Journal of Birjand University of Medical Sciences最新文献

{"title":"Effect of moderate intensity aerobic training on cardiac autonomic system function and nitric oxide levels in middle-aged males with metabolic syndrome","authors":"Rabali Bolboli, M. Siahkouhian, Asgar Iranpour, Ameneh Pour Rahim, Aydin Vali Zadeh, Lotfali Bolboli","doi":"10.32592/jbirjandunivmedsci.2021.28.2.103","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2021.28.2.103","url":null,"abstract":"Background and Aims: The sedentary lifestyle in individuals with metabolic syndrome is a main threatening risk for their health. This study aimed to investigate the effects of aerobic exercise with 65% of maximal oxygen consumption on heart rate variability and vascular nitric oxide levels in middle-aged males with metabolic syndrome. Materials and Methods: In total, 30 middle-aged men with metabolic syndrome were randomly divided into control and aerobic training groups. At the pretest and posttest, the values ​​of metabolic risk indices, heart rate variability, and nitric oxide were measured in both groups. The aerobic training group performed aerobic exercise for eight weeks at 65% of maximal oxygen consumption. The data were analyzed using the independent and paired t-tests. Results: According to the results, after comparing the values obtained from the posttest and pretest, there was a significant difference between the training and control groups regarding the fasting blood glucose, triglyceride, metabolic Z score, Standard deviation of NN intervals (SDNN), Square root of the mean squared differences of successive NN intervals (rMSSD), very-low-frequency (VLF), High frequency (HF), and vascular nitric oxide levels. Total cholesterol and low-density lipoprotein levels were significantly different in the aerobic training group, compared to those of the control group and LF as well as LF/HF at the pretest (P=0.01). However, despite slight changes in high lipoprotein and blood pressure levels, there was no significant difference in the aerobic training group, compared to the control group and pre-test. Conclusion: Regular moderate-intensity aerobic exercise can be used as an appropriate exercise protocol to improve cardiovascular function for males with metabolic syndrome.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69704980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of COVID-19 patients using plasma therapy: Letter to Editor","authors":"Nafiseh Erfanian, E. Miri-Moghaddam","doi":"10.32592/jbirjandunivmedsci.2021.28.1.109","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2021.28.1.109","url":null,"abstract":"The symptoms of COVID-19, caused by the newly known type of coronavirus, vary widely from asymptomatic, mild to severe respiratory infection leading to hospitalization or death of patients. To date, no specific drug has been reported for the treatment of patients affected by this virus. One of the approaches adopted for the treatment of this disease is the use of plasma therapy, which contains antibodies against the virus. Following of the plasma therapy have not been reported any serious side effects. Currently, the numbers of these studies are limited, and evaluation of the larger population studies can provide stronger evidence for treating physicians about the effectiveness of this therapeutic approach.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82895968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Sclerorhachis leptoclada hydroalcoholic extract on glucose and cholesterol levels, triglyceride, Serum HDL and LDL in male diabetic rats","authors":"O. Eshghi, M. Tehranipour, J. Baharara, Nastaran Amintaheri","doi":"10.32592/jbirjandunivmedsci.2020.27.4.103","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2020.27.4.103","url":null,"abstract":"Background and Aim: Diabetes is a metabolic disorder in the body. Sclerorhachis leptoclada belongs to the chicory family, is used to treat aids and cancer due to the antioxidant compounds in the root. Therefore, in this study, the effect of hydroalcoholic extract of Sclerorhachis leptoclada on glucose and cholesterol, triglyceride, high density lipoprotein (HDL) and low density lipoprotein (LDL) levels in diabetic rats was investigated.\u0000Materials and Methods: In this experimental study, 60 male Wistar rats were randomly divided into 10 groups of 6: Control group, treatment groups 1, 2, and 3 (healthy, treated with 150 mg/kg and 300 and 600 extracts), Diabetic control group, experimental groups 1, 2 and 3 (diabetic, treated with doses of 150 mg/kg and 300 and 600 extracts), Positive control group (diabetic+glibenclamide), The healthy group (healthy+glibenclamide) was divided. After one month of gavage, blood samples were taken from the rats, and glucose, urea, creatinine, and albumin levels were measured. A comparison was made between the effect of hydroalcoholic extract of Sclerorhachis leptoclada and the common drug glibenclamide and the results of the groups were compared by using t-test and ANOVA.