Dyes and Pigments最新文献_第9页

Bis(triphenylamine) derivatives: Structure-dependent photophysical properties and electropolymerization ability 双（三苯胺）衍生物：结构依赖的光物理性质和电聚合能力

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-08 DOI: 10.1016/j.dyepig.2025.112811

Kacper Muras, Patrycja Rybak, Sergiusz Napierała, Marcin Hoffmann, Maciej Kubicki, Monika Wałęsa-Chorab

{"title":"Bis(triphenylamine) derivatives: Structure-dependent photophysical properties and electropolymerization ability","authors":"Kacper Muras, Patrycja Rybak, Sergiusz Napierała, Marcin Hoffmann, Maciej Kubicki, Monika Wałęsa-Chorab","doi":"10.1016/j.dyepig.2025.112811","DOIUrl":"10.1016/j.dyepig.2025.112811","url":null,"abstract":"<div><div>The series of bis(triphenylamine)s consisting of different aromatic central cores has been designed and synthesized. This was done to test the dependence of the electrochemical properties and electropolymerization ability on the central core of bis(triphenylamine). It was observed that the compound containing a 1,3-substituted phenylene core most easily electropolymerize on the electrode surface, while dyes containing thiophene and EDOT cores do not undergo electropolymerization. This was further explained by DFT calculations of SOMO orbitals, which revealed that the amount of charge at the 4′ position of the phenyl rings of the triphenylamine group varies depending on the central aromatic core. Electrochromic properties of obtained polymers were also tested. The polymers containing electron-withdrawing groups change their color from red via brown to blue, while the polymers obtained via electropolymerization of phenylene derivatives exhibited colorless↔brown↔blue transition. Electrochromic parameters, such as color contrast, long-term stability, response times and coloration efficiency were also investigated. It was found that the electropolymerized layer of derivative with benzooxadiazole as a central core exhibited the best long term stability and it was able to switch between neutral and oxidized states over 700 cycles without loss in color contrast. It was also observed that the photophysical properties also depend on the central core of the dye. The compounds containing electron-withdrawing cores were found to exhibit solvatochromic properties, while the shift of the emission maxima with the solvent polarity was smaller for compounds containing phenylene groups and negligible for compounds containing thiophene and EDOT cores.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"240 ","pages":"Article 112811"},"PeriodicalIF":4.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143828946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rational design of a red-emitting AIE-ESIPT probe for real-time visualization of lipid droplet dynamics in metabolic stress and ferroptosis 合理设计用于代谢应激和铁下垂中脂滴动态实时可视化的红色发射AIE-ESIPT探针

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-08 DOI: 10.1016/j.dyepig.2025.112823

Haitao Song , Zhuangzhuang Yang , Yile Zhao , Lingyu Liu , Xuanmin Yang , Yanrong Zhang

{"title":"Rational design of a red-emitting AIE-ESIPT probe for real-time visualization of lipid droplet dynamics in metabolic stress and ferroptosis","authors":"Haitao Song , Zhuangzhuang Yang , Yile Zhao , Lingyu Liu , Xuanmin Yang , Yanrong Zhang","doi":"10.1016/j.dyepig.2025.112823","DOIUrl":"10.1016/j.dyepig.2025.112823","url":null,"abstract":"<div><div>Lipid droplets (LDs), central to lipid homeostasis and implicated in metabolic disorders, cancer, and neurodegenerative diseases, urgently require advanced imaging probes to overcome limitations of conventional tools—such as small Stokes shifts, low photostability, and complex washing steps. To address these challenges, we engineered three ESIPT-active fluorescent probes (<strong>HBT-CF<sub>3</sub></strong>, <strong>Al-HBT-CF<sub>3</sub></strong>, <strong>In-HBT-CF<sub>3</sub></strong>) through systematic molecular design. By progressively integrating stronger electron-withdrawing groups into the <strong>HBT</strong> scaffold, we achieved <strong>In-HBT-CF<sub>3</sub></strong>, a red-emitting probe (λ<sub>em</sub>: 620 nm) with a 8038 cm<sup>−1</sup> Stokes shift, 41 % quantum yield, and negligible phototoxicity. Its performance stems from synergistic action between restricted intramolecular rotation and hydrophobic shielding, which reinforce intramolecular hydrogen bonds and suppress non-radiative decay. Demonstrating rapid (<2 min), wash-free LD labeling, <strong>In-HBT-CF<sub>3</sub></strong> enabled real-time tracking of LD dynamics under metabolic stress (starvation/oleic acid) and during ferroptosis, revealing erastin-induced LD accumulation and Fer-1-mediated suppression. This work not only resolves critical drawbacks of existing probes but also establishes a design framework for next-generation imaging tools, advancing mechanistic studies of LD-related pathologies and oxidative stress-driven diseases.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"239 ","pages":"Article 112823"},"PeriodicalIF":4.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143800158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational insights into the photophysical behavior of BODIPY dyes: The impact of substituents on radiative and nonradiative decay pathways 对BODIPY染料光物理行为的计算见解：取代基对辐射和非辐射衰变途径的影响

