patients with febrile neutropenia experienced 75 episodes of microbiologically documented infection. 40 (53,3%) gram-negative and 34 (45,3%) gram-positive isolated from 75 isolated pathogens. The most common gram-negative were Klebsiella pneumonia (n=15) and Escherichia coli (n=8). The most common gram-positive were Coagulase-negative Staphylococci (n=14) and Enterococcus faecalis (n=7). Escherichia coli, Coagulase-negative Staphylococci, Enterococcus faecalis, and Staphylococcus aureus were 100% sensitive to all tested antimicrobials. Klebsiella pneumonia and Acinetobacter baumanni were 100% sensitive to almost all tested antimicrobials. Pseudomonas aeruginosa was found less sensitive (0-80%) to all tested antimicrobials. Conclusion: Investigation of antimicrobial sensitivities of these organisms may guide successful antimicrobial therapy and improve quality of pediatric malignancy care. Abstrak. Latar Belakang: Demam neutropenia pada keganasan anak meningkatkan risiko infeksi, morbiditas dan mortalitas. Microbiologically Documented Infection merupakan masalah utama di dunia, namun belum dilakukan penelitian di RSUD Dr. Saiful Anwar. Tujuan: Melihat gambaran kultur darah, urine, sputum, dan dasar luka dan pola sensitivitas antimikroba pada keganasan anak dengan demam neutropenia. Metode: Pasien keganasan anak dengan demam neutropenia di bangsal Hemato-onkologi Departemen Ilmu Kesehatan Anak RSUD Dr. Saiful Anwar Malang dan terdiagnosis Microbiologically Documented Infection pada tahun 2016-2019, ditentukan etiologi, serta pola sensitivitas antimikroba. Hasil: Dari 307 pasien keganasan anak dengan demam neutropenia, 53(17%) pasien mengalami 75 episode microbiologically documented infection. Didapatkan 40(53,3%) bakteri gram negatif dan 34(45,3%) gram positif dari 75 hasil kultur. Bakteri gram negatif yang paling banyak ditemukan adalah Klebsiella pneumonia (n=15) dan Escherichia coli (n=8), serta Coagulase-negative Staphylococci (n=14) dan Enterococcus faecalis (n=7) pada gram positif. Escherichia coli, Coagulase-negative Staphylococci, Enterococcus faecalis, dan Staphylococcus aureus 100% sensitif terhadap semua antimikroba yang diuji. Klebsiella pneumonia dan Acinetobacter baumanni 100% sensitif terhadap hampir semua a","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-11-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73967799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gambaran tingkat depresi terhadap kejadian peningkatan interdialytic weight gain pada pasien penyakit ginjal kronik yang menjalani hemodialisis di Rumah Sakit Umum Dr. Zainal Abidin, Banda Aceh","authors":"Safina Khairidina, Maryatun Hasan, Mirfandi Amirsyah, Maimun Syukri, Rina Hastuti Lubis","doi":"10.24815/jks.v20i2.18503","DOIUrl":"https://doi.org/10.24815/jks.v20i2.18503","url":null,"abstract":"Abstrak. Penyakit ginjal kronis (PGK) merupakan penyakit yang dapat mengakibatkan penderitanya mengalami stress jangka panjang dan akhirnya bermanifestasi menjadi depresi. Depresi yang ditimbulkan dapat mempengaruhi perilaku pasien dalam hal pengaturan cairan sehingga dapat berakibat terhadap peningkatan Interdialytic Weight Gain (IDWG). Jika IDWG meningkat maka akan menimbulkan komplikasi yang dapat menghambat keberhasilan terapi hemodialisis.  Penelitian ini bertujuan untuk mengetahui gambaran tingkat depresi terhadap terjadinya peningkatan Interdialytic Weight Gain pada pasien PGK yang menjalani hemodialisis di RSUDZA Banda Aceh. Jenis penelitian ini adalah deskriptif analitik dengan pendekatan cross sectional. Pengumpulan data dilakukan pada bulan Desember 2019 menggunakan teknik accidental sampling dengan responden adalah pasien di unit hemodialisis RSUDZA Banda Aceh. Pengumpulan data dilakukan dengan menggunakan kuesioner Hamilton Rating Scale for Depression kemudian dilakukan analisis univariat untuk mengatahui gambaran dari penelitian dan bivariat dengan menggunakan uji korelasi Spearman. Berdasarkan hasil analisis statistik dengan menggunakan uji Spearman, didapatkan p value sebesar 0,000 (p0,05) dengan koefisien korelasi Spearman sebesar 0,729. Hal ini menunjukkan adanya hubungan yang signifikan antara tingkat depresi dengan peningkatan IDWG pada pasien PGK yang menjalani hemodialisis di RSUDZA