Srpski medicinski casopis Lekarske komore最新文献_第8页

European respiratory society practice guidelines in treatment of sarcoidosis: Clinical approach and suggestions 欧洲呼吸学会治疗结节病实践指南:临床方法和建议

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk4-43846

N. Maric, Slobodan Belić, N. Nikolić, M. Stjepanović

引用次数: 1

Modeling as an approach to pandemic uncertainty management: Mortality assessment of the COVID-19 pandemic 建模作为大流行不确定性管理方法:COVID-19大流行的死亡率评估

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk2-33796

A. Stevanovic, Milena Šantrić-Milićević

引用次数: 1

The main features of placental abruption: Clinical presentation and treatment 胎盘早剥的主要特点:临床表现和治疗

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-37202

Sandra Babic, Miljana Z Jovandaric

引用次数: 0

Human immunodeficiency virus infection in pregnancy 妊娠期人类免疫缺陷病毒感染

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk4-42665

R. Sparić, A. Pavić, Luka Andrić, A. Novković, Đina Tomašević, S. Pavić

{"title":"Human immunodeficiency virus infection in pregnancy","authors":"R. Sparić, A. Pavić, Luka Andrić, A. Novković, Đina Tomašević, S. Pavić","doi":"10.5937/smclk4-42665","DOIUrl":"https://doi.org/10.5937/smclk4-42665","url":null,"abstract":"HIV infection represents one of the major global public health challenges, especially among women of reproductive age. In 2020, there were 1.3 million pregnant women infected with HIV worldwide. Untreated HIV infection in pregnancy carries an increased risk of maternal and perinatal morbidity and mortality. Perinatal transmission of HIV refers to the transmission of the virus from mother to child during pregnancy, childbirth, or puerperium. The aim of this paper is to present the up-to-date information on diagnosis, treatment, and monitoring of pregnancy in HIV-positive women, with reference to the time and mode of delivery, in order to prevent the transmission of the virus from mother to fetus. The main goals of monitoring and treating HIV infection during pregnancy are the following: preventing the transmission of the virus to the fetus, preserving the mother's health, and providing conditions for a safe delivery. The goal of treatment is to maintain the lowest level of the virus in the blood, especially at the time of delivery, in order to reduce the risk of vertical transmission. It is recommended to start treatment of HIV infection before pregnancy. Also, regular monitoring of the viral load, the CD4+ lymphocyte count, and blood count, as well as performing liver and kidney function tests, is necessary. The choice of the time and mode of delivery should not differ in pregnant women with a low viral load, as compared to healthy pregnant women, while in pregnant women with a high viral load, the pregnancy should be ended with elective caesarean section. HIV infection affects both the pregnant woman and the fetus. Therefore, antenatal, intrapartum, and postpartum monitoring is important. The decision on therapy, as well as the time and mode of delivery, should be individual, and made in accordance with the viral load, the clinical presentation of HIV infection of the mother, and the condition of the fetus.","PeriodicalId":286220,"journal":{"name":"Srpski medicinski casopis Lekarske komore","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131888501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the relation between the type and titer of antiphospholipid antibodies and the clinical manifestations of antiphospholipid syndrome 抗磷脂抗体的类型和滴度与抗磷脂综合征临床表现的关系探讨

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-32463

D. Stankić, P. Miljić

{"title":"Investigation of the relation between the type and titer of antiphospholipid antibodies and the clinical manifestations of antiphospholipid syndrome","authors":"D. Stankić, P. Miljić","doi":"10.5937/smclk3-32463","DOIUrl":"https://doi.org/10.5937/smclk3-32463","url":null,"abstract":"Introduction: Antiphospholipid syndrome (APS) is an autoimmune disorder manifested by arterial or venous thromboses and/or spontaneous abortions associated with a persistently elevated level of antiphospholipid antibodies. To date, no clear relationship has been established between levels and types of autoimmune antibodies and clinical manifestations of APS, which can range from mild coagulation disorders to life-threatening conditions. Aim: The aim of this study is to examine the relation between antiphospholipid antibody type and titer and the most common clinical manifestations of APS. Materials and methods: The retrospective study included 32 patients with a confirmed laboratory finding of elevated antiphospholipid antibodies, who came for follow-up examinations to the Hemophilia Unit of the University Clinical Center of Serbia, between June 1, 2017 and December 31, 2018. Data on patients were taken from their medical records. Basic demographic data, type and titer of antiphospholipid antibodies, and their association with the present clinical manifestations of APS were analyzed using standard statistical methods. Results: There was no significant difference regarding the frequency of positive results for lupus anticoagulant, anti-cardiolipin, and anti-beta-2-GP-I antibodies, between the symptomatic and asymptomatic group. The percentage of persons with simultaneous positivity for two or all three antiphospholipid antibodies was the same in both groups of subjects. Conclusion: As opposed to previous studies, our study did not demonstrate a correlation between the titer of antiphospholipid antibodies and the clinical manifestations of APS. Symptomatic and asymptomatic patients did not significantly differ in the frequency of elevated antibodies. These results indicate that the presence of other factors, which are as yet little-known, is necessary for the clinical manifestations of APS.","PeriodicalId":286220,"journal":{"name":"Srpski medicinski casopis Lekarske komore","volume":"07 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127292621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibiotic prophylaxis in abdominal surgery: Compliance with international guidelines 腹部手术中的抗生素预防:符合国际指南

