Scientific Dental Journal最新文献

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Peppermint flavor oil in fluoride varnishes enhances fluoride release 含氟清漆中的薄荷香油可以促进氟化物的释放
Scientific Dental Journal Pub Date : 2021-09-01 DOI: 10.4103/sdj.sdj_78_21
Y. Eriwati, Dhea Putriani, Karen Geraldine, H. Hermansyah
{"title":"Peppermint flavor oil in fluoride varnishes enhances fluoride release","authors":"Y. Eriwati, Dhea Putriani, Karen Geraldine, H. Hermansyah","doi":"10.4103/sdj.sdj_78_21","DOIUrl":"https://doi.org/10.4103/sdj.sdj_78_21","url":null,"abstract":"Background: Fluoride varnish (FV) is a common dental health treatment for the prevention of early childhood caries. Application of FV with a flavoring agent promotes comfort and acceptance by patients, especially children, and facilitates an effective treatment time. Objective: Flavored FV with a pleasant flavor should allow a faster treatment time, especially with children. The aim of this research was to study basic FV formulations containing different flavors of essential oils (LorAnn) and variations in the concentrations of flavor oils to determine the optimum formulation to enhance the in vitro fluoride release time. Methods: The independent variables were the flavors (apple, melon, and peppermint) and the concentrations (1, 1.5, 2, or 2.5%) of the flavor that gave the best fluoride release (peppermint). The amounts of fluoride ions released in 6 h into deionized water were assessed at 37°C using an ion-selective electrode with the addition of fluoride total ionic strength adjustment buffer solution to strengthen the ion reading. The cumulative ion release was analyzed for normality and equality of variance, and the means were compared using a general linear model test and Statistical Package for Social Sciences version 23.0 software. The significance level was set at α = 0.05. Results: At the same concentration of 2% for the apple, melon, and peppermint flavors, the peppermint formulation gave the best fluoride release, at 173.22 mg/L. A peppermint oil concentration of 2.5% showed the highest fluoride ion release, at 178.95 mg/L. Conclusions: The addition of peppermint flavor oil at a concentration range of 1—2.5% revealed an increasing release of fluoride ions with an increasing peppermint oil concentration. Further investigations are still needed using artificial saliva to replicate actual conditions in the oral cavity.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"133 - 137"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44549353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Challenges in the management of oral manifestations in a patient with limited systemic sclerosis 局限性系统性硬化症患者口腔表现管理的挑战
Scientific Dental Journal Pub Date : 2021-09-01 DOI: 10.4103/sdj.sdj_93_21
Y. Lefaan, Riani Setiadhi
{"title":"Challenges in the management of oral manifestations in a patient with limited systemic sclerosis","authors":"Y. Lefaan, Riani Setiadhi","doi":"10.4103/sdj.sdj_93_21","DOIUrl":"https://doi.org/10.4103/sdj.sdj_93_21","url":null,"abstract":"Background: Limited systemic sclerosis (SSc), or scleroderma, is characterized by widespread vasculopathy, excessive multiorgan fibrosis, and autoantibody. The early stages of SSc are challenging to diagnose because of their similarity to other autoimmune conditions. Inappropriate SSc treatment can increase the risk of disability, morbidity, and mortality. Different pathogenesis pathways incur various manifestations in the skin and the oral cavity. In this scenario, dentists play an essential role in managing oral SSc manifestations. Proper oral examination, diagnosis, and therapy help to increase the confidence and patient’s quality of life. Case Report: A 24-year-old female patient with SSc was referred from the Internal Medicine Department to the Oral Medicine Department because of lip soreness for 2 weeks, resulting in difficulty eating and opening the mouth. A complete anamnesis and clinical examination were done. The patient was diagnosed with an oral ulcer caused by SSc, cheilitis exfoliative, drug-induced pigmentation, xerostomia, and acute pseudomembranous candidiasis. The oral lesion in this patient was concluded as an oral ulcer caused by SSc because the patient had already stopped using methotrexate for 2 weeks before the ulceration appeared. The oral treatment included sodium chloride (NaCl 0.9%), vaseline album, hyaluronic acid mouthwash, and nystatin. Oral lesions had a significant improvement after 3 days of treatment. Conclusion: The SSc manifestation that appeared on the oral cavity of the patient as microstomia, tongue stiffness, and oral ulcer resulted in inadequate clinical examination, and diagnosis. Treatments for this oral SSc were challenging.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"148 - 154"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44200842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anterior tooth trauma among schoolchildren aged 10—19 years in Mewat district, India 印度Mewat区10-19岁学童的前牙外伤
