Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd最新文献

{"title":"A Review of Laboratory Methods for Measuring Oxidative Stress","authors":"Fatemerh Asadian, M. Takhshid","doi":"10.18502/ssu.v30i7.10747","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10747","url":null,"abstract":"Introduction: Antioxidant defense system, including enzymatic and non-enzymatic antioxidants, protects cells from oxidative damage by neutralizing oxidant compounds. Increasing the production of oxidant species and decrease activity of antioxidant system causes oxidative stress. The role of oxidative stress in the pathogenesis of human diseases and strengthening of human antioxidant defense system in preventing and ameliorating of diseases have been shown in numerous studies. Therefore, identifying reliable oxidative stress markers for evaluating the beneficial effects of antioxidants in human diseases has been the focus of many studies over the past decades. Measuring free radicals and active species by flow cytometry, determining the total antioxidant capacity of body fluids, measuring the oxidation products of macromolecules, determining the activity of antioxidant enzymes, and changing the expression of genes related to the antioxidant system are among these methods. This review discussed the major advantages and limitations of these methods. \u0000Conclusion: Due to limitations and potential confounding factors of the current markers of oxidative stress, an appropriate experimental protocol should be used for each study and caution should be taken in the interpretation of results. Furthermore, more than one method should be used to overcome the limitations of each marker.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48475950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Frequency Pattern of Risk Factors for Decreased Bone Mineral Density in Postmenopausal Women Referred to the Bone Mineral Density Assessment Center of Al-Zahra Hospital in Isfahan during Years 2018 and 2019","authors":"Bahram Pakzad, Golareh Parsaei, J. Karimi","doi":"10.18502/ssu.v30i7.10749","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10749","url":null,"abstract":"Introduction: Osteoporosis is a systemic skeletal disease in which the internal structure and ability of bone to repair its daily damage is impaired. Menopause is a vital period that affects bone health, causing rapid loss of bone mass, which in turn increases the risk of fractures in postmenopausal women. The present study was performed to evaluate the frequency pattern of risk factors for decreased bone mineral density in postmenopausal women referred to the bone mineral density assessment center of Al-Zahra Hospital in Isfahan in years 2018 and 2020. \u0000Methods: Among postmenopausal women referred to the Bone Density Assessment Center of Al-Zahra Hospital from March 2018 to March 2020, 384 people were included in the study using simple random sampling method. Patients’ information was extracted from their files. Data were analyzed using SPSS 16 software. \u0000Results: In this study, the prevalence of osteopenia and osteoporosis in postmenopausal women was 46.1% and 41.1%, respectively. The results showed that with increasing age, diabetes, use of corticosteroids, autoimmune disease and a previous history of femoral fracture, the chance of osteopenia and osteoporosis in postmenopausal women increased sharply. Among the known risk factors for decreased bone density, diabetes was the most common in postmenopausal women and followed by corticosteroids consumption. \u0000Conclusion: This study showed that 87.2% of postmenopausal women had decreased bone mineral density. Osteoporosis as one of the main problems of women's health requires proper planning and preventive measures.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47555957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation the Level of Awareness of Patients Referring to Imaging Centers of Mashhad University of Medical Sciences Hospitals about the Ionizing Radiation Risks","authors":"Shabnam Olumi, Amirhossein Fathabadi, H. Azimian, S. Mostafapour, S. Khademi","doi":"10.18502/ssu.v30i7.10752","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10752","url":null,"abstract":"Introduction: The undeniable role of medical imaging in the diagnosis and treatment of diseases shows the importance of protection against ionizing radiation used in these methods. Therefore, the aim of the present study is investigating the necessity of increasing patients' awareness of ionizing radiation in minimizing the dose received. \u0000Methods: The present study was a cross-sectional analytical study with 159 research-made questionnaires, including demographic information and questions about the level of awareness of patients regarding the dangers of ionizing radiation and protection against these radiations, were completed by the patients referring to the radiology departments of Mashhad University of Medical Sciences in 2019. Data analysis was done using t-test and one-way analysis of variance