A. Balamurugan, S. Teo, Jianxi Yang, Zhongbo Peng, Xulei Yang, Zeng Zeng
{"title":"ResHNet: Spectrograms Based Efficient Heart Sounds Classification Using Stacked Residual Networks","authors":"A. Balamurugan, S. Teo, Jianxi Yang, Zhongbo Peng, Xulei Yang, Zeng Zeng","doi":"10.1109/BHI.2019.8834578","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834578","url":null,"abstract":"Cardiovascular disease (CVD) is one of the major contributors of global mortality rate as it accounts for almost 31% of the worldwide deaths. As per World Health Organization (WHO), CVD continues to be the number one cause of death in the world. In some parts of the world, access to expert doctors and diagnosis are difficult. Thus an efficient and quick diagnosis of heart disease method is needed especially for low-income and middle-income countries where Magnetic Resonance Imaging (MRI) and Ultrasound becomes a constraint in terms of the resources to save human life. With the tremendous technology advancement in the medical field, deep learning has gained more attention to automate most of the initial diagnosis of diseases. This fosters continuous research in adopting deep learning methods for automatic classification of heart sounds to identify any abnormalities. In this work, we aim to investigate the efficiency of introducing residual modules in heart sounds classification using a deep neural network. This approach involves the following steps: (i) Generation of Spectrograms for every 1D audio signal using Spectrogram generator module (ii) Training of residual network based classifier for identifying normal and abnormal heart sounds based on the Spectrograms. The standard dataset given for 2016 PhysioNet/CinC Challenge has been used here for validating our residual network. This method achieved around 97% accuracy on the independent hidden test set performing best without incorporating any segmentation or additional Mel-Frequency Cepstrum Coefficients (MFCC) features of the audio signals and just the learned features from the image-based representations. Various baseline results of other deep learning based approaches have also been considered for evaluating the robustness of this framework.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123296229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ruhan Yi, Moein Enayati, J. Keller, M. Popescu, M. Skubic
{"title":"Non-Invasive In-Home Sleep Stage Classification Using a Ballistocardiography Bed Sensor","authors":"Ruhan Yi, Moein Enayati, J. Keller, M. Popescu, M. Skubic","doi":"10.1109/BHI.2019.8834535","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834535","url":null,"abstract":"Longitudinal monitoring of sleep related parameters can be used for early detection of diseases and also as an indication to physicians for effective adjustment of medication and dosage treatments for people at risk. The correlation between sleep disorders and health conditions such as Alzheimer's and Parkinson's diseases has already been reported in the literature. In this paper, we propose the use of a hydraulic bed sensor for sleep stage classification. Our main motivation of using the bed sensor is to provide a non-invasive, in-home monitoring system, which tracks the changes in health conditions of the subjects over time. Regular polysomnography data from a Sleep Lab have been used as the ground truth, with the focus on three sleep stages, namely, awake, rapid eye movement (REM) and non-REM sleep (NREM). A total of 74 features including heart rate variability (HRV) features, respiratory rate variability (RV) features, and linear frequency cepstral coefficients (LFCC) were extracted from the bed sensor data. Support Vector Machines (SVM) and K-Nearest Neighbors (KNN) classification methods were applied to these features. Our results show accuracy as good as 85% with 0.74 kappa, in the detection of these three sleep stages. These results show promise in the ability of the bed sensor to monitor and track sleep quality and sleep related disorders noninvasively.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126418706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatemeh Fahimi, Zhuo Zhang, Wooi-Boon Goh, K. Ang, Cuntai Guan
