Zahedan Journal of Research in Medical Sciences最新文献

{"title":"Investigating the Relationships of Adipokines and Cardiovascular Disease Risk Factors with Normal-Weight Obesity Syndrome Among Women","authors":"J. Sajedianfard, M. Alivand, Saeedeh Ahmadi Jokani","doi":"10.5812/zjrms-123783","DOIUrl":"https://doi.org/10.5812/zjrms-123783","url":null,"abstract":"Background: Normal weight obesity (NWO), known as a syndrome, is characterized by normal weight and body mass index (BMI) but high adipose tissue (more than 30%). Objectives: The present study was conducted to investigate the relationship between adipokines and lipid factors as risk factors in cardiovascular diseases (CVDs) and NWO syndrome in women. Methods: In this case-control study, anthropometric data were obtained from 20 - 40-year-old women referring to nutrition and diet clinics in Ahvaz, Iran. Then, based on the inclusion criteria, including normal BMI and no physical or mental illness, the subjects were divided into the NWO (body fat percentage (BF%) > 30) group and the non-NWO (BF% < 30) group depending on their BF%. Twenty blood samples were taken from each group, and their chemerin and adipokine serum levels were measured using both the enzyme-linked immunosorbent assay (ELISA) method with high sensitivity and the sandwich and competitive ELISA techniques. Results: The serum levels of adipokine chemerin and IL-1α, IL-1β, IL-6, and tumor necrosis factor alpha (TNF-α), as well as the serum concentrations of triglyceride (TG), low-density lipoprotein (LDL), and total cholesterol, were significantly higher in the NWO group than in the control group (P < 0.05). Conclusions: The findings of this study indicated a significant correlation between chemerin, adipokines, and lipid factors, as CVD risk factors, and NWO syndrome and fat tissue percentages in women. Therefore, fat tissue measurement is recommended as a more accurate index than BMI in predicting CVDs.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"396 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124647509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ABO and Rh Blood Groups with Helicobacter pylori Seropositivity in Gonabad City, Iran: A Case-Control Study","authors":"Alireza Mohammadzadeh, M. Minooeianhaghighi, M. Ghorbani, Behdad Zibaee, J. Hajavi","doi":"10.5812/zjrms-123100","DOIUrl":"https://doi.org/10.5812/zjrms-123100","url":null,"abstract":"Background: Helicobacter pylori infection is one of the most common chronic bacterial infections in humans, affecting large populations worldwide. Objectives: The aim of this study was to investigate the relationship between H. pylori infection prevalence with ABO and Rh blood groups. Methods: This descriptive-analytical study was conducted with a case-control design on individuals with anti-H. pylori positive test. Patients with IgG pylori were included in the study based on the inclusion criteria. The individuals were divided into two groups based on antibody titer. The case group included subjects with positive serological results with a titer greater than 12 u/mL IgG, and the control group entailed subjects with negative serological results with a titer less than 8 u/mL IgG. The ABO and Rh blood groups of both groups were examined based on case information. Finally, the data were entered into the SPSS software, and a significance level of 5% was considered for all analyses. Results: According to the results of this study, there was no significant relationship between the blood group and H. pylori infection (P > 0.05). However, the prevalence of blood type A was significantly higher in individuals with positive H. pylori IgG test. Conclusions: The current study suggests no association between ABO and Rh groups, but people with A blood group infected with H. pylori need more attention.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127833039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice of COVID-19 in the General Population of the Southeastern Region in Iran","authors":"N. Noori, Alireza Teimouri, M. Khalili, T. Boryri","doi":"10.5812/zjrms-127345","DOIUrl":"https://doi.org/10.5812/zjrms-127345","url":null,"abstract":"Background: It is necessary to determine the knowledge, attitudes, and practices (KAP) of the coronavirus disease 2019 (COVID-19) epidemic for good management and intervention. Objectives: The current study aimed to evaluate the KAP of the public population regarding COVID-19 in the southeastern region of Iran. Methods: A self-constructed questionnaire based on the literature was developed. The items were asked from the participants via a telephone interview in Zahedan, Iran, during September and October 2020. This study evaluated the association of demographic and socioeconomic information using KAP scales. The data were analyzed using SPSS software (version 20.00). A significance level of 0.05 was considered for the study. Results: A total of 524 participants accepted to have an interview via telephone in the study. About 17% and 10.10% of the participants had poor and excellent knowledge, respectively. Moreover, 72.9% and 66.6% of the respondents had good knowledge and