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Synthesis of Goethite (α-FeOOH) Pigment by Precipitation Method from Iron Lathe Waste 沉淀法合成针铁矿(α-FeOOH)颜料
Alchemy Journal of Chemistry Pub Date : 2018-10-30 DOI: 10.18860/AL.V6I2.7106
L. M. Khoiroh, E. . Nuraini, N. Aini
{"title":"Synthesis of Goethite (α-FeOOH) Pigment by Precipitation Method from Iron Lathe Waste","authors":"L. M. Khoiroh, E. . Nuraini, N. Aini","doi":"10.18860/AL.V6I2.7106","DOIUrl":"https://doi.org/10.18860/AL.V6I2.7106","url":null,"abstract":"Lathe waste contains high iron content potential to be further processed into goethite pigment. The purpose of the research was to determine the effect of synthesis temperature on the structure, colour values, and morphology of goethite pigment. The synthesis was conducted with temperature variations of 60, 70, 80and 90°C. The XRD diffraction pattern shows that crystal structure of the product of all synthesis temperatures are goethite (α-Fe-OOH) with orthorhombic structure. The crystal size of the pigment ranges between 11.17 – 12.32 nm. Colour value analysis shows that product of 70°C synthesis temperature exhibits the highest lightness value about 40.5. Based on SEM-EDX imaging, the morphology of the samples is not uniform and forming agglomerates. Traces of impurities were detected, such as C and Na. Keywords: Iron lathe waste, goethite, temperature, precipitation","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76817232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Kopling Oksidatif Eugenol Menggunakan Ekstrak Enzim Peroksidase dari Akar Tanaman Sawi Hijau serta Uji Bioaktivitasnya 绿锯木属植物酸过氧化物酶提取物的Eugenol氧化连接及其生物活性测试
Alchemy Journal of Chemistry Pub Date : 2018-01-30 DOI: 10.18860/AL.V5I3.3776
B. Ardiansah, A. Cahyana, W. P. Suwarso, Rianti Maryana, Siti Merly
{"title":"Kopling Oksidatif Eugenol Menggunakan Ekstrak Enzim Peroksidase dari Akar Tanaman Sawi Hijau serta Uji Bioaktivitasnya","authors":"B. Ardiansah, A. Cahyana, W. P. Suwarso, Rianti Maryana, Siti Merly","doi":"10.18860/AL.V5I3.3776","DOIUrl":"https://doi.org/10.18860/AL.V5I3.3776","url":null,"abstract":"Peroxidase has been successfully extracted and partially purified from Brassica juncea L. Czern root with protein content and specific activity of 0.747 mg/mL and 0.244 U/mg, respectively. Then, it was applied as biocatalyst for green oxidative coupling reaction of eugenol to produce an orange crystal, dimeric form of eugenol (84% yield). Structure elucidation was done by using FTIR, UV-Vis and GC-MS instruments. The optical activity of dimeric eugenol was found to have Ra-configuration. Furthermore, biological activity of the product as antioxidant has been evaluated resulting in IC50 values of 32.14 and 42.43 ppm for dimeric and monomeric eugenol, respectively.","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43143619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
ANALISIS HKSA SENYAWA ANTIDIABETIK TURUNAN TRIAZOLOPIPERAZIN AMIDA MENGGUNAKAN METODE SEMIEMPIRIK PM3 semly PM3法测定三唑嗪酰胺的抗糖尿病活性
Alchemy Journal of Chemistry Pub Date : 2018-01-16 DOI: 10.18860/al.v5i4.4045
A. Asmara, M.Eng. Mudasir, Dwi Siswanta
