Treatment and Outcome for Children with Esophageal Atresia from a Gender Perspective.

Surgery Research and Practice Pub Date : 2017-01-01 Epub Date: 2017-10-22 DOI:10.1155/2017/8345798

Julia Ekselius, Martin Salö, Einar Arnbjörnsson, Pernilla Stenström

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引用次数: 6

Abstract

Background: Besides the incidence of esophageal atresia (EA) being higher in males, no other gender-specific differences in EA have been reported. The aim of this study was to search for gender-specific differences in EA.

Methods: A retrospective study was conducted at a tertiary center for pediatric surgery. The medical charts of infants born with EA were reviewed. 20 girls were identified, and 20 boys were selected as matched controls with respect to concomitant malformations. Their treatment and outcome were evaluated.

Results: Polyhydramnios was more common in pregnancies with boys, 40%, versus girls, 10%, with EA (p < 0.01). In total, 36 (90%) children had patent ductus arteriosus, without any gender difference (18 and 18, resp., p=1). The distribution of days at the different levels of care was not equally distributed between boys and girls. Boys with EA had significantly more postoperative days (median 5 days) in the ward than girls (median 5 and 2 days, resp., p=0.04). No other gender-specific differences in surgical treatment, complications, or symptoms at follow-up were identified.

Conclusion: Polyhydramnios appears to be more frequent in pregnancies with boys than girls with EA. In this study, boys have longer stays than girls at the pediatric surgery ward.

Abstract Image

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从性别角度看儿童食管闭锁的治疗和预后。

背景:除了食管闭锁(EA)在男性中的发病率较高外，没有其他性别差异的报道。本研究的目的是寻找ea的性别差异。方法:回顾性研究在一个三级儿科外科中心进行。回顾了出生时患有EA的婴儿的病历。20名女孩被确定，20名男孩被选择作为伴随畸形的匹配对照。对两组患者的治疗和预后进行评价。结果:羊水过多在EA的男孩中发生率为40%，而在EA的女孩中发生率为10% (p < 0.01)。36例(90%)患儿动脉导管未闭，性别差异无统计学意义(分别为18例和18例)。, p = 1)。男孩和女孩接受不同级别护理的天数分布并不均匀。患有EA的男孩在病房的术后天数(中位数为5天)明显多于女孩(中位数为5天和2天)。, p = 0.04)。随访时未发现手术治疗、并发症或症状方面的其他性别差异。结论:羊水过多似乎在男孩怀孕比女孩EA更常见。在这项研究中，男孩比女孩在儿科外科病房停留的时间更长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Surgery Research and Practice

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期刊介绍： Surgery Research and Practice is a peer-reviewed, Open Access journal that provides a forum for surgeons and the surgical research community. The journal publishes original research articles, review articles, and clinical studies focusing on clinical and laboratory research relevant to surgical practice and teaching, with an emphasis on findings directly affecting surgical management.