Surgery Research and Practice最新文献_第9页

Incidence and Etiology of Surgical Site Infections among Emergency Postoperative Patients in Mbarara Regional Referral Hospital, South Western Uganda 乌干达西南部姆巴拉拉地区转诊医院急诊术后患者手术部位感染的发生率和病因学

Surgery Research and Practice Pub Date : 2017-01-12 DOI: 10.1155/2017/6365172

Abubaker Lubega, Bazira Joel, Najjuka Justina Lucy

{"title":"Incidence and Etiology of Surgical Site Infections among Emergency Postoperative Patients in Mbarara Regional Referral Hospital, South Western Uganda","authors":"Abubaker Lubega, Bazira Joel, Najjuka Justina Lucy","doi":"10.1155/2017/6365172","DOIUrl":"https://doi.org/10.1155/2017/6365172","url":null,"abstract":"Background. This prospective hospital based study was conducted to determine the incidence, risk factors, and causative agents of surgical site infection their susceptibility to among 114 emergency postoperative patients at the Mbarara Regional Referral Hospital between September 2014 and January 2015. Methods. Consented patients were consecutively enrolled and their preoperative, intraoperative, and postoperative data were collected. Follow-ups were done in the surgical outpatient clinics. Wound specimens were collected and processed as per Sops; susceptibility testing was done using the Kirby-Bauer disc diffusion technique. Data was analyzed using STATA 11.0. Results. Overall SSI incidence was 16.4%: 5.9% superficial and 47.1% deep and organ space SSIs each. Klebsiella pneumoniae was the most predominant organism (50%) followed by Staphylococcus aureus (27.8%). E. coli and P. aeruginosa both accounted for 11.1%. Wound class (p = 0.009), anaemia (p = 0.024), low serum albumin (p = 0.046), and property of suture material used (p = 0.006) were significantly associated with SSIs. All organisms had 100% resistance to ampicillin, tetracycline, septrin, and erythromycin. Ciprofloxacin and ceftriaxone are highly sensitive to all organisms. Conclusion. The incidence of SSI in this hospital is very high. Klebsiella pneumoniae is the predominant cause. Ciprofloxacin are very potent antibiotics against organisms that cause SSI.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2017-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89704635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 58

Prediction of Severity of Acute Pancreatitis Using Total Serum Calcium and Albumin-Corrected Calcium: A Prospective Study in Tertiary Center Hospital in Nepal. 用血清总钙和白蛋白校正钙预测急性胰腺炎严重程度:尼泊尔三级中心医院的前瞻性研究

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-12-19 DOI: 10.1155/2017/1869091

Ashik Pokharel, Prem Raj Sigdel, Suman Phuyal, Prasan Bir Singh Kansakar, Pradeep Vaidya

{"title":"Prediction of Severity of Acute Pancreatitis Using Total Serum Calcium and Albumin-Corrected Calcium: A Prospective Study in Tertiary Center Hospital in Nepal.","authors":"Ashik Pokharel, Prem Raj Sigdel, Suman Phuyal, Prasan Bir Singh Kansakar, Pradeep Vaidya","doi":"10.1155/2017/1869091","DOIUrl":"https://doi.org/10.1155/2017/1869091","url":null,"abstract":"Introduction: Total calcium (TC) and albumin-corrected calcium (ACC) are easily accessible AP severity tests in the Primary Health Care Center of Nepal. The aim of the study was to evaluate TC and ACC as prognostic severity markers in acute pancreatitis (AP).Methods: All patients admitted in Tribhuvan University Teaching Hospital with the diagnosis of AP were studied prospectively over a period of one year from January 2015 to January 2016. TC and ACC were measured in the first 24 hours of admission in each patient. The modified Marshall score was determined at admission and at 48 hours and at any point of time during admission as per the need of the patient. Severity of acute pancreatitis was defined as per the Revised Atlanta Classification 2012.Results: 80 patients of AP were included in the study. Among them, 14% were categorized as having severe AP. The mean total calcium was 8.22, 7.51, and 6.98 for mild, moderate, and severe AP, respectively, which was significant at 0.001.Conclusion: TC and ACC, measured within the first 24 hours, are useful severity predictors in acute pancreatitis.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"1869091"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/1869091","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35803124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

