Swiss Archives of Neurology and Psychiatry最新文献

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Protein kinases expressed in aggregating brain cell cultures during myelination. 在髓鞘形成过程中聚集的脑细胞培养物中表达的蛋白激酶。
G C Miescher, V Taylor, L Kappos, J M Matthieu, P Honegger
{"title":"Protein kinases expressed in aggregating brain cell cultures during myelination.","authors":"G C Miescher,&nbsp;V Taylor,&nbsp;L Kappos,&nbsp;J M Matthieu,&nbsp;P Honegger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum-free aggregating rat brain cell cultures provide sufficient cell surface and paracrine interactions between neurons and glial cells for compact myelination. We are interested in the part played in these signalling pathways by protein kinases and have used a PCR cDNA cloning approach to catalogue the protein kinase genes expressed by these cultures. 8 transmembrane protein kinases were identified: IGF1-R, trk B, bFGF-R, c-met, Tyro2, Tyro1, Tyro4 and a novel eck-related gene. The first 4 are receptors for ligands with known trophic functions. Tyro2 is a novel gene related to the EGF-R. The latter 3 belong to the eck gene family of more than 8 highly related putative receptors for, as yet, unknown ligands. 8 cDNAs for intracellular protein kinases were also isolated including 3 novel genes. Ongoing studies are investigating whether these proteins contribute to myelination and/or could be used as therapeutic targets in demyelinating diseases.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 3","pages":"217-21"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18690376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Psychiatry and psychotherapy]. [精神病学和心理治疗]。
W Pöldinger
{"title":"[Psychiatry and psychotherapy].","authors":"W Pöldinger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 4","pages":"371-7"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18695631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human myelin/oligodendrocyte glycoprotein: a new member of the L2/HNK-1 family. 人髓磷脂/少突胶质细胞糖蛋白:L2/HNK-1家族的新成员。
D Burger, A J Steck, C C Bernard, N Kerlero De Rosbo
{"title":"Human myelin/oligodendrocyte glycoprotein: a new member of the L2/HNK-1 family.","authors":"D Burger,&nbsp;A J Steck,&nbsp;C C Bernard,&nbsp;N Kerlero De Rosbo","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 3","pages":"227-8"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18691991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improvement of culture conditions for aggregating brain cells to study remyelination. 改善脑细胞聚集培养条件研究髓鞘再生。
M G Zurich, J M Matthieu, P Honegger
{"title":"Improvement of culture conditions for aggregating brain cells to study remyelination.","authors":"M G Zurich,&nbsp;J M Matthieu,&nbsp;P Honegger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 3","pages":"228-32"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18691992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
8th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Barcelona, Spain, October 23-24, 1992. Abstracts. 欧洲多发性硬化症治疗和研究委员会(ECTRIMS)第8届大会。1992年10月23日至24日,西班牙巴塞罗那。摘要。
{"title":"8th Congress of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS). Barcelona, Spain, October 23-24, 1992. Abstracts.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 4","pages":"293-368"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18695629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Event-related potentials in evaluation of metabolic encephalopathies. 代谢性脑病评价中的事件相关电位。
E Ruzicka, V Tesar, E Jelinkova, M Mmerta, S Nevsimalova, O Kucerova
{"title":"Event-related potentials in evaluation of metabolic encephalopathies.","authors":"E Ruzicka,&nbsp;V Tesar,&nbsp;E Jelinkova,&nbsp;M Mmerta,&nbsp;S Nevsimalova,&nbsp;O Kucerova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Auditory event-related potentials (ERPs) were studied in 28 patients with chronic liver cirrhosis and in 34 patients on regular hemodialysis treatment for chronic renal failure. Prolongation of P3 wave latency was the earliest and most evident sign of brain cognitive dysfunction in both groups. The changes of ERPs well corresponded to the stage of metabolic affliction when, in addition, N1 and N2 wave latencies were delayed in patients with more advanced liver cirrhosis. In the group of hemodialyzed patients, ERPs reflected the effects of an individual treatment procedure as well.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 4","pages":"378-84"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18695632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Revalidation of the Saul and Sheppard "Dream Hostility Counts" in a time series of 24 dreams, of which 7 ended in a migraine at awakening]. [在24个梦的时间序列中重新验证索尔和谢泼德的“梦境敌意计数”,其中7个梦在醒来时以偏头痛告终]。
F Beyme
{"title":"[Revalidation of the Saul and Sheppard \"Dream Hostility Counts\" in a time series of 24 dreams, of which 7 ended in a migraine at awakening].","authors":"F Beyme","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Our Series of 24 dreams can be used for validating hostility scales. Nocturnal migraine represents an ideal archimedian point (C. G. Jung) from which psychology can reach certainties comparable to those of physics. By Pearsons Phi coefficient psychological findings can be solidly moored to the \"non-psychical\", the somatic sphere. Revalidation of the Dream-Hostility-Count lead us to a higher degree of significance (p < 0.005 instead of p < 0.01) than that reached by Saul and Sheppard who used hypertensives for a critical group.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 6","pages":"561-73"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18517971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The family and Alzheimer's disease: making choices]. [家庭和阿尔茨海默病:做出选择]。
O Diener
{"title":"[The family and Alzheimer's disease: making choices].","authors":"O Diener","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 5","pages":"402-11"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18511903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Endocarditis, brain lesions and anticoagulants (anatomic clinical and statistical study of 229 cases)]. 【心内膜炎、脑病变与抗凝剂(229例解剖临床与统计研究】。
P Liard, R Lang, E Wildi
{"title":"[Endocarditis, brain lesions and anticoagulants (anatomic clinical and statistical study of 229 cases)].","authors":"P Liard,&nbsp;R Lang,&nbsp;E Wildi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study of brain autopsy findings in 229 cases of endocarditis (67 anticoagulated, 162 non-anticoagulated) shows that treatment with anticoagulation does not increase the incidence of cerebral hemorrhage, neither from the conversion of ischaemic necroses into hemorrhagic ones nor from an increase in other circulatory or vascular lesions. The analysis was based on the pathogenesis and detailed descriptions of the lesions, paying particular attention to hemorrhagic infarctions of the cerebral cortex. Using chi-square analysis, there was no significant difference between the frequency of lesions in anticoagulated versus non-anticoagulated patients.</p>","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 1","pages":"39-61"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18686419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immune complexes in sera of MS patients: a new strategy of the analysis of their antigen portion. MS患者血清中的免疫复合物:抗原部分分析的新策略。
F Wiederkehr, M R Büeler, R Fried, D J Vonderschmitt
{"title":"Immune complexes in sera of MS patients: a new strategy of the analysis of their antigen portion.","authors":"F Wiederkehr,&nbsp;M R Büeler,&nbsp;R Fried,&nbsp;D J Vonderschmitt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":30134,"journal":{"name":"Swiss Archives of Neurology and Psychiatry","volume":"144 3","pages":"210-2"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18690373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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