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Serbian Journal of Dermatology and Venereology最新文献

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Apocrine Adenocarcinoma with Extramammary Pagetoid Spread into the Groin: a Case Report and a Literature Review 大汗腺癌伴乳外样斑扩散至腹股沟:1例报告并文献复习
Serbian Journal of Dermatology and Venereology Pub Date : 2016-12-01 DOI: 10.1515/sjdv-2016-0017
B. Lekić, M. Gajić‐Veljic, D. Škiljević, S. Popadic, L. Medenica
{"title":"Apocrine Adenocarcinoma with Extramammary Pagetoid Spread into the Groin: a Case Report and a Literature Review","authors":"B. Lekić, M. Gajić‐Veljic, D. Škiljević, S. Popadic, L. Medenica","doi":"10.1515/sjdv-2016-0017","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0017","url":null,"abstract":"Abstract Apocrine adenocarcinoma is a rare form of sweat gland malignancy mostly affecting adults without evident prevalence for sex or race. Clinically, it presents as a single or a multi-nodular mass or plaque in the axillary or anogenital region, with no additional symptoms. This neoplasm is locally invasive, grows slowly and has an ability to metastasize to visceral organs, regional lymph nodes and bones. We report a case of infiltrating apocrine adenocarcinoma on the scrotum and pubic area with extramammary pagetoid spread into the groin. The immunohistological staining patterns suggested that both extramammary Paget’s disease and apocrine adenocarcinoma derived from the apocrine gland, because the tumor cells were positive for cytokeratin (CK) 7 and gross cystic disease fluid protein-15 (GCDFP-15), but negative for CK20 and prostate-specific antigen (PSA). The results of this case study will facilitate the understanding of this malignant tumor.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"201 - 206"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67058477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Folliculotropic Mycosis Fungoides - A Case Report 嗜滤泡性蕈样真菌病1例报告
Serbian Journal of Dermatology and Venereology Pub Date : 2016-12-01 DOI: 10.1515/sjdv-2016-0019
Ivana Ilijin, Z. Mijuskovic, D. Brasanac, L. Kandolf Sekulovič
{"title":"Folliculotropic Mycosis Fungoides - A Case Report","authors":"Ivana Ilijin, Z. Mijuskovic, D. Brasanac, L. Kandolf Sekulovič","doi":"10.1515/sjdv-2016-0019","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0019","url":null,"abstract":"Abstract Mycosis fungoides (MF) belongs to a group of primary cutaneous T-cell lymphomas, with characteristic small- to medium-sized neoplastic T-lymphocytes with hyperchromatic and cerebriform nuclei. Folliculotropic mycosis fungoides (FMF) represents a variant of mycosis fungoides, which is histologically characterized by folliculotropic T-cell infiltrates, with or without mucinous degeneration of the hair follicles. Clinical features of FMF are characterized by appearance of grouped follicular papules, acneiform lesions, indurated plaques, sometimes tumors, which usually involve the head and neck region. The diagnosis is based on clinical presentation, histopathological and immunohistochemical (IHC) findings of skin biopsy specimens. The treatment of FMF, and generally MF, should be stage-adapted. Case report: We present a case of a 33-year-old male with an eight-month history of erythematous papules on his forehead accompanied by intense pruritus. Histopathological findings showed folliculotropic and perivascular lymphocytic infiltrates. An increased CD4/CD8 ratio of interfollicular lymphocytes with accumulation of Langerhans cell confirmed the diagnosis of FMF. Our patient was diagnosed with an early stage - IA, and P-UVA phototherapy was recommended due to ineffectiveness of prescribed topical corticosteroids that had shortterm effects. Conclusion: Folliculotropic mycosis fungoides represents a diagnostic challenge due to the great diversity of clinical manifestations. We presented a rare case of folliculotropic mycosis fungoides in a young adult, who presented with erythematous papules, accompanied by intense pruritus on the forehead, which lasted for several months. Histopathological and IHC analysis confirmed the diagnosis of folliculotropic mycosis fungoides stage IA. Due to an inadequate response to a topical corticosteroid, P-UVA phototherapy was administered, as well as close follow-up, essential for timely treatment of this frequently therapy-resistant disease.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"213 - 220"},"PeriodicalIF":0.0,"publicationDate":"2016-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67058526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
