Case Reports in Transplantation最新文献_第10页

An Atypical Case of Shiga Toxin Producing-Escherichia Coli Hemolytic and Uremic Syndrome (STEC-HUS) in a Lung Transplant Recipient. 肺移植受者发生志贺毒素产生-大肠杆菌溶血性尿毒症综合征(STEC-HUS)的非典型病例。

Case Reports in Transplantation Pub Date : 2019-04-11 eCollection Date: 2019-01-01 DOI: 10.1155/2019/9465040

Louis Manière, Camille Domenger, Boubou Camara, Diane Giovannini, Paolo Malvezzi, Lionel Rostaing

引用次数: 3

Accelerated Oxalosis Contributing to Delayed Graft Function after Renal Transplantation. 加速草化病导致肾移植后移植物功能延迟。

Case Reports in Transplantation Pub Date : 2019-03-25 eCollection Date: 2019-01-01 DOI: 10.1155/2019/8942062

Yvelynne P Kelly, Astrid Weins, Melissa Y Yeung

{"title":"Accelerated Oxalosis Contributing to Delayed Graft Function after Renal Transplantation.","authors":"Yvelynne P Kelly, Astrid Weins, Melissa Y Yeung","doi":"10.1155/2019/8942062","DOIUrl":"https://doi.org/10.1155/2019/8942062","url":null,"abstract":"Hyperoxaluria is an important and underrecognized cause for allograft dysfunction and loss after transplantation. It is potentially treatable if recognized in a timely fashion. Research is ongoing to expand the array of therapeutic options available to treat this. We present a case of a 59-year-old gentleman who underwent deceased donor renal transplantation that was complicated by delayed graft function necessitating continuation of renal replacement therapy. His initial biopsy showed extensive acute tubular necrosis with associated peritubular capillaritis and interstitial nephritis and oxalate crystals in several tubules. Despite receiving methylprednisolone to treat moderate acute cellular rejection, he remained dialysis dependent with minimal urine output. An interval renal allograft biopsy revealed residual acute tubular necrosis with extensive oxalate crystals now visible in many tubules. His plasma oxalate level was concurrently elevated to 19.3 μmol/L (reference range ≤ 1.9 μmol/L). He commenced calcium citrate to manage his hyperoxaluria and ultimately became dialysis independent at 3 weeks after transplantation. This case provides an important example of accelerated oxalate nephropathy as an underappreciated contributor to delayed graft function after renal transplantation. Our accompanying discussion provides an update on current therapeutic measures for managing this challenging condition.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"2019 ","pages":"8942062"},"PeriodicalIF":0.0,"publicationDate":"2019-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/8942062","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37345422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Postinfectious Acute Glomerulonephritis in Renal Transplantation: An Emergent Aetiology of Renal Allograft Loss. 肾移植感染后急性肾小球肾炎:异体肾移植损失的紧急病因学。

Case Reports in Transplantation Pub Date : 2019-03-18 eCollection Date: 2019-01-01 DOI: 10.1155/2019/7438254

Alícia Molina-Andújar, Enrique Montagud-Marrahí, David Cucchiari, Pedro Ventura-Aguiar, Erika De Sousa-Amorim, Ignacio Revuelta, Frederic Cofan, Manel Solé, Adriana García-Herrera, Fritz Diekmann, Esteban Poch, Luis F Quintana

{"title":"Postinfectious Acute Glomerulonephritis in Renal Transplantation: An Emergent Aetiology of Renal Allograft Loss.","authors":"Alícia Molina-Andújar, Enrique Montagud-Marrahí, David Cucchiari, Pedro Ventura-Aguiar, Erika De Sousa-Amorim, Ignacio Revuelta, Frederic Cofan, Manel Solé, Adriana García-Herrera, Fritz Diekmann, Esteban Poch, Luis F Quintana","doi":"10.1155/2019/7438254","DOIUrl":"https://doi.org/10.1155/2019/7438254","url":null,"abstract":"Despite the high incidence of posttransplant infections, postinfectious acute glomerulonephritis (PIAGN) in renal allograft is a rare entity, without effective treatment and a bad prognosis. We describe two cases of PIAGN: the first one was developed 2 years after kidney transplantation, secondary to Staphylococcus aureus bacteremia with presence of extracapillary proliferation in biopsy. The patient was treated with methylprednisolone and plasma exchanges without response, remaining dialysis dependent. The second case was reported 5 years after kidney transplantation, secondary to influenza A infection. Kidney biopsy showed an IgA-dominant PIAGN and methylprednisolone boluses were initiated without clinical response, suffering a progressive worsening and loss of kidney graft. Due to the aggressive clinical course of this entity, PIAGN should be considered in the differential diagnosis of acute kidney graft failure in the context of an infection. Elderly patients have a higher risk of more severe acute renal dysfunction, requiring dialysis in a great proportion of cases.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"2019 ","pages":"7438254"},"PeriodicalIF":0.0,"publicationDate":"2019-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/7438254","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37177079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy. 异戊康唑单药治疗肾移植患者胃粘膜真菌病1例。

