Revista Medica del Hospital General de Mexico最新文献_第4页

A new siloxane embedded benzalkonium chloride-based skin protectant (fiteBac Germicidal Skin Softening Gel) for use against insect bites and related dermal infections 一种新型硅氧烷嵌入苯扎氯铵基皮肤保护剂(fiteBac杀菌皮肤软化凝胶)，用于防止昆虫叮咬和相关的皮肤感染

Revista Medica del Hospital General de Mexico Pub Date : 2018-07-01 DOI: 10.1016/j.hgmx.2018.03.001

Gerhard R.F. Krueger , Dharam V. Ablashi , Babak Baban , Clara Niedworok

{"title":"A new siloxane embedded benzalkonium chloride-based skin protectant (fiteBac Germicidal Skin Softening Gel) for use against insect bites and related dermal infections","authors":"Gerhard R.F. Krueger , Dharam V. Ablashi , Babak Baban , Clara Niedworok","doi":"10.1016/j.hgmx.2018.03.001","DOIUrl":"10.1016/j.hgmx.2018.03.001","url":null,"abstract":"<div><p>fiteBac Skin Softening Gel, widely used as a cosmetic, contains the anti-infective benzalkonium chloride embedded in siloxane quaternary ammonium compounds, but does not contain alcohol. It thus serves well for skin protection combined with local anti-infective activity. As it does not penetrate the skin, no systemic toxic side effects are expected, and more than 3 years of practical use have not revealed any adverse reactions.</p><p>We have tested in a pilot study the usefulness of fiteBac Skin Softening Gel against skin lesions following insect bites various in nature as well as a few other ailments (e.g. fungus-related intertrigo). Of the 23 cases tested, all but one responded to the treatment with complete resolution of skin lesions within a few days up to a week. The only exception was a case of suspected tick bite with local arthritic symptoms. In the latter, a combination of the fiteBac gel treatment with subsequent local administration of ibuprofen gel also resulted in complete remission of dermatitis and arthritis.</p><p>We thus recommend wider use of this cosmetic/anti-infective agent for the prevention and treatment of insect bites to prevent subsequent infectious complications (such as, for instance, Lyme disease).</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 3","pages":"Pages 115-121"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2018.03.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47626726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nephropathies with pattern of structural alterations of the glomerular basement membrane: Case study 肾小球基底膜结构改变型肾病：病例研究

Revista Medica del Hospital General de Mexico Pub Date : 2018-07-01 DOI: 10.1016/j.hgmx.2017.05.003

L.A. Pedroza , M.V. Soto-Abraham

{"title":"Nephropathies with pattern of structural alterations of the glomerular basement membrane: Case study","authors":"L.A. Pedroza , M.V. Soto-Abraham","doi":"10.1016/j.hgmx.2017.05.003","DOIUrl":"10.1016/j.hgmx.2017.05.003","url":null,"abstract":"<div><h3>Background</h3><p>The pattern of structural alterations of the glomerular basement membrane comprises two hereditary glomerular diseases: Alport syndrome (AS) and thin basement membrane nephropathy (TBMN); both are rare entities.</p></div><div><h3>Material and methods</h3><p>A retrospective, descriptive and observational study was carried out. A sample of 90 cases from Hospital General de México “Eduardo Liceaga” and the Instituto Nacional de Cardiología “Ignacio Chávez” were obtained over a period of 5 years (2011–2016). The diagnoses provided in all cases were reviewed and the clinical and histological spectrum was described. Data were analysed using descriptive statistics.</p></div><div><h3>Results</h3><p>Structural alterations of the basement membrane were found to be more frequent in women (60%), and occurred most frequently in the second decade of life. We found 38 cases (42.22%) compatible with TBMN and 52 cases (57.77%) with ultrastructural changes suggestive of Alport syndrome. Of the cases with characteristics compatible with AS, the majority were men (55.76%) with an average age of 14 years (3–39 years), starting with haematuria (42.30%); in the electron microscopy (EM), the glomerular basement membranes (GBM) measured on average 245.27nm, with very irregular ranges. The majority of patients with TBMN were women (81.57%) with an average age of 29 years (6–66 years) and with persistent microscopic haematuria at the time of diagnosis (47.36%); in the EM, the GBM averaged 170.63nm in thickness.</p></div><div><h3>Conclusions</h3><p>We report one of the largest case series in Latin America with respect to entities that share a morphological pattern via the study of optical microscopy, that of structural alterations of the glomerular basement membrane. With the EM study, both entities can be suggested.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 3","pages":"Pages 127-133"},"PeriodicalIF":0.0,"publicationDate":"2018-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2017.05.003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47589706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chagas disease: Current perspectives on a forgotten disease 恰加斯病:对一种被遗忘疾病的当前看法

