Sara Fereshtian, M. Peeri, Hamid Agha Alinejad, M. Delfan
{"title":"Effect of 4 Weeks of High Intensity Interval Training with Curcumin Supplementation on COL-I, COL- II, SMAD3 Gene Expression in the Myocardium of Obese Male Rats with Type 2 Diabetes","authors":"Sara Fereshtian, M. Peeri, Hamid Agha Alinejad, M. Delfan","doi":"10.18502/ssu.v30i8.11012","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11012","url":null,"abstract":"Introduction: The aim of this study was investigating the effect of 4 weeks of high intensity interval training with curcumin supplement on the gene expression of collagen I, II and SMAD/3 in the myocardium of male obese rats with type 2 diabetes. \u0000Methods: In this experimental study, 35 male diabetic rats were divided in to 5 groups of seven; normal control, diabetic control, curcumin+diabetic, high intensity interval training, high intensity interval training+curcumin. Diabetes was induced by an intraperitoneal injection of streptozotocin with a dose of 60 mg/kg in all groups except the normal control group. Curcumin was gavage 200 mg/kg of body weight in all groups except normal control and diabetic control groups to determine the expression of COL-I, II and SMAD/3 genes, PCR-Real time method and group comparison were used by Two-way ANOVA test at alpha level of 0.05. \u0000Results: The decrease in COL-I gene expression in (S+HIIT (group compared to the (DC) (P<0.0001) and S+DC (P<0.0004) was significant, respectively. In high intensity interval training (HIIT) group, the decrease in COL-I gene expression was also significant compared to the diabetic control (DC) group (P=0.017).The decrease in COL-II gene expression in curcumin + high intensity interval training (S+HIIT) group compared to the (S+DC) (P=0.001) and diabetic control (DC) (P<0.0003) and in (HIIT) group was significant compared to the (DC) group (P=0.013) and (S+DC) (P=0.029).The decrease in SMAD/3 gene expression in (S+HIIT) group compared to the HIIT (P=0.008), (S+DC) (P<0.0002), (DC) groups (P<0.0006) and in the (HIIT) group was significant compared to the (NC) (P=0.010), (DC) (0.006) and (S+DC) groups (P=0.032). \u0000Conclusion: The results showed that, high intensity interval training reduced COL-I, COL-II and SMAD/3 genes and decreasingthe expression of SMAD/3 due to high intensity interval training with curcumin supplementation possibly can improve diabetic fibrosis in myocardial.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48860120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohsen Karimi, M. Gheini, Fatemeh Taleahmad, M. Roghani
{"title":"Effect of Trigonelline on Dendritic Morphology in the Hippocampus and Prefrontal Cortex in Streptozotocin-Induced Diabetic Rats","authors":"Mohsen Karimi, M. Gheini, Fatemeh Taleahmad, M. Roghani","doi":"10.18502/ssu.v30i8.11008","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11008","url":null,"abstract":"Introduction: Diabetes mellitus causes adverse changes in the neurological morphology of the hippocampus and prefrontal cortex of the brain by increasing oxidative stress. Trigonelline has antihyperglycemic effects and can inhibit oxidative stress. The aim of this study was to evaluate the protective effect of trigonelline on dendritic changes in hippocampal and prefrontal cortex neurons in diabetic rats. \u0000Methods: In this experimental study, 32 male Wistar rats in the weight range of 195-235 grams were randomly divided into 4 groups consisting of control, trigonelline-treated control, diabetic and trigonelline-treated diabetic. Oral trigonelline treatment at a dose of 50 mg/kg/day during 7 weeks was done. Diabetes induction was done by single dose injection of intraperitoneal streptozotocin at a dose of 60 mg/kg. Serum glucose and body weight were measured at the beginning and at weeks 4 and 8 after diabetes induction. For evaluation of hippocampal and prefrontal cortex neuronal dendrites, Golgi impregnation method was used. For statistical analysis, one-way ANOVA and Tukey post-tests in SPSS version 16 were used. P<0.05 was considered as a significant level. \u0000Results: Serum glucose level in the diabetic group treated with trigonelline significantly has been reduced compared with the diabetic group (p<0.01). The density of dendritic spines of prefrontal cortex and hippocampal neurons in the diabetic group significantly reduced compared to the control group (p<0.01). Moreover, in the diabetic group treated with trigonelline, dendritic spine density significantly increased compared to the diabetic group (p<0.05). \u0000Conclusion: Trigonelline is hypoglycemic and can prevent reduction of dendritic spines in the prefrontal cortex and the hippocampus of streptozotocin diabetic rats.