{"title":"ANALISIS HKSA SENYAWA ANTIDIABETIK TURUNAN TRIAZOLOPIPERAZIN AMIDA MENGGUNAKAN METODE SEMIEMPIRIK PM3","authors":"A. Asmara, M.Eng. Mudasir, Dwi Siswanta","doi":"10.18860/al.v5i4.4045","DOIUrl":"https://doi.org/10.18860/al.v5i4.4045","url":null,"abstract":"Analisis hubungan kuantitatif struktur dan aktivitas (HKSA) dilakukan untuk senyawa turunan triazolopiperazin amida untuk menghibisi enzim DPP IV penyebab diabetes melitus tipe 2. Analisis ini dilakukan dengan pemodelan molekul turunan triazolopiperazin amida dan perhitungan deskriptor HKSA menggunakan metode semiempirik PM3 dengan program Hyperchem O . Analisis data menggunakan metode analisis regresi multilinear untuk parameter elektronik dan molekular dengan program SPSS O . Persamaan terbaik yang diperoleh adalah: -log IC 50 = 79,955 - (11,635*qC1) - (2,094*qC2) - (34,6*qN11) + (797,684*qC15) + (0,288*m)  n = 18; r = 0,714; adjusted r 2 = 0,305; F hit / F tab = 1,239; PRESS = 0,017. Berdasarkan persamaan tersebut, senyawa dengan aktivitas terbaik yang diusulkan adalah: ( (2 R )-4-Okso-4-[3-(Trifluorometil)-5,6-dihidro[1,2,4]triazolo[4,3- a ]pirazin-7(8 H )-il]-1-(2-fluoro-4,6-dihidroksofenil)butan-2-amina dengan harga –log IC 50 = 8,601.","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47551934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Isolasi dan Karakterisasi Hidroksiapatit dari Limbah Tulang Hewan 任何动物骨髓的分离和水力特性
Alchemy Journal of Chemistry Pub Date : 2018-01-16 DOI: 10.18860/al.v5i4.4705
Vina Amalia, Eko Prabowo Hadisantoso, Dede Hidayat, Riska Farah Diba, Muhamad Fahmi Dermawan, Siti Wilamah Tsaniyah
{"title":"Isolasi dan Karakterisasi Hidroksiapatit dari Limbah Tulang Hewan","authors":"Vina Amalia, Eko Prabowo Hadisantoso, Dede Hidayat, Riska Farah Diba, Muhamad Fahmi Dermawan, Siti Wilamah Tsaniyah","doi":"10.18860/al.v5i4.4705","DOIUrl":"https://doi.org/10.18860/al.v5i4.4705","url":null,"abstract":"Tulang vertebrata mengandung 60% kalsium fosfat. yang dapat dimanfaatkan sebagai bahan dasar hidroksiapatit. Hidroksiapatit merupakan material biokeramik yang memiliki sifat adsorpsi yang baik sehingga dapat dimanfaatkan sebagai adsorben. Penelitian ini bertujuan untuk mengisolasi dan mengkarakterisasi hidroksiapatit dari beberapa limbah tulang, yaitu tulang sapi, kambing, gurame, dan tongkol. Hidroksiapatit dari limbah  tulang sapi dan kambing diisolasi dengan cara kalsinasi pada suhu 1000°C dan diaktivasi menggunakan Na 2 CO 3 . Isolasi hidroksiapatit dari limbah tulang gurame dan tulang tongkol tidak dilakukan kalsinasi hanya digunakan hidrolisis menggunakan NaOH. Karakterisasi menggunakan XRD menunjukkan bahwa telah terbentuk hidroksiapatit kristalin dari hasil isolasi tulang sapi dan kambing, dan terbentuk hidroksiapatit amorf dari hasil isolasi tulang gurame dan tongkol. Perbandingan Ca/P hidroksiapatit hasil isolasi dari tulang sapi, kambing, gurame, dan tongkol, masing-masing adalah 1,71; 1,79; 1,97 dan 1,86. Spektra IR hidroksiapatit menunjukkan adanya gugus –OH, PO 4 3- , dan CO 3 2- . Morfologi permukaan hidroksiapatit hasil isolasi berpori dengan ukuran partikel 1-2 µm.","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43404403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Green Synthesis Senyawa Imina dari Vanillin and Anilina dengan Katalis Alami Air Jeruk Nipis (Citrus aurantifolia) 以香兰素和苯胺为原料,以尼皮斯黄水(枳壳)为天然催化剂绿色合成Senyawa亚胺
Alchemy Journal of Chemistry Pub Date : 2018-01-16 DOI: 10.18860/al.v5i4.4706
Nurush Shofi al Hakimi, Ahmand Hanapi, A. Fasya