Revista Medica del Hospital General de Mexico Pub Date : 2018-07-01 DOI: 10.1016/j.hgmx.2016.09.010

D.-A. Álvarez-Hernández , G.-A. Franyuti-Kelly , R. Díaz-López-Silva , A.-M. González-Chávez , D. González-Hermosillo-Cornejo , R. Vázquez-López

引用次数: 32

Giant cell tumour of the first cuneiform: Case study 第一楔状体巨细胞瘤:个案研究

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2016.05.015

J.A. Enríquez-Castro , G. Estévez-Díaz , A.F. Sánchez-Chávez , C.A.J. Mangas-Loria

引用次数: 0

Appendagitis acute, a rare cause of abdominal pain: A case report 急性阑尾炎，罕见的腹痛原因:1例报告

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2016.04.007

S.I. Gamboa-Hoil , Y.G. De la Paz-Ponce , F. Pat-Cruz , H.G. Heredia-Barrera , J. Rivero-Osorio

引用次数: 0

Paraneoplastic hypercalcaemia and osteolytic lesions secondary to large B-cell lymphoma: Case report and literature review 大b细胞淋巴瘤继发的副肿瘤性高钙血症和溶骨性病变:病例报告和文献复习

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2016.05.014

Dora Luisa Covarrubias-Flores , Ramón Adrián García-Galaviz , A. Silva-Carmona

引用次数: 2

Superior vena cava syndrome: Clinical considerations 上腔静脉综合征:临床考虑

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2017.03.004

B. Pech-Alonso , C. Fermín-Hernández , S.I. Saavedra-de Rosas , R.J. Cicero-Sabido

引用次数: 7

Parasitosis in the bile duct, report of 3 cases and literature review 胆管寄生虫病附3例报告并文献复习

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2016.06.009

J.A. Garcia-Espinoza , S. Vásquez-Ciriaco , R. Doña-Jaimes , R. Aragon-Soto , C. Velazco-Budar , E. López-Martínez

{"title":"Parasitosis in the bile duct, report of 3 cases and literature review","authors":"J.A. Garcia-Espinoza , S. Vásquez-Ciriaco , R. Doña-Jaimes , R. Aragon-Soto , C. Velazco-Budar , E. López-Martínez","doi":"10.1016/j.hgmx.2016.06.009","DOIUrl":"10.1016/j.hgmx.2016.06.009","url":null,"abstract":"<div><h3>Background</h3><p>Roundworm has a worldwide incidence of 25% of the population and biliary ascariasis accounts for 10–17% of all cases of roundworm infestation, predominantly in developing countries in tropical and subtropical climates. In the bile duct, it causes pyogenic cholangitis (stenosis and pigmented stones), cholecystitis, pancreatitis and liver abscesses.</p></div><div><h3>Clinical cases</h3><p>We present the cases of three patients who showed symptoms of biliary disease. Only one of the three cases had imaging data (ultrasound) compatible with biliary ascariasis. However the other two cases had biliary disease mimicking cholecystitis and cholangitis and diagnosis was confirmed at the time of surgical exploration.</p></div><div><h3>Conclusions</h3><p>The management of biliary ascariasis rests on three main pillars according to severity. It starts with medical management, followed by endoscopic if the conservative option fails, and finally surgical management in selected cases, with a favourable prognosis in the majority of patients.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 ","pages":"Pages 18-23"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.06.009","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54295290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Palliative prognostic index and Charlson comorbidity index as predictors of mortality in acute lymphoblastic leukaemia patients who are candidates for palliative care 姑息预后指数和Charlson合并症指数作为急性淋巴细胞白血病患者姑息治疗候选人死亡率的预测因子

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2016.09.008

R.A. Trejo-Ayala , C.O. Ramos-Peñafiel , A. Santoyo-Sánchez , E. Rozen-Fuller , I. Olarte-Carrillo , J. Collazo-Jaloma , A. Martínez-Tovar

