Gaziantep Medical Journal最新文献_第4页

Middle aortik sendromla ilişkili CHARGE sendromu

Gaziantep Medical Journal Pub Date : 2012-03-01 DOI: 10.5455/GMJ-30-2012-74

A. İrdem, Osman Başpınar, Mehmet Kervancioğlu, Metin Kılınç

{"title":"Middle aortik sendromla ilişkili CHARGE sendromu","authors":"A. İrdem, Osman Başpınar, Mehmet Kervancioğlu, Metin Kılınç","doi":"10.5455/GMJ-30-2012-74","DOIUrl":"https://doi.org/10.5455/GMJ-30-2012-74","url":null,"abstract":"CHARGE syndrome is a rarely encountered syndrome characterized by eye and ear anomalies, as well as cardiac defects, genital hypoplasia, coanal atresia, and brain anomalies. Multidisciplinary approach is mandatory in such patients. In particular, detailed cardiac and ophthalmologic examination should be performed, and the patient should be evaluated in terms of audiometric test and genital organs. A two-month-old baby was brought to our clinic with weakness, fatigue, irritability, vomiting, feeding difficulty, and rapid respiration picture. On her physical examination, general status was poor; arrhythmia, tachycardia, and gallop rhythm were detected on cardiac examination and a 5-6 cm hepatomegaly was detected on abdominal examination. In chest radiograph revealed cardiomegaly; In electrocardiography (ECG) revealed atrial flutter attacks with 1:1 rhythm; transthoracic echocardiography revealed dilated cardiomyopathy (EF; 35%, FS; 16%), aortic coarctation in the aortic arch and in the thin, classical part of descending aorta (mean gradient; 30-35 mmHg), and fine patent ductus arteriosus. During the catheterization, tubular hypoplasia of the aortic arch and istmic aortic coarctation, and hypoplasia was observed in the thoracic and abdominal aorta. The patient was considered to have middle aortic syndrome. Moreover, ocular coloboma and retardation of growth and development were identified in the patient. Cardiac and ophthalmic signs together with the signs of retardation of growth and development were considered probable CHARGE syndrome according to the diagnostic criteria reviewed in 2003. Dilated cardiomyopathy secondary to aortic coarctation is a common condition. Dilated cardiomyopathy improves with appropriate and effective therapy. The prevalence of concurrency of CHARGE syndrome and congenital cardiac disease is 60-70%. Different pictures of congenital cardiac disease can be seen. We, here, introduced a case considered to have CHARGE syndrome together with middle aortic syndrome, the concurrency of which has been seen very little.","PeriodicalId":290827,"journal":{"name":"Gaziantep Medical Journal","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125235266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Gonartrozda farklı eklem içi ilaç uygulamalarının antioksidan sistem ve lipid peroksidasyonu üzerine etkisi

Gaziantep Medical Journal Pub Date : 2012-02-01 DOI: 10.5455/GMJ-30-2011-55

Ahmet Aslan, N. Aydoğan, M. Ilhan, R. A. Özerdemoğlu, I. Altuntaş, H. Yorgancıgil

