Journal of Medical and Biomedical Science最新文献

Relevance Method to Structure of Orthosis 矫形器结构的关联方法

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-37-42

引用次数: 0

Rheologycal Parameters in Patients with Brain Infarct During COVID-19 COVID-19期间脑梗死患者的流变学参数

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-53-66

引用次数: 0

Myocardial Ischemia and Diabet. Approaches and Recomendation 心肌缺血与糖尿病。方法和建议

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-67-92

引用次数: 0

Investigation of Microcirculatory in Resistive Arteries 阻性动脉微循环的研究

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-19-29

引用次数: 0

Details of Laboratory Work for Medical Students 医学生实验室工作细节

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-43-52

{"title":"Details of Laboratory Work for Medical Students","authors":"","doi":"10.51231/2667-9507-2021-001-01-43-52","DOIUrl":"https://doi.org/10.51231/2667-9507-2021-001-01-43-52","url":null,"abstract":"DOI 10.51231/2667-9507-2021-001-01-43-52\u0000\u0000In the modern world of pandemics, a special place is occupied by the problems of education in the field of medicine. In developed countries, medical education remains combined. Practical training of students in the laboratories of the university is very important. The article describes a biochemistry laboratory class protocol. \u0000This protocol is described in order to create an opportunity for students to apply by doing the theoretical concepts underlying biomolecules and vesicles properties, together with the principles of centrifugation and colorimetric methodologies. The aims, objectives, methodology of teaching/learning, and assessment for this laboratory class are indicated. The proposed protocol for a laboratory class described us creates the opportunity for undergraduate students to perform experiments, to reason, and to discuss some related biochemical concepts, namely protein characterization and properties of specific staining reactions; enzyme quantification by enzymatic reaction; composition and biochemical properties of exovesicles; amphiphilic biomolecules properties; and principles and applications of centrifugation methods. This work was supported by Portuguese Ministry of Science and Higher Education (MCES).","PeriodicalId":29748,"journal":{"name":"Journal of Medical and Biomedical Science","volume":"52 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82872859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Some Aspects of Research on Interpersonal Relationships and Motivations of Healthcare Professionals 医疗保健专业人员的人际关系和动机研究的一些方面

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-12-18

引用次数: 0

From Full-Time Traditional Education to a Distant Form Due the Pandemic Caused by COVID-19 由于新冠肺炎大流行，从全日制传统教育到远程教育

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Journal of Medical and Biomedical Science Pub Date : 2020-12-18 DOI: 10.51231/2667-9507-2021-001-01-30-36

{"title":"From Full-Time Traditional Education to a Distant Form \u0000Due the Pandemic Caused by COVID-19","authors":"","doi":"10.51231/2667-9507-2021-001-01-30-36","DOIUrl":"https://doi.org/10.51231/2667-9507-2021-001-01-30-36","url":null,"abstract":"The article presents data on the prerequisites of different countries on the issue of distance education. In the article the percentage valuation of the distance form of education in relation to the full-time traditional form was shown before the pandemic caused by the new coronovirus and after. In connection with the COVID-19 pandemic, a change in these proportions occurred due to an increase in the partial part of distance learning against the background of a suspended full-time traditional education. In a number of countries, distance learning has become the only one, absorbing all other educational approaches and systems. This provided the education system with special significance and attention from state structures and the government. The relevance of the work is caused by the fundamental nature of the issue of education, as such in general and specifically now, in a pandemic situation. Against the background of WHO recommendations on universal social distance and strict restrictions on mass events, which are an integral part of full-time traditional education, the urgency of the emergency transition from full-time traditional education to distance learning is especially great. The relevance of the issue is increasing due to the uncertainty caused by the expectation of the second wave of coronavirus, which is expected in October and coincides with the beginning of the first semester of the 2020/2021 academic year.","PeriodicalId":29748,"journal":{"name":"Journal of Medical and Biomedical Science","volume":"88 1","pages":""},"PeriodicalIF":0.4,"publicationDate":"2020-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81424598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of cathepsins in Alzheimer's disease: A systematic review 组织蛋白酶在阿尔茨海默病中的作用：系统综述

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Journal of Medical and Biomedical Science Pub Date : 2018-06-01 DOI: 10.4314/jmbs.v7i1.1