Scientific Dental Journal Pub Date : 2021-09-01 DOI: 10.4103/sdj.sdj_90_21
Amita Sharma, Saurabh Sharma, Sonam Sharma, Rachit Sharma
{"title":"Anterior tooth trauma among schoolchildren aged 10—19 years in Mewat district, India","authors":"Amita Sharma, Saurabh Sharma, Sonam Sharma, Rachit Sharma","doi":"10.4103/sdj.sdj_90_21","DOIUrl":"https://doi.org/10.4103/sdj.sdj_90_21","url":null,"abstract":"Background: Dental trauma is relatively common, with its incidence and prevalence varying not only within countries and states but also within different socioeconomic groups. A primary goal in oral health care is to prevent dental trauma. Objectives: The aim of the present study was to determine the prevalence of anterior tooth trauma (ATT) and to analyze factors associated with ATT among schoolchildren aged 10—19 years in Mewat district, an underdeveloped and underprivileged area in Haryana state, India. Methods: A cross-sectional study was conducted among 3043 schoolchildren residing in Mewat district. They were divided into the following age groups: 10—13, 14—16, and 17—19 years. Dental injuries to anterior teeth were recorded according to Ellis and Davey’s classification. Data were collected using a specifically designed questionnaire. The data were analyzed using IBM Statistical Package for Social Sciences for Windows (version 20.0). Categorical variables are presented as proportions (%), and Pearson’s χ2 test was used to analyze these variables. Tests were conducted at the significance level of 5%. Results: Of the 3043 schoolchildren (males, n = 2178; females, n = 865) examined in the study, 362 schoolchildren had experienced dental trauma, giving a prevalence rate of 11.89%. Males were more prone to ATT (13.36%), and an Ellis Class I fracture was the most frequent type of ATT (78%). The most common causes of ATT were falls (49.44%), followed by road traffic accidents. In addition, children with partial lip coverage and an overjet of more than 3 mm had an increased risk of ATT. Conclusion: The prevalence of ATT among schoolchildren in Mewat district was 11.89%, and the major etiological factor was a fall. There is an increased need for awareness of dental trauma in school-aged children.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"110 - 114"},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44791001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of gingival health status and salivary magnesium levels in smokers and nonsmokers 吸烟者和非吸烟者牙龈健康状况和唾液镁水平的比较
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_72_21
T. Wijaya, A. Susanto, Ina Hendiani
{"title":"Comparison of gingival health status and salivary magnesium levels in smokers and nonsmokers","authors":"T. Wijaya, A. Susanto, Ina Hendiani","doi":"10.4103/SDJ.SDJ_72_21","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_72_21","url":null,"abstract":"Background: Smoking is considered a major risk factor for the development and progression of periodontal diseases. The content of cigarettes can affect the composition of saliva, such as the levels of magnesium, calcium, and phosphate. Objectives: The purpose of this study is to compare gingival health status and salivary magnesium levels in smokers and nonsmokers. Materials and Methods: This research is a descriptive study based on a cross-sectional approach. Forty-two subjects participated in the study which was divided into two groups: smokers and nonsmokers. A purposive sampling technique was used, and a questionnaire was disseminated to collect data on age, gender, number of cigarettes smoked per day, duration of smoking, and types of cigarettes consumed. Oral health status was measured using the Löe and Silness gingival index. Saliva was collected using the spitting method, and salivary magnesium levels were measured by atomic absorption spectrometry. The data analysis was performed using the independent sample t-test and the Mann–Whitney test. Results: The gingival index scores for the smokers and nonsmokers were 0.49±0.195 and 0.26±0.207, respectively. There was a significant difference between smokers and nonsmokers gingival index (P = 0.001). The salivary magnesium levels in the smokers and nonsmokers were 54.43±17.37 and 51.29±15.97 µg/dL, respectively. There was no significant difference in the levels of magnesium saliva between the smokers and nonsmokers (P = 0.428). Conclusion: The findings of this study indicate that the gingival index in smokers is higher than that in nonsmokers. However, the results showed no difference in salivary magnesium levels between the smokers and nonsmokers in this study.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"79 - 83"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47129339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Management of temporomandibular joint disorders using acupuncture: A case report 针灸治疗颞下颌关节紊乱1例