National Guidelines for the Treatment of Atopic Dermatitis 国家特应性皮炎治疗指南
Serbian Journal of Dermatology and Venereology Pub Date : 2016-09-01 DOI: 10.1515/sjdv-2016-0012
S. Popadic, M. Gajić‐Veljic, S. Prcic, Z. Mijuskovic, D. Jovanović, L. Kandolf-Sekulovic, M. Nikolic
{"title":"National Guidelines for the Treatment of Atopic Dermatitis","authors":"S. Popadic, M. Gajić‐Veljic, S. Prcic, Z. Mijuskovic, D. Jovanović, L. Kandolf-Sekulovic, M. Nikolic","doi":"10.1515/sjdv-2016-0012","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0012","url":null,"abstract":"1Clinic of Dermatovenereology, Clinical Center of Serbia, Department of Dermatovenereology, School of Medicine, University of Belgrade, Belgrade, Serbia 2Institute for Child and Youth Health Care of Vojvodina, Faculty of Medicine, University of Novi Sad, Serbia 3Clinic of Skin and Venereal Diseases, Military Medical Academy, Department of Dermatovenereology, School of Medicine, University of Belgrade, Belgrade, Serbia 4Department of Dermatovenereology, Clinic of Skin and Venereal Diseases, Clinical Center Niš, School of Medicine, University of Niš, Niš, Serbia","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"129 - 153"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/sjdv-2016-0012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Dermoscopy of difficult-to-diagnose Melanomas 难以诊断的黑色素瘤的皮肤镜检查
Serbian Journal of Dermatology and Venereology Pub Date : 2016-09-01 DOI: 10.1515/sjdv-2016-0011
Chrysoula Papageorgiou, D. Ioannides, Z. Apalla, E. Vakirlis, E. Lazaridou, E. Sotiriou, A. Lallas
{"title":"Dermoscopy of difficult-to-diagnose Melanomas","authors":"Chrysoula Papageorgiou, D. Ioannides, Z. Apalla, E. Vakirlis, E. Lazaridou, E. Sotiriou, A. Lallas","doi":"10.1515/sjdv-2016-0011","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0011","url":null,"abstract":"Abstract Dermoscopy is a non-invasive procedure that allows the evaluation of cutaneous lesions, and is considered to be a useful tool that improves the diagnostic accuracy of melanoma. Many dermoscopic criteria of melanoma have been established and several algorithms have been created for melanoma detection. However, the recognition of some melanomas remains challenging. Melanomas on specific body sites, melanomas in patients with multiple atypical moles, and nodular melanomas represent the most difficult-to-recognize melanoma subtypes, since they typically lack the “classic” melanoma-specific criteria. This paper provides an update on dermoscopy of difficult-to-diagnose melanomas by summarizing the newest data. Lastly, we highlight the importance of digital dermoscopy in the follow-up of melanocytic lesions for the detection of incipient melanomas while maintaining a low excision rate.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"121 - 127"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/sjdv-2016-0011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67058105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutaneous Sarcoidosis in a patient with left Hilar calcification of the lungs - A Case Report 皮肤结节病伴左肺门钙化1例报告
Serbian Journal of Dermatology and Venereology Pub Date : 2016-09-01 DOI: 10.1515/sjdv-2016-0014
M. Paravina, M. Ljubenovic, M. Stanojevic, M. Stepanović, D. Marković
{"title":"Cutaneous Sarcoidosis in a patient with left Hilar calcification of the lungs - A Case Report","authors":"M. Paravina, M. Ljubenovic, M. Stanojevic, M. Stepanović, D. Marković","doi":"10.1515/sjdv-2016-0014","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0014","url":null,"abstract":"Abstract Sarcoidosis is an acquired idiopathic granulomatous disease, which is characterized by noncaseating epithelioid granulomas in organs and tissues. Most frequently it affects the lungs, liver, lymph nodes, skin, eyes and other organs. The cutaneous lesions appear in 20 - 30% of patients with systemic manifestations, and in 25% of them they appear without systemic manifestations. Based on the histopathological characteristics, cutaneous lesions are divided into specific, characterized by cutaneous granuloma, and non-specific, which are not granulomatous. Moreover, they can be classified as typical and atypical. We are presenting a female patient with unilateral hilar calcification of the lungs, who exhibited plaque skin lesions typical for sarcoidosis, with a specific granulomatous histology and a favorable response to corticosteroid and antimalarial therapy.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"161 - 170"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Verrucous Carcinoma of the Foot - Report of Two Cases 足部疣状癌2例报告
