International Journal of Pharmacognosy & Chinese Medicine最新文献_第5页

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000230

Jasmeen Syan

引用次数: 0

Cochrane Review of Bioactive Constituents of Phyllanthus emblica Linn. as an Strengthening Preparedness for Health Emergencies to Combat Infectious Pandemics 余甘子活性成分的Cochrane综述。加强突发卫生事件防范，抗击传染病

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000203

A. Anwar

{"title":"Cochrane Review of Bioactive Constituents of Phyllanthus emblica Linn. as an Strengthening Preparedness for Health Emergencies to Combat Infectious Pandemics","authors":"A. Anwar","doi":"10.23880/ipcm-16000203","DOIUrl":"https://doi.org/10.23880/ipcm-16000203","url":null,"abstract":"Traditional System of Medicine or Unani System of Medicines is the nature’s gift to human beings as they promote health and wellbeing in a best of the natural way. These are the System of Medicines that are affordable than conventional medicine, trouble-free to obtain than modern medicine and majority of them are pleasant to consume and these are the key benefits of these scientifically accepted System of Medicines. Unani System of Medicines is having a wealth of herbal medicine and among the divine treasure of herbs Phyllanthus emblica Linn. is a valuable herb. It belongs from the family Euphorbiaceae and this deciduous tree is of medium height, commonly known as Indian gooseberry, emblic myrobalans, and Amla. These species of plant is a native of India but also found in Sri Lanka, Uzbekistan, South East Asia, and China. Phyllanthus emblica is an important herbal drug used in Unani (Graceo - Arab) and other Alternative Systems of Medicine. It is highly nourishing and could be a significant dietary source of vitamin C, amino acids, and minerals. Phyllanthus emblica contains phenolic compounds, tannins, phyllembelin, rutin, phyllembelic acid, curcum-inoids, and emblicol. All parts of the plant are used for medicinal purposes, especially the fruit, which has been used in Unani as a potent ingredient and in traditional medicine for the treatment of several ailments. Phyllanthus emblica shows hepatoprotective, gastroprotective, antidiabetic, hypolipidemic, antibacterial, antiviral, antioxidant, and antiulcerogenic properties. The prime importance of this Cochrane Reviews of Bioactive Constituents of Phyllanthus emblica Linn. Is to access its efficacy as an Strengthening Preparedness for Health Emergencies to combat infectious pandemics on the basis of its potential as an antibacterial, antiviral and antioxidant properties.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"75 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134300727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancement of Aqueous Solubility and Oral Bioavailability of Bcs Class II Drug by Dry Emulsion 干乳剂提高Bcsⅱ类药物的水溶性和口服生物利用度

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000218

Pawar Anil Raosaheb

{"title":"Enhancement of Aqueous Solubility and Oral Bioavailability of Bcs Class II Drug by Dry Emulsion","authors":"Pawar Anil Raosaheb","doi":"10.23880/ipcm-16000218","DOIUrl":"https://doi.org/10.23880/ipcm-16000218","url":null,"abstract":"Liquid emulsions have distinct advantages over other dosage forms by improving oral bioavailability as well as by reducing the side effects. On contrary, liquid emulsion exhibit lack of physicochemical stability and compliance issues. To overcome these problems, dry emulsion formulation recommended. Dry emulsions are formulated by spray drying, evaporation and rotary evaporation. The aim of the present investigation is to improve the dissolution and oral bioavailability of poorly water soluble drug Olmesartan medoxomil by preparing dry emulsion. Olmesartan medoxomil is poorly soluble drug used for treatment of high blood pressure, showing absorption window at stomach and upper part of small intestine. Dry emulsion was ready by victimisation purgative during which drug is very soluble, using poloxamer188 as water soluble carrier and aerosil 200 as an adsorbent. The preferred oils were castor oil, olive oil, soybean oil and isopropyl myristate and polymers were PEG400, Eudragit EPO and Poloxamer 188. Dry emulsion was prepared by spray drying. Dry emulsion was evaluated for drug content, percentage moisture content, aqueous solubility, dissolution study and in-vivo bioavailability study. In vitro drug release of dry emulsion was studied by using USP type II paddle dissolution apparatus. The solubility of the drug was increased with surfactant and polymer at 1:1 ratio. Probable mechanisms of improved solubility were characterized by particle size determination, Differential Scanning Calorimetry (DSC), Powder X-ray Diffractometry (PXRD) and Scanning Electron Microscopy (SEM). This study revealed that solid dry emulsion technique could prove promising for improvement of solubility, dissolution rate and oral bioavailability of Olmesartan medoxomil.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125752896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pharmacognostic Studies on Curcuma Longa 姜黄的生药学研究