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_70_21
Ahila Singaravel Chidembaranathan
{"title":"Management of temporomandibular joint disorders using acupuncture: A case report","authors":"Ahila Singaravel Chidembaranathan","doi":"10.4103/SDJ.SDJ_70_21","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_70_21","url":null,"abstract":"Background: Temporomandibular joint disorder (TMD) is a term for disease of the TMJ and the muscles attached to it. The symptoms and signs of TMD are clicking, crepitation, headache, and pain in and around the TMJ. Management of TMD includes dental approaches (e.g., splints, bite plates, and jaw exercises) and surgical approaches. Acupuncture is a Chinese medicine that consists of insertion of small solid stainless-steel needles into many acupoints on the body to improve health and relieve pain in the surrounding areas. Case Report: A 34-year-old male patient reported with severe pain in the right and left TMJ region and difficulty in opening of his mouth for the past 6 months. Extra-oral examination revealed tenderness on both sides of the face, deviation of the mouth toward the right side, the mouth opening was two finger breadths, and mild early-opening click. Intra-oral examination revealed the presence of 28 teeth. Orthopantogram did not show any changes in the condyle and articular eminence. The patient was initially treated with palliative therapy and then treated with acupuncture. Conclusion: Acupuncture is an alternative mode of treatment for persons with muscular TMD.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"97 - 99"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41854425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison between nanohybrid filler and submicron composite resin shade on color changes after polymerization 纳米杂化填料与亚微米复合树脂聚合后色度变化的比较
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_69_21
Reynald Irawan, A. Dwisaptarini, Elline Istanto, J. Sudiono
{"title":"Comparison between nanohybrid filler and submicron composite resin shade on color changes after polymerization","authors":"Reynald Irawan, A. Dwisaptarini, Elline Istanto, J. Sudiono","doi":"10.4103/SDJ.SDJ_69_21","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_69_21","url":null,"abstract":"Background: Initial color determination of composite resins before polymerization is crucial to achieve an esthetic result that mimics the original tooth color. A filler particle size and composition affect the color change of the composite resin after polymerization despite the improvement in the chemical composition and filler of the composite resin. Objective: The effects of nanohybrid filler and submicron composite resin shade on color changes after polymerization were determined. Methods: Disc-shaped composite resin samples (diameter and thickness of 12 mm and 2 mm, respectively) were categorized into six groups, with each group containing 10 plates, according to the shade and type of filler (nanohybrid UD1, UD2, UD3; submicron OA1, OA2, OA3). Digital photographs were taken before and after polymerization. The changes in color (ΔEFNx01ab values) were determined using software via eLABor_aid. Result: Only the Micerium EHRi UD1 composite resin group exhibited ΔEFNx01ab < 3.3. The independent t-test revealed significant differences in the ΔEFNx01ab (P < 0.05) between the nanohybrid and submicron composite resins in all shade groups (A1, A2, and A3). One-way analysis of variance revealed significant differences in ΔEFNx01ab (P < 0.05) among A1, A2, and A3 between the nanohybrid and submicron composite resin groups. Tukey’s post hoc test revealed significant differences in ΔEFNx01ab (P < 0.05) for the Micerium EHRi UD1 group compared with those of the UD2 and UD3 groups, as well as in the case of the Tokuyama Palfique OA1 group compared with those of the OA2 and OA3 groups. Conclusion: Nanohybrid filler and submicron composite resin shade affected color changes after polymerization. Compared to the darker color groups, brighter shades (UD1 and OA1) exhibited a lower-intensity color change.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"74 - 78"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43522187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Differences in Preparation Results of Two Reciprocal Ni-Ti Files with and Without Glide Path to the Changes on Root Canal Curvature 两种Ni-Ti锉预备结果对根管曲率变化的影响
