South Asian Research Journal of Applied Medical Sciences最新文献

{"title":"Contribution of Three-Dimensional Transesophageal Echocardiography in the Assessment of Atrial Septal Defects (ASD)","authors":"H. Kalkoul, S. Lehachi, H. Zitouni, M. Chettibi","doi":"10.36346/sarjams.2023.v05i04.006","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i04.006","url":null,"abstract":"The article examines the contribution of real-time three-dimensional transesophageal echocardiography (3D TEE) in the assessment of ostium secundum atrial septal defects (ASD) in adults. 3D TEE provides a precise and comprehensive view of cardiac anatomy, enabling the evaluation of size, shape, and border quality of the ASD. In a series of 27 cases, 3D TEE demonstrated a strong correlation between 3D-measured ASD parameters and the size of the closure device required. This technique is crucial for accurate pre-interventional evaluation, enhancing the success and safety of percutaneous or surgical interventions for ostium secundum ASD. Three-dimensional transesophageal echocardiography represents a significant advancement in cardiovascular imaging for complex structural heart abnormalities.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134206238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spontaneous Skin Infection Secondary to Mycobacterium abscessus Var Massiliense in An Immunocompetent Patient","authors":"Pérez-Campos Laura Areli, P. E, Olmedo-Reneaum Alejandro, Molina-Jaimes Aaron","doi":"10.36346/sarjams.2023.v05i04.003","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i04.003","url":null,"abstract":"M. abscessus var. abscessus and M. abscessus var. massiliense are fast growing non-tuberculous mycobacteria that cause skin and soft tissue infections. We present a 32-year-old female that initiated her current condition two years ago prior her medical assessment due to an event of cellulitis in the front part of her legs and later on being in contact with contaminated water. Two weeks later after the exposure she developed a dermatosis in the same region characterized by disabling pain, intermittent fever and edema without achieving improvement after being treated with multiple topic treatments. For these reasons, extension studies were carried out to get to the diagnosis of infection related to Mycobacterium abscessus var. massiliense, this gave the opportunity to give a successful therapeutic approach. Finally, after being treated for a month, an adequate evolution was obtained.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134407611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fissural Pleural Effusion Presenting As ‘Pseudotumor Lung, Phantom Tumour or Round Pneumonia’ In Primary Pulmonary Tuberculosis: Bronchoscopy is Point of Care Test in Presence of Satellite Nodules in Chest Imaging!","authors":"S. Patil, M. Mirza, Swati V. Patil","doi":"10.36346/sarjams.2023.v05i04.004","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i04.004","url":null,"abstract":"Pulmonary Tuberculosis has diverse radiological presentations such as consolidation, cavitation, airway disease, pleural effusion and lymphadenopathy. Pneumonia-like presentation in tuberculosis is very commonly reported in Pulmonary Tuberculosis. Fissural effusion is common in cardiac failure and isolated fissural effusion is rarely described in literature with etiology as tuberculosis. Round pneumonia is commonly described in pediatric cases with community acquired pneumonia and also frequently reported in childhood pulmonary tuberculosis. Round pneumonia is very infrequently reported in adults with pneumonia and to very few published data as due to tuberculosis. In this case report, a 21-year female, presented with constitutional symptoms for 3 months duration with partial response to medical treatment received in line with pneumonia, bronchial asthma and bronchitis. Radiological investigations documented round opacity in right mid-zone with no adventitious breath sound on clinical examination. Recurrent, progressive and partially responding constitutional symptoms was the reason for referral to our center. We have further evaluated with HRCT thorax and documented loculated right horizontal fissural effusion with subpleural parenchymal opacity in right upper lobe posterior segment and right middle lobe lateral basal segment with peri-consolidation satellite nodules in right posterior segment. We have done bronchoscopy due to negative induced sputum microbiological workup. Bronchoscopy guided BAL microbiological workup documented MTB genome with rifampicin sensitivity in cartridge based nucleic acid amplification test and negative BAL smear for AFB. Treatment initiated with anti-tuberculosis (ATT) and recorded near complete radiological resolution, bacteriological cure after six months with good compliance. High index of suspicion is required while managing these cases with constitutional symptoms and typical radiological features such as ‘round pneumonia or fissural effusion’ in absence of other causes for the same. Fissural effusion or round pneumonia due to tuberculosis is rare in adults but not uncommon. Bronchoscopy is a gold standard test to confirm etiological diagnosis due inadequate or poor quality of induced sputum sample in cases with round pneumonia and fissural effusion. Isolated Fissural effusion secondary to pulmonary tuberculosis is extremely rare in medical literature and this will be first case reported till date.