S. Rastegar, A. Nouri, R. Masoudi, R. Tavakoli

{"title":"Role of cathepsins in Alzheimer's disease: A systematic review","authors":"S. Rastegar, A. Nouri, R. Masoudi, R. Tavakoli","doi":"10.4314/jmbs.v7i1.1","DOIUrl":"https://doi.org/10.4314/jmbs.v7i1.1","url":null,"abstract":"Alzheimer's disease (AD) is a multifactorial disease. In addition to the precipitating of two proteins betaamyloid peptide and neurofebrillary tangles, which are the main mechanisms involved in the pathogenesis ofAD, other factors such as inflammatory mechanisms and changes in lysosomal enzymes play an important part in the pathogenesis of this disease. Increased and decreased lysosomal proteases, such as cathepsin, can lead to functional impairment and gradual death of neurons. The aim of this review was to investigate the role of cathepsins in the pathogenesis of AD. To conduct this review, relevant articles published between 2000 and 2016, and indexed in reliable databases including PubMed, Google Scholar, Scopus and Web of Science were retrieved. After reviewing the articles, 30 articles that directly addressed the subject of this review were included in final analysis. Cathepsins exacerbate intracellular conditions in neurons, by processing beta-amyloid precursor protein and converting it into amyloid beta. They also play a protective role against AD and fight it by catalyzing the decomposition of beta-amyloids and converting them into the cut out forms of the carboxyl C-terminus. In addition, the 24 kDa fragment resulting from the effect of cathepsin D on apolipoprotein E (ApoE) is the second binding to the receptor in the ApoE. This fragment may also be the cause of the pathogenicity of Apo E in AD. Identifying and explaining the mechanisms involved in the pathogenesis of AD can play a significant role in the prevention and treatment of this disease. Since cathepsins play a pivotal role in the decomposition of beta-amyloid and reduction of the risk of AD, further studies can be considered an effective approach to study AD.Journal of Medical and Biomedical Sciences (2018) 7(1), 1 - 10","PeriodicalId":29748,"journal":{"name":"Journal of Medical and Biomedical Science","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42337144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The effects of National Health Insurance Scheme on equity and quality of diabetes care in secondary healthcare facilities in SouthWest Nigeria 国家健康保险计划对尼日利亚西南部二级医疗机构糖尿病护理公平性和质量的影响

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Journal of Medical and Biomedical Science Pub Date : 2018-06-01 DOI: 10.4314/jmbs.v7i1.2

S. Saka, O. T. Fajemirokun

{"title":"The effects of National Health Insurance Scheme on equity and quality of diabetes care in secondary healthcare facilities in SouthWest Nigeria","authors":"S. Saka, O. T. Fajemirokun","doi":"10.4314/jmbs.v7i1.2","DOIUrl":"https://doi.org/10.4314/jmbs.v7i1.2","url":null,"abstract":"There have been concerns about the influence of the National Health Insurance Scheme (NHIS) on equity and quality of diabetes care in many healthcare settings. This study aimed to assess the effects of NHIS onequity and quality of diabetes care (DC) in Nigeria. A prospective cross-sectional study was carried out among 110 (insured n=42, uninsured=68) consenting type 2-diabetics. Diabetic outpatients on oral hypoglycemic drugs, with at least 4 clinic visits prior to the time of the study were consecutively selected at two NHIS accredited public hospitals in Southwest, Nigeria. Patients’ perceptions of equity and quality of DC were assessed using a validated 27 items questionnaire. The medical care and pharmaceutical care in diabetes were independently assessed using medical chart review and a direct observation of dispensing pharmacists’ activities respectively. Chi-squared test was used to determine associations between variables. Majority (61.8%) of the study participants were uninsured. Females (50.9%) were more than the males (49.1%), 40.0% had post-secondary qualifications. The mean ages for the insured and uninsured were 52.02±11.6 and 58.97± 9.3years respectively. The insured and the uninsured differ in their perceptions of drug availability (p<0.001). The pharmacists’ counselling time (p<0.001) differs between the groups. The quality of medical care provided to the diabetics was generally low. The NHIS did not influence the quality of DC, though it may have engendered inequity in pharmaceutical care in the facilities.Journal of Medical and Biomedical Sciences (2018) 7(1), 11 - 21","PeriodicalId":29748,"journal":{"name":"Journal of Medical and Biomedical Science","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42298567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Caregivers’ knowledge of pneumonia and uptake of vaccination in under-five children in Kaduna State, Nigeria 尼日利亚卡杜纳州五岁以下儿童的护理人员肺炎知识和疫苗接种情况

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Journal of Medical and Biomedical Science Pub Date : 2018-06-01 DOI: 10.4314/jmbs.v7i1.5

A. Yahaya, B. Ekpenyong, P. Obegu

{"title":"Caregivers’ knowledge of pneumonia and uptake of vaccination in under-five children in Kaduna State, Nigeria","authors":"A. Yahaya, B. Ekpenyong, P. Obegu","doi":"10.4314/jmbs.v7i1.5","DOIUrl":"https://doi.org/10.4314/jmbs.v7i1.5","url":null,"abstract":"Pneumonia, though very much a preventable disease, still remains a tangible threat to the lives of under-5 children. Caregivers’ knowledge of pneumonia is important in effective management. The study determinedthe reported proportion of childhood pneumonia in Kaduna State and assessed caregivers’ knowledge of pneumonia and uptake of pneumococcal vaccine among under-5 children. The mixed method research approach used 500 caregivers of under-five children in urban and rural communities in Kaduna state. Ethical approval and informed consent of participants was obtained before data collection using a pre-tested semistructured questionnaire and a focus group discussion guide. Chi-square statistical test was used to test for association between variables, while data from the focus group discussion was analyzed using thematic coding process. Most respondents were aware of pneumonia, they had local names for it but majority 340 (68%) had poor knowledge of pneumonia. The overall occurrence of pneumonia as reported by respondents among under-five children was 33 (6.6%). The rate of child pneumococcal vaccine uptake as reported by respondents was 105 (21%), the uptake was significantly more among the urban dwellers (p<0.01). The knowledge of pneumonia and uptake of pneumococcal vaccination was poor. Routine and constant health education of the community members on pneumonia is very necessary to preserve lives of under-5 children in our communities.Journal of Medical and Biomedical Sciences (2018) 7(1), 40 - 48","PeriodicalId":29748,"journal":{"name":"Journal of Medical and Biomedical Science","volume":" ","pages":""},"PeriodicalIF":0.4,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45504235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1