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_75_21
Christian Susantio, Wiena Widyastuti, Anastasia Prahasti, R. Amtha
{"title":"Differences in Preparation Results of Two Reciprocal Ni-Ti Files with and Without Glide Path to the Changes on Root Canal Curvature","authors":"Christian Susantio, Wiena Widyastuti, Anastasia Prahasti, R. Amtha","doi":"10.4103/SDJ.SDJ_75_21","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_75_21","url":null,"abstract":"Background: Maintaining the anatomy of the root canal is crucial in root canal treatment. The super-elastic property of the nickel-titanium (Ni-Ti) file system provides advantages in preparation of curved root canals, as it can reduce the force on the root canal wall, increase centering ability, and reduce iatrogenic errors. Objective: The aim of this article is to determine the differences in preparation results of two reciprocal Ni-Ti files with and without glide path to the changes of root canal curvature. Materials and Methods: Twenty pieces of endodontic blocks (ISO# 15, 16 mm, 2% tapered) were divided into four randomly assigned groups. Group 1 (without glide path) and Group 2 (with glide path) were prepared with Wave One Gold (WOG). Group 3 (without glide path) and Group 4 (with glide path) were prepared with Reciproc Blue (RB). Each subject was explored using K-file #10. Glide path was prepared with ProGlider (PG) #16. Digital images of before and after the root canal preparations were taken using a digital camera with the same angle and distance settings. The before and after photos were superimposed on each other, and the transportation at the inner and outer root canal walls in the coronal curvature, apical curvature, and apical end points was measured with software. Results: No significant difference was found between changes in the coronal curvature using WOG and RB, with and without glide path (P > 0.05). The same result was observed between WOG and RB groups with glide path at each measurement point. Significant differences were found between changes in apical curvature and apical point in the inner wall using WOG and RB without glide path (P < 0.05). Conclusion: There were differences in root canal curvature prepared using WOG and RB on the apical region when prepared without glide path, but no differences were found when prepared with glide path at each point measurement.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"84 - 90"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43342793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Determination of the Fluoride Content of Malaysian Commercial Teas 马来西亚商业茶中氟化物含量的测定
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_56_20
Y. Ardini, Z. Asri, M. Azhar, W. Lestari, Anisa Kusumawardani, M. Haris
{"title":"Determination of the Fluoride Content of Malaysian Commercial Teas","authors":"Y. Ardini, Z. Asri, M. Azhar, W. Lestari, Anisa Kusumawardani, M. Haris","doi":"10.4103/SDJ.SDJ_56_20","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_56_20","url":null,"abstract":"Background: Tea ranks first as the most-enjoyed beverage worldwide. Nevertheless, tea is rich in fluoride due to its uptake and storage from the soil by tea plants. Moreover, limited information is available regarding the fluoride content of Malaysian teas. Objective: This study aims to quantify the amount of fluoride present in teas available in the Malaysian market. Methods: An exploratory research was conducted on commercially available infusion teas from Peninsular Malaysia between November 2016 and December 2017. The fluoride content of 106 tea samples from three groups, viz., black, green, and other tea types, respectively, was measured using ultraviolet–visible spectrophotometry. The results were analyzed by one-way analysis of variance and independent t-test. Results: All of the tea leaf samples contained fluoride content between 0.01 and 1.08 mg/L. Black, green, and red tea exhibited significantly different contents of fluoride (P = 0.028). Conclusion: Significant amounts of fluoride were present in teas found in Malaysian markets. Our study provides Malaysian consumers key information regarding the amount of fluoride present in their teas.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"68 - 73"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48517940","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Association Between Parenting Styles and Feeding Styles on Early Childhood Caries 父母教养方式与喂养方式对幼儿龋齿的影响
