足部疣状癌2例报告

Serbian Journal of Dermatology and Venereology Pub Date : 2016-09-01 DOI:10.1515/sjdv-2016-0013

J. Lalošević, B. Lekić, M. Gajić‐Veljic, D. Škiljević, K. Đukić, L. Medenica

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引用次数: 0

摘要

摘要:疣状癌(VC)是一种少见的低恶性分级的高分化鳞状细胞癌(SCC)。弓形上皮瘤(EC)是VC的一种亚型，常见于足底。2002年至2011年，塞尔维亚临床中心皮肤病和性病学诊所治疗了两名患有VC的患者，一名55岁女性和一名77岁男性。两名患者的脚部都有肿瘤。切口活检显示为高分化鳞状细胞癌。足部x光片显示一例骨受累。一名患者接受了下肢截肢手术，而另一名患者则对患足进行了部分截肢。在疾病的初期，很难区分假上皮瘤性增生和疣状癌。EC病变的浅表活检可能会误导疣或尖锐湿疣的组织病理学诊断。为了准确及时地诊断疣状癌，多次深部活检是必要的。

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Verrucous Carcinoma of the Foot - Report of Two Cases

Abstract Verrucous carcinoma (VC) is a rare variant of a well-differentiated squamous cell carcinoma (SCC) with a low grade of malignancy. Epithelioma cuniculatum (EC) is a subtype of VC, usually found on the sole of the foot. Two patients, a 55-year-old female, and a 77-year-old male, with VC were treated at the Clinic of Dermatology and Venereology, Clinical Center of Serbia, from 2002 to 2011. Both patients presented with a tumor on the foot. Incisional biopsies showed a well differentiated squamous cell carcinoma. Foot x-rays showed bone involvement in one case. One patient underwent surgical amputation of the lower extremity, while the other had a partial amputation of the affected foot. In the initial stage of the disease, it is difficult to distinguish pseudoepitheliomatous hyperplasia from verrucous carcinoma. The superficial biopsy of EC lesion may mislead to a histopathological diagnosis of warts or condylomas. Multiple deep biopsies are necessary for accurate and timely diagnosis of verrucous carcinoma.

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Serbian Journal of Dermatology and Venereology

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期刊介绍： Serbian Journal of Dermatology and Venereology is a journal of the Serbian Association of Dermatologists and Venereologists. The journal is published in English, quarterly and intended to provide rapid publication of papers in the field of dermatology and venereology. Manuscripts are welcome from all countries in the following categories: editorials, original studies, review articles, professional articles, case reports, and history of medicine.