attitude, respectively. The practice was good in 42.4%of the participants. Overall, 73.3% of the subjects had good KAP. Gender had a significant association with attitude toward COVID-19 (χ2 = 18.85; P < 0.001). Place of living did not have any significant association with all scales and overall KAP. Marital status had a significant association with attitude (χ2 = 15.89; P = 0.003), practice (χ2 = 9.60; P = 0.048), and KAP (χ2 = 18.64; P < 0.001) of COVID-19. Education had a significant association with attitude (χ2 = 19.58; P = 0.012), practice (χ2 = 20.26; P < 0.001), and KAP (χ2 = 28.98; P < 0.001) regarding COVID-19. Occupation had a significant association with knowledge (χ2 = 26.94; P < 0.001), practice (χ2 = 15.65; P = 0.017), and KAP (χ2 = 22.29; P < 0.001) regarding COVID-19. Conclusions: The majority of the participants had great knowledge, a positive state of attitude, and acceptable practice. Although the findings are reasonable, it is recommended that the public should proceed to reinforce knowledge, attitude, and practice regarding COVID-19.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"88 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132851678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Crimean-Congo Hemorrhagic Fever in Kermanshah (2006 - 2020)","authors":"M. Zamanian, Roghayeh Nouri, M. Shirvani, Zeinab Mohseniafshar, R. Miladi, R. Mehdizad, S. Yavari","doi":"10.5812/zjrms-128662","DOIUrl":"https://doi.org/10.5812/zjrms-128662","url":null,"abstract":"Background: Crimean-Congo hemorrhagic fever (CCHF) is a contagious viral disease that can be transmitted through various means, including tick bites, contact with infected blood and animal tissues in slaughterhouses, and healthcare-related infections. Methods: In this study, we examined the incidence of CCHF and analyzed the demographic and clinical data of 130 patients diagnosed with CCHF in Kermanshah, a city located in western Iran, over a period of 15 years (2006 - 2020). Results: During the study, 19 cases tested positive, 66 were verisimilar, and the remaining cases (31.54%) were considered suspected. Among the positive cases, 15 patients recovered, and four died. Of those infected, 63.16% were males residing in rural areas. Additionally, 78.95% of the infected individuals had contact with domestic livestock, 26.31% had a history of contact with ticks, and 10.53% had contact with raw meat or raw liver. Furthermore, 5.26% had a history of contact with a CCHF patient. Conclusions: The highest prevalence of CCHF was observed among men aged 15 to 30 who lived in rural areas. According to the annual reports of people suffering from CCHF, health authorities should prioritize this disease in their public health programs. Since individuals who come into direct contact with livestock and livestock products are at a high risk of contracting diseases, it is important to educate them.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"55 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116061347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Failure to Thrive and Associated Risk Factors in In-patients Under 5 Years of Age","authors":"M. Khalili, Alireza Teimouri, Masroor Babaeian","doi":"10.5812/zjrms-121896","DOIUrl":"https://doi.org/10.5812/zjrms-121896","url":null,"abstract":"Background: Failure to thrive (FTT) is defined as delaying or stopping a child’s growth and mightlead to more serious complications, such as reduced learning ability, mental or physical disability, and mortality. Objectives: The present study aimed to assess the prevalence of growth retardation in children under 5 years of age and its risk factors. Methods: This cross-sectional study was conducted on all 2038 children admitted to Ali Ebne Abitalib and Ali Asghar hospitals in Zahedan, Iran, in 2016. The samples entered the study based on census sampling, and the children’s height, weight, and other growth indices were measured. The children with confirmed growth retardation were recognized as the case group. Other children were regarded as controls. The parents’ characteristics were recorded in a list provided for this purpose. Data analysis was performed with SPSS software (version 20) using logistic regression with an error level of 0.05. Results: Of all children, 52.6% were male. The mean age of the total patients was 17.6 ± 4.14 months. The prevalence of children with growth failure was 747 patients (36.6%). In this study, the prevalence of short stature was significantly associated with factors such as parental height, low household level of education, high patients’ birth order, dry feeding, low birth weight, place of residence, and presence of background disease (P < 0.05). Nevertheless, the prevalence of short stature was not significantly associated with gender, age, polygamy status, age of complementary feeding, and gestational age (P > 0.05). Conclusions: The present study concluded that the prevalence of FTT was high due to socioeconomic factors in the studied society. Parental short stature, education, nutrition, low birth weight, and residence in rural areas were the most significant factors.