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_52_20
Nirmala Sari, Rosa Amalia, A. Supartinah
{"title":"The Association Between Parenting Styles and Feeding Styles on Early Childhood Caries","authors":"Nirmala Sari, Rosa Amalia, A. Supartinah","doi":"10.4103/SDJ.SDJ_52_20","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_52_20","url":null,"abstract":"Background: A parenting style (authoritarian, authoritative, and permissive) refers to a set of activities that parents perform to raise a child. A certain feeding style is influenced by a parenting style. The high intake of foods containing sugar without parental control can increase the incidence of early childhood caries (ECC). Objective: The Objective of this article is to analyze the association of parenting styles and feeding styles on the occurrence of ECC among children aged 3–5. Methods: The research was an analytical cross-sectional study. Data were collected from 105 pairs of mothers and children, selected through the purposive sampling technique in Yogyakarta. Type of parenting and feeding styles was obtained through questionnaires given to mothers, whereas intra-oral examination was used to detect the ECC in children using the decay-missing-filling-teeth (dmf-t) index. Data were collected and analyzed using multinominal logistic regression with a statistical significance at P < 0.05. Results: The prevalence of ECC and dmf-t among children with permissive parents was highest (63.84%; 7.51+5.97) when compared with those with authoritarian parents (26.21%; 3.09+4.23). Those with authoritative parents was lowest (9.95%; 1.17+1.65). Authoritative parenting is associated with less consumption of cariogenic foods and low occurrence of ECC (P < 0.05). Conclusion: Parenting styles have a direct association with feeding styles and ECC. Children with authoritative parents have a highest benefit on lowest risk of ECC when compared with other counterparts.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"63 - 67"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43842560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Estrogen-deficiency Effect on the Composition of Dental Enamel: A Pilot Study 雌激素缺乏对牙釉质成分影响的初步研究
Scientific Dental Journal Pub Date : 2021-05-01 DOI: 10.4103/SDJ.SDJ_61_20
G. Fernandes, E. Küchler, M. Omori, G. Marañón‐Vásquez, L. Teixeira, J. León, C. Lopes, F. Baratto-Filho, P. Nelson-Filho, R. Gerlach, I. Madalena
{"title":"Estrogen-deficiency Effect on the Composition of Dental Enamel: A Pilot Study","authors":"G. Fernandes, E. Küchler, M. Omori, G. Marañón‐Vásquez, L. Teixeira, J. León, C. Lopes, F. Baratto-Filho, P. Nelson-Filho, R. Gerlach, I. Madalena","doi":"10.4103/SDJ.SDJ_61_20","DOIUrl":"https://doi.org/10.4103/SDJ.SDJ_61_20","url":null,"abstract":"Background: Tooth enamel mineralization is assumed to be a target of endogenous estrogen imbalances. Objective: To evaluate the effect of estrogen deficiency during amelogenesis on the mineral composition of dental enamel. Methods: Ten female Wistar Hannover rats were randomly divided into two groups according to the intervention received: ovariectomy surgery (OVX, experimental) and fictitious surgery (SHAM, control). After 21 days, the rats of both groups were euthanized, and the upper incisors were extracted for analysis of the mineral composition by energy-dispersive X-ray fluorescence. The sensitivity of the enamel organ to estrogen was evaluated in both groups by immunohistochemical analysis of the odontogenic region of the lower incisors for the presence of estrogen receptors alpha and beta (ERα and ERβ, respectively) in ameloblasts in the maturation stage. Differences in the mineral composition between groups were compared using Student’s t-test (P < 0.05). Results: No statistically significant difference was detected in the mineral composition between the OVX and SHAM groups (P > 0.05). ERα was immunostained in the ameloblasts of both groups. Conclusion: Although ameloblasts express ERα, estrogen deficiency during amelogenesis did not appear to affect the dental enamel composition in this murine model.","PeriodicalId":32049,"journal":{"name":"Scientific Dental Journal","volume":"5 1","pages":"57 - 62"},"PeriodicalIF":0.0,"publicationDate":"2021-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46495572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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