under SPSS 16 software. \u0000Results: The mean knowledge score of the patients was 35.36% ± 26.07%. Moreover, 91/1% of them stated in their answers that they would like physicians to explain the benefits and risks of these radiations, while only 35.2% of patients were informed by their physicians. \u0000Conclusion: According to the results of the completed questionnaires, a low percentage of the patients answered the specialized questions correctly, and according to the individuals' statements, 91/2% stated that they would like to receive information in this regard. Therefore, the need to provide appropriate training to the patients in this field, through the preparation of training brochures, and attracting staff cooperation, to inform patients referring to radiology departments about the risks should be a priority.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45794558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of Vasovagal Syncope based on Body Vigilance and Alexithymia Variables","authors":"Somayeh Ramesh, M. Besharat, H. Soltanian-Zadeh, R. Rostami, A. Vasheghani Farahani, H. Farahani","doi":"10.18502/ssu.v30i7.10754","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10754","url":null,"abstract":"Introduction: Vasovagal syncope is the most common type of syncope and recurrent syncope attacks can have a profound effect on the patients' quality of life. The aim of this study was to predict vasovagal syncope based on the variables of body vigilance and alexithymia. \u0000Methods: The present study was a case-control study. The statistical population of the present study included the patients with vasovagal syncope referred to Tehran Heart Center in the year of 1400. Fifty patients with vasovagal syncope and 54 healthy individuals were selected by purposive sampling. Data collection tools included the Body Vigilance Scale and Toronto Alexithymia Scale. Data analysis was performed by logistic regression analysis and using SPSS software version 16 at the level of 0.05. \u0000Results: The results of the Hosmer-Lemeshow Test (P-value = 0.255, χ2 = 3.07) showed good model fit. According to the results of logistic regression test, the coefficient estimate for the alexithymia -0.053 and the body vigilance was -0.017. \u0000Conclusion: Based on the results, in the patients with vasovagal syncope, by designing measures based on reducing body vigilance and alexithymia, they can be helped to improve and reduce syncope episode.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42620943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of CXCL12 and CXCR4 Genes Polymorphism with Proliferative Diabetic Retinopathy in Diabetic Patients","authors":"S. Gharibi, S. Aghaei, Ensieh Shahvazian, M. Mahmoodi, M. H. Sahami-Fard, Parisa Kolahdouz, E. Farashahi Yazd","doi":"10.18502/ssu.v30i7.10750","DOIUrl":"https://doi.org/10.18502/ssu.v30i7.10750","url":null,"abstract":"Introduction: Patients with diabetes are prone to develop complications related to the retina. So far, several genes have been reported in connection with the progression of retinopathy, and a group of these genes is genes involved in angiogenesis. CXCL12 and CXCR4 genes are among the most important genes in this path, which have been less studied and investigated. The aim of this study was to determine the relationship between polymorphism of CXCL12 (rs1801157) and CXCR4 (rs2228014) genes and the risk of proliferative diabetic retinopathy in the population of Yazd City. \u0000Methods: In the present case-control study, rs2228014 and rs1801157 polymorphisms were investigated among 103 patients with diabetes in two groups, case and control. In this study, the control group included 49 diabetic patients who did not show retinopathy complications, and the case group consisted of 54 diabetic patients with proliferative retinopathy complications. The Genotyping of rs2228014 polymorphism was examined by ARMS-PCR method and rs1801157 variant by RFLP-PCR technique. The statistical analysis of data was conducted using SPSS software version 16 and chi-square test. \u0000Results: Our results represented no association among the rs1801157 and rs2228014 polymorphisms and the risk of proliferative diabetic retinopathy (P>0.05). \u0000Conclusion: This study did not confirm association of the rs1801157 and rs2228014 polymorphisms with proliferative diabetic retinopathy and further studies are required to investigate the correlation of polymorphisms of interest with PDR.