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000163

Vijay Danapur

{"title":"Pharmacognostic Studies on Curcuma Longa","authors":"Vijay Danapur","doi":"10.23880/ipcm-16000163","DOIUrl":"https://doi.org/10.23880/ipcm-16000163","url":null,"abstract":"The turmeric (Curcuma longa) plant, a perennial herb belonging to the ginger family, is cultivated extensively in south and southeast tropical Asia. The rhizome of this plant is also referred to as the “root” and is the most useful part of the plant for culinary and medicinal purposes. The most active component of turmeric is curcumin, which makes up 2 to 5% of the spice. The characteristic yellow color of turmeric is due to the curcuminoids. Curcumin is an orange–yellow crystalline powder practically insoluble in water. Turmeric is used as a dietary spice, coloring agent in foods and textiles, and a treatment for a wide variety of ailments. It is widely used in traditional Indian medicine to cure biliary disorders, anorexia, cough, diabetic wounds, hepatic disorders, rheumatism, and sinusitis. Turmeric paste in slaked lime is a popular home remedy for the treatment of inflammation and wounds. For centuries, curcumin has been consumed as a dietary spice at doses up to 100 mg/d. Extensive investigation over the last five decades has indicated that curcumin reduces blood cholesterol, prevents LDL oxidation, inhibits platelet aggregation, suppresses thrombosis and myocardial infarction (MI), suppresses symptoms associated with type II diabetes, rheumatoid arthritis, multiple sclerosis (MS), and Alzheimer’s disease, inhibits human immunodeficiency virus (HIV) replication, enhances wound healing, protects from liver injury, increases bile secretion, protects from cataract formation, and protects from pulmonary toxicity and fibrosis, is an anti-leishmaniasis and an antiatherosclerotic. Additionally, there is extensive literature that suggests that curcumin has potential in the prevention and treatment of a variety of other diseases.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121786001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Biogenic Synthesis, Characterization and Pharmacological Study of Silver Nanoparticles using Enicostema axillare Leaves 竹叶纳米银的生物合成、表征及药理研究

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000152

Murugapandi, A. Muniyappan

引用次数: 2

Global Research on Tinospora cordifolia (Medicinal Plant) with Special Reference to India: A Scientometric Assessment Publications Output during 2001-2016 药用植物Tinospora cordifolia(药用植物)的全球研究(特别参考印度):2001-2016年科学计量评估出版物产出

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000141

Ritu Gupta

{"title":"Global Research on Tinospora cordifolia (Medicinal Plant) with Special Reference to India: A Scientometric Assessment Publications Output during 2001-2016","authors":"Ritu Gupta","doi":"10.23880/ipcm-16000141","DOIUrl":"https://doi.org/10.23880/ipcm-16000141","url":null,"abstract":"The paper examines 865 global and 747 Indian publications on Tinospora cordifolia research, as indexed in international Scopus database during 2001-2016. Indian research output experienced an annual average growth rate of 11.85%, global publication share of 86.36%, international collaborative publication share of 7.50% and qualitative citation impact averaged to 15.15 citations per paper. Pharmacology, toxicology & pharmaceutics, among subjects, accounted for the highest publications share (57.30%) in Indian output, followed by medicine (33.60%), biochemistry, genetics & molecular biology (23.83%), agricultural & biological sciences (16.06%), chemistry (5.62%), immunology & microbiology (4.55%), environmental science (4.28%) and veterinary science (2.95%) during 2001-2016.The top 15 most productive Indian research organizations and the authors collectively contributed 24.23% and 14.73% respectively as their Indian publication share and 42.70% and 16.59% respectively as their Indian citation share during 2001-2016. Among the total Indian journal output with 98.39% Indian share, the top 20 journals contributed 31.32% share to the Indian journal output during 2001-2016. Of the total Tinospora cordifolia Indian research output, the top 18 highly cited publications registered citations from 104 to 1014 and they together received 4110 citations, with 228.33 citations per paper. These 18highly cited papers involved the participation of 72 authors and 33 organizations and were published in 9 journals.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"247 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124283505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Assessment of Acute and 28-Day Sub-Acute Oral Toxicity of a Polyherbal Formulation in Rats 复方制剂对大鼠急性和28天亚急性口服毒性评价

