K. Nirmal, Vikas Saini, Nadeem Ahmad, Narendra Pal Singh
{"title":"Assessment of blood culture and tube agglutination serology test for the diagnosis of typhoid fever amongst malaria-negative patients: a one-year hospital-based study","authors":"K. Nirmal, Vikas Saini, Nadeem Ahmad, Narendra Pal Singh","doi":"10.4081/hls.2023.11345","DOIUrl":"https://doi.org/10.4081/hls.2023.11345","url":null,"abstract":"Salmonella serotypes, including Salmonella Typhi, S. Paratyphi A, S. Paratyphi B, and S. Paratyphi C, are responsible for the systemic, protracted febrile sickness known as typhoid fever. Various antibody-based tests are being used for diagnosing typhoid fever. This study was carried out to assess the performance of the widal test and blood culture for the diagnosis of typhoid fever among malaria-negative patients in a tertiary care hospital in east Delhi, India. The study was conducted from July 2021 to June 2022 in the Department of Microbiology of a tertiary care hospital in Delhi. Patients, including the adult and pediatric population, were evaluated for typhoid fever and participated in an observational, prospective study on febrile patients that was malaria-negative. Venous blood samples were obtained under strict aseptic conditions and further processed for widal serology and blood culture tests for typhoid fever. In our study, the prevalence of blood culture-positive Salmonella species was 0.3% (30/10,000 = 0.3%) Among antimicrobial susceptibility patterns, S. Typhi revealed the highest resistance rates for Ciprofloxacin (43.33%), Azithromycin (36.66%), and third-generation cephalosporins. Out of 30 blood culture-positive Salmonella Typhi of typhoid fever patients, 5 (17%) samples were negative for the Widal test. Among 30 samples, all were blood culture positive, but only 25 samples show Widal titer above the baseline i.e. >1:64. Although blood culture is the gold standard for the diagnosis of typhoid fever, the Widal test does play a role in the diagnosis and management of typhoid fever, especially in suspected cases when blood culture is negative, especially in government tertiary care hospitals.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"70168454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of MLSB Phenotypes of Staphylococcus aureus isolates in a tertiary care hospital of Delhi","authors":"Malika Grover, N. Goyal, Seema Gangar, N. Singh","doi":"10.4081/hls.2023.11229","DOIUrl":"https://doi.org/10.4081/hls.2023.11229","url":null,"abstract":"Against the backdrop of the ever-changing Staphylococcal resistance pattern, clindamycin remains a viable therapeutic alternative Variation of Clindamycin drug resistance patterns with geographic area make inducible clindamycin resistance testing imperative for all staphylococcal isolates to avoid therapeutic failure. This was a prospective study conducted over a period of 1.5 years from January 2021 until June 2022. Prevalence of different MLSB Phenotypes of Staphylococcus aureus isolates was determined by standard disc diffusion method as per CLSI guidelines. Pyogenic samples received in the Microbiology lab that yielded Staphylococcus aureus were further tested for the presence of clindamycin resistance by disc diffusion method. Out of 6586 total pyogenic and respiratory specimens received in the lab, Staphylococcus aureus was yielded in 752 samples. On further testing for the MLSB phenotypes, 16.3% isolates were found to be iMLSB, 19.28% were cMLSB, 43.1% were of MSB type. ICR screening will reduce the unessential subjection of the patient to the antibiotic, and would prevent unnecessary adverse effects in the patients.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49041144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neveen Rashad Mostafa, Abeer Ahmed Mohamed Ali, Rehab Moustafa Ezzat, Mostafa Kamel Bakry, R. Marzo
{"title":"Value of biochemical markers in predicting outcome of COVID-19 infection in University Hospital, Alexandria, Egypt","authors":"Neveen Rashad Mostafa, Abeer Ahmed Mohamed Ali, Rehab Moustafa Ezzat, Mostafa Kamel Bakry, R. Marzo","doi":"10.4081/hls.2023.11323","DOIUrl":"https://doi.org/10.4081/hls.2023.11323","url":null,"abstract":"This paper aims to examine the value of different biochemical markers in predicting the outcome of COVID-19 infection. A total of 140 patients with confirmed COVID-19 infection by polymerase chain reaction (PCR), different biochemical markers were tested, their relation to the outcome of the disease was monitored, and the most reliable tests were determined. The