{"title":"Towards EEG Generation Using GANs for BCI Applications","authors":"Fatemeh Fahimi, Zhuo Zhang, Wooi-Boon Goh, K. Ang, Cuntai Guan","doi":"10.1109/BHI.2019.8834503","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834503","url":null,"abstract":"Brain-computer interface has been always facing serious data-related problems such as lack of the sufficient data and data corruption. Artificial data generation is a potential solution to address these issues. Among generative techniques, the method of generative adversarial networks (GANs) with the successful applications in image processing has gained a lot of attention. The application of GANs for time-series data generation is a recent growing topic that first of all its feasibility needs to be assessed. In the present study, we investigate the performance of GANs in generating artificial electroencephalogram (EEG) signals. The results suggest that the generated EEG signals by GANs resemble the temporal, spectral, and spatial characteristics of real EEG. It thus opens new perspectives for further research in this area.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114147336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Leveraging transfer learning techniques for classifying infant vocalizations","authors":"Aditya Gujral, Kexin Feng, Gulshan Mandhyan, Nfn Snehil, Theodora Chaspari","doi":"10.1109/BHI.2019.8834666","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834666","url":null,"abstract":"Infant vocalizations serve various communicative functions and are related to several developmental factors. Different types of vocalizations depict distinct spectro-temporal patterns, which can be recovered and learned using emerging end-to-end machine learning systems. A common problem in such systems is the limited availability of labelled data preventing reliable training. Transfer learning can be used to mitigate this problem by taking advantage of additional data resources relevant to the problem of interest. We propose a transfer learning framework which relies on neural network fine-tuning, and explore various types of architectures, such as a convolutional neural network (CNN) and long-term-short-memory (LSTM) recurrent neural networks with and without an attention mechanism. Our target data come from the Cry Recognition In Early Development (CRIED), while the source data come from three publicly available resources: the Oxford Vocal (OxVoc) Sounds database, the Google AudioSet, and the Freesound repository. Our results indicate that the neural network architectures trained with the proposed transfer learning approach outperform the corresponding networks solely trained on the target data, as well as neural networks pre-trained on large-scale image datasets and adapted to the target data (e.g., VGG16). These suggest the effectiveness of adaptation techniques combined with appropriate publicly available datasets for mitigating the limited availability of labelled data in human-related applications.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"111 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117193967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utilizing Consumer-grade Wearable Sensors for Unobtrusive Rehabilitation Outcome Prediction","authors":"Jason Conci, Gina Sprint, D. Cook, D. Weeks","doi":"10.1109/BHI.2019.8834512","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834512","url":null,"abstract":"Rehabilitation outcome prediction can be useful for clinicians providing therapy services to patients undergoing inpatient medical rehabilitation. Machine learning models trained with medical record information available at admission can predict rehabilitation outcomes fairly well. In our previous work, we found rehabilitation outcome prediction accuracy can be improved by also including inertial sensor-based features that objectively quantify patient movement abilities during therapy tasks. In this paper, we extend our prior work by unobtrusively and continuously collecting minute-by-minute movement data from 15 patients throughout their stay of inpatient rehabilitation using inexpensive, consumer-grade fitness trackers, specifically the Fitbit Charge with heart rate. From the Fitbit time series data, we extract features related to physical activity, heart rate, and sleep quality. We use these features as inputs to machine learning models to predict the discharge Functional Independence Measure (FIM) rehabilitation outcome. We also utilize patient similarity techniques to improve prediction accuracy. Results indicate prediction accuracy with the consumer-grade sensor data is close to the same accuracy as prior work using research-grade inertial sensor data. Using consumer-grade fitness devices to obtain highly accurate FIM predictions can help clinicians plan therapy activities during the inpatient stay, as well as assist with discharge to an appropriate setting.