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-08 DOI: 10.1016/j.dyepig.2025.112824

Peng Cui, Zichao Ling, Zhiwei Li

{"title":"Computational insights into the photophysical behavior of BODIPY dyes: The impact of substituents on radiative and nonradiative decay pathways","authors":"Peng Cui, Zichao Ling, Zhiwei Li","doi":"10.1016/j.dyepig.2025.112824","DOIUrl":"10.1016/j.dyepig.2025.112824","url":null,"abstract":"<div><div>This study provides computational insights into the photophysical behavior of a series of BODIPY derivatives (BDPA:P1–P4) with phenyl, naphthyl, anthryl, and pyrenyl substituents. By employing density functional theory (DFT) and spin-flip time-dependent DFT (SF-TDDFT), we systematically investigated how these substituents modulate the electronic structure, absorption/emission characteristics, and charge transfer processes. Our results reveal that although the BODIPY core predominantly determines the frontier orbital distributions, the nature of the substituents induces systematic shifts in HOMO and LUMO energies, alters charge transfer lengths, and significantly influences the radiative and nonradiative recombination dynamics. Radiative recombination rates correlate strongly with the transition dipole moments, with values ranging from 0.82 × 10<sup>8</sup> s<sup>−1</sup> for BDPA:P3 to 3.81 × 10<sup>8</sup> s<sup>−1</sup> for BDPA:P1. In contrast, nonradiative decay occurs through two competing channels: conical intersections provide an efficient decay pathway for BDPA:P1, BDPA:P2, and BDPA:P3 (with activation barriers between 27.6 and 32.2 kJ/mol leading to decay rates on the order of 10<sup>7</sup> s<sup>−1</sup>), whereas internal conversion becomes more pronounced in BDPA:P4. These findings underscore the potential of substituent engineering to tune the photophysical properties of BODIPY dyes for applications in organic light-emitting diodes (OLEDs) and dye-sensitized solar cells (DSSCs).</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"240 ","pages":"Article 112824"},"PeriodicalIF":4.1,"publicationDate":"2025-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sulfanilic acid assisted-synthesis of nitrogen and sulfur co-doped biomass carbon dots with visible pH response for sensing nitrofuran antibiotics 磺胺酸辅助合成具有可见 pH 值响应的氮硫共掺生物质碳点，用于传感硝基呋喃类抗生素

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-07 DOI: 10.1016/j.dyepig.2025.112819