{"title":"Green Synthesis Senyawa Imina dari Vanillin and Anilina dengan Katalis Alami Air Jeruk Nipis (Citrus aurantifolia)","authors":"Nurush Shofi al Hakimi, Ahmand Hanapi, A. Fasya","doi":"10.18860/al.v5i4.4706","DOIUrl":"https://doi.org/10.18860/al.v5i4.4706","url":null,"abstract":"Sintesis imina dari vanilin dan anilina dapat dilakukan tanpa pelarut dengan bantuan katalis asam alami dari jeruk nipis (Citrus aurantifolia). Penelitian ini bertujuan untuk mengkarakterisasi produk imina dengan variasi volume katalis jeruk nipis. Volume katalis jeruk nipis yang digunakan adalah 0,5; 1,0; 1,5; 2,0; dan 2,5 mL. Produk imina dikarakterisasi berdasarkan bentuk, warna, titik lebur dan rendemen. Produk juga identifikasi menggunakan FTIR dan KG-SM. Sintesis imina menghasilkan P1 sebagai produk terbaik dengan rendemen sebesar 64,12% dan tingkat kemurnian 74,74%. Hasil karakterisasi produk imina berupa padatan yang berwarna kuning dengan titik lebur 150°C. Hasil KG-SM menunjukkan adanya senyawa target sintesis 2-metoksi-4-((fenilimino)metil)fenol pada m/z 227 (M *+ ). Terbentuknya senyawa target diperkuat dengan spektra IR khas senyawa imina (C=N) pada 1584 cm -1 .","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45033102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bioethanol Dehydration Process using NaOH-Activated Zeolite at Various Concentration and Zeolite Weight 不同浓度和分子筛重量的NaOH活化分子筛生物乙醇脱水工艺
Alchemy Journal of Chemistry Pub Date : 2018-01-09 DOI: 10.18860/AL.V4I1.3140
David Saidi, A. Jannah, A. Maunatin
{"title":"Bioethanol Dehydration Process using NaOH-Activated Zeolite at Various Concentration and Zeolite Weight","authors":"David Saidi, A. Jannah, A. Maunatin","doi":"10.18860/AL.V4I1.3140","DOIUrl":"https://doi.org/10.18860/AL.V4I1.3140","url":null,"abstract":"Utilization of molasses as basic material for producing bioethanol becomes one of the promising efforts to fulfill the demand of fuel and diminish the dependence upon fossil fuel that its availability is increasingly rare. However, ethanol produced from fermentation of molasses has low purity. The purity could be increased by using dehydration method and zeolite activated by NaOH and alum as alumina source. The research is aimed to know the dehydration process of bioethanol use NaOH-activated zeolite at various concentration and zeolite weight on the purification of bioethanol. In this research, the experiments could be categorized into 4 groups, they are activation of zeolite, fermentation, distillation, and dehydration process. Activation of natural zeolite performed by entering of sized 120-150 mesh zeolite powder was added to glass beaker that contains  NaOH aqueous solution and followed by adding alum which took place at 80 ˚C for 8 hours and the final product calcinated at 600 ˚ C for 2 hour. Fermentation process was managed for 6 days and pH 5. Furthermore, bioethanol was separated by distillation method at 78,5 - 85 ˚C and followed by molecular sieve dehydration using zeolite activated by NaOH solution in variation of zeolite weight (30, 40 and 50 %) and NaOH concentration (1, 2, 3 dan 4 M). The amount of bioethanol was measured by gas chromatography method. Bioethanol concentration as fermentation product is 29,8 %. The result revealed that dehydration with 30% w.t zeolite activated by 2 M NaOH solution had the best activity in bioethanol purification with amount of bioethanol is 53,76 %, Increased Levels of Bioethanol (ILB) value is 80,39 % and Adsorption Capacity of Zeolite (ACZ) is 399,31 %. Keywords: bioethanol, concentration of NaOH, dehydration, molasses, molecular sieve, weight of zeolite","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43206763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Synthesis and Characterization Titanium Dioxide (TiO2) Doped Vanadium(V) Using Solid State Method 固态法合成掺杂钒(V)的二氧化钛(TiO2)及其表征
