Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference最新文献

{"title":"Cell culture response of synovial fibroblasts to prosthetic metal particles","authors":"R. Mostardi, S. Meerbaum, M. Kovacik, I. Gradisar","doi":"10.1109/SBEC.1996.493276","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493276","url":null,"abstract":"The purpose of this study was to examine the response of the rabbit fibroblasts to varying concentrations of titanium and cobalt-chrome particles. In the five experiments that were carried out, the results were nearly identical. Where the particle concentrations were 1 or 2 particles per cell of Co-Cr or CPTi, there was little or no effect on the cells. This held for cells growing with the metals as well as when the metals were added at cell confluency. When the particle concentrations were 10 or 20 particles per cell of Co-Cr or CPTi, all or nearly all of the cells were killed. This also held for cells growing with the metals as well as when the metals were added at cell confluency. Both Co-Cr and CPTi were equally as lethal in killing the fibroblasts at the concentrations outlined above in both of the experimental designs. Little attention has been paid to the possible role of the fibroblast, and little is known concerning the response in the presence of wear debris particles outlined above in both of the experimental designs.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115026142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a zinc calcium phosphate ceramic system for antibiotic delivery","authors":"A. Lasserre, S. Wowk, D. Mudra, P. K. Bajpai, M. Cranfield","doi":"10.1109/SBEC.1996.493159","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493159","url":null,"abstract":"Sulfadimethoxine (SDM) is an antibiotic commonly used in veterinary medicine. A zinc calcium phosphate ceramic was used to deliver sulfadimethoxine. In-vitro release in 0.1 M sodium bicarbonate was studied over a period of twelve days. Fifty percent of the drug was released by the second day while a slower release of the drug was observed during the next 10 days. Incorporation of sodium bicarbonate into the ceramic resulted in the total release of the drug within two days. Development of a delivery system which would continuously deliver the drug for 10 days to a month could help in facilitating animal care.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"33 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123010552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vibration analysis of a damaged dog bone model","authors":"R. Pidaparti, Yue Lin","doi":"10.1109/SBEC.1996.493283","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493283","url":null,"abstract":"Finite element simulation was carried out on a dog bone model assuming an elliptical bone cross-section. The analysis was carried out for both undamaged and damaged cases with longitudinal as well as cross-sectional microcracks using a general purpose finite element software (Abaqus). It was found that as the damage parameter increased, the bending stiffness decreased. For the same damage parameter, longitudinal damage was more severe than the cross-sectional damage in the case of bending considered in this study. The same results were obtained in the mode shape studies.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115505599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coregistration of PET/MR brain images by multi-feature correlation matching","authors":"C. Lau, T. Adalı, Y. Wang","doi":"10.1109/SBEC.1996.493209","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493209","url":null,"abstract":"Medical images analysis is becoming increasingly important in clinical applications. One of the active research areas in medical image analysis is image coregistration which involves information fusion of tomographic diagnostic images obtained from different modalities. The authors present a novel MRI and PET brain image coregistration technique using binary correlation matching based on multiple image features. A two-feature image is formed by extracting edge and region information from PET and MR images. By unifying the pixel intensities and anatomical information in the PET and MR images, the multi-feature PET and MR images are then cross-correlated to find the minimum mismatch energy which corresponds to best matching transformation. The consistent nature of the misregistration curves and comparative studies show that the authors' matching technique results in a robust and accurate coregistration of MRI and PET images.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129980446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Three dimensional thinning of octree encoded objects","authors":"A. Amini, J. Jagadeesh, B. McGinley","doi":"10.1109/SBEC.1996.493207","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493207","url":null,"abstract":"Describes an efficient thinning algorithm for octree encoded objects. The algorithm takes advantage of special features of the octree data structure to greatly reduce the magnitude of the thinning procedure. Fundamental, optimized, low-level octree processing operations provide fast access to the encoded object data. Preservation of the topological and geometrical properties of the object is insured by strict connectivity and topology preserving constraints. The selection of the octree as the 3-D representation method was based on its emergence as a well organized and highly compressed data structure for three-dimensional data. It has also demonstrated its accessibility to image and object processing algorithms, display techniques and numerical analysis methods. Basic operations, directly applied to the octree encoded data, form the foundation of complex analysis algorithms like thinning.