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126322944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Misdiagnosis During the COVID-19 Pandemic: A Case of Lymphoma Initially Diagnosed as Coronavirus Infection","authors":"Pouria Sobhanian Kafshgarkolaee, A. Bakhshipour, H. Ghazvini, Seyedeh Masoumeh Seyedhosseini Tamijani, Azar Ramezani, Raheleh Rafaiee","doi":"10.5812/zjrms-127103","DOIUrl":"https://doi.org/10.5812/zjrms-127103","url":null,"abstract":"Introduction: During the coronavirus disease 2019 (COVID-19) pandemic, physicians delivered a leading part and carried a high work volume, leading to burnout, which subsequently compromised patient safety, decreased the quality of care, and increased misdiagnosis. In the course of the COVID-19 pandemic, physicians should have been vigilant and informed about the potential conditions resulting in medical errors. Particularly, epidemics of infectious illnesses can cause serious challenges in lymphoma diagnosis. Case Presentation: This case report presents a patient with lymphoma presenting with cough, fever, shortness of breath, and a history of contact with her family members who tested positive for COVID-19, which caused delayed diagnosis and treatment, disease progression, and finally, the death of the patient. In the course of the COVID-19 pandemic, the center of attention was detracted from other possible diagnoses, thereby missing lymphoma as a potentially treatable disease. Conclusions: Although physicians are required to be watchful for COVID-19 amid the pandemic, it is also necessary not to neglect other diseases. A delay in the initiation of cancer therapy, even for one month, has been reported to increase the risk of mortality by approximately 10%.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130437626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Persian Version of Measure of Insight into Cognition Self-report (MIC-SR) in Patients with Schizophrenia","authors":"S. Mazhari, Farzaneh Jahanbakhsh, Somaye Soliemanizadeh, Farzaneh Raaii","doi":"10.5812/zjrms-126567","DOIUrl":"https://doi.org/10.5812/zjrms-126567","url":null,"abstract":"Background: Measure of insight into cognition self-report (MIC-SR) has been designed for the assessment of insight into cognitive deficits in schizophrenia, focusing on the areas with known impairment, including memory, problem solving, and attention. Objectives: The current work strives to put the concurrent validity and reliability of the Persian version of MIC-SR to the test. Methods: The standard forward-backward method was utilized for translating the MIC-SR from English to Persian. In total, 66 individuals received the Persian version of the MIC-SR (33 schizophrenia patients), the interview-based cognition assessment (Schizophrenia Cognition Rating Scale (SCoRS)), and a standardized performance-based cognitive battery (the brief assessment of cognition in schizophrenia (BACS)). Coronbach’s alpha was used for the calculation of internal consistency, while intercorrelations among the MIC-SR subscales were calculated as well. Then, Pearson correlations were calculated between the MIC-SR subscales and SCoRS and BACS for the purpose of examining the validity. Results: The Cronbach’s alpha value obtained for the Persian MIC-SR was 0.83. The entirety of Persian MIC-SR measures was considerably correlated with the SCoRS patient’s rating. Moreover, considerable correlations were found among the WHO-quality of life and Persian MIC-SR subscales of attention and problem solving. However, none of the correlations between the BACS subscales and MIC-SR were significant. Conclusions: The Persian version of the MIC-SR demonstrated satisfying psychometric properties that can assess awareness of cognitive impairments in patients with schizophrenia.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134412368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors of Depression, Anxiety and Stress Symptoms: A Cross-Sectional Study Among Emergency Ambulance Workers in Kelantan, Malaysia","authors":"Wan-Nor-Asyikeen Wan Adnan, Tuan Hairulnizam Tuan Kamauzaman, Engku Ariff Tuan Lonik, Siti Azrin Ab Hamid","doi":"10.5812/zjrms-120737","DOIUrl":"https://doi.org/10.5812/zjrms-120737","url":null,"abstract":"Background: Emergency medical professionals are often associated with poor psychological health, which undoubtedly affects their mental health as well as their work productivity. Objectives: The study aimed to determine the predictors of depression, anxiety, and stress symptoms among emergency ambulance workers in Kelantan hospitals. Methods: This cross-sectional study included 143 emergency medical services (EMS) ambulance workers working at ten government hospitals in Kelantan. Assistant medical officers and nurses were also included in the study, while the respondents who had psychological problems before the study were excluded. Sociodemographic data were collected using a self-reported questionnaire. In contrast, the English version of the Depression, Anxiety, and Stress Scale Version 21 (DASS-21) was used to assess the extent of depression, anxiety, and stress. Logistic regression analysis was used to determine the factors that