Banda Aceh.Kata Kunci: Penyakit Ginjal Kronis, Hemodialisis, Depresi, Interdialytic Weight GainAbstract. Chronic kidney diasease (CKD) might cause stress which generally leads to depression. Depression is correlated to significant impairment in a patient's daily life, such as excessive Interdialytic Weight Gain (IDWG) caused by an overload of fluids. Excessive Interdialytic Weight Gain might also cause other complications that are able to interfere the process of hemodialysis therapy. The objective of this research was to identify the overview of and the correlation between depression types and Interdialytic Weight Gain (IDWG) of the chronic kidney disease patients undergoing hemodialysis therapy in dr. Zainoel Abidin Regional Public Hospital of Banda Aceh. This descriptive analytical research was conducted by means of a cross-sectional study approach. The data were collected in December 2019 by using an accidental sampling technique. The data were collected by distributing the Hamilton Rating Scale for Depression. Those data were then analyzed by using a univariate data analysis and a bivariate data analysis, especially the Spearman Correlation Coefficient. Based on the statistical analysis with the Spearman test, p-value of 0.000 (p0.05) with a Spearmen Correlation Coefficient of 0.729 was found. Hence, a significant correlation between depression levels or types and IDWG in chronic kidney disease patients undergoing hemodialysis in dr. Zainoel Abidin Regional Public Hospital of Banda Aceh was indicated.Keywords: Chronic Kidney Disease, hemodia","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82918554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mayer-Rokitansky-Küster-Hauser syndrome","authors":"Cut Meurah Yeni, Khairussani Khairussani, Wardatul Bararah","doi":"10.24815/jks.v20i1.18299","DOIUrl":"https://doi.org/10.24815/jks.v20i1.18299","url":null,"abstract":"Abstrak. Mayer–Rokitansky–Küster–Hauser syndrome (MRKH) adalah suatu sindrom yang ditandai dengan aplasia uterus, serviks, dan 2/3 vagina bagian atas karena perkembangan yang tidak sempurna dari duktus Mullerian. Dilaporkan seorang perempuan berusia 26 tahun yang mengeluh belum pernah menstruasi sampai saat ini. Secara fenotip pasien tampak sebagai perempuan yang memiliki perawakan normal. Payudara dan distribusi pertumbuhan rambut aksila serta kemaluan berkembang normal, disertai pertumbuhan lemak pada bokong dan paha. Tuba fallopi, rahim, dan vagina 2/3 proksimal tidak terbentuk. Pada pemeriksaan klinis ginekologi tampak introitus vagina dengan sonde vagina sepanjang 2 cm. Pemeriksaan USG abdominal, uterus berupa garis dan kedua ovarium sulit dinilai. Pemeriksaan MRI didapatkan agenesis uterus dan agenesis adnexa. Pemeriksaan analisa hormonal, LH 9,81 mIU/mL, FSH 6,87 mIU/mL, progesteron 0,51 ng/mL, estradiol 46,4 pg/mL, testosteron 60,45 mg/dl, TSH 1,216 mIU/L, T4 11 ug/dl, serta analisa kromosom 46XX. Pasien direncanakan untuk dilakukan vaginoplasti.Kata kunci : sindrom MRKH, anomali duktus Mulleri, vaginoplastiAbstract. Mayer–Rokitansky–Küster–Hauser syndrome (MRKH) is a syndrome characterized by uterine, cervix, and the two third of upper vagina aplasia which is the cause of incomplete development of the Müllerian duct. Reported a case of woman 26 years old, patient has not menstruated until now. The phenotype of the patient appears to be female, and with normal stature. Breast, axilla dan pubic hair distribution, fatty in buttocks and thigh developed normally. Fallopian tubes, uterine and 2/3 upper part of vagina were not formed. On gynecological clinical examination, found vaginal introitus with a vaginal sonde was 2 cm. On abdominal ultrasound examination, the uterus was seen as a line and both ovaries were difficult to assess. MRI examination obtained theresults as uterine and adnexa agenesis. Hormonal analysis showing LH 9.81 mIU/mL, FSH 6.87 mIU/mL, progesteron 0.51 ng/mL, estradiol 46.4 pg/mL, testosterone 60.45 mg/dl, TSH 1.216 mIU/L, T4 11 ug/dl, and chromosome examination is 46 XX. Patient are planned for vaginoplasty. Key words: MRKH syndrome, mullerian duct anomalies, vaginoplasty","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88390191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gambaran