\u0000Results: The results showed that the administration of hydroalcoholic extract of Sclerorhachis leptoclada can significantly reduce glucose levels in experimental groups (diabetic+extract at doses of 150, 300, 600) compared with the diabetic group (p<0.001) Also, the consumption of hydroalcoholic extract of Sclerorhachis leptoclada in diabetic patients causes a significant reduction in triglyceride, HDL and LDL levels in diabetic rats and has hypoglycemic effects.\u0000Conclusion: The results of this study showed that the consumption of hydroalcoholic extract of Sclerorhachis leptoclada in diabetic rats significantly reduces serum levels of glucose, triglyceride and creatinine in diabetic rats and has hypoglycemic effects","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91062675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of efficacy and safety of three drugs levetiracetam, sodium valproate, and nortriptyline in the prevention of migraine headache","authors":"H. Riasi, A. Akbari, Z. Ahani, Sayed Mohammad Musavi Mirzaee","doi":"10.32592/jbirjandunivmedsci.2020.27.4.102","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2020.27.4.102","url":null,"abstract":"Background and Aims: Headache is the most common reason for referring to a physician. Therapeutic approaches of this condition include the treatment of the acute attacks and prevention of future attacks. In this regard, this study aimed to investigate the effect of three medications, namely levetiracetam, sodium valproate, and nortriptyline on the control of migraine headaches in patients with migraine referred to Birjand Neurology Clinic, Birjand, Iran. Materials and Methods: This study was conducted based on a quasi-experimental research method. According to the physician, 120 migraine patients were divided into three groups of levetiracetam (a daily dose of 250 mg), sodium valproate (500 mg), and nortriptyline (25 mg) for four weeks. A questionnaire was used to collect the demographic characteristics of the patient. The data were analyzed using SPSS software (version 16) through the chi-square tets, paired t-test, and ANOVA. Results: The patients (n=120) were divided into three groups of 40 cases per group. The mean age of the patients was 33±11 years, and the majority of the cases (53.3%) were female. In total, 46.7% of the cases had severe headache before taking these medications; however, none of them experienced severe headache after taking the medicine. It should be noted that 77.5% of the patients experienced mild headache. The group taking levetiracetam showed the greatest decrease in headache intensity (P=0.01). Conclusion: According the results, levetiracetam appears to be more effective than the other two medications, especially sodium valproate, in terms of the mitigation of different degrees of headache.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44076010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of intra-articular injection of bupivacaine with morphine or methylprednisolone or alone on pain after knee arthroscopy","authors":"H. Kayalha, A. Alizadeh, Hoda Shahamat, Idin Binazadeh, S. Rastak, M. Sofiabadi","doi":"10.32592/jbirjandunivmedsci.2020.27.4.100","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2020.27.4.100","url":null,"abstract":"Background and Aims: Knee arthroscopy is used to diagnose and treat intra-articular lesions. The control of acute pain after arthroscopy requires the use of a method with the least side effects and most efficacies. This study aimed to compare the sedative effect of bupivacaine in combination with morphine, methylprednisolone, or alone in knee arthroscopy after intra-articular injection. Materials and Methods: This clinical-randomized three-blind trial included 99 volunteer patients with knee arthroscopy. The patients were randomly divided into three groups of bupivacaine (0.5%), morphine (5 mg)+bupivacaine (0.5%), and methylprednisolone (40 mg)+bupivacaine (0.5%). At the end of the surgical operation, the intra-articular injection of the medications were performed, and the amount of postoperative pain was evaluated and recorded based on visual analog scale 6, 12, 18, and 24 h after injection. In addition, the reception of the injected analgesic within 24 h was recorded in this study. Data were analyzed using SPSS software (version 19) through ANOVA. Results: In all three groups, the pain intensity decreased significantly over time. The pain intensity of the methylprednisolone+bupivacaine and morphine+bupivacaine groups was similar at different postoperative periods; however, the pain intensity of these groups was significantly lower than that in the control group. In addition, consumption of the analgesics was significantly reduced in the methylprednisolone+bupivacaine group, compared to the other two groups. Conclusion: The results of this study showed that the intra-articular injection of methylprednisolone+bupivacaine and morphine+bupivacaine was more effective than bupivacaine alone in reduction of pain and the need for injectable analgesia.