{"title":"The Effect of Hawthorn Red Pigment on Meridian Voltage: An Experimental Study on Traditional Efficacy and Modern Application Value.","authors":"Jingke Guo, Zhiwei Lu, Pingfan Rao, Qiang Gao, Shutao Liu, Ling Chen, Yunhui Shan, Shengbin Wu","doi":"10.1089/bioe.2025.0014","DOIUrl":"10.1089/bioe.2025.0014","url":null,"abstract":"<p><strong>Objective: </strong>To observe the effect of hawthorn red pigment (HRP) on meridian voltage in 20 volunteers over a period of 90 days.</p><p><strong>Methods: </strong>The characteristic absorption peak of HRP was determined by ultraviolet-visible spectroscopy full-wavelength absorption analysis scanning, and its solution particle size was measured by Nano-ZS Malvern laser particle size analyzer. Volunteers were required to take a 100 mL HRP solution containing 4.0 g hawthorn powder three times a day after meals. The measurement time for meridian surface voltage was from 09:00 to 11:00 after breakfast, with the first administration at 09:30.</p><p><strong>Results: </strong>HRP had a characteristic absorption peak at 280 nm, and the average particle size was 137.03 ± 1.44 nm. Among the five volunteers who completed the experiment, the spleen meridian had the most significant decompression effect, with the initial voltage dropping from 14.11 to -7.25 mV on the seventh day (<i>p</i> < 0.05). In addition, the heart meridian voltage gained the most within 90 min, reaching 18.55 mV on the 28th day (<i>p</i> < 0.05), while the pericardium meridian had the greatest loss, with the maximum being 9.24 mV on the 28th day (<i>p</i> < 0.05) and 9.36 mV on the 90th day (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>HRP has the effects of activating the heart meridian, boosting the mind, and relieving the pressure of the pericardium meridian. Regular consumption can reduce the stress on the liver, spleen, and kidney meridians, especially with a significant improvement in the spleen meridian within 28 days. This finding is consistent with the traditional efficacy of hawthorn in strengthening the spleen.</p>","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 2","pages":"125-133"},"PeriodicalIF":1.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178733/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-06-09eCollection Date: 2025-06-01DOI: 10.1089/bioe.2025.0035
Michael Levin, Mustafa B A Djamgoz
{"title":"Bioelectricity, Moving On….","authors":"Michael Levin, Mustafa B A Djamgoz","doi":"10.1089/bioe.2025.0035","DOIUrl":"10.1089/bioe.2025.0035","url":null,"abstract":"","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 2","pages":"113-114"},"PeriodicalIF":1.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178721/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-06-09eCollection Date: 2025-06-01DOI: 10.1089/bioe.2025.0001
Fasih Bintang Ilhami, Tutut Nurita, Vivi Azmilah, Azzahra Vima Lika, Erina Maulidatul Komariyah, Hilmatul Aisyiyah, Frengki Adolf Tanaem
{"title":"Investigating the Potential of Marine Animal Bioelectricity as a Basis for Renewable Energy Development.","authors":"Fasih Bintang Ilhami, Tutut Nurita, Vivi Azmilah, Azzahra Vima Lika, Erina Maulidatul Komariyah, Hilmatul Aisyiyah, Frengki Adolf Tanaem","doi":"10.1089/bioe.2025.0001","DOIUrl":"10.1089/bioe.2025.0001","url":null,"abstract":"<p><p>The electrical and magnetic sensory systems of marine animals provide remarkable insights into evolutionary adaptation and their technological potential. This study explores the bioelectric abilities of marine species such as stingrays, electric eels, dolphins, and hammerhead sharks, which utilize specialized organs for hunting, navigation, and self-defense. These adaptations have inspired biomimetic innovations, including underwater navigation devices, bioelectric sensors, and medical diagnostic tools. This study uses a descriptive and qualitative method to show how electroreceptors like the ampullae of Lorenzini help the body pick up on small electric and magnetic fields. These capabilities have significant implications for the development of efficient energy systems, advanced navigation tools, and sensitive medical technologies. However, ethical and ecological challenges arise, especially concerning the conservation of marine species and their habitats. This study highlights the necessity of sustainably integrating biomimetic technologies and promoting further interdisciplinary research to enhance applications while safeguarding marine ecosystems.</p>","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 2","pages":"115-124"},"PeriodicalIF":1.5,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12178732/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-03-18eCollection Date: 2025-03-01DOI: 10.1089/bioe.2024.0028
Nuhan Purali
{"title":"Mechanosensitive Ion Channels: The Unending Riddle of Mechanotransduction.","authors":"Nuhan Purali","doi":"10.1089/bioe.2024.0028","DOIUrl":"10.1089/bioe.2024.0028","url":null,"abstract":"<p><p>Sensation begins at the periphery, where distinct transducer proteins, activated by specific physical stimuli, initiate biological events to convert the stimulus into electrical activity. These evoked pulse trains encode various properties of the stimulus and travel to higher centers, enabling perception of the physical environment. Transduction is an essential process in all of the five senses described by Aristotle. A substantial amount of information is already available on how G-protein coupled receptor proteins transduce exposure to light, odors, and tastants. Functional studies have revealed the presence of mechanosensitive (MS) ion channels, which act as force transducers, in a wide range of organisms from archaea to mammals. However, the molecular basis of mechanosensitivity is incompletely understood. Recently, the structure of a few MS channels and the molecular mechanisms linking mechanical force to channel gating have been partially revealed. This article reviews recent developments focusing on the molecular basis of mechanosensitivity and emerging methods to investigate MS channels.</p>","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 1","pages":"58-70"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054614/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-03-18eCollection Date: 2025-03-01DOI: 10.1089/bioe.2024.0027
