2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)最新文献

Nanotechnology in multimodal theranostic capsule endoscopy 纳米技术在多模态胶囊内窥镜治疗中的应用

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-11-23 DOI: 10.1109/NANO.2017.8117439

S. Cochran, T. Button, B. Cox, D. Cumming, D. Gourevich, H. Lay, H. Mulvana, I. Näthke, F. Stewart

{"title":"Nanotechnology in multimodal theranostic capsule endoscopy","authors":"S. Cochran, T. Button, B. Cox, D. Cumming, D. Gourevich, H. Lay, H. Mulvana, I. Näthke, F. Stewart","doi":"10.1109/NANO.2017.8117439","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117439","url":null,"abstract":"Video capsule endoscopy (VCE) has become a clinically accepted diagnostic modality in the last 20 years and has established a technological roadmap for other capsule endoscopy (CE) devices, incorporating microscale technology, a local power supply and wireless communication. However, VCE does not provide a therapeutic function and research in therapeutic capsule endoscopy (TCE) has been limited. This paper proposes a new route towards viable TCE based on multiple CE devices including essential nanoscale components. A first device is used for multimodal diagnosis, with quantitative microultrasound as a complement to video imaging. Ultrasound-enhanced fluorescent marking of sites of pathology allows follow-up with a second device for therapy. This is based on fluorescence imaging and ultrasound-mediated targeted drug delivery. Subsequent treatment verification and monitoring with a third device exploits the minimally invasive nature of CE. Clinical implementation of a complete patient pathway remains the subject of research but several key components have been prepared in early prototype form. These are described, along with gaps that remain to be filled.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121810060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Zero-valent iron based nanoparticles selectively inhibit cancerous cells through mitochondria-mediated autophagy 零价铁纳米颗粒通过线粒体介导的自噬选择性抑制癌细胞

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-11-21 DOI: 10.1109/NANO.2017.8117431

D. Shieh, Li‐Xing Yang, Wei‐Ting Lee, Kuang-Jing Huang, Yana Wu, Wu-Chou Su, Dongxiang Chen, B. Tsang

{"title":"Zero-valent iron based nanoparticles selectively inhibit cancerous cells through mitochondria-mediated autophagy","authors":"D. Shieh, Li‐Xing Yang, Wei‐Ting Lee, Kuang-Jing Huang, Yana Wu, Wu-Chou Su, Dongxiang Chen, B. Tsang","doi":"10.1109/NANO.2017.8117431","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117431","url":null,"abstract":"How to improve the selectivity and efficacy of anticancer agents and to reduce side effects has always been a big challenge in clinical cancer therapy. Chemotherapeutic agents are usually toxic to both cancer and normal tissues, thus rendering compromised overall clinical outcome. Here we developed zero-valent iron nanoparticles (ZVI NPs) that exhibited selectivity toward higher toxicity to most cancerous cells thus opening a new era of anti-cancer therapy or adjuvant therapy through a novel molecular signaling pathway. We used head-and-neck cancer (HNC) cells and ovarian cancer (OVCA) cells to test the anti-cancer properties of ZVI NPs. The ZVI NPs served as a strong reactive oxygen species (ROS) inducer and caused irreversible mitochondria membrane potential lost in sensitive cancer cells that lead to cancer cell autophagy and growth suppression, while not significantly affect normal cell population. Further, the cytotoxicity of the ZVI NPs is highly depended on its redox state as oxidation of the NPs upon aging reduced their cytotoxic potency. In vivo study revealed a dose dependent tumor size reduction in tumor-bearing mice model without significant weight loss and pathological signs. These results suggest that ZVI NPs may serve as a new class of anticancer agent for a wide spectra of neoplastic diseases.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127892852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Graphene for surface enhanced Raman scattering (SERS) molecular sensors 石墨烯用于表面增强拉曼散射(SERS)分子传感器

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-11-21 DOI: 10.1109/NANO.2017.8117453

Ying-Ren Chen, W. Chen, Y. Tzeng

引用次数: 1

Synthesis of high-strength and electronically conductive triple network gels with self-healing properties by the restraint method 用约束法合成具有自愈性能的高强度导电三网凝胶

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-11-21 DOI: 10.1109/NANO.2017.8117472

Shunsuke Nagahama, Kayo Migita, S. Sugano

引用次数: 0

Fabrication and test of a tube shaped e-skin sensor on a colon simulator 管状电子皮肤传感器在结肠模拟器上的制造与测试

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-11-21 DOI: 10.1109/NANO.2017.8117307

Yuhang Sun, Jing Bai, Debao Zhou

{"title":"Fabrication and test of a tube shaped e-skin sensor on a colon simulator","authors":"Yuhang Sun, Jing Bai, Debao Zhou","doi":"10.1109/NANO.2017.8117307","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117307","url":null,"abstract":"Thin film stretchable sensors are believed to have great applications on devices with curved surface. Among them, electrical skin (e-skin) sensors for pressure measurement have the potential to provide protection to human body by feeding back the contact pressure. One of the applications is to monitor the contact pressure from colonoscope to the colonic wall during a colonoscopy to prevent perforation and hemorrhaging. Many researches have been reported about highly flexible and stretchable e-skin sensors. However, no effort has been made to investigate its performance in a colon simulator. In this work, we developed a new technique to make ultra-thin, highly stretchable electrodes on thin films. Then we successfully built a three-layer tube shaped tactile sensor with high conformability and stretchability. We then investigated the pressure generated by various bending curvatures on a colonoscope. Finally, we performed a real-time pressure measurement with the whole sensing system on a fake colonoscope in a colon-simulator. The measured pressure was obtained and visualized on a computer screen. These experiments validated the applicability of the designed sensor and revealed the actual stress distribution on a tube shaped e-skin sensor array in a colon-simulator. This research could be the starting point of the effort on upgrading the strategies of colonoscopy for safer operations and could provide new routines to optimize tactile sensor design for other medical applications.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131118210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A method for quantitative real-time evaluation of measurement reliability when using atomic force microscopy-based metrology 一种基于原子力显微镜的计量时测量可靠性的定量实时评估方法