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48601049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of G22A variant of Adenosine Deaminase gene (ADA) with coronary-in-stent restenosis in coronary artery patients receiving drug-eluting stent: Short Communication","authors":"","doi":"10.32592/jbirjandunivmedsci.2020.27.4.107","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2020.27.4.107","url":null,"abstract":"The main problem with using stents in the treatment of coronary artery atherosclerotic stenosis in percutaneous coronary intervention (PCI) is In-stent restenosis (ISR). In this study, we investigated the possible role of the G22A variant of the Adenosine Deaminase gene (ADA) in the development of ISR. In this study, 91 patients who underwent PCI were divided into two groups: the case with ISR (n=40) and control without ISR after 6 months from stenting (n=51). The case and control groups were matched in terms of age and sex matching. The genotypes of the G22A variant in the samples were examined by the molecular method of PCR-RFLP and electrophoresis and the results were statistically analyzed by using t-test. The results of this study show that the frequency of allele A of variant G22A in (+ ISR) group is higher than (- ISR). However, there is no significant relationship between the distribution of allele and genotype frequency of this variant with the incidence of ISR (p>0.05).","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72584210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of self-hypnosis on the experience of delivery fear and duration of labor in primiparity: A randomized clinical trial","authors":"B. Kamalimanesh, M. Moradi, M. Fathi, Maliheh Afiat, Mahnaz, Boroumand Rezazadeh, M. Shakeri","doi":"10.32592/jbirjandunivmedsci.2021.28.1.101","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2021.28.1.101","url":null,"abstract":"Background and Aims: Fear of delivery in females can lead to negative side effects, such as the experience of long and hard labor. Reduction of delivery fear is one of the goals of natural delivery program, and hypnosis has been considered a way to reduce this fear. With regard to the contradictory results of the studies in this field, this study aimed to determine the effect of self-hypnosis on the experience of delivery fear and duration of labor in primiparity.\u0000Materials and Methods: This clinical trial was conducted on 63 pregnant women who were divided into self-hypnosis (n=30) and control groups (n=33) using a blocking method in Mashhad, Iran, during 2019. The intervention group received two sessions of hypnosis at 37th and 38th weeks of pregnancy which consisted of listening to an audio file until delivery time. On the other hand, the control group received only the routine care. Fear was evaluated at 37th week of pregnancy and 24 h after delivery. Data were analyzed using SPSS software (version 16), and a p-value less than 0.05 was considered statistically significant.\u0000Results: The mean scores of delivery fear experience (P<0.001), as well as the duration of the second stage (P=0.013) and third stage of labor (P=0.009) were significantly lower in the self-hypnosis group, compared to the controls.\u0000Conclusion: Self-hypnosis was effective in reducing the experience of delivery fear and duration of the second and third stages of labor in primiparity. Therefore, self-hypnosis is recommended to reduce the experience of delivery fear and duration of the second and third stages of labor in primiparity.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83927108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone biochemical marker response to a plyometric exercise session with and without blood flow restriction in inactive adolescent females","authors":"Fatemeh Fakhri, A. Habibi, M. Ghanbarzadeh, R. Ranjbar","doi":"10.32592/jbirjandunivmedsci.2021.28.1.102","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2021.28.1.102","url":null,"abstract":"Background and Aims: Physical activity and blood flow restriction (BFR) training can affect bone metabolism. This study aimed to investigate the effect of a plyometric exercise session with and without blood flow restriction on bone metabolism markers, such as bone alkaline phosphatase (BALP) and C-terminal telopeptide of type 1collagen (CTX), as the markers of bone formation and destruction, respectively, among inactive adolescent females.\u0000Materials and Methods: This study was conducted using a quasi-experimental design with pretest-posttest. The participants (n=48) were randomly divided into four groups of high-intensity training (n=12), low-intensity training (n=12), low-intensity training+restricted blood flow (n=12), and control (n=12). The training protocol included 68 jumping movements. The intensity of the exercise was less than two and more than four times the body weight for low intensity groups with and without obstruction and the high-intensity group, respectively. Blood samples were taken before and immediately after the exercise to evaluate BALP and CTX. Data analysis was performed using dependent t-test and one-way ANOVA. A p-value of ≤0.05 was considered statistically significant.