Serbian Journal of Dermatology and Venereology Pub Date : 2016-09-01 DOI: 10.1515/sjdv-2016-0013
J. Lalošević, B. Lekić, M. Gajić‐Veljic, D. Škiljević, K. Đukić, L. Medenica
{"title":"Verrucous Carcinoma of the Foot - Report of Two Cases","authors":"J. Lalošević, B. Lekić, M. Gajić‐Veljic, D. Škiljević, K. Đukić, L. Medenica","doi":"10.1515/sjdv-2016-0013","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0013","url":null,"abstract":"Abstract Verrucous carcinoma (VC) is a rare variant of a well-differentiated squamous cell carcinoma (SCC) with a low grade of malignancy. Epithelioma cuniculatum (EC) is a subtype of VC, usually found on the sole of the foot. Two patients, a 55-year-old female, and a 77-year-old male, with VC were treated at the Clinic of Dermatology and Venereology, Clinical Center of Serbia, from 2002 to 2011. Both patients presented with a tumor on the foot. Incisional biopsies showed a well differentiated squamous cell carcinoma. Foot x-rays showed bone involvement in one case. One patient underwent surgical amputation of the lower extremity, while the other had a partial amputation of the affected foot. In the initial stage of the disease, it is difficult to distinguish pseudoepitheliomatous hyperplasia from verrucous carcinoma. The superficial biopsy of EC lesion may mislead to a histopathological diagnosis of warts or condylomas. Multiple deep biopsies are necessary for accurate and timely diagnosis of verrucous carcinoma.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"155 - 160"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/sjdv-2016-0013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Comorbidity: Dermatitis Herpetiformis and Sarcoidosis - A Case Report 一罕见的合并症:疱疹样皮炎及结节病1例报告
Serbian Journal of Dermatology and Venereology Pub Date : 2016-09-01 DOI: 10.1515/sjdv-2016-0015
Stoyan Ivanov Pavlov, Irina Ivanova Ivanova, Hristo Boychev Popov, Maria Angelova Tzaneva, Peter Ivanov Ghenev
{"title":"A Rare Comorbidity: Dermatitis Herpetiformis and Sarcoidosis - A Case Report","authors":"Stoyan Ivanov Pavlov, Irina Ivanova Ivanova, Hristo Boychev Popov, Maria Angelova Tzaneva, Peter Ivanov Ghenev","doi":"10.1515/sjdv-2016-0015","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0015","url":null,"abstract":"Abstract Sarcoidosis is an enigmatic, multisystem granulomatous disease of unknown etiology and wide range of clinical presentations. Case report: A 54-year-old female presented with facial rash: polymorphic, round, infiltrated erythematous plaques, 1 - 3 cm in size, disseminated on several areas of the face. The medical history was consistent with dermatitis herpetiformis and persistent intrahepatic cholestasis. The laboratory test results suggested celiac disease (strong positivity of IgA anti-tissue transglutaminase antibodies) but upper endoscopy was not performed to confirm it. The skin biopsy revealed noncaseating epithelioid-cell granulomas, and negative direct immunofluorescence showed IgA deposits in the dermis. Sarcoidosis with cutaneous and hepatic involvement was established based on compatible clinical findings and supportive histology. The period between manifestations of Duhring disease and skin manifestations of sarcoidosis was 20 years. Conclusion: Our clinical case supports the hypothesis for common immune pathogenic factors in gluten-sensitive diseases and sarcoidosis. The simultaneous occurrence of celiac disease and sarcoidosis is rare, but should not be under recognized.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"171 - 176"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/sjdv-2016-0015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serological Tests for Acquired Syphilis in Immuno-competent Patients 免疫正常患者获得性梅毒的血清学检测
Serbian Journal of Dermatology and Venereology Pub Date : 2016-06-01 DOI: 10.1515/sjdv-2016-0007
Z. Golušin, M. Jovanović, M. Matic, L. Vujanović, T. Roš, Biljana Jeremić