A Single Centre Experience of Day Case Laparoscopic Cholecystectomy Outcomes by Body Mass Index Group. 按体重指数组别对日间病例腹腔镜胆囊切除术结果的单中心经验。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-09-28 DOI: 10.1155/2017/1017584

Kirk Bowling, Samantha Leong, Sarah El-Badawy, Erfan Massri, Jaideep Rait, Jay Atkinson, Gandrapu Srinivas, Stuart Andrews

{"title":"A Single Centre Experience of Day Case Laparoscopic Cholecystectomy Outcomes by Body Mass Index Group.","authors":"Kirk Bowling, Samantha Leong, Sarah El-Badawy, Erfan Massri, Jaideep Rait, Jay Atkinson, Gandrapu Srinivas, Stuart Andrews","doi":"10.1155/2017/1017584","DOIUrl":"10.1155/2017/1017584","url":null,"abstract":"Aim: The purpose of this study was to evaluate whether patients with a high BMI can undergo safe day case LC for cholecystitis compared to groups of patients with a lower BMI.Setting: NHS District General Hospital, UK.Methods: A retrospective review of 2391 patients who underwent an attempted day case LC between 1 January 2009 and 15 August 2015 was performed. Patients were divided into five groups depending on their BMI. Inclusion criteria were patients undergoing elective day case laparoscopic cholecystectomy with cholecystitis on histology. The endpoints were complication requiring readmission and postoperative length of stay (LOS).Results: There were 2391 LCs performed in the time period of which 1646 were eligible for inclusion. These LCs were classified as 273 (16.9%), 608 (37.8%), 428 (26.6%), 208 (12.9%), and 91 (5.66%) patients in the groups with BMI values of 18.5-24.9, 25-29.9, 30-34.9, 35-39.9, and >40, respectively. Average BMI was 30.0 (±5.53, 19-51) with an average postoperative LOS of 0.86, and there was no difference between the BMI groups. Overall complication rate was 4.3%; there was no significance between BMI groups.Conclusions: Increased BMI was not associated with worse outcomes after day case LC.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"1017584"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5637831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35514635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Viability of Airborne Tumor Cells during Excision by Ultrasonic Device. 超声装置切除过程中空气传播肿瘤细胞的生存能力。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-04-09 DOI: 10.1155/2017/4907576

Masakazu Hashimoto, Tsuyoshi Kobayashi, Hirotaka Tashiro, Shintaro Kuroda, Yoshihiro Mikuriya, Tomoyuki Abe, Yuka Tanaka, Hideki Ohdan

{"title":"Viability of Airborne Tumor Cells during Excision by Ultrasonic Device.","authors":"Masakazu Hashimoto, Tsuyoshi Kobayashi, Hirotaka Tashiro, Shintaro Kuroda, Yoshihiro Mikuriya, Tomoyuki Abe, Yuka Tanaka, Hideki Ohdan","doi":"10.1155/2017/4907576","DOIUrl":"https://doi.org/10.1155/2017/4907576","url":null,"abstract":"Background. Laparoscopic surgery has become more widely used, but peritoneal dissemination and port-site metastasis have been reported to occur in these surgeries. One reason for these problems is the ultrasonically activated scalpel (UAS) used for laparoscopic surgery. This study aimed to investigate the viability of airborne cells released during cancer dissection using a UAS. Methods. Flank tumors measuring about 2 cm were induced in male NOD-Cg-Rag1tm1MomIL2rgtm1wjl/SzJ mice by subcutaneous injection of 1 × 106 HepG2 cells. Dissection was performed with UAS (in high or low power modes) and PowerStar bipolar scissors. The mist of released tissue was collected in cell culture medium. The viability of the cellular material was assessed with trypan blue exclusion cell counting, counting after immunofluorescence staining, and flow cytometric analysis. Results. Large quantities of cellular debris were trapped in the tissue dispersed by both devices. In all experiments, there were significantly more viable cells produced by the UAS in high power mode. By using suction at the excision site, the number of viable cancer cells was reduced. Conclusions. This study demonstrates that viable cancer cells can be released into the nearby environment during tumor ablation with a UAS.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"4907576"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/4907576","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34984824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Clinical Study on the Etiology of Postthyroidectomy Skin Sinus Formation. 甲状腺切除术后皮肤窦形成病因的临床研究。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-03-12 DOI: 10.1155/2017/5283792