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49123724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Study of Basil (Ocimum basilicum L) and its Mechanism of Action on Type 2 Diabetes","authors":"Melika Kheshti, Khojasteh Malekmohammad, Firouzeh Gholampour","doi":"10.18502/ssu.v30i8.11006","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11006","url":null,"abstract":"Introduction: Diabetes mellitus is a chronic metabolic disease with life threatening complications such as diabetic retinopathy, renal failure and cardiovascular disease. Metformin, Glibenclamide, Acarbose, Empagliflozin, Sitagliptin and Repaglinide are the most common drugs for reducing the blood glucose. The blood glucose-lowering drugs have side effects such as severe hypoglycemia, liver cell damage, lactic acidosis, permanent neurological defects, gastrointestinal disorders, headache, and dizziness. Hence, it is necessary to use safe and effective strategies for reducing blood glucose in the management of diabetes and related diseases. Therefore, in the recent years, medicinal plants have been used all over the world due to their wide therapeutic effects. Basil (O. basilicum) is one of the medicinal plants with anti-diabetic property. This article aimed to review of the Basil effects on the type 2 diabetes. \u0000Conclusion: O. basilicum has significant role in the control of diabetes through different mechanisms. These include: inhibition of glucose production in the liver, increasing glycogen synthesis, decreasing gluconeogenesis and glycogenolysis, stimulation of insulin secretion by the pancreas, and inhibition of α-glucosidase and α-amylase enzymes. Therefore, Basil and its biologically active compounds such as flavonoids, alkaloids and polyphenols act as potent anti-diabetic agents. \u0000 ","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43936373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Serum Levels of Adiponectin and Cortisol between Overweight/Obese and Normal Weight Men","authors":"M. Nezhadali","doi":"10.18502/ssu.v30i8.11007","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11007","url":null,"abstract":"Introduction: Obesity, results in a number of serious complications, such as type 2 diabetes, non-alcoholic fatty liver disease and metabolic syndrome. The levels of blood of adiponectin and cortisol have been associated with obesity. This study aimed to investigate the relationship of adiponectin and cortisol levels with obesity and biochemical parameters. \u0000Methods: This case-control study was conducted only on men, 80 participants with body mass index (BMI)≥25 considered as case group, and 100 participants with BMI<25 as control group in the Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences. Plasma levels of adiponectin and cortisol were measured through ELISA kit and other variables were determined by standard methods. Data were analyzed using SPSS software version 16. P-values <0.05 were considered as significant. \u0000Results: Our findings showed no significant difference in cortisol level between individuals with BMI≥25 and individuals with BMI<25. Obese men had significantly higher levels of triglycerides, systolic and diastolic blood pressure and lipid profiles whereas, adiponectin and high-density lipoprotein-cholesterol (HDL-C) levels were lower compared to the control group (p-value<0.05). In this study, an inverse correlation was observed between adiponectin and fasting blood glucose (FBS), and also BMI. It was found a positive correlation between cortisol and cholesterol and also FBS. \u0000Conclusion: The results show that there is no relationship between cortisol and obesity, but a negative correlation between adiponectin levels and obesity. \u0000 ","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44511096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effect of a Mixture of Native Iranian Probiotics on Biochemical Factors and Kidney Tissue of Male Rats Exposed to Cadmium Chloride","authors":"Shakiba Salar, Z. Keshtmand","doi":"10.18502/ssu.v30i8.11009","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11009","url":null,"abstract":"Introduction: Cadmium (Cd) is an environmental pollutant and chemical agent that destroys cell structure in various tissues. Probiotics are normal flora bacteria that if consumed adequately, will have health benefits in addition to nutritional benefits. The aim of this study was to investigate the effect of a mixture of native Iranian probiotics on biochemical factors and kidney tissue of male rats exposed to cadmium chloride. \u0000Methods: In this experimental study, 21 male Wistar rats were divided into 3 groups of 7: control, cadmium chloride recipient (3mg/kg) and cadmium chloride recipient (3mg /kg) + mixture of probiotics (CFU/mL109) were divided. Single-dose cadmium chloride was given to rats by intraperitoneal injection and probiotics by gavage for 30 days. At the end of the test, blood samples were taken directly from the heart to study serum creatinine and urea concentrations by autoanalyzer method and kidney tissue was used for microscopic studies of E&H staining. The data were evaluated using SPSS software version 16 and one-way ANOVA and Tukey test. \u0000Results: The results of Cadmium chloride significantly increased serum creatinine and urea concentrations compared to the control group (P<0.05) while in the group receiving probiotic mixture compared to the cadmium chloride group showed a significant decrease. Damage to kidney tissue was also shown compared to the control group. On the other hand, the structure of kidney tissue in the group treated with a mixture of probiotics compared to the group of cadmium chloride showed improvement. \u0000Conclusion: It is possible to use as a candidate a mixture of native Iranian probiotics (Lactobacillus rhamnosus, Lactobacillus casei and Lactobacillus holoticus) against cadmium chloride damage to the tissues of male rats.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43441515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Rezaeian, Hasan Ali Nejad, Zeinab Haj Ali Akbari, A. Taherifard, Mahdi Ali Nejad, Parinaz Sabaghi
