Precision Radiation Oncology最新文献

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Dosimetric and Radiobiological Impact of Flattening Filter‐Free Beam and Dose Calculation Algorithm Using RapidArc Plans for Cervical Cancer Treatment 使用RapidArc计划进行宫颈癌治疗的平坦化无滤光剂光束和剂量计算算法的剂量学和放射生物学影响
Precision Radiation Oncology Pub Date : 2023-08-17 DOI: 10.1002/pro6.1207
S. Manna, Sharad Singh, P. Gupta, Ragul T
{"title":"Dosimetric and Radiobiological Impact of Flattening Filter‐Free Beam and Dose Calculation Algorithm Using RapidArc Plans for Cervical Cancer Treatment","authors":"S. Manna, Sharad Singh, P. Gupta, Ragul T","doi":"10.1002/pro6.1207","DOIUrl":"https://doi.org/10.1002/pro6.1207","url":null,"abstract":"The aim of this study is to quantify the potential benefits of a flattening filter‐free (FFF) beam and implement a dose‐computation algorithm for cervical radiotherapy through dosimetric and radiobiological analyses using RapidArc.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44177666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Auto‐segmentation of the clinical target volume using a domain‐adversarial neural network in patients with gynaecological cancer undergoing postoperative vaginal brachytherapy 在接受阴道术后近距离放疗的妇科癌症患者中,使用域对抗神经网络进行临床靶体积的自动分割
Precision Radiation Oncology Pub Date : 2023-08-07 DOI: 10.1002/pro6.1206
Junfang Yan, Xue Qin, C. Qiao, Jiawei Zhu, Lina Song, Mi Yang, Shaobin Wang, Lu Bai, Zhikai Liu, J. Qiu
{"title":"Auto‐segmentation of the clinical target volume using a domain‐adversarial neural network in patients with gynaecological cancer undergoing postoperative vaginal brachytherapy","authors":"Junfang Yan, Xue Qin, C. Qiao, Jiawei Zhu, Lina Song, Mi Yang, Shaobin Wang, Lu Bai, Zhikai Liu, J. Qiu","doi":"10.1002/pro6.1206","DOIUrl":"https://doi.org/10.1002/pro6.1206","url":null,"abstract":"For postoperative vaginal brachytherapy (POVBT), the diversity of applicators complicates the creation of a generalized auto‐segmentation model, and creating models for each applicator seems difficult due to the large amount of data required. We construct an auto‐segmentation model of POVBT using small data via domain‐adversarial neural networks (DANNs).","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47219182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progress in radiotherapy for small‐cell lung cancer 小细胞肺癌放射治疗的进展
Precision Radiation Oncology Pub Date : 2023-07-31 DOI: 10.1002/pro6.1205
Fujun Yang, Huan Zhao
{"title":"Progress in radiotherapy for small‐cell lung cancer","authors":"Fujun Yang, Huan Zhao","doi":"10.1002/pro6.1205","DOIUrl":"https://doi.org/10.1002/pro6.1205","url":null,"abstract":"Small‐cell lung cancer (SCLC) is a highly aggressive neuroendocrine tumor that is prone to spread extensively. Compared to non‐small‐cell lung cancer (NSCLC), SCLC treatment progresses slowly. Although SCLC is highly sensitive to chemotherapy during the initial treatment, most patients still experience resistance and recurrence after receiving chemotherapy. A meta‐analysis demonstrated that thoracic radiotherapy (TRT) improves overall survival in SCLC. The results of the CALGB and CONVERT trials provide evidence for the efficacy of once‐daily high‐dose TRT. TRT at 60 Gy administered twice daily significantly improved survival without increasing toxicity. The long‐standing debate over the optimal timing of radiotherapy has not been fully resolved. SBRT has excellent local control rates and is a safe and effective treatment option for patients with stage I or II SCLC. Prophylactic cranial irradiation (PCI) is used to reduce treatment‐related neurotoxicity to the extent that there has been a recent discussion on whether magnetic resonance imaging (MRI) monitoring can replace PCI. Radiotherapy combined with immunotherapy significantly improves the survival rate of patients with NSCLC; however, its clinical effectiveness has not been systematically explored in patients with SCLC. Therefore, we summarize the evolving therapeutic strategies, (TRT for limited stage‐SCLC and consolidative TRT for extensive stage‐SCLC) and improved radiotherapy techniques (role of SBRT in stage I or II node‐negative SCLC, progress of PCI, and stereotactic radiosurgery), and discuss the possibilities and prospects of radiotherapy combined with immunotherapy for SCLC.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47930366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elevated pretreatment squamous cell Carcinoma Antigen indicates unfavorable treatment outcomes in cervical cancer patients receiving definitive radiotherapy 前处理鳞状细胞癌抗原升高表明接受明确放疗的宫颈癌症患者的治疗结果不良