predict depression, anxiety, and stress among ambulance workers. Results: The respondents ranged from 23 to 59 years old, with a mean (standard deviation) age of 38.27 (7.27). Half of the respondents were in the age group of 30 to 39 years (51.0%). Males numbered 91 (63.6%), and female workers numbered 52 (36.4%). The majority of respondents were married individuals (92.3%), non-smokers (79.0%), and had worked for more than ten years (37.7%). More than ten years of service in EMS was identified as a predictor for depression, anxiety, and stress; low back pain was identified as a predictor for anxiety, and female gender was identified as a predictor for stress. Conclusions: The hospital should pay more attention to the sources of depression, anxiety, and stress experienced by ambulance staff, which must be addressed appropriately.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"175 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124300384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the Preoperative Administration of Fibrinogen on Intraoperative Bleeding in Pelvic Surgeries","authors":"A. Pournajafian, F. Rokhtabnak, Seyed Alireza Seyed Siamdoust, Majid Charousaee","doi":"10.5812/zjrms-110485","DOIUrl":"https://doi.org/10.5812/zjrms-110485","url":null,"abstract":"Background: Orthopedic surgeries are frequently complicated with a high amount of intra-operative hemorrhage, and this bleeding has a direct effect on the results of these operations. Objectives: This study evaluated the effect of preoperative administration of fibrinogen on intraoperative bleeding in pelvic surgeries. Methods: This study was a double-blinded, randomized clinical trial. Forty-two patients were randomly divided into two groups of fibrinogen and placebo. Hemoglobin, platelet, and fibrinogen levels were measured in all patients before surgery. In the intervention group, the patients received 1 gr. of fibrinogen after the induction of anesthesia. In the control group, the patients received the same volume of normal saline. All data on bleeding, transfused blood, blood pressure, duration of surgery, hemoglobin, platelet, and fibrinogen levels were recorded during a 24-hour period after surgery. Results: There was no significant difference in terms of age and sex between the groups (P > 0.05). There was no significant difference between hemoglobin, blood transfusion rate, international normalization ratio (INR), prothrombin time (PT), and partial thromboplastin time (PTT) in the two study groups (P > 0.05). Patients' bleeding rate was significantly lower in the fibrinogen group (1328.57 ± 227.8 mL) than in the placebo group (1610 ± 479.58 mL) (P < 0.05). However, there was no significant difference between serum levels of fibrinogen before and after surgery in both groups (P > 0.05). Conclusions: Although prophylactic injection of fibrinogen did not decrease the rate of blood transfusion to the patients in pelvic surgeries, it resulted in a significant bleeding reduction.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121397501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Eight Weeks of Resistance Training and Testosterone Enanthate Consumption on TNF-α and IL-6 Genes’ Expression in the Kidney Tissue of Female Wistar Rats","authors":"K. Molaei, Sanaz Mirzayan Shanjani, A. Gorzi, Y. Kazemzadeh, A. Banaeifar","doi":"10.5812/zjrms-128011","DOIUrl":"https://doi.org/10.5812/zjrms-128011","url":null,"abstract":"Objectives: This study aimed to evaluate the effect of a testosterone enanthate anabolic steroid on the gene expression of inflammatory factors in the kidney tissue of female rats following eight weeks of resistance training. Methods: Twenty-one female Wistar rats weighing 200 ± 20 g, aged eight weeks, were prepared from the Iran Pasture Institute. Following a week for acclimatization, the rats were randomly divided into three groups: control (n = 7), training + placebo (n = 6), and training + testosterone enanthate (n = 8). Resistance training included five days a week of climbing a 1-meter ladder with 26 stairs while bearing weights and two days of rest. In the first week, the weights were equal to 40% of the rats’ body weight. In the following weeks, the weight was increased by 20% per week. The rats were weighed two times a week. In the testosterone group, the rats were injected with 20 mg of testosterone enanthate thrice a week. Forty-eight hours following the last training session and testosterone injection, kidney tissue samples were collected to determine the gene expression of interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α) using real-time PCR. Results: The results showed that testosterone consumption significantly increased the gene expression of TNF-α and IL-6 in female rats undergoing resistance training (P = 0.001). Conclusions: The findings of this study demonstrated that using testosterone increased inflammatory factors in the kidney tissue of all female Wistar rats.","PeriodicalId":292747,"journal":{"name":"Zahedan Journal of Research in Medical Sciences","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125291912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}