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45416839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Prosthetic Procedural Skills in Senior Dental Students Using the Self-Assessment Method","authors":"Mahnaz Hatami, F. Mahdavi, Farnoosh Najafi","doi":"10.18502/ssu.v30i6.10352","DOIUrl":"https://doi.org/10.18502/ssu.v30i6.10352","url":null,"abstract":"Introduction: Student self-assessment is one of the methods of assessing procedural skills that complements existing assessments in dentistry. This study was designed to evaluate prosthetic procedural skills in senior dental students using the self-assessment method. \u0000Methods: In this descriptive cross-sectional study, the level of practical skills of 127 senior dental students of Yazd, Esfahan and Kashan faculties were selected and their procedural skills were assessed by a researcher-made questionnaire. The validity of the questionnaire was confirmed through content validity and its reliability through Cronbach's alpha test (r=0.8).To analyze the data, SPSS 16 statistical software and t-test, Chi-square, ANOVA and non-parametric statistical tests were used at the significance level of 0.05. \u0000Results: Dental students with a mean age of (25.15 ±1.74) were included in this study. The mean of procedural skills score was 115.51 ±11.78 out of 175, which was at an average level. Procedural skills score was not significantly associated with age, gender, marriage, entrance exam rank, university, the level of anxiety during prosthetic application (P>0.05), but the mean score of procedural skills in complete and partial prosthesis was significantly higher in people who interested in prosthesis (P˂ 0.05). \u0000Conclusion: Due to the limitations of the present study, the procedural skills levels in dental prosthesis of senior dental students of Yazd, Esfahan and Kashan faculties was evaluated at an average level. Revision of curriculum- based teaching methods in clinical departments and implementation of new methods for evaluating procedural skills such as DOPS test can be effective in improving the level of clinical skills of learners. \u0000 ","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43954832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of Growth Process of Infants in Healthy and Gestational Diabetes Mothers in Rafsanjan City in 2017","authors":"F. Jalali, Z. Kamiab, Shayan Pourghazi, Gholamreza Bazmandegan","doi":"10.18502/ssu.v30i6.10349","DOIUrl":"https://doi.org/10.18502/ssu.v30i6.10349","url":null,"abstract":"Introduction: Gestational diabetes (GDM) can affect neonatal developmental indicators. The aim of this study was to evaluate and compare the growth process of infants less than 2 years of age with GDM and healthy mothers in Rafsanjan City. \u0000Methods: This cross-sectional study was performed on 208 neonates under 2 years of age from healthy mothers (104 neonates) and GDM mothers (104 neonates) in Rafsanjan City in 2017. Weight, height and head circumference were measured at birth, 6, 12 and 18 months. Fasting serum glucose above 126 mg/dl after 8 hours of fasting was considered as GDM. Data analysis was performed using SPSS 16 software and independent t-test, Chi-square and repeated measures analysis. Significant level was considered 0.05. \u0000Results: The mean age of GDM mothers was 31.8±5.3 and healthy mothers were 29.2±5.5 years. Cesarean delivery was reported in 73.1% of mothers with GDM and in 57.7% of healthy mothers (P = 0.020). Changes in weight, height and head circumference in the two groups at birth, 6 months, 12 months and 18 months after birth had an increasing process that was higher in infants of mothers with GDM (P <0.001). \u0000Conclusion: The process of weight, height and head circumference changes in infants born to mothers with GDM was higher.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44401682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Eight Weeks of Endurance Training in Light and Dark Phases of Circadian Rhythm on the Oxidative Stress Index in Pancreas of Diabetic Mice","authors":"Maryam Janbozorgi, Abassali Gaini, S. Choobineh, M. Tabandeh","doi":"10.18502/ssu.v30i6.10351","DOIUrl":"https://doi.org/10.18502/ssu.v30i6.10351","url":null,"abstract":"Introduction: Chronic hyperglycemia is associated with an increase in cellular damage due to oxidative stress in pancreatic tissue. The effect of exercise in different phases of the circadian cycle on protecting pancreatic tissue from oxidative stress in diabetic patients is unknown. The aim of this study was to investigate the effect of eight weeks of endurance training in light and dark phases of circadian rhythm on the oxidative stress index in pancreas of diabetic mice. \u0000Methods: In this study, 18 mice from the Naval Medical Research Institute  (26.3±3.22 gr) were selected and after inducing diabetes through high-fat food and Streptozotocin injection (20 mg/kg), randomly divided into 6 groups: light phase healthy control, dark phase healthy control, light phase diabetic control, dark phase diabetic control, light phase diabetic training and dark phase diabetic training. The endurance training protocol (50-60 %Vmax) was performed 5 d/w for 8 weeks. After anesthesia, blood samples and pancreatic tissues were removed. Insulin resistance markers, oxidative stress index and expression of Brain and Muscle ARNT-Like1 protein expression were measured in pancreas of diabetic rats. Data were analyzed by one way analysis of variance at the significance level of p <0.05. \u0000Results: The eight weeks of endurance training significantly decreased insulin resistance markers (p= 0.005), oxidative stress index (p ˂0.05) and significantly increased the Bmal1 protein expression (p = 0.009). The mean values of all variables showed significant differences between light and dark phases. \u0000Conclusion: Endurance training may improve insulin sensitivity and oxidant damage in diabetic conditions by increasing the function of the antioxidant system and the expression of Circadian regulation proteins. Activity in the dark phase causes further increases the metabolism of cells. As a result, performing these types of exercises in the dark phase is recommended to these patients as a new treatment strategy.