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121211085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pedobarographic gait analysis on male subjects","authors":"J. Ray, D. Snyder","doi":"10.1109/SBEC.1996.493104","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493104","url":null,"abstract":"Numerous studies have been conducted on human and animal walking gait. Recent studies utilize data acquisition systems; such as, force plates, video cameras, tread mills, infrared detection, digital imaging and insole sensors. The pedobarograph fits into the last acquisition method. This study was conducted using a Novell Pedar/sup R/ in-shoe pedobarographic system. The sensors are imbedded between two soft thin pads. The pad covers the bottom of the foot and is inserted into the shoe between the foot and shoe's bottom. Each pad has 99 capacitance sensors connected to a computer data acquisition system. The advantage of this system over similar systems is its ability to map the gait pattern during normal walking conditions. The sensors are externally calibrated and insensitive to temperature changes. These factors make the system ideal for collecting data inside a shoe. A gait study was conducted utilizing the Pedar system to measure walking gait on human male subjects with overpronated (fallen arches) feet. Each subject was evaluated by a podiatrist for foot type characteristics. After each subject was fitted with the sensor pads, they walked a given course five times while data were recorded. The sensor's output data were divided into ten zones or masks and averaged. The divisions included two in the heel, three in the arch, three in the forefoot and two in the toe area. Data analysis examined the masks for the left and right feet separately. The results are presented in the form of graphs and statistical parameters. Various parameters were examined to determine patterns to categorize the extent of overpronation. Some of the parameters examined were the dynamic pressure line, length of contact phase, energy dissipation, bottom of the foot pressure variations and gait velocity. The conclusions drawn from the study are that the degree of pronation can be cataloged using the energy dissipation as it is related to the stride time and the pressure pattern during foot contact. Subjects with overpronation in either foot have a tendency to walk on the medial portion of the foot thereby expending more time and energy in their walking gait.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"162 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115996909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of temperature of sintering of tricalcium phosphate ceramic on the adhesion rate of human monocyte and monocyte derived macrophages","authors":"D. Parsell, H. Benghuzzi, A. Mohamed, M. Tucci","doi":"10.1109/SBEC.1996.493134","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493134","url":null,"abstract":"The objective of this study was to investigate the effect of temperature of sintering of tricalcium phosphate ceramic (TCP) on the adherence and viability of monocyte and monocyte derived macrophages. The monocytes were isolated from human peripheral blood, biotin labeled and seeded at a density of 5/spl times/10/sup 5/ cells/well according to standard laboratory procedures. Cells were considered macrophages after remaining in culture for 24 hours. Cells were then plated in each microtiter well preloaded with TCP of different sintering temperatures (400, 800 and 1150/spl deg/C). At the end of 1, 2, 3 and 7 days the viability and cell number of monocyte or monocyte derived macrophages were determined using an established assay (biotin-labeled-macrophages). Cell number was determined in control wells with known amounts of cell number, a standard curve was generated by plotting absorbance units versus cell number. At the end of each phase, the blocks were collected and prepared for SEM evaluation. The data from this experiment suggest that: (i) monocytes and macrophages are capable of surviving on all different types of blocks tested over a 7 day period, (ii) SEM evaluation of the ceramic blocks showed an increase in the size and number of micro and macropores with time in blocks sintered at 400 and 800/spl deg/C. In contrast, the size and number of pores calculated from representative views of TCP blocks sintered at 1150/spl deg/C were significantly lower than the other two groups. The mechanism of action of these cells toward the aforementioned bioceramic surfaces has to be investigated in a larger scale. Information obtained from this study provided new insights on the interrelationship between bioceramics, temperature of sintering effect, incubation time and the possible cell response during chronic inflammation at the site of implantation.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126608937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The electronic medical record in clinical care","authors":"W. J. Nowack, M. Niccolai","doi":"10.1109/SBEC.1996.493118","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493118","url":null,"abstract":"A patient's medical record contains a large amount of data, which currently is stored in a paper hard copy. This limits its usability and availability in a particular instance of care. Much of the effort in computerizing the medical record has been driven by financial and quality assurance concerns and constraints placed on the data have often derived from the technical limitations of available systems. The requirements for records to be used in clinical care may differ from the priorities currently followed in the medical record.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126166223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of age in brainstem auditory evoked potential monitoring","authors":"M. Fallah Tafti, G. Ravindran","doi":"10.1109/SBEC.1996.493215","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493215","url":null,"abstract":"53 normal adult male subjects were used for analysis in the study reported. While analysing the values, the results were grouped according to the ages <19, <29, <39, <49, and >50. The recording was done for both right and left ears. The average values of the computed results for the right ear is given in a table. The values for the left ear were found to be more or less similar to the right ear. The results show that the absolute latencies of all the peaks except wave IV increase with age. Similarly the interpeak latencies between I-III and I-V show increased values, whereas for III-V, III-IV and IV-V there are decreased values.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130898715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of near threshold contrast visual evoked potentials using coherent detection techniques","authors":"I. Ghaleb, Carlos E. Davila, Richard Srebro","doi":"10.1109/SBEC.1996.493128","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493128","url":null,"abstract":"The detection of near threshold contrast visual evoked potentials was studied using two coherent detection techniques. Both techniques were used to detect the presence of a common but unknown signal on several noisy channels. The first method utilizes the generalized coherence (GC) estimate, while the second method is an eigenvalue based detection method which studies the eigenvalue distribution of the data autocorrelation matrix. Simulation results show the ability of the two methods to detect the steady-state visual evoked potential (SSVEP) at very low SNR corresponding to grating contrasts that are near to psychophysical threshold.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"96 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134023563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}