New Frontiers in Medicine and Medical Research Vol. 5最新文献

{"title":"Determination of Correlation of Body Mass Index and Waist Hip Ratio with Cardiovascular Parameters in Sedentary Males","authors":"M. Jayalakshmi","doi":"10.9734/bpi/nfmmr/v5/1814c","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/1814c","url":null,"abstract":"Background: There is an excess of adipose tissue accumulation in obesity which is associated with more sympathetic activity resulting major potential mechanism contributing to increased risk of cardiovascular complications. Obesity is associated with coronary arterial diseases, type-2 diabetes mellitus, infertility, osteoarthritis, and colo-rectal cancers. Visceral fat is more atherogenic. \u0000Methods: 100 sedentary healthy male subjects selected randomly in the general population of Davangere city. Anthropometric parameters like weight, height, waist and hip circumference were measured. With these, Body Mass Index (BMI), Waist Hip Ratio (WHR) were calculated. Correlation between BMI and WHR with cardiovascular parameters was made. \u0000Objectives: To determine body mass index, waist hip ratio and cardiovascular parameters in sedentar Subjects. \u0000To correlate body mass index, waist hip ratio with cardiovascular parameters in sedentary Subjects. \u0000Results: There was statistically significant increase in body mass index, waist hip ratio, blood pressure and pulse rate was seen and there was positive correlation between body mass index, waist hip ratio with blood pressure and pulse rate in sedentary subjects. \u0000Conclusion: Sedentary life style and obesity are associated with increase in body mass index, waist hip ratio, blood pressure and pulse rate. There is a positive correlation between Body Mass Index, Waist Hip Ratio with Pulse Rate, Systolic and Diastolic Blood Pressure.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130510382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibiotics Impact on Mitochondria Result in Potential Contributions to Carcinogenesis, Coronary pathology, other Medical Conditions and Ecosystem Risks","authors":"Jorma Jyrkkanen","doi":"10.9734/bpi/nfmmr/v5/11590d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/11590d","url":null,"abstract":"With the discovery by Calghatgi [1] that three common antibiotics (Abs) increased mitochondrial reactive oxygen (ROS) and lipid peroxide (LP) and depleted their natural absorbant glutathione led me to investigate further the potential impacts of these genotoxic substances on carcinogenesis. The range of impacts on mitochondria and cellular DNA varied by antibiotic to those consistent with known prior contributions to carcinogenesis. Specific cancers probably increased by these changes were HCC, RCC (KCC), CRC, cancer of the esophagus. Tumor suppressor gene mutations resulting from LP were noteworthy in this regard and mutations induced in CRC were consistent with those found in carcinogenesis of CRC. In addition depression of short chain fatty acids in microbiomes were found which depress the immune system increasing risk of all cancers. Many cancers were increased according to epidemiological studies linking Abs with elevated odds ratios, with one concern in particular, fatal breast cancer. The impact of loss of functionality of the mitochondria was also linked to depression of the citric acid cycle and therefore ATP which deflected metabolism to glycolysis, the Warburg mechanism, also increasing risk of all cancers, favored by cancer cells. In conclusion, some portion of many cancer types are probably increased in likelihood by number, type and frequency of Abs treatment and chronic residue exposure which varies from individual to individual. This led me to propose a three pronged carcinogenesis mechanism for Abs. 1. Cancer critical mutations 2. Immune depression 3. loss of mitochondrial functionality leading to Warburg effects. Damage to mitochondria were also noted by common pesticides tested in China and more recently by covid spike protein [2] and cancer associations were also found for many pesticides supporting a similar contributory etiology. Heart health concerns were raised by these findings because of the myriad mitochondria in the heart and because of long term reliability needs. Studies suggesting hearts were affected by Abs and pesticide exposure were presented. Because of their geographical ubiquitousness and the huge range of diseases associated with mitochondrial dysfunction, antibiotics and pesticides and bacteriacidal biocides are of concern for biodiversity and life in general. I propose research steps to evaluate antibiotic safety and suggest directions for further research and make suggestions on ways to ameliorate Abs toxicity.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127618982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"‘Research on Clinical Significance of Blood groups on Bleeding time and Clotting Time and its Association with Diseases; An Advanced Study’","authors":"M. Geetha, J. J. Benjamin","doi":"10.9734/bpi/nfmmr/v5/3653f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/3653f","url":null,"abstract":"Background: Blood group plays a unique role in revealing the identity of an individual. Studies have shown that certain diseases and personality features vary among ABO blood groups. In addition, variations in terms of bleeding tendencies among these blood groups have also been unleashed. Hence a study was done to the find association of bleeding time (BT) and clotting time (CT) with ABO blood group. \u0000Methods and Materials: This study had a cross-sectional study design and was done among 250 young adults aged between 18 and 24 years. Slide agglutination method was used to assess ABO blood group; while Dukes and capillary tube method were used to determine BT and CT respectively. \u0000Statistical Analysis: Chi-square analysis was done to analyze the association of BT and CT with blood group. Statistical significance was considered when p value was less than 0.05. \u0000Aim & Objectives: To determine the predominant ABO blood group  among the young adult population and  to find the association between ABO blood group  with bleeding time and clotting time and to assess the gender variation  in bleeding time and clotting time among the young adult population. \u0000Conclusion: In this study, results have shown that blood group O was the predominant blood group among the study population and blood group O and B had prolonged BT and CT compared to other groups. Based on gender, females had higher CT compared to males.