{"title":"Relationship between Sleep Quality and Quality of Life of the Elderly with Cardiovascular Disease by Considering the Role of Physical Activity in Rafsanjan City in 2021","authors":"M. Rezaeian, Hasan Ali Nejad, Zeinab Haj Ali Akbari, A. Taherifard, Mahdi Ali Nejad, Parinaz Sabaghi","doi":"10.18502/ssu.v30i8.11010","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11010","url":null,"abstract":"Introduction: The quality of sleep and physical activity is specially important in the quality of life of the elderly. The aim of this study was to determine the relationship between sleep quality and quality of life of the elderly with cardiovascular disease referred to Ali Ebn Abi Taleb Hospital in Rafsanjan City in 2021. \u0000Methods: In this descriptive study, the participants of the study included all the cardiovascular elderly patients referred to Ali Ebn Abi Taleb Hospital in Rafsanjan City in the first 6 months of 2021. A total of 292 people were selected as the sample using purposive sampling method. Data collection tools included three standard questionnaires, including Baecke physical activity, Petersburg sleep quality and Ware and Sherbourne quality of life (SF-36). Independent t-test, one-way analysis of variance and chi-square test were used to analyze the data. The SPSS software version 16 used was for analyzing the data. \u0000Results: The results showed that with increasing physical activity, the quality of life also increases and with increasing the quality of sleep, the quality of life increased. There was also a significant correlation between psychological quality of life with physical activity (P<0.001 and r = 0.777) and sleep quality (P<0.001 and r = -0.804). \u0000Conclusion: According to the research findings, it is recommended to create a wide and healthy physical activity and healthy leisure time for the elderly and to develop counseling programs for the elderly. Therefore, the quality of life and sleep quality skills training should be provided.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44056662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of Culture-Positive Shigellosis Patients during Bloody Diarrhea Epidemics in Isfahan Province during 2015-2021","authors":"H. Hatami, M. Farsi, A. Hajari","doi":"10.18502/ssu.v30i8.11011","DOIUrl":"https://doi.org/10.18502/ssu.v30i8.11011","url":null,"abstract":"Introduction: As one of the diseases transmitted through water and food, shigellosis is one of the health problems in developing countries. This study was conducted in order to investigate the outbreaks of bloody diarrhea caused by Shigella in patients with positive cultures in Isfahan province during 2014-2016. \u0000Methods: This study was a cross-sectional descriptive-analytical study. Information of 280 infected patients with positive Shigella cultures based on demographic information, age, sex, place of residence, clinical symptoms, history of food consumption, and the date of illness and referral to medical centers were analyzed using SPSS16 software, checking percentages and frequencies, chi-square and t-tests were investigated. \u0000Results: The percentage of female patients of this study was 51.1% and male was 48.9% with a mean age of 25.53± 21.36; 27.1% of patients were housewives and 94.3% were Iranians. 97.1% of patients, in addition to positive cultures, red blood cells were also reported in microscopic examination of their stool samples. . 23.26% of patients had fever, 19.86% had nausea and 16.99% had obvious bloody diarrhea. 26.88% of patients had a history of consuming vegetables and 94.1% of them referred to medical centers in the first three days to receive medical services. Furthermore, 45.5% of these patients were hospitalized and 54.5% were treated as outpatients and finally 100% of patients recovered. \u0000Conclusion: Community education for food hygiene is one of the essential educational needs and also the development of vegetable preparation centers in the form of packaging and having a health code is one of the essential needs in terms of health and food security.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46242361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. H. Razavi, M. Barzegar, Fateme Abbasi, M. Ebrahimzadeh, Nasim Namiraian
{"title":"Evaluation of the Ability of Panoramic Radiography in the Determining the Morphology and Position of third Molar Roots","authors":"S. H. Razavi, M. Barzegar, Fateme Abbasi, M. Ebrahimzadeh, Nasim Namiraian","doi":"10.18502/ssu.v30i7.10748","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10748","url":null,"abstract":"Introduction: Most third molars eventually need to be extracted, and this tooth has the most varied and unpredictable root position of all teeth. Therefore, considering the importance of accurate diagnosis of the roots of molar teeth before surgery to reduce its surgical complications, the aim of this study was to evaluate the ability of panoramic radiography to diagnose the situation of roots of third molars. the relationship of the roots to each other and the angle of the crown to the root in panoramic and clinical radiographs, respectively, using Romexis viewer and digimizer software were investigated. \u0000Methods: In