Case Reports in Transplantation Pub Date : 2019-03-17 eCollection Date: 2019-01-01 DOI: 10.1155/2019/9839780

Imran Gani, Atbin Doroodchi, Kristina Falkenstrom, Holly Berry, Won Lee, Laura Mulloy, Muhammad Saeed, Rajan Kapoor

{"title":"Gastric Mucormycosis in a Renal Transplant Patient Treated with Isavuconazole Monotherapy.","authors":"Imran Gani, Atbin Doroodchi, Kristina Falkenstrom, Holly Berry, Won Lee, Laura Mulloy, Muhammad Saeed, Rajan Kapoor","doi":"10.1155/2019/9839780","DOIUrl":"https://doi.org/10.1155/2019/9839780","url":null,"abstract":"Gastrointestinal mucormycosis is a rare infection in solid organ transplant recipients. Our patient, a 79-year-old male, presented with severe dysphagia and odynophagia about 2 weeks after receiving a renal transplant. An upper gastrointestinal (UGI) endoscopy revealed esophagitis and gastric ulceration, the cultures from which grew Rhizopus species. A usual treatment strategy should include Amphotericin B as monotherapy or in combination with Posaconazole or Isavuconazole for such infections. Our patient was treated with Isavuconazole monotherapy, in an effort to minimize renal toxicity from Amphotericin B to the new allograft. Unique to our case was a successful clinical response and resolution of UGI lesions with Isavuconazole monotherapy. Due to the vagueness of presenting symptoms, such infections can be easily missed in an immunocompromised patient which can have tragic outcomes. Prompt diagnosis and modulation of immunosuppression are essential to decrease mortality and morbidity. Isavuconazole is a novel agent and can be used as a monotherapy for such infections, especially in renal transplant recipients.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"2019 ","pages":"9839780"},"PeriodicalIF":0.0,"publicationDate":"2019-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/9839780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37170930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Vascular Reconstructions in Living Unrelated Kidney Transplant Using Donor Ovarian Vein and Recipient Inferior Epigastric Artery with Simultaneous Enucleation of a Complex Cyst. 利用供体卵巢静脉和受体腹壁下动脉重建无亲缘关系活体肾移植血管并同时去核复杂囊肿。

Case Reports in Transplantation Pub Date : 2019-03-13 eCollection Date: 2019-01-01 DOI: 10.1155/2019/3272080

Giuseppe Serena, Javier Gonzalez, Giselle Guerra, Mohamed Ammar Al Nuss, Maykel Valdes, Gaetano Ciancio

{"title":"Vascular Reconstructions in Living Unrelated Kidney Transplant Using Donor Ovarian Vein and Recipient Inferior Epigastric Artery with Simultaneous Enucleation of a Complex Cyst.","authors":"Giuseppe Serena, Javier Gonzalez, Giselle Guerra, Mohamed Ammar Al Nuss, Maykel Valdes, Gaetano Ciancio","doi":"10.1155/2019/3272080","DOIUrl":"https://doi.org/10.1155/2019/3272080","url":null,"abstract":"Increasing the organ donor pool and solving the recipient demands continue to be one of the challenges in transplantation. We report our experience in transplanting a living donor kidney requiring complex vascular reconstructions and an enucleation of complex cyst. A 57-year-old male patient underwent a living unrelated kidney transplant. The living donor kidney was procured through a laparoscopic hand-assisted right donor nephrectomy. After vascular stapling, the kidney had a short upper pole arterial branch, a short renal vein (3 mm), and a complex upper pole cyst. The renal vein was elongated using the donor ovarian vein and the short upper pole artery was extended using the recipient inferior epigastric artery and anastomosed to the main renal artery. The renal allograft vessels were anastomosed end-to-side to the external iliac vessels. The complex cyst was removed performing an enucleation with a rim of normal tissue and reconstruction of the calyceal system. This case represents three different surgical reconstructions in order to make the organ available for transplantation. In some circumstances, complex vascular reconstruction of living donor kidney with removal of complex cyst represents a strategy to expand the donor pool.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"2019 ","pages":"3272080"},"PeriodicalIF":0.0,"publicationDate":"2019-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/3272080","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37165422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Unusual Presentation of Hemophagocytic Lymphohistiocytosis in a Kidney Transplant Patient. 肾移植患者异常表现的噬血细胞淋巴组织细胞增多症。

Case Reports in Transplantation Pub Date : 2019-03-10 eCollection Date: 2019-01-01 DOI: 10.1155/2019/3682378

Danwen Yang, Natanong Thamcharoen, Chelsea Marcus, Andreas Varkaris, William Aird, Eliyahu V Khankin, Francesca Cardarelli

引用次数: 5

Deceased Donor Renal Transplantation Combined with Bilateral Nephrectomy in a Patient with Tuberous Sclerosis and Renal Failure. 已故供肾移植联合双侧肾切除术治疗结节性硬化症合并肾功能衰竭1例。

Case Reports in Transplantation Pub Date : 2019-03-06 eCollection Date: 2019-01-01 DOI: 10.1155/2019/2172163

R Novotny, J Chlupac, T Marada, S Bloudickova-Rajnochova, H Vavrinova, L Janousek, J Fronek