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127921818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Epirubicin, Cyclophosphamide and Paclitaxel-based Chemotherapy Response for Treatment of Breast Cancer Patients as Neo-Adjuvant: A Case-Series in a Tertiary Care Hospital in Bangladesh","authors":"Lt. Col. Dr. Fatima Sarkar, Dr. Col. S.M. Rahid Sarwar, Major. Dr. Tarik Hasan, Dr. Tarim Mahmood, Dr. Tasnim Mahmud","doi":"10.36346/sarjams.2023.v05i04.002","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i04.002","url":null,"abstract":"Background: Breast cancer is the most common cancer among women across the world. Various treatment modalities in terms of radiotherapy, chemotherapy or surgery along with several neoadjuvant or adjuvant therapies are already established for the better survival of the patients. New modalities are still under research every other day for improvement of quality of life of cancer victims. Objective: This case series was conducted to assess the efficacy and safety profile of primary breast cancer patients by adding Paclitaxel to the established regimen of Epirubicin and Cyclophosphamide. Methods: This was performed during January 2019 to January 2021 with 9 cases of clinically diagnosed breast cancer patients at Combined Military Hospital, Dhaka. Patients included in our study received Epirubicin in the dose of 75-100 mg/m2 dl, Cyclophosphamide 600 mg/m2 dl, every 3 weeks for a total of 4 cycles followed by Paclitaxel at a dose of 175 mg/m2, every 3 weeks for a sum of 4 cycles. After every cycle of neoadjuvant chemotherapy and at the end of it, response was assessed by ultrasound. Results: The findings revealed 6 out of 9 patients showed pathological complete response at the end of this neoadjuvant regimen. The remaining 3 cases showed partial response. Toxicity was minimal and well-managed. 5 patients developed leukopenia in terms of haematological events, whereas for other effects, nausea and fatigue was commonly encountered. Conclusion: Overall, this treatment modality turned out to be feasible and a good option for neoadjuvant therapy in terms of efficacy and safety profile for the breast cancer patients.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115166523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Stress and Sleep Disorders among Medical Students at Al-Kindy College of Medicine and its impact on Academic Performance","authors":"Israa Mohammad Abd AL- Khaliq, Zubaida Najim Abdullah, Jahan Abduljabar Abdullah, Zahraa Adnan Mohammed","doi":"10.36346/sarjams.2023.v05i04.001","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i04.001","url":null,"abstract":"Introduction: Sleep, an essential therapeutic part of human physiology, Sleep problems was widespread among students in medical colleges, and excessive stress and the pressure of holding grades can affect their sleep quality. The relationship between sleep, stress and cognition/learning is far more complex than perceived. Material and Method: Cross sectional study was conducted in Al-Kindy College of Medicine, during the period from (2022 to 2023) academic year. The electronic questionnaire was distributed among all students. Analysis of data was carried out using IBM SPSS version 24. Results: A total of (500) medical students' online surveys were analyzed from AL-Kindy College of Medicine, The highest number of participants was from the fifth year with (114) students, and percentage of (22.8%), whereas the lowest number of participants was from the second year with (68) students (13.6%). There were about (258) male with percentage of (51.6%), and (242) female with percentage of (48.4) participated in this study. The majority of students (160) with percentage of (32%) were sleeping (6) hours/day, and a minority (1) student with percentage of (0.2%) had 3 hours sleeping/day. There was a significant relationship between sleep hours and sleep deprivation like, about (297) students, with prevalence of (59.4%) agreed that sleeplessness negatively affected their academic performance, while (41) students with percentage of (8.2%) disagreed. According to the effect of stress, the prevalence of sleep disorders among undergraduate medical students was shown that (169) students with percentage of (33.8%), were always stressed, while (34) students with percentage of (6.8 %), were rarely affected by stress. According to the causes of stress, the majority of students (198), with percentage of (39.6%), were had too much study, while (1) student, with percentage of (0.2%), was had no significant reason. Other (174) students, with percentage of (34.8%), were under stress because of exams and (127) students, with percentage of (25.4%), were under stress because of life events. Conclusions: Sleep disorders are common among medical students. The study also reveals that there is a strong, positive and significant relationship between stress levels sources of stress and sleep deprivation which is associated with poor academic performance. Recommendations: Keeping bedtime and wake time consistent, including on weekends. Regular activity helps promote a good night's sleep. Also schedule exercise at least a few hours before bedtime and avoid stimulating activities before bedtime. Further research is required in this field.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115388564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studying the Antibacterial and Insecticidal Properties of Rosemary Extract by Iron Nanoparticles Prepared by Using Ultrasound","authors":"S. Ahmed, R. Hameed, A. M. Yousif, Zena Hassan Jazar","doi":"10.36346/sarjams.2023.v05i02.001","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i02.001","url":null,"abstract":"The green plant-mediated synthesis of iron nanoparticles (GPS-Fe) nanoparticles (NPs) has become more and more popular. In this study, fresh rosemary leaf aqueous extracts that decreased aqueous silver nitrate were used to demonstrate the synthesis of FeNPs. This procedure allowed for the synthesis of NPs that were examined using a different of analytical techniques, including transmission electron microscopy (SEM), energy-dispersive X-ray spectroscopy, FTIR, ultraviolet-visible (UV-Vis) spectrophotometry, and studies on dynamic light scattering. According to ocular observation and UV-Vis spectra, fresh leaf extract treatment changed the color of aqueous ferric nitrate to a bluish hue. Additionally, the TEM analysis revealed that the synthesized NPs were evenly dispersed and had average sizes less than 65 nm. Meanwhile, the bioactivity test shows that the NPs had an inhibitory effect on a number of pathogenic bacteria and caused a high rate of mortality in three stages of house fly larvae.