Shan Jin, Wuyuntu Bao, Oyungerel Borkhuu, Yun-Tian Yang

{"title":"Clinical Study on the Etiology of Postthyroidectomy Skin Sinus Formation.","authors":"Shan Jin, Wuyuntu Bao, Oyungerel Borkhuu, Yun-Tian Yang","doi":"10.1155/2017/5283792","DOIUrl":"https://doi.org/10.1155/2017/5283792","url":null,"abstract":"Background. Thyroidectomy is one of the most frequently performed surgical procedures worldwide. Despite technical advances and high experience of thyroidectomy of specialized centers, it is still burdened by a significant rate of postoperative complications. Among them, the skin sinus formation is an extremely rare postthyroidectomy complication. Here, we first report the incidence of the skin sinus formation after thyroidectomy to identify the causes for skin sinus formation after thyroidectomy and to discuss its prevention and treatment options. Methods. A retrospective analysis was carried out of patients who underwent excision operation of fistula for postthyroidectomy skin sinus formation. Data were retrieved from medical records department of the Affiliated Hospital of Inner Mongolia Medical University. Results. Of the 5,686 patients who underwent thyroid surgery, only 5 patients (0.088%) had developed skin sinus formation. All 5 patients successfully underwent complete excision of fistula. Conclusion. Infection, foreign body, thyroid surgery procedure, combined disease, and iatrogenic factors may be related with skin sinus formation after thyroidectomy. To reduce the recurrence of postoperative infections and sinus formation, intra- and postoperative compliance with aseptic processing, intraoperative use absorbable surgical suture/ligature, repeated irrigation and drainage, and postoperative administration of anti-inflammatory treatment are to be followed.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"5283792"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/5283792","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34893558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Vacuum-Assisted Abdominal Closure Is Safe and Effective: A Cohort Study in 74 Consecutive Patients. 真空辅助腹部闭合安全有效:74例连续患者的队列研究。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-09-11 DOI: 10.1155/2017/7845963

R O Jensen, T Buchbjerg, R M Simonsen, R Eckardt, N Qvist

{"title":"Vacuum-Assisted Abdominal Closure Is Safe and Effective: A Cohort Study in 74 Consecutive Patients.","authors":"R O Jensen, T Buchbjerg, R M Simonsen, R Eckardt, N Qvist","doi":"10.1155/2017/7845963","DOIUrl":"https://doi.org/10.1155/2017/7845963","url":null,"abstract":"Background: Vacuum-assisted closure (VAC) has, in many instances, become the treatment of choice in patients with abdominal catastrophes. This study describes the use and outcome of ABThera KCI® VAC in the Region Southern Denmark covering a population of approximately 1.202 mill inhabitants.Method: A prospective multicenter study including all patients treated with VAC during an eleven-month period.Results: A total of 74 consecutive patients were included. Median age was 64.4 (9-89) years, 64% were men, and median body mass index was 25 (17-42). Duration of VAC treatment was median 4.5 (0-39) days with median 1 (0-16) dressing changes. Seventy per cent of the patients attended the intensive care unit. The 90-day mortality was 15%. A secondary closure of the fascia was obtained in 84% of the surviving patients. Only one patient developed an enteroatmospheric fistula. Patients with secondary closure were less likely to develop large hernias and had better self-evaluated physical health score (p < 0,05). No difference in mental health was found.Conclusion: The abdominal VAC treatment in patients with abdominal catastrophes is safe and with a relative low complication rate. Whether it might be superior to conventional treatment with primary closure when possible has yet to be proven in a randomized study.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"7845963"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/7845963","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35557642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Intraoperative Injection of Technetium-99m Sulfur Colloid for Sentinel Lymph Node Biopsy in Breast Cancer Patients: A Single Institution Experience. 术中注射锝-99m硫胶体用于乳腺癌前哨淋巴结活检:单一机构经验。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-04-13 DOI: 10.1155/2017/5924802

