New Frontiers in Medicine and Medical Research Vol. 5最新文献

{"title":"Study of Fingerprint Patterns in Relation to Gender and Blood Groups in Navi Mumbai, India","authors":"Amit Patil, Amrit A Malik, Treza Shirole","doi":"10.9734/bpi/nfmmr/v5/3498f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/3498f","url":null,"abstract":"Introduction: Human identification can be made by using various physical and mental characteristics. Being unique, fingerprints can be used to identify an individual. The fingerprint is a greasy and oily impression of the friction ridges of the finger. A strong correlation has been found in earlier studies between the fingerprint pattern and gender and blood group. \u0000Objectives: The objective of the study was to determine the correlation (if any) between the fingerprint pattern and blood group and gender. \u0000Materials and Methods: The study was conducted on 170 subjects [70 males and 100 females] in the age group of 18-65 years. The fingerprint pattern of the study participants was compared with the gender and ABO-Rh blood group after taking their verbal consent. \u0000Results: Amongst the ABO blood group, the most common blood group was B (36.47%), followed by O (35.88%), A (18.23%) and AB (9.4%). Rh + ve was the most common rhesus factor (95.88%). The loop was the most common pattern (62.35%), followed by whorl (32.94%) and arch (4.7%). There was a significant association between the fingerprint pattern and the ABO blood group (P-value < 0.05). \u0000Conclusion: The present study confirms that loop is the most common fingerprint pattern while arch was the least common. The study revealed a significant association between the fingerprint pattern and the ABO blood group. No statistically significant association was found between the fingerprint pattern and gender.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130502129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Role of CECT Abdomen in Intestinal Obstruction: A Clinical Approach","authors":"M. F. G. Dudhwala","doi":"10.9734/bpi/nfmmr/v5/10998d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/10998d","url":null,"abstract":"Background: Intestinal obstruction, which can be either dynamic or adynamic, is a common clinical event. To avoid missing strangulation, the old adage \"Never let the sun set or dawn on a clogged bowel\" was taught. With its multiplanar reformatted imaging, helical CT can properly define the level, degree, origin, and problems associated with obstruction. \u0000Aim: Aim of the study was to depict the spectrum of MDCT findings in cases of small and large bowel obstruction and correlation of CT scan with intraoperative findings and the cause of intestinal obstruction. \u0000Methods: Contrast enhanced MDCT examination of 50 patients were prospectively included in the study who had evidence of clinical as well as MDCT evidence of bowel obstruction and in whom surgical/clinical follow-up for final diagnosis was available. CT scan was done in all the patients with MDCT (Brightspeed GE 16 slice system). The axial sections were reconstructed in coronal and saggital planes to determine site and cause of bowel obstruction. \u0000Results: The commonest cause of intestinal obstruction in adults in this study series was adhesions/bands in 38% cases. Out of 47 operated patients for intestinal obstruction, CT findings matched with intraoperative findings in 43 patients (91%) whereas cause of intestinal obstruction matched with CT findings in 37 patients (74%). \u0000Conclusions: Management decisions in intestinal obstruction remain notoriously difficult, relying on a combination of clinical, laboratory, and imaging factors to help stratify patients into conservative or surgical treatment. CT in these patients can help surgeon to go for surgery early and prevent complications.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127487976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Angle of Anterior Chamber with SD-OCT in Patients Presenting to Tertiary Health Care Center: A Cross-sectional Study","authors":"N. Khan, Saroj Gupta, P. Agrawal","doi":"10.9734/bpi/nfmmr/v5/11637d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/11637d","url":null,"abstract":"Purpose: To evaluate the normative data of anterior chamber angle in patients presenting to tertiary health care center using anterior segment spectral domain OCT (ASOCT) in central Indian. \u0000Design: 120 Consecutive patients presenting to ophthalmology out patient department of tertiary health care center were enrolled in a cross-sectional study. \u0000Methods:All patients underwent comprehensive ocular examination. Ocular examination included best corrected visual acuity, refraction, anterior segment examination by slit lamp, fundus examination, gonioscopy by 3 mirror Goldmann contact lens, IOP measured by Goldmann applanation tonometer, OCT analysis of angle of AC .The duration of study was one year six months. This study was approved from the research and ethics committee of the institute. Informed consent was obtained. Data was analyzed by using SPSS 16.0 \u0000Results: In our study we have studied the AS-OCT parameters among normal subjects and results of 120 subjects were analyzed. It is noted that mean nasal & temporal AOD was less in females (0.4175 µm, 0.4613 µm) as compared to males (0.4583 µm, 0.4142 µm).This study found that older people had a narrower anterior chamber angle (measured in degrees) and shallower ACD (measured in millimeters). \u0000Conclusion: Our study is the first study in central India done with SD-OCT to give normative data of anterior chamber parameters among normal subjects. These normative values will help us identify patients with abnormal values signifying anterior chamber abnormalities.