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117311174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Literacy: The Most Neglected Essential Human Quality","authors":"Abdul Kader Mohiuddin","doi":"10.36346/sarjams.2023.v05i01.002","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i01.002","url":null,"abstract":"People must have particular personality traits and social resources, also known as health literacy, in order to access, comprehend, and use information to make decisions about their health. Patients' ability to engage in complex disease management and self-care is strongly related to their level of health literacy. It can help us stay healthy by preventing illness and effectively managing existing illnesses. People with low health literacy (LHL) may find it difficult to manage their condition and prevent illness, which may lead to increased use of healthcare services. Furthermore, LHL is associated with increased hospitalizations, increased use of emergency care, decreased use of preventative services, and a worsened ability to understand labels and health messages, a worsened state of health, higher mortality, and more expensive medical care.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134200499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances and Challenges in Stem Cell Culture","authors":"Khadeeja Khadeeja, Muhammad Imran, Muhammad Naeem, A. Maria, Arooj Anwar, Iqra Tariq, M. Saleem, Urwa Iftikhar, Muhammad Sharjeel, Nimra shabbier Hussain, Muhammad Amar, M. Mazhar","doi":"10.36346/sarjams.2023.v05i01.001","DOIUrl":"https://doi.org/10.36346/sarjams.2023.v05i01.001","url":null,"abstract":"In recent years, stem cell therapy has become a very promising and complex scientific research topic. In the body, stem cells have the capacity to differentiate into a wide variety of cell types. They are capable to regenerate body system. Adult stem cells and embryonic stem cells are the two primary categories of stem cells. Through cell- replacement therapies, stem cell-based therapies can give the opportunity to replace lost, damaged, or old cells in order to regenerate or repair tissues and organs. Additionally, using genetically altered stem cells as delivery systems holds enormous potential for treating inherited genetic flaws and delivering therapeutic chemicals to specifically injured tissues and organs. The ensuing integration of science and medicine made possible by more research will enable the therapeutic application of ES cell technology. In the end, such a program might present a remarkable new weapon in the fight against human sickness.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133737355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Guided Injections in Shoulder as Compared to Direct Injections","authors":"Dr.Anil Batta, Umesh Kumar, Preeti Sharma","doi":"10.36346/sarjams.2022.v04i05.004","DOIUrl":"https://doi.org/10.36346/sarjams.2022.v04i05.004","url":null,"abstract":"Ultrasound, also known as sonography, is an imaging method that uses high-frequency sound waves to produce real-time and dynamic images of the body. Ultrasound is increasingly being used to assist Sports Medicine Physicians, Rheumatologists, Orthopedists, and Primary Care. Procedural planning prior to any procedure increases efficiency in the operative field and reduces patient discomfort. Ultrasound is commonly utilized in regenerative medicine techniques due to the ability to visualize soft tissue targets with high resolution. Ultrasound is beneficial in both diagnostic purposes and image-guidance for procedures. Understanding how to quickly optimize the ultrasound image and ergonomics for the procedure will greatly improve your procedure workflow.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116715078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Biomarkers in Patients of ACS","authors":"Dr.Anil Batta, U. Kumar, Preeti Sharma","doi":"10.36346/sarjams.2022.v04i05.003","DOIUrl":"https://doi.org/10.36346/sarjams.2022.v04i05.003","url":null,"abstract":"Millions of patients present annually with chest pain, but only 10% to 15% have myocardial infarction. Lack of diagnostic sensitivity and specificity of clinical and conventional markers prevents or delays treatment and leads to unnecessary costly admissions. Comparative data are lacking on the new markers, yet using all of them is inappropriate and expensive. The older markers like aspartate amino-transferase, creatine kinase, lactate dehydrogenase etc. lost their utility due to lack of specificity and limited sensitivities. Cardiac troponin levels but negative CK-MB who were formerly diagnosed with unstable angina or minor myocardial injury is now reclassified as non–ST-segment elevation MI (NSTEMI) even in the absence of diagnostic ECG changes. CK-MB is both a sensitive and specific marker for myocardial infarction. Cardiac troponin T is a cardio-specific, highly sensitive marker for myocardial damage. Cardiac troponin I is a contractile protein exclusively present in the cardiac muscle. The absolute cardiospecificity of cTnI allows the diagnosis of myocardial infarction distinct from muscle lesions and non-cardiac surgery.","PeriodicalId":309690,"journal":{"name":"South Asian Research Journal of Applied Medical Sciences","volume":"401 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114930672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}