{"title":"Gonartrozda farklı eklem içi ilaç uygulamalarının antioksidan sistem ve lipid peroksidasyonu üzerine etkisi","authors":"Ahmet Aslan, N. Aydoğan, M. Ilhan, R. A. Özerdemoğlu, I. Altuntaş, H. Yorgancıgil","doi":"10.5455/GMJ-30-2011-55","DOIUrl":"https://doi.org/10.5455/GMJ-30-2011-55","url":null,"abstract":"Oksidatif stres ve lipid peroksidayonu diz osteartrinin (gonartroz) patogenizinde rol oynayabilir. Bu calismada, osteoartritli dizlerde lipid peroksidasyonu ve antioksidan savunma sisteminin hastalik mekanizmasindaki rolu ve farkli eklem ici tedavilerin lipid peroksiyonu ve antioksidan enzim aktivitesi uzerine etkilerini arastirdik. Amerikan Romatoloji Koleji olcutlerine gore gonartroz tanisi alan 75 hasta rastgele esit 5 gruba ayrildi. Birinci gruba sadece eklem ici serum fizyolojik verilerek kontrol grubu kabul edildi. Ikinci gruba yuksek molekul agirlikli hyaluronik asit (HA, hylan G-F 20) eklem ici haftada bir uc kez uygulandi. Ucuncu gruba metil prednizolon asetat bir kez eklem ici verildi. Dorduncu gruba dusuk molekul agirlikli HA, hyaluronan eklem ici haftada bir bes kez uygulandi. Besinci gruba tenoksikam bir kez eklem ici verildi. Eklem sivisi ve hemolizatta serbest radikallerin lipid peroksidasyon urunu malondialdehit (MDA) ve antioksidan enzimler; superoksit dismutaz (SOD), katalaz (CAT), glutatyon peroksidaz (GSH-Px) duzeyleri tedavi oncesi ve sonrasinda olculerek karsilastirildi. Farkli eklem ici uygulamalarla tedavi sonrasi her bir grupta sinovial sividaki MDA duzeylerinin kontrol grubuna gore anlamli duzeyde azaldigi tespit edildi. Hemolizat MDA, SOD, GSH-Px ve CAT seviyelerinde tedavi oncesine gore anlamli fark gozlenmedi. Sinoviyal sivida CAT aktivitesine rastlanmadi. Sinoviyal sividaki SOD ve GSH-Px aktivitelerinde tedavi oncesine gore artis goruldu fakat bu artis istatistiksel olarak anlamli degildi. Gonartroz tedavisinde farkli eklem ici uygulamalar sinoviyal sivida lipid peroksidasyonunu azaltabilir. Gelecekte, gonartrozda tedavinin etkinligini degerlendirmede klinik olcutlere ek olarak MDA gibi biyokimyasal olcumlerin de rutin olarak kullanilabilmesine yonelik daha ileri arastirmalar yapilabilir.","PeriodicalId":290827,"journal":{"name":"Gaziantep Medical Journal","volume":"97 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130017231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Famotidine-induced acquired long QT syndrome: a case report 法莫替丁致获得性长QT综合征1例

Gaziantep Medical Journal Pub Date : 2012-02-01 DOI: 10.5455/GMJ-30-2011-64

E. Tekbaş, Z. Arıtürk, H. Çil, Y. Islamoğlu

引用次数: 2

Gardner-Diamond sendromu: olgu sunumu

Gaziantep Medical Journal Pub Date : 2012-02-01 DOI: 10.5455/GMJ-30-2011-54

Perihan Öztürk, Y. Akman, H. Sayar

引用次数: 0

Symptomatic ossification of the ligamentum flavum at lumbar spine with radiological demonstration: a rare case - 腰椎黄韧带症状性骨化伴放射学表现:一例罕见病例

Gaziantep Medical Journal Pub Date : 2012-02-01 DOI: 10.5455/GMJ-30-2011-60

A. Mete, Ruveyda Olmez, A. Ozkur, M. Bayram

引用次数: 1

Cancer risk factors and factors affecting cancer awareness 癌症危险因素和影响癌症意识的因素

Gaziantep Medical Journal Pub Date : 2012-02-01 DOI: 10.5455/GMJ-30-2011-61

Mustafa Yildirim, C. Parlak, M. Yıldız, Hakan Demirci, H. Çetin, Bilge Akgül, Özet Kanser