Ruizhen Guo , Guoqing Deng , Hui Wu , Wenying Fan , Yi Zhang

{"title":"Sulfanilic acid assisted-synthesis of nitrogen and sulfur co-doped biomass carbon dots with visible pH response for sensing nitrofuran antibiotics","authors":"Ruizhen Guo , Guoqing Deng , Hui Wu , Wenying Fan , Yi Zhang","doi":"10.1016/j.dyepig.2025.112819","DOIUrl":"10.1016/j.dyepig.2025.112819","url":null,"abstract":"<div><div>The abuse of antibiotics posed a serious threat to food security and human health, therefore it was of vital importance for fast and sensitive sensing of nitrofuran antibiotics (NFs). In this study, carbon dots materials with bright blue fluorescence were developed by applying an easy hydrothermal method from rapeseed meal assisted by sulfanilic acid. The sulfanilic acid could not only supply N and S elements, but also effectively break the internal robust chemical structure of rapeseed meal. The skillful doping of N and S contributed to a high QY of 32.4 % for 2SRM-CDs. The luminescent sites of 2SRM-CDs changed with pH, and therefore exhibited an interesting visual response to pH variation. Besides, the 2SRM-CDs showed satisfactory sensitivities and selectivities for furazolidone, nitrofurantoin and nitrofurazone with the limits of detection of 0.354 μM, 0.258 μM and 0.327 μM, when their concentrations were 1.0–330 μM, 0.5–260 μM and 0.5–230 μM,respectively. Furthermore, the as-developed sensor could be successfully used to detect NFs in actual samples, which demonstrated potential in fields such as environmental monitoring and food analysis.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"239 ","pages":"Article 112819"},"PeriodicalIF":4.1,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Orthogonal polydiacetylene (PDA) derivatives based optical chemsensors for the selective detection of cyanide 正交聚二乙炔（PDA）衍生物选择性检测氰化物的光学化学传感器

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-06 DOI: 10.1016/j.dyepig.2025.112809

Ke Sun , Zhongquan Zhu , Guowei Li , Yizhi Shao , Heng Xia , Hui Deng , Jianjun Zhang , Jiangang Gao , Gaopeng Shi , Yangyang Xu

{"title":"Orthogonal polydiacetylene (PDA) derivatives based optical chemsensors for the selective detection of cyanide","authors":"Ke Sun , Zhongquan Zhu , Guowei Li , Yizhi Shao , Heng Xia , Hui Deng , Jianjun Zhang , Jiangang Gao , Gaopeng Shi , Yangyang Xu","doi":"10.1016/j.dyepig.2025.112809","DOIUrl":"10.1016/j.dyepig.2025.112809","url":null,"abstract":"<div><div>Due to its widespread usage but high toxicity, the detection of cyanide has drawn special attention. However, in many works usually only one colorimetric or fluorescent detector was put forward for chemical sensing. Here in this contribution, two kinds of polydiacetylene (PDA) derivatives substituted by either <em>o</em>-hydroxybenzaldehyde or dicyanovinyl group were designed and explored for the optical sensing of cyanide. Firstly, these two PDA derivatives were polymerized in the form of vesicle individually and showed chromatic transition from blue to purple or red after the addition of cyanide into the aqueous solution. Then polyvinylidene fluoride membrane was chosen to incorporate the PDAs to form strip-based solid sensors, which could exhibit obvious blue-to-red colorimetric response upon exposure to cyanide aqueous solution with different concentrations in an orthogonal way. Interestingly, these two PDA derivatives remained blue phase in the presence of many common anions, thus demonstrating excellent selectivity for the distinguishment of cyanide. Besides the experimental characterization methods, such as UV–visible absorption and Raman spectroscopy, to study the underlying chemical mechanism, the principal component analysis method was also applied for the multivariate statistical analysis in combination with RGB (Red, Green, Blue) values to obtain a deep insight into the chromatic sensing of PDAs.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"239 ","pages":"Article 112809"},"PeriodicalIF":4.1,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dominos-like crystalline phase transformation of fluorescence emitters bearing energy-boosted structure 带有能量增强结构的荧光发射体的多米诺骨牌状晶体相变

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-06 DOI: 10.1016/j.dyepig.2025.112808

Qiang Zhao , Xun Fu , Lizhu Dong , Zhaocheng Xu , Jinyi Zhang , Xiaojie Cheng , Bai Chen , Jianfeng Zhao , Dongqing Lin , Man Xu , Linghai Xie