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"14 35","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114044487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Influence of Age and Regular Exercise on Blood Pressure in Males","authors":"M. Jayalakshmi, Chandrashekhar","doi":"10.9734/bpi/nfmmr/v5/1813c","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/1813c","url":null,"abstract":"Background: Both cross-sectional and longitudinal epidemiological studies have shown that sedentary life style elevates blood pressure and increased risk of hypertension and pre-hypertension among subjects with sedentary lifestyle. Sedentary life style increase the propensity to age related diseases and premature deaths. Inactivity may diminish life expectancy not only by predisposing to age related diseases but also it may influence the aging process itself by oxidative stress. \u0000Objectives: To determine the influence age and exercise on blood pressure in sedentary and non sedentary subjects. \u0000To compare the parameters between sedentary and non sedentary subjects. \u0000Methods: 100 male healthy sedentary and non-sedentary subjects in the age group of 25-55 years were selected randomly from the general population of Gadag city. Depending upon the age, subjects were divided into three groups for analysis. Blood pressure was recorded and compared between three groups. \u0000Results: Statistically significant increase in blood pressure in sedentary subjects and also in group two and three compared to group one which shows age factor is also important in developing hypertension.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134224054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Patient-Physician Relationship and Ante-natal Seeking Behaviour in Public Hospitals, Ogun State, Nigeria","authors":"S. Aluko-Arowolo, M. Thomas, O. Ayobami","doi":"10.9734/bpi/nfmmr/v5/6691d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/6691d","url":null,"abstract":"The role of the patient-physician relationship as an underpinning factor that may inhibit or stimulate early pregnancy booking among women in Ijebu, Ogun State, was investigated in this study. The study used a survey and an in-depth interview as part of a triangulation strategy. Ijebu-Ode accounted for 32.2 % (141) of the whole sample, whereas Ijebu-Igbo accounted for 64.8% (259) of the total sample. A structured questionnaire was given to 400 consenting women who were attending ante-natal clinics (ANC) sessions in hospitals in Ijebu-Ode and Ijebu-Igbo who were chosen at random. Furthermore, a stratified sampling procedure was used to choose ten percent of the women for in-depth interviews. In addition, ten in-depth interviews (IDIs) with gynaecologists, nurses, and other health care professionals were undertaken. The study discovered a non-cordial relationship between physicians and antenatal patients, which contributes to late pregnancy booking and inconsistent ANC attendance by pregnant women. Many pregnant women avoid ANC because of the physician's uncooperative style, which includes not paying enough attention and using aggressive, unclear, and ambiguous language that are incomprehensible to patients who are hardly literate. According to the findings, women's early pregnancy booking may be influenced by their proximity and reciprocal relationship with their doctor. As a result, it is recommended that physicians pay close attention to their patient relationships, and that appropriate government, agency, and non-governmental organisations (NGOs) foster the transmission of maternal health education.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128319744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Complicated Childbirth Aid Protocol Inspired by Luba-Kasai Therapeutic Practice","authors":"A. Mamba","doi":"10.9734/bpi/nfmmr/v5/1828c","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/1828c","url":null,"abstract":"Improved maternal health remains a major concern of the United Nations in general and of the World Health Organization in particular, which have placed an important place on the Millennium Development Goals (MDGs) as well as in the objectives for Sustainable Development (SDO). Curiously, among the causes of complications of childbirth and pregnancy, the emphasis is more on physiological than psychosocial deaths, whereas in our least developed countries, where the percentage of maternal is mortality, cultural and psychological problems expose women to unwanted pregnancies and psychic traumas that manifest themselves during parturition in the form of eclampsia, haemorrhage and work defects, thus leading the woman and her baby to the risk of death. In the present work, we have proposed a protocol to help childbirth, inspired by the therapeutic practices of our African cultures. Indeed, our ancestors were able to solve the complications of childbirth by speech. The interview with woman with complications around her life and relationships triggered a kind of catharsis in the latter, the labor of childbirth was normal again and the delivery was normal. The protocol comprises three components: psychodynamic interview, prophylactic psychoeducation, psychological support. This protocol is based on the humanistic theories of Carl Rogers and Maslow and the sophrology of Alfonso Caycedo and consists in subjecting the parturient to a relaxation exercise by alternate breaths and haptonomy in a helping relationship to allow communication between the woman and her child who is to be born. This study will have the merits of integrating our complicated childbirth assistance protocol into the psychotherapy arsenal already in place, in order to rightly improve maternal health in childbirth.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"180 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124141697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miniscrews Anchorage for Distalization of Maxillary Molars","authors":"A. Houb-Dine, F. Zaoui","doi":"10.9734/bpi/nfmmr/v5/3449f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/3449f","url":null,"abstract":"Miniscrew has greatly revolutionized the clinical and biomechanical approach of anchoring in orthodontics. Used as direct or indirect anchoring, the orthodontic miniscrews indications field is expanding due to their easy insertion, and their immediate loading ensuring an absolute anchoring. Our objective through this clinical case is to show the effectiveness of these miniscrews in the correction of the uncontrolled loss of anchoring.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"65 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133724249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}