‘Research on Clinical Significance of Blood groups on Bleeding time and Clotting Time and its Association with Diseases; An Advanced Study’

M. Geetha, J. J. Benjamin
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Abstract

Background: Blood group plays a unique role in revealing the identity of an individual. Studies have shown that certain diseases and personality features vary among ABO blood groups. In addition, variations in terms of bleeding tendencies among these blood groups have also been unleashed. Hence a study was done to the find association of bleeding time (BT) and clotting time (CT) with ABO blood group. Methods and Materials: This study had a cross-sectional study design and was done among 250 young adults aged between 18 and 24 years. Slide agglutination method was used to assess ABO blood group; while Dukes and capillary tube method were used to determine BT and CT respectively. Statistical Analysis: Chi-square analysis was done to analyze the association of BT and CT with blood group. Statistical significance was considered when p value was less than 0.05. Aim & Objectives: To determine the predominant ABO blood group  among the young adult population and  to find the association between ABO blood group  with bleeding time and clotting time and to assess the gender variation  in bleeding time and clotting time among the young adult population. Conclusion: In this study, results have shown that blood group O was the predominant blood group among the study population and blood group O and B had prolonged BT and CT compared to other groups. Based on gender, females had higher CT compared to males.
血型对出血时间和凝血时间的临床意义及其与疾病关系的研究高级研究”
背景:血型在揭示一个人的身份方面起着独特的作用。研究表明,某些疾病和人格特征在ABO血型之间存在差异。此外,这些血型之间在出血倾向方面也存在差异。因此,研究发现出血时间(BT)和凝血时间(CT)与ABO血型的关系。方法与材料:本研究采用横断面研究设计,在250名年龄在18 - 24岁的年轻人中进行。采用玻片凝集法测定ABO血型;分别采用Dukes法和毛细管法测定BT和CT。统计学分析:采用卡方分析分析BT、CT与血型的相关性。当p值小于0.05时,认为差异有统计学意义。目的:确定青壮年人群中主要的ABO血型,发现ABO血型与出血时间和凝血时间的关系,评价青壮年人群中出血时间和凝血时间的性别差异。结论:本研究结果显示,O型血是研究人群中的优势血型,与其他血型相比,O型血和B型血的BT和CT延长。从性别上看,女性CT值高于男性。
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