\u0000Results: A significant decrease was observed in CTX serum levels in high-intensity exercise group (P=0.04) and low-intensity exercise group with limited blood flow (P=0.03), compared to those in the pre-test. However, there was no significant within-group and intergroup changes in serum levels of bone formation marker (P≥0.05).\u0000Conclusion: According to the results, a low-intensity plyometric exercise session with blood BFR can be as effective as high-intensity plyometric exercises in altering bone metabolism (reducing bone absorption marker).","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72530772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the effect of levofloxacin-based three-drug regimen with clarithromycin-based four-drug regimen in the treatment of Helicobacter pylori infection in Birjand: Short Communication","authors":"Fatemeh Abasnia, T. Fakharian, F. Salmany","doi":"10.32592/jbirjandunivmedsci.2021.28.2.108","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2021.28.2.108","url":null,"abstract":"Given the high prevalence of Helicobacter pylori infection in Iran, eradicating it with an effective, low-cost, and easy diet is one of the challenges ahead The aim of this study was designed to compare the effect of \"levofloxacin-based regimen “with” clarithromycin-based regimen” in the treatment of Helicobacter pylori. This quasi-experimental study was performed on 161 patients with Helicobacter pylori infection referred to the gastrointestinal clinic of Vali-asr Hospital in Birjand. Patients were randomly divided into two groups A (levofloxacin, pantoprazole and amoxicillin) and B (amoxicillin, pantoprazole, clarithromycin and bismuth sub citrate) and were treated for 14 days. 4 weeks after the end of treatment, the urease breath test was performed to check for eradication In levofloxacin group, 67 patients (91.8%) and in clarithromycin group 55 patients (70.5%), eradication was performed which was statistically significant. (p=0.001). Also, there was no statistically significant difference between the two groups in terms of complications (p=0.3). The results showed that the levofloxacin-based regimen could be used as an alternative to four clarithromycin-based therapies due to its greater efficacy in eradicating Helicobacter pylori despite the lower number of drugs and similar side effects.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74508612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Density of bacterial particles cultivable in the air of inside and outside kindergartens in Birjand in 2019","authors":"","doi":"10.32592/jbirjandunivmedsci.2020.27.4.106","DOIUrl":"https://doi.org/10.32592/jbirjandunivmedsci.2020.27.4.106","url":null,"abstract":"Background and Aim: Bioaerosols are airborne particles that contain bacteria, viruses and fungi. Human reaction to bioaerosols is very different. The aim of this study was performed to determine the density of bacterial particles cultivable in the air of inside and outside kindergartens in Birjand.\u0000Materials and Methods: This descriptive-analytical cross-sectional study was performed. Birjand city was divided into 5 regions based on geographical location and 6 kindergartens were randomly selected. Sampling was done in the morning shift from 6 selected kindergartens.The culture medium used was triptic soy agar for bacteria. Sampling was performed at a flow rate of 28.3 L/Min in 35 minutes at a distance of 0.8 to 1 M above the ground in the center of each class. Statistical analysis was performed using SPSS (Version.16) software and Mann-Whitney and Kruskal-Wallis statistical tests and a significance level (P<0.05) was considered.\u0000Results: The results showed that the highest mean bacterial microbial load in February was (3.83±8.04) CFU/m3 and suspended particles in March (196.13±382.54) CFU/m3. There was no significant relationship between bacterial density with suspended particles and temperature (P>0.05). There was a significant relationship between bacterial density and total suspended particles (P<0.05). There was a significant relationship between the amount of suspended particles (PM1, PM2.5, PM10) with the environment inside and outside the kindergarten (P<0.05).\u0000Conclusion: From the findings of this study, the concentration of bacterial contamination in terms of quantity and type of identified species and the amount of airborne particles can be identified to prevent adverse health effects.","PeriodicalId":31015,"journal":{"name":"Journal of Birjand University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85004672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}