{"title":"Cancer risk factors and factors affecting cancer awareness","authors":"Mustafa Yildirim, C. Parlak, M. Yıldız, Hakan Demirci, H. Çetin, Bilge Akgül, Özet Kanser","doi":"10.5455/GMJ-30-2011-61","DOIUrl":"https://doi.org/10.5455/GMJ-30-2011-61","url":null,"abstract":"Kanser bir hucre klonunun kontrolsuz buyumesi ve koken aldigi organa ve diger organlara invazyon ve metastazi ile karakterize bir hastalik gurubudur. Kanser tum dunyada mortalitenin onemli nedenlerinden birisidir. Ortalama yasam suresinin artmasi, gelistirilen yeni tani testleri ile erken evredeki olgu sayisinin artmasi, tarama programlari, tedavideki gelismeler nedeniyle kanser insidensi artmaktadir. Kanser insidensindeki bu artis onemli mortalite ve tedavi maliyetine yol acmaktadir. Bu calismamizin amaci, bireylerde kanser farkindaligina etki eden faktorleri ve bilinen karsinojenlere maruzuyetin sikliginin belirlenmesidir. Bu calisma Antalya Muratpasa Belediyesi calisanlariyla kanser farkindaligini etkileyen faktorleri ve bilinen risk faktorlerinin sikligini belirlemek icin yapilan tanimlayici bir calismadir. Calismamiza 1800 belediye calisanindan onam alinan 1163 calisan katildi. Katilimcilarin 186'si (%16) kadin, 977'si (%84) ise erkekti. Katilimcilarin ortalama yasi 40,2±10 idi. Kadinlarin hem meme kanseri konusunda farkindaliklari dusuk seviyededir, hem de tarama oranlari yetersizdir. Degisen toplumsal yapi ve gelisen iletisim teknolojileri kanser tarama programlarinda goz onunde bulundurulmalidir. Ornegin internet hem egitim hem de bilgilendirme amacli daha fazla kullanilmalidir. KETEM'lerin bilinirliginin az oldugu gorulmektedir. KETEM'lerin tanitimin daha fazla yapilmasi gerektigini dusunuyoruz. Kanserle mucadelede bireylerin risk faktorlerinin belirlenmesinin ve farkindaliklarinin arttirilmasinin onemli oldugunu dusunuyoruz.","PeriodicalId":290827,"journal":{"name":"Gaziantep Medical Journal","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117018522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

The diagnostic and interventional procedures performed in Angiography Laboratory of Pediatric Cardiology Section 在小儿心脏科血管造影实验室进行的诊断和介入程序

Gaziantep Medical Journal Pub Date : 2011-04-01 DOI: 10.5455/GMJ-30-2011-45

A. Irdem, O. Başpınar, M. Kervancıoğlu, M. Kılınç

{"title":"The diagnostic and interventional procedures performed in Angiography Laboratory of Pediatric Cardiology Section","authors":"A. Irdem, O. Başpınar, M. Kervancıoğlu, M. Kılınç","doi":"10.5455/GMJ-30-2011-45","DOIUrl":"https://doi.org/10.5455/GMJ-30-2011-45","url":null,"abstract":"Our aim was to compare the diagnostic and interventional procedures performed in our clinic and evaluate the increase in number and diversity of interventional procedures. Between July 2003 and May 2011 medical records of 1989 patients on whom diagnostic and interventional procedures had been performed was examined. 1036 of the patients (52%) were female and 953 of the patients (48%) were male. Diagnostic procedures were performed in 998 (50.2%) patients, while interventional procedures were performed in 991 (49.8%) patients. The interventional procedures are coil occlusion for patent ductus arteriosus, trans-catheter closure of atrial septal defect, pulmonary balloon valvuloplasty for pulmonary stenosis, aortic coarctation angioplasty, pericardiocentesis for pericardial effusion, aort balloon valvuloplasty for valvular aortic stenosis, permanent and temporary pacemaker insertion for acquired or congenital third degree atrioventricular block and /or sinus node disfunction in 321 (16.1%), 210 (10.6%), 146 (7.3%), 50 (2.5%), 45 (2.3%), 42 (2.1%), 40 (2%) and 33 (1.6%) patients; retrospectively. Interventional procedures were performed in 2,4 and 35 patients in 2003, 2004, and 2005; respectively. Following Angiography Laboratory of Pediatric Cardiology Section set up, interventional procedures were performed in 234 and 439 patients in 2009 and 2010; respectively. Number and variety of interventional procedures have been increased over the years after increased experience of Angiography Laboratory of Pediatric Cardiology Section. Diagnostic angiography procedures have been decreasing over the years by increase in development of new devices and progress of use of interventional treatment techniques. Therefore, interventional procedures have been replaced by diagnostic procedures.","PeriodicalId":290827,"journal":{"name":"Gaziantep Medical Journal","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133581534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paraquat intoxication: a case report - 百草枯中毒1例报告

