Efektivitas gel ekstrak jahe gajah (Zingiber officinale var rosc) terhadap kecepatan kesembuhan luka abrasi pada tikus putih (Rattus novergicus) jantan strain wistar

JKS Jurnal Kedokteran Syiah Kuala Pub Date : 2020-03-13 DOI:10.24815/jks.v22i1.23540

Fatah Jati Pamungkas

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Abstract

Abstract. Background: Abrasion wound is the release of the skin surface caused by friction with rough surface, ginger anti-inflammatory compound so that it can accelerate the healing of abrasion wounds. Objective: the effectiveness of healing abrasion wounds with gel application of ginger extract (Zingiber Officlinale Var Rosc) on white rats (Rattus norvegicus). Method: True experimental with post test only control group design. The study was conducted for 7 days with samples divided into 4 groups, P1 (NaCl 0.9%), P2 (Gel 0%), P3 (Ginger Gel 8%), P4 (Ginger Gel 12%). Application of extract gel was done on days 1, 3 and 5. Wound area observed on day 7. Data analyzed using the One Way ANOVA test. Results: The results showed abrasion wound area day 7 at P1 = 1.47 cm2, P2 = 0.58 cm2, P3 = 0.31 cm2, P4 = 0 cm2, healing speed P1 = 4.9% / day, P2 = 10.6% / day, P3 = 12.31% / day, P4 = 14.2% / day. One way ANOVA test results showed a significant effect (p 0.05). Conclusion: Elephant ginger extract extract (Zingiber officinale var rosc) can accelerate healing of abrasion wounds in white rats (Rattus norvegicus).

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姜黄提取凝胶(Zingiber officinale var rosc)对白老鼠(Rattus novergicus)损伤恢复速度的影响

摘要背景:擦伤性伤口是由于皮肤表面与粗糙表面摩擦引起的释放，生姜的抗炎复方使其能加速擦伤性伤口的愈合。目的:观察姜提取物凝胶敷对褐家鼠(Rattus norvegicus)擦伤创面愈合的影响。方法:真实实验，后验组设计。试验为期7 d，将样品分为4组，P1 (NaCl 0.9%)、P2(凝胶0%)、P3(姜凝胶8%)、P4(姜凝胶12%)。第1、3、5天应用提取液凝胶。第7天观察伤口面积。数据分析采用单因素方差分析检验。结果:第7天擦伤创面面积P1 = 1.47 cm2, P2 = 0.58 cm2, P3 = 0.31 cm2, P4 = 0 cm2，愈合速度P1 = 4.9% / d, P2 = 10.6% / d, P3 = 12.31% / d, P4 = 14.2% / d。单因素方差分析结果显示显著影响(p 0.05)。结论:象姜提取物(Zingiber officinale var rosc)可促进褐家鼠擦伤创面愈合。

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JKS Jurnal Kedokteran Syiah Kuala

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12 weeks