study found a significant correlation between all evaluated biochemical markers and severity of the disease, including C-reactive protein (CRP), D-dimer, alanine aminotransferase (ALT), Aspartate aminotransferase (AST), prothrombin time (PT), activated partial thromboplastin time (aPTT). In addition, ferritin, lactate dehydrogenase (LDH), procalcitonin (PCT) and Pro- Brain natriuretic peptide (proBNP) demonstrated highly sensitivity and specificity as well as significant prognostic performance. These markers were also independently significant in predicting mortality. Early assessment of biochemical markers in patients with COVID-19 can help clinicians in tailoring treatment and providing more intensive care to those with greater mortality risk. In particular, the assessment of ferritin, LDH, procalcitonin and proBNP can independently predict mortality.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48044411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving healthcare value: integrating medical practitioners into hospital design in developing countries","authors":"C. Noujeim","doi":"10.4081/hls.2023.11183","DOIUrl":"https://doi.org/10.4081/hls.2023.11183","url":null,"abstract":"The cost of healthcare is a burden in most developing countries, and this is exponentially increasing in the context of population growth, pandemics, and rapidly evolving medical necessities. A customized healthcare typology should rely on data collection and architectural requirements, before moving to aesthetically compelling designs, so hospitals in low-resource or developing countries will not mimic their Western counterparts. The greatest bearing that improves the patient’s outcome and well-being would engage a productive interaction between the hospital designers and the medical practitioners, this will also allow for evidence-based hospital planning. As the author of this short report, I use the best of my experience as a physician and healthcare planner to translate a successful interaction with multinational designers building hospitals in Rivers State, Nigeria.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47523927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neveen Rashad Mostafa, Abeer Ahmed Mohamed Ali, R. Marzo
{"title":"The effect of vitamin D deficiency on glycemic control in patients with type 2 diabetes mellitus","authors":"Neveen Rashad Mostafa, Abeer Ahmed Mohamed Ali, R. Marzo","doi":"10.4081/hls.2023.11340","DOIUrl":"https://doi.org/10.4081/hls.2023.11340","url":null,"abstract":"Multiple factors are involved in the development of type 2 diabetes mellitus (T2DM), but an imbalance between free radical formation and antioxidant removal is the main cause of diabetic complications. Micronutrients with antioxidant properties may have a role in the development of diabetes mellitus (DM) and its complications. Vitamin D has recently been found to have membrane antioxidant effect and a relationship to the development of T2DM, as it can modify its risk. Whether vitamin D deficiency has an effect on hyperglycemia in diabetic patients or not need further study. Our aim was to examine the effect of vitamin D deficiency on glycemic control in T2DM. We examined the vitamin D levels of 100 patients with T2DM and correlated them with fasting blood sugar and glycated hemoglobin A1c (HbA1c) levels. High levels of fasting blood sugar and HbA1c levels were significantly associated with vitamin D deficiency. Vitamin D deficiency negatively affects glycemic control in patients with T2DM.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43903637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Maggot therapy could provide affordable and efficacious wound care in Lebanon and other low- and middle-income countries","authors":"Salman Shayya, F. Stadler","doi":"10.4081/hls.2023.11161","DOIUrl":"https://doi.org/10.4081/hls.2023.11161","url":null,"abstract":"The poor economic situation, ongoing political instability, and the 2020 Beirut explosion have seriously eroded the capacity of the Lebanese healthcare system. Insecure fuel supplies and the rationing of electricity to a few hours per day make matters worse. New strategies are required to deliver healthcare that is more resilient in the face of ongoing disruption. Maggot therapy for the treatment of chronic and infected wounds could make a meaningful difference in Lebanon. When placed in a wound, medicinal maggots remove dead tissue, control infection and stimulate wound healing. It is an inexpensive, easy to use, and highly efficacious therapy, even under austere conditions. This review provides an introduction to maggot therapy and briefly explains its therapeutic benefits before discussing the role it can play in the Lebanese healthcare system. Finally, the prerequisites and enablers for successful integration of maggot therapy into the Lebanese healthcare system are outlined.