Martí Bernaus, Yuly López, Sara M Soto, Adrián Bermúdez-Castel, Jose Antonio Calero, Diego Torres, Margarita Veloso, Lluis Font-Vizcarra
{"title":"Pulse Lavage and Electrical Fields to Remove Biofilms from Cobalt-Chrome Surfaces: An <i>In Vitro</i> Study.","authors":"Martí Bernaus, Yuly López, Sara M Soto, Adrián Bermúdez-Castel, Jose Antonio Calero, Diego Torres, Margarita Veloso, Lluis Font-Vizcarra","doi":"10.1089/bioe.2024.0027","DOIUrl":"10.1089/bioe.2024.0027","url":null,"abstract":"<p><strong>Introduction: </strong>With the increased use of metallic devices in medical disciplines, the number of potential complications has also risen. Orthopedic implant-related infections are a serious complication often requiring a combination of surgical and prolonged antibiotic treatment. Biofilms play an important role in implant-related infections, and many different strategies have been studied to remove it. The purpose of our study was to evaluate the effectiveness of electrical fields and pulse lavage to remove <i>S. epidermidis</i> biofilm from metallic surfaces used in joint arthroplasty.</p><p><strong>Methods: </strong>We compared five different models and combination treatments in an <i>in vitro</i> scenario to remove the biofilm. Five different models were compared with a model without treatment (control): (a) low-pressure pulse lavage, (b) high-pressure pulse lavage, (c) pulsed electrical fields, (d) low-pressure pulse lavage in combination with pulsed electrical fields, and (e) high-pressure pulse lavage in combination with pulsed electrical fields. Electrical fields were applied using 25 pulses at 15 V. Each pulse lasted 0.1 s and was applied every 0.5 s for a total exposure time of 12.5 s. The exposure time for irrigation was set at 25 s.</p><p><strong>Results: </strong>The most effective model for removing biofilm from cobalt-chrome surfaces was a combination of high-pressure pulse lavage and electrical fields.</p><p><strong>Conclusion: </strong>Our study results suggest the use of pulsed electrical fields is effective at removing biofilm and that our tested conditions could be translated to a clinical scenario involving infected medical devices.</p>","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 1","pages":"71-75"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144064861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bioelectronic Therapeutics: A Revolutionary Medical Practice in Health Care.","authors":"Ishu Garg, Madhu Verma, Harish Kumar, Ravi Maurya, Tushar Negi, Prityush Jain","doi":"10.1089/bioe.2024.0039","DOIUrl":"10.1089/bioe.2024.0039","url":null,"abstract":"<p><p>The emerging field of bioelectronic therapeutics unfolds great opportunities for treating numerous neurological and inflammatory conditions by utilizing the amalgamation of molecular medicine, neuroscience, engineering, and computing. These innovative treatments leverage advanced technology to precisely identify, design, and regulate electrical signaling patterns in the nervous system, addressing multiple diseases. Modifying neural signaling patterns to produce therapeutic effects at a particular organ may blur the lines between conventional medical practices. These modify the neurological behavior using electrical, magnetic, optical, and ultrasonic pulses through closed-loop systems to optimize neural behavior. The Food and Drug Administration (FDA) has approved numerous invasive and noninvasive bioelectronic devices, in the treatment of various neuronal diseases and non-neuronal diseases. Furthermore, the FDA has approved many devices for clinical studies. The field of bioelectronics encounters challenges in integrating with the health care system, including incomplete understanding of human nervous anatomy, neuronal function, membrane potential, and technological limitations. This review aims to explore bioelectronics therapeutics, their role or action in challenges to growth and their solutions, and the prospects of bioelectronic therapeutics.</p>","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 1","pages":"2-28"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054615/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-03-18eCollection Date: 2025-03-01DOI: 10.1089/bioe.2025.0015
Dany Spencer Adams
{"title":"My Experiments in Bioelectricity: The Winding Road to Developmental Bioelectricity.","authors":"Dany Spencer Adams","doi":"10.1089/bioe.2025.0015","DOIUrl":"10.1089/bioe.2025.0015","url":null,"abstract":"<p><p>The story of my journey from marine biology to cancer detection by voltage imaging.</p>","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 1","pages":"78-85"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12056574/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-03-18eCollection Date: 2025-03-01DOI: 10.1089/bioe.2024.0042
Mustafa B A Djamgoz, Christopher S Foster
{"title":"The Problem of Diagnosing Prostate Cancer-The Promise of Ion Channels as Novel Biomarkers of Disease!","authors":"Mustafa B A Djamgoz, Christopher S Foster","doi":"10.1089/bioe.2024.0042","DOIUrl":"10.1089/bioe.2024.0042","url":null,"abstract":"","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 1","pages":"76-77"},"PeriodicalIF":1.5,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
BioelectricityPub Date : 2025-03-18eCollection Date: 2025-03-01DOI: 10.1089/bioe.2025.0016
Mustafa B A Djamgoz, Michael Levin
{"title":"Bioelectricity, a Buzzing Field Going Places.","authors":"Mustafa B A Djamgoz, Michael Levin","doi":"10.1089/bioe.2025.0016","DOIUrl":"10.1089/bioe.2025.0016","url":null,"abstract":"","PeriodicalId":29923,"journal":{"name":"Bioelectricity","volume":"7 1","pages":"1"},"PeriodicalIF":1.1,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12054603/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}