Case Reports in Transplantation最新文献_第3页

Complex Vascular Reconstruction of an En Bloc Pediatric Kidney Damaged during Organ Procurement. 复杂血管重建的整体儿童肾脏损害在器官获取。

Case Reports in Transplantation Pub Date : 2022-06-16 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3242809

Juliano Riella, Marina M Tabbara, Phillipe Abreu, Javier Gonzalez, Gaetano Ciancio, José Maria Figueiro

引用次数: 0

Ehrlichiosis in a Recent Liver Transplant Recipient Leading to Multiorgan Failure. 近期肝移植受者埃利希体病导致多器官功能衰竭。

Case Reports in Transplantation Pub Date : 2022-06-10 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3062836

Fawwaz Almajali, Catherine Oleary, Taylor Hallcox, Justin Lok, Daniela Hermelin, Alexis Guenette, Mustafa Nazzal

引用次数: 0

Conservative Management of Muscle Invasive Bladder Cancer in Kidney-Pancreas Transplant Patient 肾胰移植患者肌性浸润性膀胱癌的保守治疗

Case Reports in Transplantation Pub Date : 2022-05-29 DOI: 10.1155/2022/5373414

Logan D. Glosser, Brandon S Zakeri, Conner V Lombardi, O. Ekwenna

{"title":"Conservative Management of Muscle Invasive Bladder Cancer in Kidney-Pancreas Transplant Patient","authors":"Logan D. Glosser, Brandon S Zakeri, Conner V Lombardi, O. Ekwenna","doi":"10.1155/2022/5373414","DOIUrl":"https://doi.org/10.1155/2022/5373414","url":null,"abstract":"Introduction. Solid organ transplant increases the risk for muscle-invasive bladder cancer (MIBC). Although a common tumor, urothelial cell carcinoma (UCC) of the bladder in patients with kidney-pancreas transplants is scarcely reported. Case Presentation. A 65-year-old male with history of type 1 diabetes and a 14-year status post deceased donor pancreas-kidney transplant presented with 3 weeks of gross hematuria. CT scan showed multiple bladder masses. Transurethral resection of bladder tumor (TURBT) showed papillary UCC. 5 months later, the patient reported new-onset gross hematuria. TURBT showed MIBC. The patient elected for bladder-preserving TMT. On cystoscopy there was no gross evidence of carcinoma at 3.5 years of follow up. Discussion. Currently, no specific management guidelines target this population with MIBC. The first-line treatment for MIBC is radical cystectomy (RC) with neoadjuvant chemotherapy. For patients that are medically unfit or unwilling to undergo RC, trimodal therapy (TMT) is an alternative. TMT for bladder cancer consists of complete tumor resection with chemotherapy and radiation. This report demonstrates a unique case of a patient with kidney-pancreas transplant diagnosed with MIBC treated with TMT that has no evidence of gross tumorigenesis at 3.5 years after diagnosis. Our findings suggest that trimodal therapy should be considered for treatment of MIBC in patients with kidney-pancreatic transplants to preserve the donated allografts.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74713808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Living Donor Liver Transplantation for Hepatic Venoocclusive Disease/Sinusoidal Obstruction Syndrome Originating from Hematopoietic Stem Cell Transplantation 活体供肝移植治疗造血干细胞移植引起的肝静脉闭塞性疾病/窦阻塞综合征

Case Reports in Transplantation Pub Date : 2022-05-21 DOI: 10.1155/2022/8361769

Kentaro Ichimura, N. Kawamura, R. Goto, Masaaki Watanabe, Yoshikazu Ganchiku, T. Shimamura, A. Taketomi

{"title":"Living Donor Liver Transplantation for Hepatic Venoocclusive Disease/Sinusoidal Obstruction Syndrome Originating from Hematopoietic Stem Cell Transplantation","authors":"Kentaro Ichimura, N. Kawamura, R. Goto, Masaaki Watanabe, Yoshikazu Ganchiku, T. Shimamura, A. Taketomi","doi":"10.1155/2022/8361769","DOIUrl":"https://doi.org/10.1155/2022/8361769","url":null,"abstract":"Background Venoocclusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), is a life-threatening hematopoietic stem cell transplantation (HSCT) complication. Cases of mild and moderate VOD/SOS are self-limiting; however, the mortality for severe VOD/SOS has reached 80%. Recently, defibrotide became available and has been used for VOD/SOS; however, the outcome for patients with severe VOD/SOS is not satisfactory, and liver transplantation is attempted in these severe cases. Method We describe a case of living donor liver transplantation (LDLT) for acute liver failure secondary to VOD/SOS that originates from HSCT. Result Liver regeneration after LDLT was impaired, and several infections were developed before liver regeneration completion. Our patient suffered sepsis and finally died of multiorgan failure. Conclusion Severe VOD/SOS originating from HSCT is associated with a very poor prognosis. The liver transplantation outcome for VOD/SOS has not been satisfied, but it may provide long-term survival if successful. We considered liver transplantation as a therapeutic option, especially in cases where sufficient graft volume is secured, considering impaired liver regeneration under bone marrow suppression after HSCT.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"60 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80231587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spinal Stroke following Kidney Transplant 肾移植后的脊髓中风

Case Reports in Transplantation Pub Date : 2022-05-21 DOI: 10.1155/2022/2058600

J. Subramanian, Farjad Siddiqui, Pranit N. Chotai, Yazan Al-Adwan, A. Rajab, K. Washburn, A. Schenk, Ashley J Limkemann, Michael D Luttrull, Musab Al-Ebrahim, G. Bumgardner, Navdeep Singh

