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Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference最新文献

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Acellular resuscitative compounds 脱细胞复苏化合物
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493299
L. Cerny, E. R. Cerny
{"title":"Acellular resuscitative compounds","authors":"L. Cerny, E. R. Cerny","doi":"10.1109/SBEC.1996.493299","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493299","url":null,"abstract":"There exists a need for a safer efficacious emergency blood substitute for human use when whole blood is unavailable. This substitute should provide an acceptable volume expansion as well as tissue oxygenation delivery without requiring oxygen-enriched mixtures. It would be advantageous if this material could be stored at room temperature in a dehydrated state for prolonged periods of time. During the past several years, it has been possible to achieve these goals using modified hydroxyethyl starches complexed with stabilized hemoglobins. Here, the authors discuss: (1) The synthesis of a modified hydroxyethyl starch to an aldehyde polymer; (2) Two methods to stabilize the tetramers of hemoglobin; (3) The synthesis of polymer-hemoglobin resuscitative compounds. The ultimate goal of this investigation is a personalized blood service in which one would donate one's own blood, have it converted to an acellular compound, and carry it with one in freeze-dried form. It would be ready for use in any emergency just by reconstituting with water.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134218103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biodegradable scaffolds for use in orthopaedic tissue engineering 用于骨科组织工程的可生物降解支架
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493297
K. Athanasiou
{"title":"Biodegradable scaffolds for use in orthopaedic tissue engineering","authors":"K. Athanasiou","doi":"10.1109/SBEC.1996.493297","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493297","url":null,"abstract":"A review of orthopaedic applications and biocompatibility studies of biodegradable polylactic acid, polyglycolic acid and their copolymers is presented. The experimental and clinical uses of polylactic acid-polyglycolic (PLA-PGA) polymers in the field of orthopaedics have seen significant growth recently, especially as fracture fixation devices and scaffolds for tissue ingrowth. Some complications have occasionally been reported following implantation of PLA-PGA biomaterials. Some of these problems may be attributable to biodegradation byproducts, which alter the pH of the environment. It is postulated that since the mechanical and other physical properties of these biomaterials can be appropriately designed within certain ranges, other aspects of orthopaedic medicine-such as soft tissue repair, synthetic grafts, and bone augmentation scaffolds-may be considered candidates of PLA-PGA usage. To this end, the release of bioactive agents may be controlled and delivered in situ according to the needs of the repair tissues.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133115971","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A new hypothesis: inhibitory potentials of the gap-junctional intercellular communication play an important role in the tumorigenesis induced by biomaterials 一个新的假设:细胞间通讯的抑制电位在生物材料诱导的肿瘤发生中起重要作用
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493217
Toshie Tsuchiya, Atsushi Takahara, Stuart L. Cooper, R. Nakaoka, H. Degawa, Akitada Nakamura
{"title":"A new hypothesis: inhibitory potentials of the gap-junctional intercellular communication play an important role in the tumorigenesis induced by biomaterials","authors":"Toshie Tsuchiya, Atsushi Takahara, Stuart L. Cooper, R. Nakaoka, H. Degawa, Akitada Nakamura","doi":"10.1109/SBEC.1996.493217","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493217","url":null,"abstract":"The authors propose a new hypothesis that the inhibitory potentials of intercellular communication play an important role in the tumorigenesis induced by various biomaterials. The authors' study showed that the tumor-promoting activities of biomaterials were caused by some additives, some catalysts, the leachable oligomers and the surface interaction of cells and materials.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133214918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The development of the GEBOD program GEBOD程序的开发
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493162
Huaining Cheng, L. Obergefell, A. Rizer
{"title":"The development of the GEBOD program","authors":"Huaining Cheng, L. Obergefell, A. Rizer","doi":"10.1109/SBEC.1996.493162","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493162","url":null,"abstract":"The Generator of Body Data (GEBOD) program is an interactive computer program that produces human and dummy body dimensional and inertial property data. These data have applicability to the determination of body mass distribution and human body dynamics modeling, and can be specifically formatted for use in the Articulated Total Body (ATB) model, a three-dimensional rigid-body dynamics simulation program. The data sets generated by GEBOD include the body segments' geometric and mass properties, and the joints' locations and mechanical properties. The subject type can be child, adult human female, adult human male, or Hybrid III dummy. The program also supports the construction of data sets for specific individuals by supplying the necessary anthropometric measurements.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"286 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120879036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 34
Analysis of corrosion in stainless steel total hip prostheses 不锈钢全髋关节假体的腐蚀分析
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493099
M. Musolino, F. Pettit, T. Burleigh, H. Rubash, A. Shanbhag
{"title":"Analysis of corrosion in stainless steel total hip prostheses","authors":"M. Musolino, F. Pettit, T. Burleigh, H. Rubash, A. Shanbhag","doi":"10.1109/SBEC.1996.493099","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493099","url":null,"abstract":"Extensive corrosion was observed in a series of twenty stainless steel (SS) femoral hip prostheses (T-28 design, Zimmer Inc.), retrieved between 8 and 20 years after implantation (avg 14 y.) because of aseptic loosening and stem fracture. Corrosion appeared exclusively inferior to the stem collar, and covered, on average, 16% of the stem surface. The corrosion product was compositionally heterogeneous, and contained Fe, Ni, and Cr, as well as nonmetallic elements such as Ca, K, and Cl. The location and morphology of the corrosive damage are indicative of fretting and crevice corrosion. Despite the severity of the observed corrosive damage, each of these stems experienced a long service life.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123631671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