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-07-25 DOI: 10.1109/NANO.2017.8117292

A. Gujrati, S. Khanal, T. Jacobs

{"title":"A method for quantitative real-time evaluation of measurement reliability when using atomic force microscopy-based metrology","authors":"A. Gujrati, S. Khanal, T. Jacobs","doi":"10.1109/NANO.2017.8117292","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117292","url":null,"abstract":"In atomic force microscopy (AFM) and metrology, it is known that the radius of the scanning tip affects the accuracy of the measurement. However, most techniques for ascertaining tip radius require interruption of the measurement technique to insert a reference standard or to otherwise image the tip. Here we propose an inline technique based on analysis of the power spectral density (PSD) of the topography that is being collected during measurement. By identifying and quantifying artifacts that are known to arise in the power spectrum due to tip blunting, the PSD itself can be used to determine progressive shifts in the radius of the tip. Specifically, using AFM images of an ultrananocrystalline diamond, various trends in measured PSD are demonstrated. First, using more than 200 different measurements of the same material, the variability in the measured PSD is demonstrated. Second, using progressive scans under the same conditions, a systematic shifting of the mid-to-high-frequency data is visible. Third, using three different PSDs, the changes in radii between them were quantitatively determined and compared to transmission electron microscopy (TEM) images of the tips taken immediately after use. The fractional changes in tip radii were detected; the absolute values of the tip radii could be matched between the two techniques, but only with careful selection of a fitting constant. Further work is required to determine the generalizability of the value of this constant. Overall, the proposed approach represents a step towards quantitative and inline determination of the radius of the scanning tip and thus of the reliability of AFM-based measurements.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"41 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125576386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Optimization of experimental parameters for fabrication of atomic junctions using ground-state searches of Ising spin computing 利用伊辛自旋计算的基态搜索优化原子结的实验参数

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-07-25 DOI: 10.1109/NANO.2017.8117331

S. Sakai, Y. Iwata, Y. Katogi, M. Shiomura, Y. Kihara, M. Ito, J. Shirakashi

引用次数: 0

Energy harvesting from ambient light using PVDF with highly conductive and transparent silver nanowire/PEDOT:PSS hybride electrodes 利用具有高导电性和透明银纳米线/PEDOT:PSS混合电极的PVDF从环境光中收集能量

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-07-25 DOI: 10.1109/NANO.2017.8117272

Marco R. Bobinger, Stefan Hinterleuthner, M. Becherer, Sherif Keddis, N. Schwesinger, P. Lugli

引用次数: 3

Effect of low-energy electron beam irradiation on the current-voltage characteristics of single-walled carbon nanotube field effect transistors 低能电子束辐照对单壁碳纳米管场效应晶体管电流-电压特性的影响

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-07-25 DOI: 10.1109/NANO.2017.8117335

D. Choi, G. Mallick, S. Karna

{"title":"Effect of low-energy electron beam irradiation on the current-voltage characteristics of single-walled carbon nanotube field effect transistors","authors":"D. Choi, G. Mallick, S. Karna","doi":"10.1109/NANO.2017.8117335","DOIUrl":"https://doi.org/10.1109/NANO.2017.8117335","url":null,"abstract":"We have performed a series of electrical characterizations on single-walled carbon nanotube (SWCNT) bundle-field effect transistors (FETs) pre- and post-irradiation with low-energy electron beam of 2.5 KeV via scanning electron microscope (SEM). The devices were configured in a geometry where a bundle of SWCNT of approximately 50 nm in diameter was placed across two gold contacts. Current-voltage (I-V) sweep was performed by placing probes on two gold contacts and running a sweep under the gate voltages (Vg) of 0 to 500 mV in 100 mV increments. The characterization shows that our device behaves as a symmetric semiconducting device. In addition, we observe hysteresis behavior between I-V curves under pre-andpost-electron beam irradiation for 30 seconds. We observe that immediately after irradiating our device under the SEM, the maximum current value is lower across the device compared to pre-irradiation value. Furthermore, I-V sweep 17 hours post-irradiation shows higher maximum current value compared to the initial, pre-irradiation value. This behavior of decreased, then increased current values also demonstrate a possible rectifying characteristic of the SWCNT bundle FET device. Additionally, we performed I-V sweep from 0 to 5 V under various gate biases of 0 to 500 mVs. The data reveals that at Vg = 200 mV, there is a sharp break in the current value that is not rectified. The SEM image post-measurement confirms that SWCNT bundle has been completely removed due to the short circuiting of the device during I-V sweep under high gate bias condition. The results presented in this proceeding may prove valueable in research and development of single, as well as bundled SWCNT miniaturized electronic devices and the effects of low-energy radiation on them.","PeriodicalId":292399,"journal":{"name":"2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO)","volume":"470 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133350103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

3D ReRAM arrays and crossbars: Fabrication, characterization and applications 3D ReRAM阵列和横梁:制造，表征和应用

2017 IEEE 17th International Conference on Nanotechnology (IEEE-NANO) Pub Date : 2017-07-25 DOI: 10.1109/NANO.2017.8117387

G. Adam, Bhaswar Chrakrabarti, H. Nili, B. Hoskins, M. Lastras-Montaño, A. Madhavan, M. Payvand, A. Ghofrani, K. Cheng, L. Theogarajan, D. Strukov

引用次数: 8