Julian Berrocal, Lawrence Saperstein, Baiba Grube, Nina R Horowitz, Anees B Chagpar, Brigid K Killelea, Donald R Lannin

{"title":"Intraoperative Injection of Technetium-99m Sulfur Colloid for Sentinel Lymph Node Biopsy in Breast Cancer Patients: A Single Institution Experience.","authors":"Julian Berrocal, Lawrence Saperstein, Baiba Grube, Nina R Horowitz, Anees B Chagpar, Brigid K Killelea, Donald R Lannin","doi":"10.1155/2017/5924802","DOIUrl":"https://doi.org/10.1155/2017/5924802","url":null,"abstract":"Background. Most institutions require a patient undergoing sentinel lymph node biopsy to go through nuclear medicine prior to surgery to be injected with radioisotope. This study describes the long-term results using intraoperative injection of radioisotope. Methods. Since late 2002, all patients undergoing a sentinel lymph node biopsy at the Yale-New Haven Breast Center underwent intraoperative injection of technetium-99m sulfur colloid. Endpoints included number of sentinel and nonsentinel lymph nodes obtained and number of positive sentinel and nonsentinel lymph nodes. Results. At least one sentinel lymph node was obtained in 2,333 out of 2,338 cases of sentinel node biopsy for an identification rate of 99.8%. The median number of sentinel nodes found was 2 and the mean was 2.33 (range: 1-15). There were 512 cases (21.9%) in which a sentinel node was positive for metastatic carcinoma. Of the patients with a positive sentinel lymph node who underwent axillary dissection, there were 242 cases (54.2%) with no additional positive nonsentinel lymph nodes. Advantages of intraoperative injection included increased comfort for the patient and simplification of scheduling. There were no radiation related complications. Conclusion. Intraoperative injection of technetium-99m sulfur colloid is convenient, effective, safe, and comfortable for the patient.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"5924802"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/5924802","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"34984825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 11

Treatment and Outcome for Children with Esophageal Atresia from a Gender Perspective. 从性别角度看儿童食管闭锁的治疗和预后。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-10-22 DOI: 10.1155/2017/8345798

Julia Ekselius, Martin Salö, Einar Arnbjörnsson, Pernilla Stenström

{"title":"Treatment and Outcome for Children with Esophageal Atresia from a Gender Perspective.","authors":"Julia Ekselius, Martin Salö, Einar Arnbjörnsson, Pernilla Stenström","doi":"10.1155/2017/8345798","DOIUrl":"https://doi.org/10.1155/2017/8345798","url":null,"abstract":"Background: Besides the incidence of esophageal atresia (EA) being higher in males, no other gender-specific differences in EA have been reported. The aim of this study was to search for gender-specific differences in EA.Methods: A retrospective study was conducted at a tertiary center for pediatric surgery. The medical charts of infants born with EA were reviewed. 20 girls were identified, and 20 boys were selected as matched controls with respect to concomitant malformations. Their treatment and outcome were evaluated.Results: Polyhydramnios was more common in pregnancies with boys, 40%, versus girls, 10%, with EA (p < 0.01). In total, 36 (90%) children had patent ductus arteriosus, without any gender difference (18 and 18, resp., p=1). The distribution of days at the different levels of care was not equally distributed between boys and girls. Boys with EA had significantly more postoperative days (median 5 days) in the ward than girls (median 5 and 2 days, resp., p=0.04). No other gender-specific differences in surgical treatment, complications, or symptoms at follow-up were identified.Conclusion: Polyhydramnios appears to be more frequent in pregnancies with boys than girls with EA. In this study, boys have longer stays than girls at the pediatric surgery ward.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"8345798"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/8345798","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35216737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Diagnosis and Management of Intraoperative Colorectal Anastomotic Leaks: A Global Retrospective Patient Chart Review Study. 术中结直肠吻合口瘘的诊断和处理:一项全球回顾性患者病历回顾研究。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-06-14 DOI: 10.1155/2017/3852731