Gaziantep Medical Journal Pub Date : 2011-04-01 DOI: 10.5455/GMJ-30-2011-49

S. Eraybar, A. Köse, F. Ozdemir, A. Aydin

引用次数: 1

Clinical profile of childhood focal epilepsies in Jordan 约旦儿童局灶性癫痫的临床概况

Gaziantep Medical Journal Pub Date : 2011-04-01 DOI: 10.5455/GMJ-30-2011-48

Wael H Khreisat

{"title":"Clinical profile of childhood focal epilepsies in Jordan","authors":"Wael H Khreisat","doi":"10.5455/GMJ-30-2011-48","DOIUrl":"https://doi.org/10.5455/GMJ-30-2011-48","url":null,"abstract":"Bu calisma, cocukluk cagi fokal epilepsilerin bazal profilini ortaya koymak icin yapildi. Bu calismaya katilan olgular, Urdun'de Kralice Rania Cocuk Hastanesi Pediatrik Noroloji Klinigi'ne basvuran 2 yas uzeri fokal epilepsili cocuklardi. Yas, cinsiyet, nobet tipinin detayi, ilk uyarilmamis nobet yasi, nobetlerin aile hikayesi, febril nobetlerin hikayesi, etyolojik, sosyoekonomik sinif, ilave norolojik bozukluk, elektroensefalografi (EEG) ve beyin goruntuleme bulgulari, ve antiepileptic ilac kullanimi verileri toplandi, sonuclar daha ileriki calisma icin kaydedildi. Bu calismaya total 100 fokal epilepsili vaka alindi, bunlarin 59'u erkekti. Basit parsiyet tip %48'inde, sekonder generalizeli basit parsiyel %17'inde ve kompleks parsiyel nobetler %35'inde kaydedildi. Parsiyel baslangicli nobetlerin pik yaptigi yas 11-14 idi ve kompleks parsiyel nobetler 6-10 yaslari arasindaydi. Yirmi alti hastada epilepsinin aile hikayesi vardi, %91'i dusuk sosyoekenomik siniftandi. Hastalarin %13'unde febril nobet hikayesi varken semptomatik epilepsi %48'inde vardi. Yirmi bes cocuk hipoksik-iskemik ensefalopatiliydi. En yaygin norolojik bozukluk %35 ile ogrenme guclugu idi. EEG %20'inde normaldi ve %68'inde monoterapi kullanildi ve %33'unde kotu kontrol (tedaviye cevap vermeyen) vardi. Bizim ulkemizde fokal epilepsilerin sekli gelismis ulkelerdekinden farkli degildir, etyolojinin belirlenmesi onleme plani icin onemlidir.","PeriodicalId":290827,"journal":{"name":"Gaziantep Medical Journal","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120945406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Laparoscopy-assisted mini-laparotomy: management of a giant (32 cm) ovarian cyst 腹腔镜辅助小剖腹手术:一个巨大(32厘米)卵巢囊肿的处理

Gaziantep Medical Journal Pub Date : 2011-04-01 DOI: 10.5455/GMJ-30-2011-42

Kahraman Ülker, Mehmet Karaca, İsmail Temur, İslim Volkan, Abdülaziz Gül

引用次数: 0