R. Mutiah, Sukardiman Sukardiman, A. Widyawaruyanti, S. Zulaikah
{"title":"巨脊藻根、叶、花乙醇提取物对T47D乳腺癌症细胞系抗癌作用的比较","authors":"R. Mutiah, Sukardiman Sukardiman, A. Widyawaruyanti, S. Zulaikah","doi":"10.18860/AL.V5I1.3690","DOIUrl":null,"url":null,"abstract":"This research aims to find out the anticancer activity of ethanol extract from the roots, leaves, and flowers of Calotropis gigantea . This experiment was conducted by MTT method on T47D breast cancer cell line. The result showed that the root of Calotropis gigantea was more cytotoxic (IC 50 89.76 μg/mL) on T47D breast cancer cell line than the leaves (IC 50 459.51 μg/mL) and the flowers (IC 50 >1000). Based on the result, roots are potent to be chemotherapeutic agent, especially in breast cancer.","PeriodicalId":31035,"journal":{"name":"Alchemy Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2018-01-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"11","resultStr":"{\"title\":\"Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines\",\"authors\":\"R. Mutiah, Sukardiman Sukardiman, A. Widyawaruyanti, S. Zulaikah\",\"doi\":\"10.18860/AL.V5I1.3690\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This research aims to find out the anticancer activity of ethanol extract from the roots, leaves, and flowers of Calotropis gigantea . This experiment was conducted by MTT method on T47D breast cancer cell line. The result showed that the root of Calotropis gigantea was more cytotoxic (IC 50 89.76 μg/mL) on T47D breast cancer cell line than the leaves (IC 50 459.51 μg/mL) and the flowers (IC 50 >1000). Based on the result, roots are potent to be chemotherapeutic agent, especially in breast cancer.\",\"PeriodicalId\":31035,\"journal\":{\"name\":\"Alchemy Journal of Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-01-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Alchemy Journal of Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.18860/AL.V5I1.3690\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Alchemy Journal of Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18860/AL.V5I1.3690","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Comparison of Ethanol Extract from Roots, Leaves, and Flowers of Calotropis gigantea as Anticancer on T47D Breast Cancer Cell Lines
This research aims to find out the anticancer activity of ethanol extract from the roots, leaves, and flowers of Calotropis gigantea . This experiment was conducted by MTT method on T47D breast cancer cell line. The result showed that the root of Calotropis gigantea was more cytotoxic (IC 50 89.76 μg/mL) on T47D breast cancer cell line than the leaves (IC 50 459.51 μg/mL) and the flowers (IC 50 >1000). Based on the result, roots are potent to be chemotherapeutic agent, especially in breast cancer.
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