Alchemy Journal of Chemistry Pub Date : 2018-01-09 DOI: 10.18860/AL.V4I1.3143
K. Mustofa, N. Aini, S. N. Khalifah
{"title":"Synthesis and Characterization Titanium Dioxide (TiO2) Doped Vanadium(V) Using Solid State Method","authors":"K. Mustofa, N. Aini, S. N. Khalifah","doi":"10.18860/AL.V4I1.3143","DOIUrl":"https://doi.org/10.18860/AL.V4I1.3143","url":null,"abstract":"TiO 2 Anatase activities should be increased from the UV to the visible light photocatalytic activity of TiO 2 to increase anatas. One efforts to optimize TiO 2 anatase activity is doping by using dopant vanadium(V). Synthesis method which is used in this research is a solid reaction method. The steps being taken in this methods include grinding and heating at high temperatures. Dopant concentrations of vanadium(V) which are used in the research was 0.3%, 0.5% and 0.7%. and the characterization used is X-ray diffraction and UV-Vis Diffuse Reflectance Spectroscopy. The result shows that there are a changing of particle size, band gap energy, and absorption of TiO 2 anatas wavelength because of dopan vanadium(V) addition. While TiO 2 ’s structure does not change. The crystal sizes of each TiO 2 without doping, V-TiO 2 0,3%, 0,5% and 0,7% are 53.21 nm, 47.67 nm, 79.65 nm dan 68.99 nm.  Band gap energy of each TiO 2 without doping, V-TiO 2 0,3%, 0,5% dan 0,7% are 3.309 eV, 3.279 eV, 3.270 eV and 3.259 eV. While wavelength absorption of each TiO 2 without doping, V-TiO 2 0,3%, 0,5% and 0,7% are 374.9 nm, 378.4 nm, 379.5 nm and 380.8 nm. Keywords : Synthesis, titanium dioxide, vanadium(V), solid state method","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41873798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Pemanfaatan Biosorben Batang Jagung Teraktivasi Asam Nitrat dan Asam Sulfat untuk Penurunan Angka Peroksida – Asam Lemak Bebas Minyak Goreng Bekas 玉米茎的生物递质使用是硝酸和硫酸,用于降低过氧化氢数字——不含旧食用油的脂肪酸
Alchemy Journal of Chemistry Pub Date : 2018-01-09 DOI: 10.18860/AL.V5I1.3685
Eny Yulianti, Rif'atul Mahmudah, Isna Royana
{"title":"Pemanfaatan Biosorben Batang Jagung Teraktivasi Asam Nitrat dan Asam Sulfat untuk Penurunan Angka Peroksida – Asam Lemak Bebas Minyak Goreng Bekas","authors":"Eny Yulianti, Rif'atul Mahmudah, Isna Royana","doi":"10.18860/AL.V5I1.3685","DOIUrl":"https://doi.org/10.18860/AL.V5I1.3685","url":null,"abstract":"Batang jagung merupakan limbah pertanian yang mengandung kadar selulosa tinggi yang dapat dimanfaatkan sebagai biosorben dalam pemurnian minyak goreng bekas. Penelitian ini akan mempelajari pengaruh konsentrasi asam sulfat dan asam nitrat sebagai aktivator biosorben terhadap penurunan angka peroksida dan asam lemak bebas (ALB) pada proses bleaching . Pembuatan biosorben dari batang jagung dilakukan dengan cara delignifikasi dan aktivasi kimia menggunakan aktivator asam sulfat dan asam nitrat dengan berbagai variasi konsentrasi. Pemurnian minyak goreng bekas dengan cara despicing , netralisasi dan bleaching .Hasil penelitian menunjukan bahwa biosorben batang jagung teraktivasi H 2 SO 4 dan HNO 3 yang digunakan pada proses bleaching minyak goreng bekas dapat menurunkan angka peroksida dan ALB. Penurunan angka peroksida terbesar pada proses bleaching oleh biosorben teraktivasi H 2 SO 4 10% dan teraktivasi HNO 3 1 M mencapai 9,53% dan 14,12%, berturut-turut.  