A system for VEP detection and stimulus phase discrimination VEP检测与刺激相位判别系统
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493117
P. Cilliers, A. V. D. van der Kouwe
{"title":"A system for VEP detection and stimulus phase discrimination","authors":"P. Cilliers, A. V. D. van der Kouwe","doi":"10.1109/SBEC.1996.493117","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493117","url":null,"abstract":"The development of a system for detecting the presence and estimating the phase of the visual evoked potential in the electroencephalogram (EEG) of a human subject is presented. The stimulus set consists of several light emitting diodes (LEDs), all flashing at a rate of 10 Hz but with differing phases. The system employs a combination of wavelet prefiltering, harmonic preprocessing, neural network detection and phase discrimination and postprocessing of the neural network outputs. After an initial training period, the system is able to determine from the EEG at which of the LEDs the subject is looking with a rate of error of less than 20% within an interval of 0.8 seconds.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"5 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123505773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Ultrastructural properties of rat tail tendon 大鼠尾腱的超微结构特性
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493275
J. Price, G. Njus, T. Conway
{"title":"Ultrastructural properties of rat tail tendon","authors":"J. Price, G. Njus, T. Conway","doi":"10.1109/SBEC.1996.493275","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493275","url":null,"abstract":"The correlation between the structural hierarchy of soft connective tissues and the structural properties of these tissues continues to be an area of research interest in biomechanics. This paper presents current research to quantify the effects of the structural organization of collagen type I connective tissues on its load bearing function from ultrastructural properties obtained from tensile tests. The aim of the present paper is to determine if the structural properties, specifically the modulus in the high stress region, vary within the fascicle and sub-fascicle organizational level.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121435691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Sampling rates, aliasing, and the analysis of electrophysiological signals 采样率，混叠，和电生理信号的分析
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493260
B. Moon
{"title":"Sampling rates, aliasing, and the analysis of electrophysiological signals","authors":"B. Moon","doi":"10.1109/SBEC.1996.493260","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493260","url":null,"abstract":"Low analog to digital (A-D) sampling rates, including the Nyquist rate, are inadequate for direct display and analysis of many electrophysiological signals (i.e., without inverse Fourier reconstruction). Recent empirical studies have reported some results that do not follow from sampling theory, such as increasing spike frequency with increasing sampling rate, and thus require explanation. This study addresses the effects of A-D sampling rate on the frequency and amplitude of known artificial signals and of electromyograms. A-D sampling rate need not always be a multiple of the upper band limit because electromyograms, and many other electrophysiological signals, do not always contain frequency components near the upper band limit. Rather, sampling rate must be matched to particular signal frequencies. Furthermore, A-D sampling rate has different effects on frequency and amplitude. Higher sampling rates are required for accurate amplitude reproduction than for accurate frequency reproduction. Very high sampling rates significantly bias quantitative results by detecting low-level noise in signals. This bias is exacerbated in taped signals sampled at reduced tape speeds.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126158338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Skin temperature and impedance measurement in ultrasound wound treatment 超声创面处理中皮肤温度和阻抗测量
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493222
W. Shi, M. Schafer, S. Dubin, M. O'Connor, C. Ozturk, Min-Chih Chou
{"title":"Skin temperature and impedance measurement in ultrasound wound treatment","authors":"W. Shi, M. Schafer, S. Dubin, M. O'Connor, C. Ozturk, Min-Chih Chou","doi":"10.1109/SBEC.1996.493222","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493222","url":null,"abstract":"Therapeutic ultrasound has been widely used to treat various diseases including chronic wounds. However, the mechanisms of the ultrasound effects in wound healing and the best regimen of treatment is still unclear. In this study, the authors used skin electrical impedance measurement during ultrasound treatment and detected a fall in local skin impedance under ultrasound while simultaneous temperature measurement did not show any rise. This result supports the non-thermal effects of the ultrasound and indicates that ultrasound may cause changes in permeability, intracellular electrolytes etc.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"131 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124627030","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
A back-propagation neural network model for prediction of loss of balance 基于反向传播神经网络的失平衡预测模型
Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference Pub Date : 1996-03-29 DOI: 10.1109/SBEC.1996.493119
Wenjian Wang, Amit Bhattacharya
{"title":"A back-propagation neural network model for prediction of loss of balance","authors":"Wenjian Wang, Amit Bhattacharya","doi":"10.1109/SBEC.1996.493119","DOIUrl":"https://doi.org/10.1109/SBEC.1996.493119","url":null,"abstract":"Two neural network models were developed for the prediction of postural sway response due to exposure to risk factors including environmental lighting, job-tasks, standing surface firmness, surface oiliness, work load, peripheral vision conditions, age and gender. Variables used to measure the loss of balance were index of proximity to stability boundary and sway length. Tests showed that job-task is the main risk factor that changes the output while there is some impact by age or gender on the outcome of the model. The results from these models can be used to find risk factors that have great impact on loss of balance and therefore can help in designing intervention programs.","PeriodicalId":294120,"journal":{"name":"Proceedings of the 1996 Fifteenth Southern Biomedical Engineering Conference","volume":"3458 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1996-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127506168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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