{"title":"Serological Tests for Acquired Syphilis in Immuno-competent Patients","authors":"Z. Golušin, M. Jovanović, M. Matic, L. Vujanović, T. Roš, Biljana Jeremić","doi":"10.1515/sjdv-2016-0007","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0007","url":null,"abstract":"Abstract Serological tests represent a valuable tool for the diagnosis and monitoring the syphilis treatment. Non-treponemal antibodies are nonspecific to detect the infection, but antibody titers are used to monitor the effects of syphilis treatment. A definitive diagnosis of syphilis is made using treponemal tests, because they detect specific antibodies to the treponemal strains or treponemal fragments, which cause syphilis. These tests may remain reactive for years, sometimes for life, regardless of the therapy outcome. Even after successful treatment, approximately 85% of patients remain positive for treponemal antibodies for the rest of their lives. However, treponemal tests cannot differentiate past infections from a current infection. Therefore, we use a combination of specific and non-specific tests, the two most frequently used diagnostic algorithms. The traditional algorithm begins with a non-treponemal assay, and if it is positive, the treponemal test is done. A positive treponemal test indicates syphilis. The reverse serology algorithm detects early, primary, and treated syphilis that may be missed with traditional screening. However, non-treponemal test is necessary to detect patients with active syphilis.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"79 - 87"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/sjdv-2016-0007","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Granuloma Annulare-like Wells Syndrome in a Child - A Case Report 儿童肉芽肿环状样威尔斯综合征1例报告
Serbian Journal of Dermatology and Venereology Pub Date : 2016-06-01 DOI: 10.1515/sjdv-2016-0008
B. Lekić, M. Gajić‐Veljic, M. Nikolic
{"title":"Granuloma Annulare-like Wells Syndrome in a Child - A Case Report","authors":"B. Lekić, M. Gajić‐Veljic, M. Nikolic","doi":"10.1515/sjdv-2016-0008","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0008","url":null,"abstract":"Abstract Wells syndrome (WS) is a rare inflammatory skin disease of unknown etiology. Possible triggers for WS include insect bites/stings, infections, medications, malignancies, and vaccination. Most cases have been reported in adults, but WS may also occur in children. We report a case of idiopathic WS in a 12-year-old boy, who presented with pruritic papulonodular and granuloma annulare-like lesions on his legs. The patient had an excellent response to topical and systemic corticosteroids. WS may present as plaque, granuloma annulare-like, urticaria-like, papulovesicular, bullous, papulonodular, or fixed drug eruption-like lesions. Erythematous annular lesions are most common in adults, while plaques are mostly found in children. The histopathologic features are dynamic, starting with dermal edema and infiltration of eosinophils, then flame figures develop, and finishing with the appearance of histiocytes and giant cells. Our patient represents a rare pediatric case with granuloma annulare-like WS syndrome.","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"88 - 94"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Serbian Association of Dermatovenereologists’ Guidelines for the Diagnosis and Treatment of Psoriasis 塞尔维亚皮肤性病医师协会银屑病诊断和治疗指南
Serbian Journal of Dermatology and Venereology Pub Date : 2016-06-01 DOI: 10.1515/sjdv-2016-0006
Z. Mijuskovic, L. Kandolf-Sekulovic, D. Tiodorovic, M. Nikolic, M. Jovanović, D. Škiljević, Z. Gajinov, R. Zečević
{"title":"Serbian Association of Dermatovenereologists’ Guidelines for the Diagnosis and Treatment of Psoriasis","authors":"Z. Mijuskovic, L. Kandolf-Sekulovic, D. Tiodorovic, M. Nikolic, M. Jovanović, D. Škiljević, Z. Gajinov, R. Zečević","doi":"10.1515/sjdv-2016-0006","DOIUrl":"https://doi.org/10.1515/sjdv-2016-0006","url":null,"abstract":"1Clinic of Dermatovenereology, School of Medicine, Military Medical Academy, Belgrade, Republic of Serbia 2Clinic of Dermatovenereology, Clinical Center of Niš, Faculty of Medicine, University of Niš, Republic of Serbia 3Clinic of Dermatovenereology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Republic of Serbia 4Clinic of Dermatovenereology, Clinical Center of Vojvodina, Faculty of Medicine, University of Novi Sad, Republic of Serbia","PeriodicalId":30659,"journal":{"name":"Serbian Journal of Dermatology and Venereology","volume":"8 1","pages":"61 - 78"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1515/sjdv-2016-0006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67057790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
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