Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons)最新文献_第10页

An Experimental Study on Lipid Metabolism in Rats with Obstructive Jaundice ; Focusing on Cholesterol Synthesis 梗阻性黄疸大鼠脂质代谢的实验研究关注胆固醇合成

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-10-30 DOI: 10.4030/JJCS.36.745

T. Masuda, S. Shiozawa, K. Ogawa

{"title":"An Experimental Study on Lipid Metabolism in Rats with Obstructive Jaundice ; Focusing on Cholesterol Synthesis","authors":"T. Masuda, S. Shiozawa, K. Ogawa","doi":"10.4030/JJCS.36.745","DOIUrl":"https://doi.org/10.4030/JJCS.36.745","url":null,"abstract":"― 745 ― Abstract Aim : The Aim of this experimental study was to investigate how lipid metabolism is altered in a rat obstructive jaundice model, focusing on cholesterol synthesis. Materials and methods : A rat obstructive jaundice model was prepared by bile duct ligation. Rats were sacrificed 1, 2, 3, and 4 weeks after bile duct ligation, and blood was collected, and the total liver was iso-lated. Normal control rats were also sacrificed, and samples were collected in the same manner. The profile of changes lipid metabolism was evaluated over time. Results and discussion : 1) Serum T-Chol level markedly increased at week 1. It subsequently declined, while being higher than the control level until week 4. Serum HDL-C level increased until week 2, and concurrently HMG-CoA reductase activity was elevated. These findings indicate increased hepatic cholesterol synthesis during the early stage of obstructive jaundice. 2) Serum HDL-C level, HMG-CoA reductase activity and LR m-RNA expression level all decreased during the period of complete obstructive jaundice at week 4. At this stage, impaired lipid metabolism and depressed hepatic cholesterol synthesis were observed, and these may be referred to liver disorder due to obstructive jaundice. Conclusion : Thus, lipid metabolism varied in degree of impairment with different stages of obstructive jaundice. Clinically, in the surgery for patients with","PeriodicalId":286696,"journal":{"name":"Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons)","volume":"59 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130555594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Epidermoid Intrapancreatic Accessory Spleen Cyst 胰腺内表皮样副脾囊肿1例

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-10-30 DOI: 10.4030/JJCS.36.861

Yusuke Takahashi, K. Nakagawa, Yukimasa Suzuki, K. Endo, Terutada Kobayashi

引用次数: 0

A Case of Klippel^|^ndash;Weber Syndrome with Congenitally Absent Inferior Vena Cava Klippel^|^ndash;Weber综合征合并先天性下腔静脉缺失1例

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-10-30 DOI: 10.4030/JJCS.36.884

Kumiko Jojima, Y. Koike, M. Niimi

引用次数: 0

Epidermal Growth Factor Receptor（EGFR）遺伝子解析を用い診断した肺癌乳房転移の１例 Epidermal Growth Factor Receptor (EGFR)基因分析诊断的肺癌乳房转移一例

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-10-30 DOI: 10.4030/JJCS.36.781

高橋治海, 山本悟, 石原和浩, 徳山泰治, 水井愼一郎, 二村学

引用次数: 19

Single–Incision Laparoscopically–Assisted Colectomy for Mucinous Cystadenoma of the Appendix: Report of a Case 单切口腹腔镜辅助阑尾粘液囊腺瘤结肠切除术1例报告

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-08-30 DOI: 10.4030/JJCS.36.665

K. Ishibashi, N. Okada, K. Kumamoto, Tomonori Ohsawa, N. Haga, H. Ishida

{"title":"Single–Incision Laparoscopically–Assisted Colectomy for Mucinous Cystadenoma of the Appendix: Report of a Case","authors":"K. Ishibashi, N. Okada, K. Kumamoto, Tomonori Ohsawa, N. Haga, H. Ishida","doi":"10.4030/JJCS.36.665","DOIUrl":"https://doi.org/10.4030/JJCS.36.665","url":null,"abstract":"Received: April 1, 2011/Accepted: May 13, 2011 Correspondence to: Keiichiro Ishibashi Department of Digestive Tract and General Surgery, Saitama Medical Center, Saitama Medical University, 1981 Kamoda, Kawagoe, Saitama 350-8550, Japan Abstract Surgical approaches for an appendiceal mucocele remain controversial, since caution needs to be exercised during surgery to avoid inadvertent rupture of the lesion, which may cause pseudomyxoma peritonei if the lesion is neoplastic. We report a case of mucinous cystadenoma of the vermiform appendix treated successfully by single-incision laparoscopic surgery (SILS). A 71-year-old woman was admitted for the treatment of a cystic mass in the right iliac fossa. Abdominal computed tomography revealed a well-encapsulated cystic mass measuring 30 mm in diameter, adjacent to the cecum. SILS ileocecal resection with lateral-to-medial mobilization and extracorporeal anastomosis was performed via a 3.5-cmlong transumbilical incision. The operative time was 145 minutes and the blood loss was about 10 mL. There were no intraor postoperative complications. The histological diagnosis was mucinous cystadenoma. SILS seems to be a useful option for minimally invasive treatment of appendiceal mucocele, however, as mentioned above, care is needed to prevent complications.","PeriodicalId":286696,"journal":{"name":"Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons)","volume":"abs/1604.04721 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125143862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Serum Integrin β1 Levels as a Prognostic Marker in Metastatic Colorectal Cancer 血清整合素β1水平作为转移性结直肠癌的预后指标