{"title":"Dominos-like crystalline phase transformation of fluorescence emitters bearing energy-boosted structure","authors":"Qiang Zhao , Xun Fu , Lizhu Dong , Zhaocheng Xu , Jinyi Zhang , Xiaojie Cheng , Bai Chen , Jianfeng Zhao , Dongqing Lin , Man Xu , Linghai Xie","doi":"10.1016/j.dyepig.2025.112808","DOIUrl":"10.1016/j.dyepig.2025.112808","url":null,"abstract":"<div><div>The exploration of molecular dominos-like crystalline phase transformation, based on π-functional optoelectronic molecules, is promising for smart sensor devices and delivering encryption information. Herein, we report an energy-boosted dominos-like crystalline phase transformation through controlling π···π stacking manners of fluorescent molecules, dimethyl 2,5-bis((2,3,4-trifluorophenyl)amino)terephthalate (234-TFAT). Upon solvent vapor atmosphere and thermal condition, yellow-orange-emitted crystals can realize the chain-like crystalline phase transition, where the molecular stacking areas is decreasing one-third from the standing-state to the lying-state π···π stacking mode. Meanwhile, such lying-state π···π stacking mode can achieve the single molecular emission at 542 nm that blue-shifted from 585 nm under the standing-state stacking mode. On this basis, we test the application in visualizing Morse code for message encrypting and deciphering. This research helps us establish universal design principles with energy-boosted supramolecular dominos-like crystalline phase transformation and provides a novel molecular platform for the multi-stimuli responsive functional materials.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"239 ","pages":"Article 112808"},"PeriodicalIF":4.1,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acid phosphatase detection using a colorimetric probe based on azo compound toward forensic applications for seminal fluid identification 基于偶氮化合物的比色探针检测酸性磷酸酶在精液鉴定中的法医应用

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-06 DOI: 10.1016/j.dyepig.2025.112806

Jéssica Raimundo da Rocha, Marcone Gomes dos Santos Alcântara, Verônica Diniz da Silva, Dimas José da Paz Lima, Josué Carinhanha Caldas Santos

{"title":"Acid phosphatase detection using a colorimetric probe based on azo compound toward forensic applications for seminal fluid identification","authors":"Jéssica Raimundo da Rocha, Marcone Gomes dos Santos Alcântara, Verônica Diniz da Silva, Dimas José da Paz Lima, Josué Carinhanha Caldas Santos","doi":"10.1016/j.dyepig.2025.112806","DOIUrl":"10.1016/j.dyepig.2025.112806","url":null,"abstract":"<div><div>Acid phosphatase (AP) is an enzyme present in various tissues of the human body and is found in high concentrations in seminal fluid. Therefore, it can be easily used as a forensic marker for the presence of semen, assisting criminal investigations and clinical diagnostic tests. This work developed a simple colorimetric method for detecting AP in semen using a probe derived from an azo dye. The proposed method utilizes (<em>E</em>)-4-(phenyldiazenyl)phenyldihydrogen phosphate (AZO1-P) as a substrate, which, upon enzymatic hydrolysis, yields the yellow-colored (<em>E</em>)-4-(phenyldiazenyl)phenol (AZO1) (<em>λ<sub>max</sub></em> = 423 nm). However, for applications involving complex matrices, this coloration is not ideal due to low colorimetric contrast. Thus, a coupling reaction was performed between AZO1 and 4-aminoantipyrine (4-AAP) to improve colorimetric resolution. The product generated provided greater colorimetric contrast (red color, <em>λ<sub>max</sub></em> = 516 nm) and was easily visualized. Under ideal conditions, the method exhibited a linear range of 1–6 U L<sup>−1</sup> for AP, with a detection limit of 0.42 U L<sup>−1</sup> and a relative standard deviation (RSD) of 3 %. Classical AP inhibitors, such as sodium tungstate and molybdate, were evaluated and showed IC<sub>50</sub> values of 11.7 ± 0.5 and 2.9 ± 0.7 mM, respectively. In addition, the method was applied to real samples and against possible interferents that can be found at sex crime scenes, proving to be sensitive and selective for detecting AP in semen (from 1000-fold dilution). Finally, the proposed method can be used for the quantitative and qualitative detection of AP in the laboratory and the field as an alternative to presumptive tests in forensic sciences associated with sex crimes.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"239 ","pages":"Article 112806"},"PeriodicalIF":4.1,"publicationDate":"2025-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143816045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A multifunctional ratiometric fluorescence sensing platform for Salicylaldehyde, DPA, Al3+, and Pb2+ in water samples 水样中水杨醛、DPA、Al3+和Pb2+的多功能比例荧光检测平台