{"title":"Palliative prognostic index and Charlson comorbidity index as predictors of mortality in acute lymphoblastic leukaemia patients who are candidates for palliative care","authors":"R.A. Trejo-Ayala , C.O. Ramos-Peñafiel , A. Santoyo-Sánchez , E. Rozen-Fuller , I. Olarte-Carrillo , J. Collazo-Jaloma , A. Martínez-Tovar","doi":"10.1016/j.hgmx.2016.09.008","DOIUrl":"10.1016/j.hgmx.2016.09.008","url":null,"abstract":"<div><h3>Objective</h3><p>To establish whether the palliative prognostic index (PPI), the Charlson comorbidity index (CCI) or other factors are predictors of survival for patients with ALL undergoing palliative care.</p></div><div><h3>Materials and methods</h3><p>Retrospective cohort study of patients diagnosed with ALL undergoing palliative care. We analysed variables at the time of diagnosis (age, WBC count, and risk type), chemotherapy regimens received, PPI, CCI and transfusion requirements at time palliative care was started.</p></div><div><h3>Results</h3><p>We studied 32 patients with a mean age of 37 (18–75) years. Fourteen cases had a PPI=0 (43.8%). 62.5% (<em>n</em>    <!-->3 had high odds of dying within 10 years. The median survival was 200 days, unaffected by any of the factors analysed.</p></div><div><h3>Discussion</h3><p>Neither PPI, CCI, nor the other studied factors effectively predicted survival. Scales will have to be adapted or new predictive scales devised specifically for patients with ALL.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 2","pages":"Pages 79-85"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.09.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54295670","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Expression of genes MAGE-A3 MAGE-C1, NY-ESO-1 and SSX1 in patients with multiple myeloma at the General Hospital of Mexico 墨西哥总医院多发性骨髓瘤患者MAGE-A3、MAGE-C1、NY-ESO-1和SSX1基因的表达

Revista Medica del Hospital General de Mexico Pub Date : 2018-04-01 DOI: 10.1016/j.hgmx.2016.06.008

A. De la Cruz-Rosas , A. Martínez-Tovar , C. Ramos-Peñafiel , R. Cerón-Maldonado , A. García-Laguna , I. Mendoza-Salas , E. Miranda-Peralta , J. Collazo-Jaloma , I. Olarte-Carrillo

{"title":"Expression of genes MAGE-A3 MAGE-C1, NY-ESO-1 and SSX1 in patients with multiple myeloma at the General Hospital of Mexico","authors":"A. De la Cruz-Rosas , A. Martínez-Tovar , C. Ramos-Peñafiel , R. Cerón-Maldonado , A. García-Laguna , I. Mendoza-Salas , E. Miranda-Peralta , J. Collazo-Jaloma , I. Olarte-Carrillo","doi":"10.1016/j.hgmx.2016.06.008","DOIUrl":"10.1016/j.hgmx.2016.06.008","url":null,"abstract":"<div><p>Multiple myeloma is the most common form of plasma cell cancer. It is a disease of elderly people, with a mean age at diagnosis of 65–70, and represents 10–15% of all blood cancers. It is a heterogeneous disease associated with intrinsic factors and disease characteristics such as genetics, which dictate the clinical course of the disease. Multiple myeloma involves several abnormalities in the IgH variable region. The first oncogenic events in this cancer occur in the germinal centre, apparently during isotype switching and somatic hypermutation of B cells. While these primary mutations have been found in myeloma cells, these events alone are not enough to cause pathogenesis. However, few genes have been identified in this type of disease. The expression of cancer/testis antigens (CTAs) is limited to testis tissue and various types of cancer, in which they are considered as a tumour marker as they are associated with the prognosis and monitoring of the disease, and are involved with overall survival and event-free disease. In view of the above, the objective of this study was to analyse the expression of CTAs (MAGE-A3 and -C1, NY-ESO and SSX1) by RT-PCR in patients diagnosed with <em>de novo</em> multiple myeloma admitted to the Haematology Department of Hospital General de México. Our results proved that there is presence of these genes and that they may be involved in resistance, progression and survival.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"81 2","pages":"Pages 86-92"},"PeriodicalIF":0.0,"publicationDate":"2018-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.06.008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54295265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0