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"106 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131950782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on Chronic Pain Management in Roman Coloniae","authors":"Valentine J. Belfiglio","doi":"10.9734/bpi/nfmmr/v5/11663d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/11663d","url":null,"abstract":"The presented study discusses the use of analgesics by medical personnel in the colonies and at field hospitals located in the urban capitals of the colonies was an important aspect of providing immediate care to Roman veterans after injuries or other causes of chronic pain. Upon completion of twenty years or more of active military service, Roman legionnaires received financial benefits from the Roman State and free plots of land in Italy or Roman conquered lands. These outposts in Roman conquered territory served as a buffer between the Roman State and potential Roman enemies, helped to suppress insurrections in the territories they occupied and helped to Romanize these territories. The coloniae varied in size and population from a few hundred to several thousand people. Adequate medical care is indispensable to the survival and prosperity of any community of people. The larger coloniae had hospitals and health care professionals to support the colonists living there. Smaller colonies had a medical clinic with a smaller staff. Managing chronic pain suffered by ranchers and farmers was a major concern for the medici (physicians) who lived and worked in the coloniae. The veterans and their families sometimes required pain management for their functionality and quality of life.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114413378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study on the Altered Gonadal Expression Levels of the Adipokine Lipocalin-2 and the 24p3 Receptor in the Offspring of Obese Rats","authors":"Edgar Castrejón, L. Manuel-Apolinar, L. Damasio, Rebeca López-ballesteros, M. C. Revilla-Monsalve, E. D. L. Chesnaye","doi":"10.9734/bpi/nfmmr/v5/11473d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/11473d","url":null,"abstract":"Currently, metabolic syndrome constitutes both a medical and an economic problem that affects most countries. Obesity, which is one of its components, affects millions of individuals worldwide. Numerous studies have described an association between high circulating levels of the adipokine lipocalin?2 (Lcn2) and different components of the metabolic syndrome. The latter is of concern because obesity occurs jointly with a state of chronic inflammation, causing dysregulation in adipokine synthesis, often associated with the development of other cardiometabolic alterations. Also, it is known that an obesogenic environment during pregnancy alters the fetal expression of different molecules, including adipokines. We recently demonstrated that mRNA and protein expression of Lcn2 and its receptor (24p3R) is dysregulated in gonads collected from the offspring of obese rats at different times of development. From the results obtained, we concluded that maternal obesity changes the expression of Lcn2 and 24p3R in the gonads of the offspring of obese rats, possibly through fetal programming. The consequences of this dysregulation for the offspring's gonadal function remain to be determined.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115598477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current knowledge of Epigenetic Events in Multiple Myeloma","authors":"P. Flodrová, Petra Luzna, Denisa Weiser-Drozdkova, K. Trtkova","doi":"10.9734/bpi/nfmmr/v5/11646d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/11646d","url":null,"abstract":"Multiple myeloma (MM) is a biologically heterogenic disease with adequate wide spectrum of chromosomal, genetic and epigenetic changes. Epigenetic modifications can influence gene activity without changing the DNA sequence. There are biochemical modifications that include DNA methylation and post-translational modification of histone proteins (histone methylation, histone acetylation and deacetylation), that play an important role in the pathogenesis of MM. Epigenetic modifications are mediated through very important specialized enzymatic molecules, e.g. DNA methyltransferases (DNMTs), ten-eleven translocation enzymes (TET), histone acetyltransferases (HATs) and histone deacetylases (HDACs). In a complex machinery, specific of micro-RNA molecules contribute to epigenetic processes. Not only in myeloma genesis, but epigenetics influences a drug resistance and prognosis of patients with MM as well.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131381616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on COVID-19 and Diabetes Mellitus: Unravelling the Hypotheses that Worsen the Prognosis","authors":"R. Albulescu, S. Dima, I. Florea, D. Lixandru, A. Serban, Veronica Mãdãlina Aspriţoiu, C. Tanase, I. Popescu, S. Ferber","doi":"10.9734/bpi/nfmmr/v5/9973d","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/9973d","url":null,"abstract":"Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and the caused disease - coronavirus. COVID-19 represents an unattended threat for health and life. In the present review we are addressing several hypotheses that may explain why diabetic patients with SARS-CoV-2 infection are at higher risk of experiencing a severe form COVID-19 disease.