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43166644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corona Virus Prevention and the Role of Marketing Mix in it","authors":"G. Zarei, Adeleh Dehghani Ghahnavieh","doi":"10.18502/ssu.v30i6.10347","DOIUrl":"https://doi.org/10.18502/ssu.v30i6.10347","url":null,"abstract":"Introduction: Considering the widespread and irreversible effects that Corona has had on health, economy and society, it is the duty of marketers to prevent Coronavirus through effective marketing and promote preventive behaviors. The purpose of this study was to present a model of effective marketing mix on Coronavirus prevention. \u0000Methods: The present study was a descriptive-survey and cross-sectional. The population of this study was social media users. The sample size was 177 people. The data collection tool was a questionnaire. In this study, content validity and construct validity were evaluated and the reliability of the questionnaire was obtained by calculating Cronbach's alpha coefficients and combined reliability. Structural equation modeling and SPSS16 and Smart Pls2.0 software were used to analyze the data. \u0000Results: The results show that advertising (t=2/731 and path coefficient 0/236), product (t=4/458 and path coefficient 0/473) and distribution (t=3/050 and path coefficient 0/320) on change Behavior has a positive and significant effect, and advertising has a positive and significant effect on Coronavirus awareness (t=6/658 and path coefficient 0/674) and Coronavirus awareness of behavior change (t=2/522 and path coefficient 0/215), as well as behavior change It also has a positive and significant effect on preventive behaviors (t=5/104 and path coefficient 0/716). But the effect of price on behavior change (t=1/664 and path coefficient -0/196) was not confirmed. \u0000Conclusion: Social media and marketing mix is ​​an effective factor in changing preventive behaviors and behaviors in Corona that needs to be considered by health officials and officials to use preventive behaviors with appropriate use of social media and marketing mix.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46176562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and Evaluation of Collagen from the Fish (Thunnus Tonggol) Skin: A Biological Material for Medical Tissue Engineering","authors":"M. Samiei, S. Jamili, H. Nikukar, V. Razban","doi":"10.18502/ssu.v30i6.10348","DOIUrl":"https://doi.org/10.18502/ssu.v30i6.10348","url":null,"abstract":"Introduction: Collagen bears many applications in pharmacy and medicine, health and cosmetic products as well as food industry. In recent years, much attention has been paid to separation of collagen from marine organisms arising from the fact that its use in the diet is not restricted and triggers no risk of contagious diseases as well as religious restrictions. Moreover, fish collagen is unique in terms of its extremely high solubility in dilute acid on a scale with mammalian and chicken collagen. The purpose of this study was to investigate the isolation and evaluation of collagen from fish skin (Thunnus tonggol) as a biological material for medical tissue engineering. \u0000Methods: Acid-soluble collagen (ASC) was isolated from fish skin using acetic acid. The Thunnus tonggol skin collagen was extracted by acid and base methods and evaluated by PAGE-SDS, FTIR and UV spectrophotography and amino acid composition analysis. \u0000Results: The results, predicated on SDS-PAGE and amino acid compositions, demonstrated that the fish skin collagen is of type I. Fourier transform infrared analysis also revealed helical compositions of both collagens. UV spectrophotometry in the Thunnus tonggol skin collagen indicated a maximum absorption of 235 nm. The amount of collagen extracted from the Thunnus tonggol skin turned out to be 17.3%. Through analysis of collagen amino acid extracted from the mentioned fish, glycine was predominant. The growth and proliferation of human fibroblast cells on the collagen extracted from the Thunnus tonggol skin was more than control. \u0000Conclusion: The results revealed that the fish collagen is an accessible and advantageous material for medical usage and tissue engineering.","PeriodicalId":32076,"journal":{"name":"Majallahi Danishgahi ''Ulumi Pizishkii Shahid Saduqi Yazd","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49283346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}