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-05 DOI: 10.1016/j.dyepig.2025.112810

Huijun Li , Xiaoqin Feng , Xiang Liu , Junjun Sun , Jianchao Shi , Zhanguo Li , Zhouqing Xu , Yan Wang

{"title":"A multifunctional ratiometric fluorescence sensing platform for Salicylaldehyde, DPA, Al3+, and Pb2+ in water samples","authors":"Huijun Li , Xiaoqin Feng , Xiang Liu , Junjun Sun , Jianchao Shi , Zhanguo Li , Zhouqing Xu , Yan Wang","doi":"10.1016/j.dyepig.2025.112810","DOIUrl":"10.1016/j.dyepig.2025.112810","url":null,"abstract":"<div><div>Developing multifunctional sensing platform for recognizing various toxic substances in water samples is essential for public safety. Salicylaldehyde is widely used in fine chemicals such as spices, pharmaceuticals, pesticides, dyestuffs and metal chelating agents. 2, 6-pyridinedicarboxylic acid (DPA), the main component of bacterial spores, is regarded as the most important biomarker for anthrax detection. Excessive exposure to Al<sup>3+</sup> is associated with health risks such as Alzheimer's and Parkinson's diseases. Pb<sup>2+</sup>, a significant environmental pollutant, can lead to various health issues including muscle paralysis, anemia, and memory and mental health concerns. This work develops a dual-emission hybrid <strong>SiQDs@ZIF-8@Eu<sup>3+</sup>@HPU-14</strong> for ratiometric detection of SA, DPA, Al<sup>3+</sup> and Pb<sup>2+</sup>. Due to the enhanced emission at 484 nm and quenched emission at 618 nm, <strong>SiQDs@ZIF-8@Eu<sup>3+</sup>@HPU-14</strong> has a low detection limit of 138 nM for SA. Besides, the emission at 618 nm could be enhanced by trace DPA and quenched by large concentration of DPA (LOD = 0.637 nM). The addition of Al<sup>3+</sup> and Pb<sup>2+</sup> in <strong>SiQDs@ZIF-8@Eu<sup>3+</sup>@HPU-14-SA</strong> solution could bring about distinct fluorescence responses, allowing the ability of <strong>SiQDs@ZIF-8@Eu<sup>3+</sup>@HPU-14-SA</strong> to distinguish Al<sup>3+</sup> (LOD<sub>Al3+</sub> = 321 nM) and Pb<sup>2+</sup> (LOD<sub>Pb2+</sub> = 158 nM). Furthermore, a logical gate system and sensing film as well as a new microfluidic sensor-array platform were designed, offering intelligent and portable sensing prospects. This work introduces innovative ideas for synthesizing sophisticated hybrid materials with integrated sensing functionalities applied in water environment.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"240 ","pages":"Article 112810"},"PeriodicalIF":4.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143815959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly sensitive colorimetric and fluorescence “Turn On” sensing of hydrazine via restriction in intramolecular vibrations of AIEE active fluorophore 通过限制AIEE活性荧光团的分子内振动对肼进行高灵敏度比色和荧光“开启”感应

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-05 DOI: 10.1016/j.dyepig.2025.112813

Sidra Saeed , Kainat Khurshid , Mohammed A. Assiri , Alam Shabbir , Sohail Anjum Shahzad