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41718034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fear of COVID-19 among critical care nurses of public hospitals in Lahore: empirical evidence during third wave","authors":"Asma Nadeem, Rubina Jabeen, Shehla Nazir, Shahbaz Haider","doi":"10.4081/hls.2023.10642","DOIUrl":"https://doi.org/10.4081/hls.2023.10642","url":null,"abstract":"The world has seen a pandemic which disrupted the life. Till now there are aftershocks of the COVID-19 such as Omicron instilling fear among individuals. Healthcare staff is on alert specifically the nurses has suffered a lot mentally due to this issue by developing fatigue. The study conducted during deadly 3rd COVID-19 wave. The data were collected by developing the questionnaire of the previously validated measures related to the variables under study from nurses working in the intensive care unit, critical care unit and floor wards of COVID-19 at Services Hospital, Lahore. A total of 140 questionnaires were used for data analysis. The study used Statistical Package for Social Sciences for frequency and descriptive statistics. Whereas, the outcomes of fear of COVID-19 were assessed by using the latest Smart Partial Least Squares software which allows to assess the complex research frameworks. The results of the study revealed that the fear of COVID-19 results in poor quality of life among nurses and fatigue. Resilience among nurses can reduce the negative consequences but did not get the statistical support.","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43005715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Dahmarde, Marzieh Abiri, Sharareh Sanei Sistani
{"title":"Analysis of the potential reasons for repeated radiography: a study in a major hospital in south eastern Iran","authors":"H. Dahmarde, Marzieh Abiri, Sharareh Sanei Sistani","doi":"10.4081/hls.2023.10575","DOIUrl":"https://doi.org/10.4081/hls.2023.10575","url":null,"abstract":"Introduction \u0000Rejecting, removing and repeating the process of taking diagnostic X-ray images could lead to professional and moral challenges in the case of radiologic imaging. The aim of this study was to investigate the reason for repetitive imaging and the types of images mostly repeated. \u0000Methods \u0000Radiographic images taken in this center in the first half of 1400 were evaluated. At the end of each week, repetitive images were referred to the researcher to analyze the frequency of repetitive radiographies and the causes. \u0000Results \u0000In this study, a total of 4916 radiographies taken in Ali Ibn-e-Abitibi Hospital during the first 6 months of the year 1400 were evaluated. Among 398 repetitive radiographies, 94 repetitions (23.62%) were due to inappropriate positioning, 92 repetitions (23.12%) were due to patient's movements, 56 repetitions (14.07%) were due to inadequate radiation, 51 repetitions (12.81%) were due to inadequate processing, 46 repetitions (11.56%) were due to inadequate preparation of the patient, and 59 repetitions(14.82 %) were due to other reasons \u0000Conclusion \u0000In this study, the rate of repetitive radiographies taken in Ali Ibn-e-Abi Talib Hospital was estimated as 8.10%, with the most common reason for repetitions being estimated inappropriate positioning. Considering the fact that repetitive radiography mostly depends on operator-related factors, it is recommended to repeat the study after educating staff in order to compare the rate and reason of repetition. ","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41765104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. Inada, C. A. de Castro, C. F. da Silva, W. Lombardi, Vanderlei Salvador Bagnato
{"title":"High-grade cervical intraepithelial neoplasia treatment comparing two photodynamic therapy protocols","authors":"N. Inada, C. A. de Castro, C. F. da Silva, W. Lombardi, Vanderlei Salvador Bagnato","doi":"10.1117/12.2647382","DOIUrl":"https://doi.org/10.1117/12.2647382","url":null,"abstract":"","PeriodicalId":30412,"journal":{"name":"Healthcare in Lowresource Settings","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88917246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}