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-35917

J. Veličković, S. Sredić, Aleksandra Radovanović-Spurnić, I. Lazic, I. Palibrk, V. Mioljević, S. Ostojić

{"title":"Antibiotic prophylaxis in abdominal surgery: Compliance with international guidelines","authors":"J. Veličković, S. Sredić, Aleksandra Radovanović-Spurnić, I. Lazic, I. Palibrk, V. Mioljević, S. Ostojić","doi":"10.5937/smclk3-35917","DOIUrl":"https://doi.org/10.5937/smclk3-35917","url":null,"abstract":"Introduction. Antibiotic prophylaxis (AP) in surgery is an important measure that contributes to the prevention of surgical site infection. International and national guidelines provide clear recommendations for the proper implementation of antibiotic prophylaxis. However, many studies indicate poor compliance in many health care centers. Aim: Our study aimed to determine the level of compliance in the application of antibiotic prophylaxis in abdominal surgery with the guidelines. Materials and methods: The retrospective study included all patients which were operated on at the Clinic for Digestive Surgery of the University Clinical Center of Serbia (UCCS), during the period January - March 2019 (270 patients). Medical records provided information about the type of surgery, the choice of antibiotic, the time of application, the route of administration, the need for redosing, the duration of antibiotic prophylaxis administration, as well as the presence of drug allergies. The collected data were analyzed by descriptive and analytical statistics (ch2 test). Results: During the study period, 270 patients were operated on at the Clinic for Digestive Surgery, of whom 227 (84.1%) received antibiotic prophylaxis. Cefazolin, an antibiotic recommended for most abdominal surgeries, was administered to only 17 (6.3%) patients. The majority of patients (64.4%) received antibiotic prophylaxis within 30 minutes of the beginning of surgery. The duration of antibiotic prophylaxis of up to 24 hours after the operation was applied in 13.1% of patients. Conclusion: Compliance with the guidelines was low, while full compliance with the recommendations for antibiotic prophylaxis was achieved only with regards to the route of antibiotic administration.","PeriodicalId":286220,"journal":{"name":"Srpski medicinski casopis Lekarske komore","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133192708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

BK polyomavirus as the cause of hemorrhagic cystitis in patients treated with allogeneic stem cell transplantation BK多瘤病毒作为异基因干细胞移植患者出血性膀胱炎的病因

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-37987

S. Stanković, Irena Đunić

{"title":"BK polyomavirus as the cause of hemorrhagic cystitis in patients treated with allogeneic stem cell transplantation","authors":"S. Stanković, Irena Đunić","doi":"10.5937/smclk3-37987","DOIUrl":"https://doi.org/10.5937/smclk3-37987","url":null,"abstract":"Introduction: BK polyomavirus is a double-stranded DNA virus from the Polyomaviridae family. According to DNA sequences, this virus can be classified into six genotypes. In hematological patients enrolled in allogeneic hematopoietic stem cell transplantation (HSCT) programs, it can lead to hemorrhagic cystitis. Aim: The aim of this study is calculating the prevalence of BK polyomavirus PCR (polymerase chain reaction) positivity in the blood and urine of patients involved in allogeneic HSCT, determining the predictive factors for clinical presentation of BK polyomavirus-associated hemorrhagic cystitis, as well as determining its effects on overall survival (OS) of the patients. Materials and methods: This retrospective cohort study enrolled 42 patients from the Clinic of Hematology of the University Clinical Center of Serbia. The presence of the virus in blood and urine was determined by the PCR method. The survival rate of the patients in relation to hemorrhagic cystitis was calculated with the Kaplan-Meier method and comparison was performed with the log-rank test. Results: A positive PCR result in the blood was found in 97.6% of the subjects, while urine tested positive in 100% of patients. The estimated survival time in patients without hemorrhagic cystitis was 44.357 months, while the group with the clinical presentation of hemorrhagic cystitis had an estimated survival time of 17.395 months. Based on the log-rank test, we found a significant difference in survival between those groups of patients (p = 0.049). With regards to leukocyte engraftment day, patients engrafted after D+14, had a higher frequency of hemorrhagic cystitis (p = 0.037). Conclusion: BK polyomavirus-associated hemorrhagic cystitis is a common complication of treatment in patients suffering from hematological malignancies who are enrolled in an alo-HSCT program, and has a significant impact on OS..","PeriodicalId":286220,"journal":{"name":"Srpski medicinski casopis Lekarske komore","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114531499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thrombotic microangiopathy as the first manifestation of disseminated malignant disease 血栓性微血管病变是播散性恶性疾病的首要表现