{"title":"Highly sensitive colorimetric and fluorescence “Turn On” sensing of hydrazine via restriction in intramolecular vibrations of AIEE active fluorophore","authors":"Sidra Saeed , Kainat Khurshid , Mohammed A. Assiri , Alam Shabbir , Sohail Anjum Shahzad","doi":"10.1016/j.dyepig.2025.112813","DOIUrl":"10.1016/j.dyepig.2025.112813","url":null,"abstract":"<div><div>Hydrazine (N<sub>2</sub>H<sub>4</sub>), a B2 toxin, harms the environment due to its extensive use in industries. Because of its lethal hypertoxicity and carcinogenicity, there is a crucial need to identify and quantify hydrazine. For this purpose, we developed a colorimetric and fluorometric probe <strong>MFB</strong> for sensitive and selective detection of hydrazine (N<sub>2</sub>H<sub>4</sub>). The mefenamic acid-derived benzamide <strong>MFB</strong> was easily synthesized by coupling reagent through a single step. Fluorescent probe <strong>MFB</strong> shows the extraordinary aggregation-induced emission enhancement (AIEE) characteristics with the formation of aggregates. The DLS analysis was performed to determine the aggregates particle size and interaction with probe <strong>MFB</strong>. The probe <strong>MFB</strong> exhibits a strong emission wavelength at 444 nm in aggregated state. Furthermore, the probe <strong>MFB</strong> has selectively detected the hydrazine (N<sub>2</sub>H<sub>4</sub>) through a blockage of semi-photoinduced electron transfer and restricted intramolecular vibrations mechanism with the lowest possible detectable amount of 47.3 nM. The interaction of <strong>MFB</strong> with hydrazine (N<sub>2</sub>H<sub>4</sub>) was verified by the UV–Visible and <sup>1</sup>H NMR titration experiments. Moreover, theoretical studies like orbitals energy calculation and type of interactions were executed to support the experimental findings. Interestingly, the probe <strong>MFB</strong> was employed in both solution and solid states for the favourable detection of hydrazine (N<sub>2</sub>H<sub>4</sub>) in real-time analysis including drinkable water, beverages, industrial wastewater, soil samples, mung bean sprouts and artificial urine samples.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"239 ","pages":"Article 112813"},"PeriodicalIF":4.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143790891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design and synthesis of a new environmentally sensitive small-molecule fluorescent probe for MRGPRX2 新型环境敏感MRGPRX2小分子荧光探针的设计与合成

IF 4.1 3区工程技术

Dyes and Pigments Pub Date : 2025-04-05 DOI: 10.1016/j.dyepig.2025.112815

Xiaoxue Mo , Yuexin Lv , Jiayu Lu , Yajing Hou , Hua Qian , Cheng Wang , Huaizhen He

{"title":"Design and synthesis of a new environmentally sensitive small-molecule fluorescent probe for MRGPRX2","authors":"Xiaoxue Mo , Yuexin Lv , Jiayu Lu , Yajing Hou , Hua Qian , Cheng Wang , Huaizhen He","doi":"10.1016/j.dyepig.2025.112815","DOIUrl":"10.1016/j.dyepig.2025.112815","url":null,"abstract":"<div><div>MAS-related G protein-coupled receptor X2 (MRGPRX2) is a key target receptor and an important drug target for triggering pseudo-allergic reactions. Studying its ligands will help to understand the mechanism of pseudo-allergic reactions and discover anti-allergic drugs. Small-molecule fluorescent probes are widely used to study the localization of G protein-coupled receptors (GPCRs) on the cell membrane, the transport and internalization of GPCRs, and the interaction between receptors and ligands due to their high selectivity, sensitivity and safety. MRGPRX2 is one of GPCRs with an active hydrophobic ligand binding domain, so designing small-molecule fluorescent probes with environmental sensitivity is very important for the study of MRGPRX2 ligands and the visualization of this receptor. In this study, we selected the agonist of MRGPRX2 (<em>R</em>)-ZINC-3573 as the recognition group and used different fluorophore skeleton structures as the luminescent group to synthesize a series of small-molecule fluorescent probes targeting MRGPRX2. Among them, PoX2-B with BODIPY FL as the fluorescent group had good photostability and environmentally sensitive properties to the hydrophobic ligand binding domain of MRGPRX2, and could be used for living cell imaging. Furthermore, PoX2-B could specifically recognize MRGPRX2, and it was expected to be used to screen effective ligands of MRGPRX2 in the future, so as to play a role in the development of anti-allergy drugs and the pathogenesis of allergic diseases.</div></div>","PeriodicalId":302,"journal":{"name":"Dyes and Pigments","volume":"240 ","pages":"Article 112815"},"PeriodicalIF":4.1,"publicationDate":"2025-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143823731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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