Precision Radiation Oncology Pub Date : 2023-07-16 DOI: 10.1002/pro6.1202
Dingchao Liu, Weiping Wang, Z. Zeng, Xiaoliang Liu, Yuncan Zhou, Chen Wang, Xiaoyang Li, K. Hu
{"title":"Elevated pretreatment squamous cell Carcinoma Antigen indicates unfavorable treatment outcomes in cervical cancer patients receiving definitive radiotherapy","authors":"Dingchao Liu, Weiping Wang, Z. Zeng, Xiaoliang Liu, Yuncan Zhou, Chen Wang, Xiaoyang Li, K. Hu","doi":"10.1002/pro6.1202","DOIUrl":"https://doi.org/10.1002/pro6.1202","url":null,"abstract":"To investigate the prognostic value of pretreatment squamous cell carcinoma antigen (SCC Ag) levels for treatment failure prediction in patients with cervical cancer.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42821106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Whole‐breast irradiation with lumpectomy cavity boost and regional nodal irradiation: Dosimetric comparison of 3D‐CRT using sequential boost and dual partial‐arc VMAT using simultaneous integrated boost 肿块切除腔增强和区域淋巴结照射的全乳腺照射:顺序增强的3D-CRT和同时集成增强的双部分弧VMAT的剂量比较
Precision Radiation Oncology Pub Date : 2023-06-01 DOI: 10.1002/pro6.1203
A. Poojari, S. Sapru, R. Khurana, M. Rastogi, R. Hadi, A. Gandhi, S. Mishra, Amit Kumar Srivastava, A. Bharati
{"title":"Whole‐breast irradiation with lumpectomy cavity boost and regional nodal irradiation: Dosimetric comparison of 3D‐CRT using sequential boost and dual partial‐arc VMAT using simultaneous integrated boost","authors":"A. Poojari, S. Sapru, R. Khurana, M. Rastogi, R. Hadi, A. Gandhi, S. Mishra, Amit Kumar Srivastava, A. Bharati","doi":"10.1002/pro6.1203","DOIUrl":"https://doi.org/10.1002/pro6.1203","url":null,"abstract":"To compare volumetric modulated arc therapy (VMAT) with simultaneous tumor bed boost (dpSIB‐VMAT) to the whole breast and regional nodal irradiation (RNI) against standard three‐dimensional conformal radiotherapy plus RNI with sequential tumor bed boost (3D‐CRT‐seqB).","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49301807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical study of analgesia in brachytherapy for cervical cancer 宫颈癌近距离放疗镇痛的临床研究
Precision Radiation Oncology Pub Date : 2023-06-01 DOI: 10.1002/pro6.1194
Liu Mei, Wu Hai‐Yan, Li Jian, Ou Meng‐Yu, Sun Shu‐Fang, Tang Ying, Zhao Xiu‐Juan
{"title":"Clinical study of analgesia in brachytherapy for cervical cancer","authors":"Liu Mei, Wu Hai‐Yan, Li Jian, Ou Meng‐Yu, Sun Shu‐Fang, Tang Ying, Zhao Xiu‐Juan","doi":"10.1002/pro6.1194","DOIUrl":"https://doi.org/10.1002/pro6.1194","url":null,"abstract":"Abstract Objective This study investigated the analgesic effects in patients with cervical cancer during brachytherapy. Methods In this prospective study, 100 patients with cervical cancer who were admitted to Chongqing University Cancer Hospital between July 2021 and April 2022 were randomly divided into an analgesia group (n = 50) and a control group (n = 50). The visual analog scale (VAS) scores at applicator placement‐T1, CT‐scan‐T2, and removal ‐T3, self‐rating anxiety scale (SAS) and self‐rating depression scale (SDS) scores before brachytherapy, short‐term clinical efficacy, and patient satisfaction were compared between the two groups. Results The VAS score of the analgesia group was significantly different at T1 (0 vs. 4.34±1.02, t = 67.40, p < 0.001), but not in the control group; however, there was no significant difference between the two groups at T2 ( t = ‐0.49, p = 0.623) and T3 ( t = ‐0.12, p = 0.912). The SAS and SDS scores first decreased and then increased in the analgesic group and increased in the control group with increasing brachytherapy time. Except for the first measurement, the differences between the two groups were statistically significant (all p < 0.001). The application of interstitial implantation ( p = 0.027), local efficacy ( p = 0.047), and patient satisfaction rates ( p = 0.025) were higher in the analgesic group than in the control group. Conclusion Analgesia can relieve pain, maintain physical and mental health, and improve outcomes and patient satisfaction rates for cervical cancer.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135776182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Characterization of GafchromicTM EBT4 film with clinical kV/MV photons and MeV electrons 用临床kV/MV光子和MeV电子表征GafchromicTM EBT4薄膜