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131650784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reverence Thru Cadaveric Oath: The Need of the Hour","authors":"M. Gaikwad","doi":"10.9734/bpi/nfmmr/v5/3499f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/3499f","url":null,"abstract":"In today’s scenario the doctor –patient relationship is getting from bad to worse because of the lack of communication skills in undergraduate students pursuing medicine. Acquiring knowledge through dissection of human body is an age-old concept started in 15th century by barber surgeons to demonstrate the structure of human body. Students pursuing medical profession have Anatomy as one of the three basic pre-clinical subjects in there very first year of medical career. Importance of cadaveric dissection for learning anatomy helps the students in developing spatial and tactile appreciation of the structures which cannot be obtained by prosected specimens, computerized learning aids or any other virtual dissection tables. Cadaver being their first teacher, students should be imbibed with the moral values and have gratitude towards the cadaver for helping them understand the structures of the body through dissection. Cadaveric oath recitation will help the students in developing empathy with the cadaver as a “SILENT TEACHER” and in the long run with the patients while serving the humanity by way of medical practice.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122121554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of High Sensitivity C-Reactive Protein in Metabolic Syndrome","authors":"P. K. Gowdaiah, T. Mamatha, Dyaneshwar Nirgude, P. Hosamani","doi":"10.9734/bpi/nfmmr/v5/3434f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/3434f","url":null,"abstract":"Background: A persons personal risk of having cardiovascular disease and type 2 diabetes mellitus is significantly increased if they have metabolic syndrome. Obesity and type 2 diabetes have both become epidemic in India. Metabolic syndrome is a pro-inflammatory condition characterised by low-grade systemic inflammation. The biomarker C-reactive protein (CRP) is a reliable indicator of persistent systemic inflammation. Higher levels of high sensitivity C-reactive protein (Hs-crp) are linked to metabolic syndrome and its components, and can help predict the development of cardiovascular events in the future. \u0000Study objectives: 1) Association of High sensitivity C reactive protein with metabolic syndrome 2)Study of High sensitivity C reactive protein as a surrogate marker of chronic inflammation in the metabolic syndrome \u0000Materials and Methods: This cross sectional study included 50 patients with metabolic syndrome aged 18 and up, as well as 50 age and sex matched controls who visited the OPD or were admitted to the Bangalore Medical College medical department wards. The metabolic syndrome was diagnosed using the updated IDF criteria.For the measurement of hs-CRP, blood glucose, and lipid profile, a fasting blood sample was taken.At the same time, the waist circumference, height, and weight were measured.The information was tabulated and analysed. \u0000Results: There was a statistically significant difference in values of various demographic parameters such as BMI, waist circumference, blood pressure, and biochemical parameters such as blood sugar and lipid profile between cases and controls. Patients with metabolic syndrome had higher mean value of hs-CRP (8.3±1.04 Vs 1.6±0.79mg/l) with a p value <0.001. \u0000Conclusion: When compared to controls, patients with metabolic syndrome had considerably higher levels of hs-CRP, and hs-CRP levels rose linearly with the number of metabolic syndrome components. As a result, in patients with metabolic syndrome, hs-CRP can most likely be utilised as a proxy marker of chronic inflammation.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"2013 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128784285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of Serological Profile of Rheumatoid Arthritis in a Tertiary Care Hospital","authors":"P. K. Surendran","doi":"10.9734/bpi/nfmmr/v5/3557f","DOIUrl":"https://doi.org/10.9734/bpi/nfmmr/v5/3557f","url":null,"abstract":"Rheumatoid Arthritis (RA) is an autoimmune based inflammatory pathology with involvement of joints that show early morning stiffness alongwith pain resulting in loss of function. It usually affects females aged 30 years or above. A total of 150 patients of Rheumatoid Arthritis were included in the present study of which 120 were females and 30 males (F:M=4:1). Serological tests were carried out in these patients. These test were analyzed for their sensitivity as well as specificity. Combination of various test were also assessed for their results. The objective ofpresent study is to analyse, age and sex of patient affected by Rheumatoid arthritis; and to determine whether combination of serological tests enhance specificity. as can be seen fmQuantitative Rheumatoidfactor estimation and Anti Rheumatoid antibodies assay gave the maximum specificity of 89.8%. A combination of serological tests is advisable rather than a single diagnostic test. This allows for the early diagnosis of Rheumatoid Arthritis so as to prevent complications by the disease.","PeriodicalId":306964,"journal":{"name":"New Frontiers in Medicine and Medical Research Vol. 5","volume":"46 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128051210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}