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000200

R. Pandhare

{"title":"Assessment of Acute and 28-Day Sub-Acute Oral Toxicity of a Polyherbal Formulation in Rats","authors":"R. Pandhare","doi":"10.23880/ipcm-16000200","DOIUrl":"https://doi.org/10.23880/ipcm-16000200","url":null,"abstract":"Purpose: Most of these studies are conducted to assess the degree to which substances are toxic (poisonous) for humans, animals or the environment, to investigate the mechanism of toxic chemicals, or to develop new or improved tests for specific types of chemically induced effects. The present study was designed to evaluate the acute and 28 days repeated oral toxicity study of Polyherbal formulation according to OECD guidelines. Materials and Methods: In acute oral toxicity study, Herbal mixture was administered at 2000mg/kg orally and animals were observed for toxic signs at 30 min, 1, 2 and 4 hrs and thereafter once a day for the next 14 days. In repeated dose-28-day oral toxicity study, the animals were divided into four groups of 6 animals each. Group-1 animals served as a control. Group II animals received low dose of herbal mixture 50 mg/kg, Group III animals received middle dose 100 mg/kg and Group IV animals received high dose of 200 mg/kg (orally) once daily for 28 days respectively. Results: The assessment study results showed that neither the acute toxicity study of herbal mixture at the dose level of 2000mg/kg nor the 28 days repeated oral toxicity study produced any toxic signs or mortality during study. In 28 days repeated oral toxicity study, no significant changes were observed in the haematological and biochemical parameters, relative organ weight, gross necropsy and histopathological examination with herbal mixture treatment. Conclusion: The results of the present study suggest that LD50 of newly developed Polyherbal formulation was >2000 mg /kg and the mixture is completely safe and non-toxic for therapy.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114716783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

α-Mangostin-Rich Extract: A Potential Oral Antibacterial Agent Prepared by Green Extraction 富含α-山竹苷的绿色萃取物:一种潜在的口服抗菌剂

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000201

P. Panichayupakaranant

{"title":"α-Mangostin-Rich Extract: A Potential Oral Antibacterial Agent Prepared by Green Extraction","authors":"P. Panichayupakaranant","doi":"10.23880/ipcm-16000201","DOIUrl":"https://doi.org/10.23880/ipcm-16000201","url":null,"abstract":"The purpose of this study was to prepare α-mangostin-rich extract (AME) using a green microwave extraction together with a simple one-step green fractionation method on a hydrophobic resin column. Based on the established method, AME containing 95% w/w α-mangostin content was obtained with an extract yield of 0.46% w/w dry plant powder. In addition, investigation of its antibacterial activity against oral pathogenic bacteria, including Streptococcus mitis, S. mutans, S. pyogenes and Bacillus subtilis, compared with the standard marker, α-mangostin found that AME exhibited strong antibacterial activities, which were equivalent to those of α-mangostin (MICs and MBCs of 0.5-2 and 4-16 µg/mL, respectively). Moreover, AME exhibited equivalent antibacterial activity against Propionibacterium acnes when compared to the pure α-mangostin (MIC and MBC of 2 and 8 µg/mL, respectively). A chemical stability evaluation found that AME was stable through a period of 16 weeks, when kept in a well-closed container protected from light and stored either at 4 ± 2 or 30 ± 2°C. On the other hand, AME was instable when exposed to light after 3 weeks of storage. The stability evaluation under accelerated conditions (75% relative humidity, at 45°C) implied that AME has a shelf-life of at least two years.","PeriodicalId":298121,"journal":{"name":"International Journal of Pharmacognosy & Chinese Medicine","volume":"61 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115616942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Chemical Constituents and Biological Activities of Genus Nepeta (Lamiaceae) from India and Western Himalaya: A Review 印度和西喜马拉雅地区荆芥属植物的化学成分和生物活性研究进展

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000219

R. K. Joshi

引用次数: 0

Solanum Xanthocarpum: A Review 龙葵:综述

International Journal of Pharmacognosy & Chinese Medicine Pub Date : 1900-01-01 DOI: 10.23880/ipcm-16000177

Suresh Joghee

引用次数: 3

International Journal of Pharmacognosy &amp; Chinese Medicine最新文献

International Journal of Pharmacognosy & Chinese Medicine最新文献