A Schiff, S Roy, M Pignot, S K Ghosh, E J Fegelman

{"title":"Diagnosis and Management of Intraoperative Colorectal Anastomotic Leaks: A Global Retrospective Patient Chart Review Study.","authors":"A Schiff, S Roy, M Pignot, S K Ghosh, E J Fegelman","doi":"10.1155/2017/3852731","DOIUrl":"https://doi.org/10.1155/2017/3852731","url":null,"abstract":"Background: This targeted chart review study reports the first ever detailed global account of clinical approaches adopted to detect and manage anastomotic leaks identified during surgery in routine clinical practice.Method: 156 surgeons from eight countries retrospectively extracted data from surgical records of 458 patients who underwent colorectal surgery with an identified intraoperative leak at the circular anastomosis. Demographic details, procedures, and outcomes were analyzed descriptively, by country.Results: Most surgeries were performed laparoscopically (57.6%), followed by open surgeries (35.8%). The burden of intraoperative leaks on the healthcare system is driven in large part by the additional interventions such as using a sealant, recreating the anastomosis, and diverting the anastomosis to a colostomy bag, undertaken to manage the leak. The mean duration of hospitalization was 19.9 days. Postoperative anastomotic leaks occurred in 62 patients (13.5%), most frequently 4 to 7 days after surgery. Overall, country-specific differences were observed in patient characteristics, surgical procedures, method of diagnosis of intraoperative leak, interventions, and length of hospital stay.Conclusion: The potential cost of time and material needed to repair intraoperative leaks during surgery is substantial and often hidden to the healthcare system, potentially leading to an underestimation of the impact of this complication.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"3852731"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/3852731","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35158487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12

Improved Biochemical Parameters in Patients Who Undergo Early Resection in Isolated Ileocaecal Crohn's Disease. 早期切除孤立回盲部克罗恩病患者的生化指标改善。

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-07-10 DOI: 10.1155/2017/4396573

Mirzafaraz Saeed, Hari Hullur, Amro Salem, Abbas Ali, Yousif Sahib, Mobeen Ashfaq

{"title":"Improved Biochemical Parameters in Patients Who Undergo Early Resection in Isolated Ileocaecal Crohn's Disease.","authors":"Mirzafaraz Saeed, Hari Hullur, Amro Salem, Abbas Ali, Yousif Sahib, Mobeen Ashfaq","doi":"10.1155/2017/4396573","DOIUrl":"https://doi.org/10.1155/2017/4396573","url":null,"abstract":"Introduction: The aim of this study is to evaluate the outcome of introduction of early surgery in the course of isolated ileocecal Crohn's disease, where there is no absolute indication of surgery.Methods: Observational study involving patients with isolated ileocecal Crohn's disease who underwent early surgical resection (within one year of the presentation of the hospital). A complete blood count, ESR, and CRP were done and compared between the preoperative value, 1st postoperative visit (3-4 weeks), and last follow-up visit. Statistical analysis was done using Analysis of Variance (ANOVA) to compare the different figures.Results: There was a statistically significant increase in the hemoglobin levels between preoperative, postoperative, and long-term follow-up and a significant decrease in leukocyte count between the pre- and postoperative values (F = 19.8, p < 0.001 and F = 8.9, p = 0.002, resp.). Similarly, the ESR and CRP values were decreased significantly at long-term follow-up (F = 8.5, p = 0.019 and F = 8.3, p = 0.013, resp.).Conclusion: Early surgical resection in isolated ileocaecal Crohn's disease achieved significant biochemical improvements. These successful results in this small number of patients indicate that early surgical intervention may provide better outcomes. These initial results encourage larger and comparative studies of long-term results versus long-term use of biological agents.","PeriodicalId":30584,"journal":{"name":"Surgery Research and Practice","volume":"2017 ","pages":"4396573"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2017/4396573","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35290961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2