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-08-30 DOI: 10.4030/JJCS.36.594

A. Kogure, N. Saito, Koichi Soyama, Makio Kobayashi, S. Kameoka

{"title":"Serum Integrin β1 Levels as a Prognostic Marker in Metastatic Colorectal Cancer","authors":"A. Kogure, N. Saito, Koichi Soyama, Makio Kobayashi, S. Kameoka","doi":"10.4030/JJCS.36.594","DOIUrl":"https://doi.org/10.4030/JJCS.36.594","url":null,"abstract":"Received: January 7, 2011/Accepted: April 27, 2011 Correspondence to: Akiko Kogure Department of Surgery II, Tokyo Women’s Medical University School of Medicine, 8-1Kawada-cho, Shinjuku-ku, Tokyo 162-8666 , Japan Abstract Aims : In this study, we examined whether the integrin β1 subunit, thought to play an important role in colorectal cancer invasion and metastasis, can be used as a prognostic marker for colorectal cancer. Patients and Methods : The subjects of this study were 86 patients who underwent surgery for colorectal cancer at this department. We measured preoperative serum integrin β1 levels and conducted a 5 year retrospective postoperative study, examining the relationship between integrin β1 levels and survival curves. Results: For patients with postoperative recurrence or metastasis, outcomes were significantly better in those with a preoperative serum integrin β1 level 600 ng/mL than those with <600 ng/mL (p=0.0062). Conclusions: Even in patients with metastases identified preoperatively, outcomes were favourable if preoperative serum integrin β1 levels were high. These results indicate that integrin β1 shows promise as a prognostic marker in metastatic colorectal cancer.","PeriodicalId":286696,"journal":{"name":"Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115345025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Intraoperative Endoscopic Sphincterotomy Using Rendezvous Technique for Choledocholithiasis with Peripapillary Duodenal Diverticula : A Case Report 术中内镜下幽会括约肌切开术治疗十二指肠乳头周围憩室胆总管结石1例

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-08-30 DOI: 10.4030/JJCS.36.645

A. Umemura, A. Sasaki, J. Nakajima, H. Nitta, G. Wakabayashi

引用次数: 1

A Case of Malignant Anorectal Melanoma with Intersphincteric Resection 恶性肛门直肠黑色素瘤伴括约肌间切除术1例

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-08-30 DOI: 10.4030/JJCS.36.675

Shinya U. Amano, S. Fujii, Tsutomu Sato, T. Godai, T. Oshima, C. Kunisaki, A. Nozawa, Y. Rino, M. Masuda, T. Imada

引用次数: 0

Benefits of Introduction of Laparoscopic Appendectomy in a Community Hospital: a Shorter Hospital Stay and Reduced Wound Infection 在社区医院引入腹腔镜阑尾切除术的好处:缩短住院时间和减少伤口感染

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-04-30 DOI: 10.4030/JJCS.36.121

Kojiro Nakamura, M. Sugano

{"title":"Benefits of Introduction of Laparoscopic Appendectomy in a Community Hospital: a Shorter Hospital Stay and Reduced Wound Infection","authors":"Kojiro Nakamura, M. Sugano","doi":"10.4030/JJCS.36.121","DOIUrl":"https://doi.org/10.4030/JJCS.36.121","url":null,"abstract":"AIM: To investigate the benefits of introduction of laparoscopic appendectomy (LA) in a community hospital.PATIENTS AND METHODS: The subjects of the study were 56 patients who underwent appendectomy for acute appendicitis from June 2003 to January 2005 in Kokura Memorial Hospital. Before March 2004, all patients underwent open appendectomy (OA). We introduced LA in April 2004 and from that point onwards almost all the cases underwent LA, except for the initial few cases. Operating time, wound infection, postoperative fever, the time to the first flatus, time of use of postoperative analgesics, and the length of postoperative hospitalization were evaluated.RESULTS: Of the 56 patients enrolled in the study, 35 underwent OA and 21 underwent LA. The operating time for LA was longer than that for OA (mean ± S.D.: 81 ± 37 vs. 58 ± 21 min, p<0.01). However, the rate of wound infection was lower (37% vs. 0%, p<0.01), and the hospitalization was shorter (9.0 ± 6.1 vs. 5.7 ± 3.4 days, p<0.05) for LA. There were no significant differences in other factors.CONCLUSION: The introduction of LA into a community hospital can reduce wound infection and shorten hospitalization. Thus, we recommend use of LA in community hospitals.","PeriodicalId":286696,"journal":{"name":"Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons)","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128146974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

食道アカラシアに対する新しい内視鏡根治術(POEM)の開発开发针对食道acarasia的新内窥镜根治术(POEM)

Nihon Gekakei Rengo Gakkaishi (journal of Japanese College of Surgeons) Pub Date : 2011-04-30 DOI: 10.4030/JJCS.36.245

井上晴洋, 工藤進英

引用次数: 0