dislipidemia pada pasien stroke akut di Rumah Sakit Umum Daerah Arifin Achmad Provinsi Riau periode Januari-Desember 2019","authors":"D. P. Nugraha, Eka Bebasari, Sahwal Sahputra","doi":"10.24815/jks.v20i1.18294","DOIUrl":"https://doi.org/10.24815/jks.v20i1.18294","url":null,"abstract":"Abstrak. Stroke adalah penyakit gangguan fungsional otak yang timbul mendadak dan berlangsung lebih dari 24 jam atau berakhir dengan kematian tanpa diketahui penyebab yang jelas selain gangguan vaskuler. Stroke secara umum diklasifikasikan menjadi stroke iskemik atau stroke non hemoragik dan stroke hemoragik. Salah satu faktor risiko terjadinya stroke adalah dislipidemia. Tujuan penelitian ini adalah untuk mengetahui gambaran dislipidemia pada pasien stroke akut di RSUD Arifin Achmad Provinsi Riau Periode Januari–Desember 2019. Desain penelitian yang digunakan adalah penelitian deskriptif  dengan rancangan cross sectional menggunakan data sekunder rekam medis pasien stroke akut di  RSUD Arifin Achmad Provinsi Riau  Periode Januari-Desember 2019 dengan jumlah sampel sebanyak 103 kasus. Hasil penelitian menunjukkan stroke banyak terjadi pada jenis kelamin laki-laki yaitu 63 orang (61,2%). Usia terbanyak terjadi pada rentang usia 51-65 tahun sebanyak 54 (52,4%). Jenis stroke terbanyak adalah stroke hemoragik yaitu 59 orang (57,3%). Kadar kolesterol total terbanyak pada  rentang normal yaitu sebanyak 46 orang (44,7%). Kadar High Density Lipoprotein (HDL)  terbanyak pada rentang normal yaitu sebanyak 49 orang (47,6%). Kadar Low Density  Lipoprotein (LDL) terbanyak pada kategori tinggi sebanyak 26 orang (25,2%) dan normal tapi berisiko sebanyak 26 orang (25,2%). Kadar trigliserida terbanyak pada kategori normal sebanyak 65 orang (63,1%). Terdapat 17 orang (16,5%) pasien dislipidemia, sebanyak 9 orang (52,9%) adalah stroke iskemik. Kesimpulan dari penelitian ini adalah dislipidemia lebih banyak terjadi pada stroke iskemik disbanding stroke hemoragik.Kata kunci:  dislipidemia, stroke, stroke non hemoragikAbstract. Stroke is a disease of the brain functional disorders that arises suddenly and lasts more than 24 hours or ends in death situation without a known cause other than vascular disorders. Strokes are generally classified into ischemic stroke (non-hemorrhagic) and hemorrhagic stroke, One of the risk factors of stroke is dyslipidemia. The aim of this study was to describe dyslipidemia in acute stroke patients at Arifin Achmad Regioal General Hospital of Riau Province in January to December 2019. This was a descriptive study design with cross sectional study method by using secondary data of the acute stroke patient's medical record at Arifin Achmad Regional General Hospital of Riau Province in January to December 2019 with a total sample of 103 cases. The results show that stroke is more common in male that is 63 (61.2%) cases, and the majority happened within the 51-65 years age groups with 54 (52.4%) cases. Most of the stroke’s type in patients were hemorrhagic stroke in 59 (57.3%) cases. Highest total of cholesterol level remains normal in 46 (44.7%) cases. The majority of patients still presented with normal level of High Density Lipoprotein (HDL) in 49 (47.6%) cases. In contrary, most patients presented with high level of Low Density Lipoprotein","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"281 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72435685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bakteri patogen pada telepon genggam mahasiswa fakultas kedokteran Universitas Airlangga angkatan 2014","authors":"Ribka B. A Mboe, M. Purwanta, Lilik Djuari","doi":"10.24815/jks.v20i1.18298","DOIUrl":"https://doi.org/10.24815/jks.v20i1.18298","url":null,"abstract":"Abstract. Infeksi adalah salah satu dari isu kesehatan yang disebabkan oleh mikroorganisme patogen dan salah satu mikroorganisme yang tersering adalah Streptococcus. Terdapat 616 kasus faringitis di dunia yang disebabkan oleh Streptococcus. Penyakit tersebut dapat menimbulkan berbgai komplikasi lain bila tidak diterapi dengan baik. Pengobatan menggunakan antibiotik memiliki risiko terjadinya resistensi. Oleh sebab itu, diperlukan pengembangan penelitian pada herbal sebagai pengobatan. Bunga kamboja putih (Plumeria alba) diketahui