{"title":"Deceased Donor Renal Transplantation Combined with Bilateral Nephrectomy in a Patient with Tuberous Sclerosis and Renal Failure.","authors":"R Novotny, J Chlupac, T Marada, S Bloudickova-Rajnochova, H Vavrinova, L Janousek, J Fronek","doi":"10.1155/2019/2172163","DOIUrl":"https://doi.org/10.1155/2019/2172163","url":null,"abstract":"Introduction: A 27-year-old female patient with known tuberous sclerosis complex (TSC), polycystic kidneys with multiple large bilateral angiomyolipomas, and failing renal functions with prehemodialysis values (urea: 19 mmol/L; creatinine: 317 μmol/L; CKD-EPI 0,27) was admitted to our department for pre-renal transplant evaluation. The patient was placed on the transplant waiting list as the living donor did not pass pretransplant workup and was subsequently contraindicated. Patient was placed on the \"cadaverous kidney transplant waiting list\".Method: Computed tomography angiography revealed symptomatic PSA in the right kidney angiomyolipoma (AML). The patient underwent urgent transarterial embolisation of the PSA's feeding vessel in the right kidney AML. Based on the \"kidney transplant waiting list\" order patient underwent a bilateral nephrectomy combined with transperitoneal renal allotransplantation of a cadaverous kidney graft through midline laparotomy, appendectomy, and cholecystectomy.Results: Postoperative period was complicated by delayed graft function caused by acute tubular necrosis requiring postoperative hemodialysis. The patient was discharged on the 17th postoperative day with a good renal graft function. Patient's follow-up is currently 23 months with good graft function (urea: 9 mmol/L; creatinine: 100 μmol/L).Conclusion: Renal transplantation combined with radical nephrectomy provides a definitive treatment for TSC renal manifestations.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"2019 ","pages":"2172163"},"PeriodicalIF":0.0,"publicationDate":"2019-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2019/2172163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"37135347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Pyomyositis in a Patient with IgA Nephropathy and Kidney Transplant. IgA肾病合并肾移植患者的化脓炎。

Case Reports in Transplantation Pub Date : 2019-01-28 eCollection Date: 2019-01-01 DOI: 10.1155/2019/7305683

M Xipell, P Ventura-Aguiar, I Revuelta, M Bodro, F Diekmann

引用次数: 2

Massive Leiomyomatous Uterine Proliferation Following Kidney Transplantation: A Case Report and Literature Review. 肾移植后子宫大量平滑肌瘤增生1例并文献复习。

Case Reports in Transplantation Pub Date : 2018-11-28 eCollection Date: 2018-01-01 DOI: 10.1155/2018/3874937

Emmanuel J Minja, Miguel Tan, Melissa J Gibbs, Marwan M Kazimi, Jonathan C Hundley, Harrison S Pollinger

{"title":"Massive Leiomyomatous Uterine Proliferation Following Kidney Transplantation: A Case Report and Literature Review.","authors":"Emmanuel J Minja, Miguel Tan, Melissa J Gibbs, Marwan M Kazimi, Jonathan C Hundley, Harrison S Pollinger","doi":"10.1155/2018/3874937","DOIUrl":"https://doi.org/10.1155/2018/3874937","url":null,"abstract":"Uterine fibroids are the most common benign uterine tumors affecting > 50% of premenopausal women. The incidence, burden and symptoms from uterine fibroids are higher in women of African descent compared to Caucasians. Despite increasing number of African American females being evaluated for and undergoing kidney transplantation (KT), perioperative management guidelines for uterine fibroids currently do not exist. We present a case of a 40 y/o African American female with known symptomatic uterine fibroids preoperatively and medically managed, who underwent a successful KT and 4 years later progressively developed massive leiomyomatous uterine proliferation, causing a complete lateral displacement of the transplanted kidney with severe hydronephrosis, transplant ureteral obstruction and secondary urinary tract infections with bacteremia. This obstruction required a percutaneous nephrostomy tube placement followed by an interval transabdominal hysterectomy, which was complicated by transplant ureteral transection requiring ureteral reimplantation, resulting in prolonged hospitalization, follow-up and outpatient antibiotic regimen. There is a need for management guidelines for uterine fibroids incidentally encountered during the KT evaluation process to avoid similar preventable post-KT complications in patient populations most commonly affected. Literature review and perioperative management/surveillance strategies are provided.","PeriodicalId":30327,"journal":{"name":"Case Reports in Transplantation","volume":"2018 ","pages":"3874937"},"PeriodicalIF":0.0,"publicationDate":"2018-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1155/2018/3874937","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36835311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Life-Threatening Hypertriglyceridemia in a Patient on Ruxolitinib and Sirolimus for Chronic Graft-versus-Host Disease. 危及生命的高甘油三酯血症患者在鲁索利替尼和西罗莫司治疗慢性移植物抗宿主病。

Case Reports in Transplantation Pub Date : 2018-11-04 eCollection Date: 2018-01-01 DOI: 10.1155/2018/4539757

Allison P Watson, Claudio G Brunstein, Shernan G Holtan

引用次数: 10