Precision Radiation Oncology Pub Date : 2023-06-01 DOI: 10.1002/pro6.1204
F. Guan, Huixiao Chen, E. Draeger, Yuting Li, R. Aydin, C. Tien, Zhe Chen
{"title":"Characterization of GafchromicTM EBT4 film with clinical kV/MV photons and MeV electrons","authors":"F. Guan, Huixiao Chen, E. Draeger, Yuting Li, R. Aydin, C. Tien, Zhe Chen","doi":"10.1002/pro6.1204","DOIUrl":"https://doi.org/10.1002/pro6.1204","url":null,"abstract":"A newly developed GafchromicTM EBT4 film model was released recently. According to the vendor‐stated specifications, this new model maintains major features of its more recent predecessor, EBT3, but has a great improvement in the signal‐to‐noise ratio (SNR). The purpose of this study was to fully characterize the EBT4 model by testing its dose response dependence on beam energy using clinical photon and electron beams and validating its improvement in SNR.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44908790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Erb‐(IL10)2 ameliorates radiation‐induced skin injury through eliminate oxygen free radicals Erb‐(IL10)2通过消除氧自由基改善辐射诱导的皮肤损伤
Precision Radiation Oncology Pub Date : 2023-06-01 DOI: 10.1002/pro6.1193
Jiahe Xu, Jiaxing Zhu, Qi Zhao, J. Xue, S. Qin
{"title":"Erb‐(IL10)2 ameliorates radiation‐induced skin injury through eliminate oxygen free radicals","authors":"Jiahe Xu, Jiaxing Zhu, Qi Zhao, J. Xue, S. Qin","doi":"10.1002/pro6.1193","DOIUrl":"https://doi.org/10.1002/pro6.1193","url":null,"abstract":"Radiation‐induced skin injury (RISI) remains a serious concern during radiotherapy. IL‐10 is considered as an immune suppressive cytokine by inhibiting the secretion of the proinflammatory cytokines in cells. The aim of this study was to evaluate the protective role of Erb (IL10) 2 against ionizing radiation.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45230439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive‐stage small cell lung cancer: Is prophylactic cranial irradiation necessary in the era of immunotherapy with MRI surveillance? 广泛期小细胞肺癌:在MRI监测的免疫治疗时代,预防性颅脑照射是否必要?
Precision Radiation Oncology Pub Date : 2023-06-01 DOI: 10.1002/pro6.1200
Yuanhu Yao, N. Yao, Zhaohui Qin, Ji Ma, Jiaying Lu, Li-qiang Cui, Wanxi Qu, Shiwang Yuan, Shaodong Tong, Na Li, Hao Li
{"title":"Extensive‐stage small cell lung cancer: Is prophylactic cranial irradiation necessary in the era of immunotherapy with MRI surveillance?","authors":"Yuanhu Yao, N. Yao, Zhaohui Qin, Ji Ma, Jiaying Lu, Li-qiang Cui, Wanxi Qu, Shiwang Yuan, Shaodong Tong, Na Li, Hao Li","doi":"10.1002/pro6.1200","DOIUrl":"https://doi.org/10.1002/pro6.1200","url":null,"abstract":"The role of prophylactic cranial irradiation (PCI) in treating extensive‐stage small‐cell lung cancer (ES‐SCLC) has been controversial. This study aimed to comprehensively analyze the efficacy of PCI for the treatment of ES‐SCLC under active brain magnetic resonance imaging (MRI) surveillance.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43371867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Skin metastasis in squamous cell cancer of cervix: A case report 癌症鳞状细胞皮肤转移1例报告
Precision Radiation Oncology Pub Date : 2023-06-01 DOI: 10.1002/pro6.1195
Xiujuan Zhao, Rui-hua Chen, Qi Zhou
{"title":"Skin metastasis in squamous cell cancer of cervix: A case report","authors":"Xiujuan Zhao, Rui-hua Chen, Qi Zhou","doi":"10.1002/pro6.1195","DOIUrl":"https://doi.org/10.1002/pro6.1195","url":null,"abstract":"Cervical cancer, the fourth most common cancer among females in the world, ranks the second in China. In advanced disease, metastases may be commonly present in the lungs, bones, liver and lymph nodes or elsewhere, but uncommon to the skin. In this report, a 63‐year‐old woman was diagnosed as stage IVB cervical squamous cell cancer in January 2021. The patient was scheduled for concurrent chemoradiotherapy; however, a metastatic lesion of skin was proved by biopsy during the process of treatment. She died 1 month after confirmed skin metastases. Cutaneous metastasis of cervical cancer may predict the mix of lymphatic and hematogenous metastasis and the rapid fatal termination.","PeriodicalId":32406,"journal":{"name":"Precision Radiation Oncology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47564860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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