Penurunan terbesar kadar ALB pada proses bleaching sebesar 8,65% pada biosorben teraktivasi H 2 SO 4 20% dan 8,63% pada biosorben teraktivasi HNO 3 1 M. Hasil analisis spektra FTIR biosorben yang telah digunakan pada proses bleaching menunjukan adanya gugus fungsi baru C-H metilen (2855 cm -1 ) dan C=O ester (1742 cm -1 ) yang diduga merupakan peroksida dan ALB yang teradsorpsi secara kimia oleh biosorben. Hasil analisis statisitik ANOVA menunjukan bahwa variasi konsentrasi asam sulfat dan asam nitrat tidak mempunyai pengaruh terhadap penurunan angka peroksida, akan tetapi mempunyai pengaruh terhadap penurunan ALB","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48839416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Ekstraksi, Hidrolisis dan Partisi Metabolit Sekunder dari Mikroalga Chlorella sp. 从sp微藻中提取、水解和次级代谢颗粒。
Alchemy Journal of Chemistry Pub Date : 2018-01-09 DOI: 10.18860/al.v5i1.3686
A. Fasya, Anike Riska Dinasti, Muharromatus Shofiyah, L. Rahmawati, N. Millati, Dany Aulia Safitri, S. Handoko, Ahmad Hanapi, Rachmawati Ningsih
{"title":"Ekstraksi, Hidrolisis dan Partisi Metabolit Sekunder dari Mikroalga Chlorella sp.","authors":"A. Fasya, Anike Riska Dinasti, Muharromatus Shofiyah, L. Rahmawati, N. Millati, Dany Aulia Safitri, S. Handoko, Ahmad Hanapi, Rachmawati Ningsih","doi":"10.18860/al.v5i1.3686","DOIUrl":"https://doi.org/10.18860/al.v5i1.3686","url":null,"abstract":"Mikroalga Chlorella sp. adalah tumbuhan tingkat rendah yang mengandung metabolit sekunder yaitu senyawa steroid. Penelitian ini bertujuan untuk mendapatkan senyawa metabolit sekunder yang terkandung dalam mikroalga Chlorella sp. berdasarkan kelarutannya terhadap pelarut etil asetat dan petroleum eter. Chlorella sp. dikultivasi dalam Media Ekstrak Tauge (MET) 4% dan pemanenannya dilakukan pada hari ke-10. Biomassa hasil panen diukur kadar air dengan teknik termogravimetri dan dimaserasi menggunakan pelarut methanol. Ekstrak kasar hasil maserasi dihidrolisis dengan HCl 2 N dan dipartisi dengan masing-masing pelarut etil asetat dan petroleum eter. Hasil penelitian menunjukkan bahwa rendemen hasil ekstraksi pada pelarut metanol adalah 21,89 %. Rendemen hasil hidrolisis dan partisi adalah 80,95% untuk fraksi etil asetat dan 50,63% untuk fraksi petroleum eter.","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47007862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines 巨脊藻根、叶、花乙醇提取物对T47D乳腺癌症细胞系抗癌作用的比较
Alchemy Journal of Chemistry Pub Date : 2018-01-09 DOI: 10.18860/AL.V5I1.3690
R. Mutiah, Sukardiman Sukardiman, A. Widyawaruyanti, S. Zulaikah
{"title":"Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines","authors":"R. Mutiah, Sukardiman Sukardiman, A. Widyawaruyanti, S. Zulaikah","doi":"10.18860/AL.V5I1.3690","DOIUrl":"https://doi.org/10.18860/AL.V5I1.3690","url":null,"abstract":"This research aims to find out the anticancer activity of ethanol extract from the roots, leaves, and flowers of Calotropis gigantea . This experiment was conducted by MTT method on T47D breast cancer cell line. The result showed that the root of Calotropis gigantea was more cytotoxic (IC 50 89.76 μg/mL) on T47D breast cancer cell line than the leaves (IC 50 459.51 μg/mL) and the flowers (IC 50 >1000). Based on the result, roots are potent to be chemotherapeutic agent, especially in breast cancer.","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41266743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
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