this cross-sectional-analytical study, 104 third molars of 93 patients referred for wisdom tooth extraction were examined clinically for the number of roots, the relationship of roots to each other and the angle of the crown to the root in panoramic radiography using Romexis Viewer software and clinically after providing photograph and measuring the angle using digimizer software. \u0000Results: In evaluating the roots of third molars, the accuracy of panoramic radiographic interpretation regarding the number of roots was 63.27% and in the presence or absence of root, adhesion was 55.89%. In addition, Pearson correlation analysis showed that there was a significant relationship between the reported angle in radiographic interpretation and the actual angle (r = 0.318 and P value = 0.001). \u0000Conclusion: Therefore, panoramic radiography is a valuable guide for third molar surgery. It is only necessary to consider its high error rate in terms of morphological details such as the number of roots and their relationship to each other.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47211266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Bagherian, A. Banaeifar, S. Arshadi, M. Azarbayjani
{"title":"Effect of Training Intensity on HIF-1a Gene Expression and Cardiac TG Content in Rats with Non-Alcoholic Fatty Liver Disease","authors":"M. Bagherian, A. Banaeifar, S. Arshadi, M. Azarbayjani","doi":"10.18502/ssu.v30i7.10753","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10753","url":null,"abstract":"Introduction: HIF-1a is an important regulator in response to hypoxia that affects various genes involved in energy metabolism. The aim of this study was to investigate the effect of exercise intensity on HIF-1a gene expression and cardiac TG content in rats with non-alcoholic fatty liver disease. \u0000Methods: The present study was performed experimentally on 40 male Wistar rats. Mice were randomly divided into 4 groups. The control groups, low-intensity endurance training and intense interval training, consumed high-fat food for 16 weeks, and then the two training groups participated in exercise for 8 weeks. Furthermore, sham group, which used standard food during this period, at the end of training, the expression level of HIF-1a and the amount of intra-tissue fat of the heart were measured in 4 groups. HIF-1a expression was assessed using real-time PCR and TG assay on an auto-analyzer. SPSS software version 16 and analysis of variance were used to analyze the data. \u0000Results: The results showed that there was a significant difference in the expression of HIF-1a gene between the control and the sham groups, HIIT and LIET groups (P=0.001). Moreover, there was a significant difference in triglyceride between HIIT and LIET groups compared to the sham and control groups, but no significant difference was observed between HIIT and LIET groups (P=0.0001). \u0000Conclusion: The results showed that intense intermittent exercise and low-intensity continuous exercise may reduce cardiac triglyceride content by decreasing HIF-1a expression and increasing fatty acid oxidation.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45842341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluating the Effect of First Skin to Skin Contact Father with Premature Infants Admitted to their Anxiety","authors":"K. Dehghani, Aliasghar Panabadi, N. Salmani","doi":"10.18502/ssu.v30i7.10751","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10751","url":null,"abstract":"Introduction: The birth of a premature baby shocks parents a lot. Although fathers also experience high levels of anxiety, they have received little attention and research. In order to focus on family care, this study was conducted to determine the effect of the first skin contact of fathers with premature infants hospitalized on their anxiety in the neonatal intensive care unit. \u0000Methods: This study was a randomized clinical trial with two experimental and control groups. 72 fathers of premature infants admitted to the neonatal intensive care unit of Shohada-e-Kargar Hospital were selected. In the experimental group, fathers made skin-to-skin contact with their infants for half an hour. In the control group, no intervention was performed. The level of anxiety in the experimental and control groups before and after the intervention was determined using the Spielberger Anxiety Questionnaire. The collected data were analyzed using t-test and Chi-square statistical tests in SPSS 16 software. \u0000Results: The results showed that before the intervention in the experimental group, the mean scores of trait and state anxiety were 54.28±16.26 and 50.36±14.66, respectively, these mean scores in the control group, were 59.81±14.48 and 58.86±15.41, respectively, which was not statistically significant. However, after the intervention, the mean scores of trait (47.92±10.1) and state anxiety (48.47±9.7) of the experimental group compared to the mean scores of trait (57.72±14.65) and state anxiety (62.47±14.16) of the control group decreased, which showed a statistically significant difference (p<0/05). \u0000Conclusion: According to the results, making the first skin contact reduces the level of anxiety in fathers of premature infants.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47070076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}