memiliki aktivitas antibakteri melawan berbagai macam mikroorganisme. Dengan latar belakang tersebut, tujuan dari penelitian ini adalah untuk menentukan adanya aktivitas antimikroba dari Plumeria alba terhadap Streptococcus pyogenes yang dapat diamati dari Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM). Penelitian ini dikerjakan menggunakan metode eksperimental. Metode dilusi agar digunakan untuk menentukan KHM dan KBM. Konentrasi yang digunakan pada penelitian ini adalah 250 mg/ml, 125 mg/ml, 62,50 mg/ml, 31.25 mg/ml, 15,63 mg/m, 7,81 mg/ml, 3,91 mg/ml, 1,95 mg/ml, 0,98 mg/ml, kontrol positif (+) dan kontrol negatif (-). Melalui observasi dari penelitian ini, KHM tidak dapat ditentukan. Nilai dari KBM adalah 7,81 mg/ml yang menunjukkan konsentrasi dimana tidak didapatkan pertumbuhan koloni bakteri. Ekstrak etanol dari bunga kamboja putih (Plumeria alba) memiliki aktivitas antimikroba terhadapt Streptococcus pyogenes. Dalam studi in vitro ini menggunakan metode dilusi agar, KBM untuk Streptococcus pyogenes adalah 7,81 mg/ml.Kata Kunci: Bakteri patogen, telepon genggam, identifikasi bakteriAbstract. Recently people use mobile phone in the places that have a high density of microorganisms such as in the hospital, in the kitchen, and in the toilet. Some studied stated that mobile phones played a role in transmission of pathogenic bacteria. Brady et al., reported that 9% to 25% of mobile phones were contaminated with pathogenic bacteria. This research was based on experimental laboratory. The samples were mobile phone, swabbed by wet sterile cotton bud and placed on MacConkey Agar plate and Blood Agar plate. The isolated bacteria were checked by Gram stained. Catalase test for Gram-positive cocci bacteria and specific biochemical test for Gram-negative bacilli bacteria were used to determine the genus of the bacteria. The samples were mobile phone belong to 2014-entering-year students of Medical Faculty of Airlangga University. The sampling method was simple random sampling. This experiment found that 100% of the samples were Staphylococcus spp. positive, 3,3% were Shigella spp. positive and 3,3% were Proteus spp. positive. From this experiment could be concluded that mobile phone  belong to 2014-entering-year students of Medical Faculty of Airlangga University were contaminated by pathogenic bacteria. The result of this experiment found that Shigella spp. and Proteus spp. were pathogenic bacteria on mo","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"22 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73282760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efektivitas gel ekstrak jahe gajah (Zingiber officinale var rosc) terhadap kecepatan kesembuhan luka abrasi pada tikus putih (Rattus novergicus) jantan strain wistar","authors":"Fatah Jati Pamungkas","doi":"10.24815/jks.v22i1.23540","DOIUrl":"https://doi.org/10.24815/jks.v22i1.23540","url":null,"abstract":"Abstract. Background: Abrasion wound is the release of the skin surface caused by friction with rough surface, ginger anti-inflammatory compound so that it can accelerate the healing of abrasion wounds. Objective: the effectiveness of healing abrasion wounds with gel application of ginger extract (Zingiber Officlinale Var Rosc) on white rats (Rattus norvegicus). Method:  True experimental with post test only control group design. The study was conducted for 7 days with samples divided into 4 groups, P1 (NaCl 0.9%), P2 (Gel 0%), P3 (Ginger Gel 8%), P4 (Ginger Gel 12%). Application of extract gel was done on days 1, 3 and 5. Wound area observed on day 7. Data analyzed using the One Way ANOVA test. Results: The results showed abrasion wound area day 7 at P1 = 1.47 cm2, P2 = 0.58 cm2, P3 = 0.31 cm2, P4 = 0 cm2, healing speed P1 = 4.9% / day, P2 = 10.6% / day, P3 = 12.31% / day, P4 = 14.2% / day. One way ANOVA test results showed a significant effect (p 0.05). Conclusion: Elephant ginger extract extract (Zingiber officinale var rosc) can accelerate healing of abrasion wounds in white rats (Rattus norvegicus).","PeriodicalId":32458,"journal":{"name":"JKS Jurnal Kedokteran Syiah Kuala","volume":"81 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86218461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}