引用次数: 0

Catastrophic Antiphospholipid Syndrome after Orthotopic Liver Transplant 原位肝移植后的灾难性抗磷脂综合征

Case Reports in Transplantation Pub Date : 2022-05-05 DOI: 10.1155/2022/6209300

R. Okeke, J. Lok, R. Wells, M. Wycoff, A. Engelhardt, J. Bettag, C. O'Leary, T. Hallcox, M. Nazzal

{"title":"Catastrophic Antiphospholipid Syndrome after Orthotopic Liver Transplant","authors":"R. Okeke, J. Lok, R. Wells, M. Wycoff, A. Engelhardt, J. Bettag, C. O'Leary, T. Hallcox, M. Nazzal","doi":"10.1155/2022/6209300","DOIUrl":"https://doi.org/10.1155/2022/6209300","url":null,"abstract":"Background Catastrophic antiphospholipid syndrome (CAPS) is an autoimmune thrombogenic disorder of small and large vessels caused by autoantibodies against phospholipids and phospholipid-binding proteins. This severe form of antiphospholipid syndrome (APS) presents clinically with simultaneous life-threatening multiorgan thrombosis and the presence of two or more persistent antiphospholipid antibodies (APL) confirmed on testing 12 weeks apart. Case Presentation. We describe a case report of a 66-year-old woman with detected antinuclear antibodies (ANA) pretransplant diagnosed with CAPS following orthotopic liver transplant. The patient had acute respiratory failure; Doppler ultrasound and CT angiogram confirmed thrombosis in the hepatic artery, subsequent occlusion of the jump graft, and a splenic infarct. Hypercoagulability workup showed elevated levels of anticardiolipin IgG and beta-2-glycoprotein IgG/IgM and positive lupus anticoagulant, treated with steroids and anticoagulation. The patient was discharged after one month and was transitioned from heparin to life-long warfarin. Conclusion Our patient provided a standard presentation of CAPS with abnormal pretransplant levels of antinuclear antibodies (ANA). Although there have been studies investigating the relationship between anticardiolipin antibodies and lupus anticoagulants and APS, the relationship between pretransplant positive ANA or antimitochondrial antibodies (AMA) and CAPS has yet to be explored. Further studies will be needed to determine the significance of these antibodies. We recommend preoperative APL testing for patients with positive ANA and AMA at preliver transplant presentation.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"44 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79190920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relapsing De Novo Membranous Nephropathy 复发性膜性肾病

Case Reports in Transplantation Pub Date : 2022-05-02 DOI: 10.1155/2022/6754520

Ala Ali, Huda Al-Taee, Thaer J. Kadhim

引用次数: 0

Double-Lung Transplantation in a Patient with Pulmonary Type B Niemann-Pick Disease: A Valid Treatment Option 双肺移植治疗B型尼曼-皮克病:一种有效的治疗选择

Case Reports in Transplantation Pub Date : 2022-04-27 DOI: 10.1155/2022/5428381

V. Mora, J. Osorio, D. Iturbe, S. Tello, Yedra Gómez Guzmán, L. Sánchez, José Javier Román Gómez, J. Cifrián

引用次数: 3

Sino-Orbital Aspergillosis in a Kidney Transplant Recipient 肾移植受者的眼眶曲霉病

Case Reports in Transplantation Pub Date : 2022-04-14 DOI: 10.1155/2022/5946446

Christian Maalouli, J. de Greef, T. Duprez, A. Devresse, C. Huart, M. Coutel, N. Demoulin, L. Belkhir, N. Kanaan

引用次数: 0

Azole-Induced Myositis after Combined Lung-Liver Transplantation 肺肝联合移植后唑致肌炎

Case Reports in Transplantation Pub Date : 2022-03-25 DOI: 10.1155/2022/7323755

S. Happaerts, Michiel Wieërs, W. Vander Mijnsbrugge, L. Godinas, D. Van raemdonck, L. Ceulemans, R. Vos, G. Verleden

{"title":"Azole-Induced Myositis after Combined Lung-Liver Transplantation","authors":"S. Happaerts, Michiel Wieërs, W. Vander Mijnsbrugge, L. Godinas, D. Van raemdonck, L. Ceulemans, R. Vos, G. Verleden","doi":"10.1155/2022/7323755","DOIUrl":"https://doi.org/10.1155/2022/7323755","url":null,"abstract":"Lung transplant recipients experience a high rate of invasive pulmonary aspergillosis infections, for which voriconazole is the treatment of choice. We report a patient who developed voriconazole-induced myositis that relapsed after one dose of isavuconazole. Our patient was a 38-year-old man who received a single sequential lung transplantation and liver transplantation because of end-stage cystic fibrosis. He presented to our emergency room with acute pain in both forearms at 3 weeks after voriconazole was initiated for invasive pulmonary aspergillosis infection. Levels of voriconazole were normal during the course of therapy. After stopping voriconazole, the symptoms decreased but relapsed after one dose of isavuconazole. Other causes of muscle pain and inflammation were excluded. Magnetic resonance imaging of both arms showed muscle edema in both arms, including involvement of the fascia, consistent with myositis. There were no signs of necrosis. Isavuconazole was discontinued, and the corticosteroid dose was temporarily increased, with rapid resolution of all complaints. Our patient is the fourth reported case of voriconazole-induced myositis, and the first whose symptoms relapsed after initiating isavuconazole.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91160393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0