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-40946

Ž. Todorovic, Marko Anđelić

引用次数: 0

Radiological finding of pneumomediastinum as a rare complication of emphysematous pyelonephritis 肺气肿性肾盂肾炎罕见并发症纵隔气肿的影像学表现

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-35705

K. Mijović, Nevena Stanišić, D. Mašulović, D. Šaponjski, N. Bogosavljevic, Dragan Vasin, Milica Mitrovic-Jovanovic

{"title":"Radiological finding of pneumomediastinum as a rare complication of emphysematous pyelonephritis","authors":"K. Mijović, Nevena Stanišić, D. Mašulović, D. Šaponjski, N. Bogosavljevic, Dragan Vasin, Milica Mitrovic-Jovanovic","doi":"10.5937/smclk3-35705","DOIUrl":"https://doi.org/10.5937/smclk3-35705","url":null,"abstract":"Introduction: Emphysematous pyelonephritis is a rare, acute, and life-threatening necrotizing renal infection caused by gas-producing facultative anaerobes, such as Escherichia coli, Klebsiella, and Proteus, most commonly in the setting of underlying diabetes mellitus. Pneumomediastinum is a rare imaging finding in this disease, and a high index of suspicion is required for diagnosing emphysematous pyelonephritis in patients presenting with pneumomediastinum, in the right clinical setting. Case presentation: We present the case of a middle-aged female patient with symptoms and laboratory findings indicating infection, renal failure, and hyperglycemia, and a personal history of diabetes mellitus. The imaging procedures revealed findings of a severe and advanced necrotizing renal infection with parenchymal destruction and intraparenchymal gas collections extending into the perirenal and pararenal spaces. We established the diagnosis of emphysematous pyelonephritis accompanied by perirenal abscess formation and pneumoretroperitoneum, with gas collections propagating into the mediastinum. In the setting of such a severe form of infection, the patient underwent immediate surgery with left nephrectomy. Despite prompt and intensive treatment, the patient unfortunately succumbed to the disease during the postoperative period. Conclusion: Pneumomediastinum is a rare complication of retroperitoneal processes, and, when present, indicates their extensiveness, often being an ominous prognostic sign. By presenting this case, we aim to highlight the severity of this form of renal infection and the unequivocal need for immediate response, as well as to emphasize the significance of imaging findings, which are somewhat unusual, but should raise suspicion of an insidious and serious retroperitoneal infection.","PeriodicalId":286220,"journal":{"name":"Srpski medicinski casopis Lekarske komore","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122518110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The prospects of improving dental health care management: A case study by the "Vukadinovic" dental practice, the Republic of Serbia 改善牙科保健管理的前景:塞尔维亚共和国"Vukadinovic"牙科诊所的案例研究

Srpski medicinski casopis Lekarske komore Pub Date : 1900-01-01 DOI: 10.5937/smclk3-40962

A. Vukadinović

{"title":"The prospects of improving dental health care management: A case study by the \"Vukadinovic\" dental practice, the Republic of Serbia","authors":"A. Vukadinović","doi":"10.5937/smclk3-40962","DOIUrl":"https://doi.org/10.5937/smclk3-40962","url":null,"abstract":"Introduction: Dental medicine is a part of health care which is responsible for providing dental health care for the population of an area using all available means - by preserving, improving and establishing the specific functions and the appearance of the oral cavity and its individual parts, by studying and preventing common diseases of the mouth, as well as by treating diseases, disorders and mouth and dental injuries. The system of dental health care in the Republic of Serbia requires changes in the field of legislation and the organizational process, as well as financial investments for the purpose of improving the organizational process and achieving a greater number of professional staff that would provide dental services. The McKinsey 7S Model is a good tool for checking the managing abilities and the capacity of a certain organization to respond to the modern demands of its users. Aim: The aim of the paper was to investigate the prospects of improving the current dental health care management system. Methods: The method involves a case study on applying the McKinsey 7S diagnostic model to a private dental practice. Results: The results of the research served as the basis for proposing potential improvements to dental health care management.","PeriodicalId":286220,"journal":{"name":"Srpski medicinski casopis Lekarske komore","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116065777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0