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"146 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115738894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outside the Hospital Walls: Associations of Value Based Care Metrics and Community Health Factors","authors":"C. Markley, K. Feldman, N. Chawla","doi":"10.1109/BHI.2019.8834487","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834487","url":null,"abstract":"As the healthcare industry shifts from traditional fee-for-service payment to value-based care models, the need to accurately quantify and compare the performance of institutions has become an integral component of both policy and research. To date, several notable metrics have been introduced, including the Centers for Medicare and Medicaids Hospital Value Based Purchasing (HVBP) program. However, despite widespread adoption, these standards suffer from a fundamental oversight. Where the factors utilized to characterize performance reflect only intrinsic facets of an institutions care, capturing elements of mortality rates, patient satisfaction, outcomes, and spending. Yet, this approach is directly at odds with our current understanding of health and wellness, as it is well known that social, economic, and community factors are deeply intertwined with healthcare outcomes. To this end, with institutions spread across diverse geographic regions, our manuscript demonstrates that HVBP performance metrics do not exist in isolation. Rather, they possess strong associations to the community factors in which the institution resides. Aggregating a broad set of factors from disparate data sources, this work moves through the informatics pipeline. Identifying performance scoring profiles though clustering and employing robust linear models to uncover novel relationships and advance the discussion around the need for value-based care quality metrics.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"223 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122502007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Liss Hernández, Laura Lopez-Perez, Ana M. Ugena, M. Arredondo, G. Fico
{"title":"Designing an ontology for Head and Neck Cancer research","authors":"Liss Hernández, Laura Lopez-Perez, Ana M. Ugena, M. Arredondo, G. Fico","doi":"10.1109/BHI.2019.8834473","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834473","url":null,"abstract":"Head and Neck Cancer (HNC) is one of the cancers with the highest mortality and recurrence rates. Nowadays, HNC research is focused on enhancing the prognostic and quality of life of patients. This disease involves heterogeneous and multiscale data that should be integrated and analyzed during the process of diagnosis, prognosis and treatment of HNC. In this work, we propose a solution capable of integrating all this data, providing a standardized vocabulary of terms involved during the HNC research process. The solution is based on the creation of the first ontology that models the HNC disease and collects and organize hierarchically, not only the data at patient level, but also population data and concepts related to clinical and scientific literature.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115019060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jonathan S. Zia, Jacob P. Kimball, M. Shandhi, O. Inan
{"title":"Automated Identification of Persistent Time-Domain Features in Seismocardiogram Signals","authors":"Jonathan S. Zia, Jacob P. Kimball, M. Shandhi, O. Inan","doi":"10.1109/BHI.2019.8834555","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834555","url":null,"abstract":"In the field of cardiac monitoring, the seismocardiogram (SCG) measures the movement of the chest wall using accelerometers and gyroscopes. A key limitation of SCG signals is their sensitivity to transient signal disruptions primarily due to motion artifacts. This work describes a method for automated extraction of time-domain features in SCG signals in the presence of such artifacts, using an iterative method of clustering and re-sampling features to optimize consistency. The accelerometer (axl) and gyroscope (gyr) features extracted with this method are shown to correlate more strongly (median $R^{2}=0.88 (mathbf{axl}), 0.88 (mathbf{gyr})$) with the reference standard for pre-ejection period (PEP), impedance cardiography (ICG), than both peak-counting $(R^{2}=0.29 (mathbf{axl}), 0.48 (mathbf{gyr}))$ and manual labeling $(R^{2}=0.44 (mathbf{axl}), 0.38 (mathbf{gyr}))$ in the post-exercise period. This result has implications for the feasibility of at-home SCG monitoring.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129716281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhiguo Zhou, M. Dohopolski, Liyuan Chen, Xi Chen, Steve B. Jiang, D. Sher, Jing Wang
{"title":"Reliable lymph node metastasis prediction in head & neck cancer through automated multi-objective model","authors":"Zhiguo Zhou, M. Dohopolski, Liyuan Chen, Xi Chen, Steve B. Jiang, D. Sher, Jing Wang","doi":"10.1109/BHI.2019.8834658","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834658","url":null,"abstract":"Lymph node metastasis (LNM) plays an important role for accurately diagnosing and treating the patients with head & neck cancer. Positron emission tomography (PET) and computed tomography (CT) are two primary imaging modalities used for identifying LNM status. However, the uncertainty of LNM may exist especially for reactive or small nodes. Furthermore, identifying the LNM on PET or CT is greatly dependent on the physician's experience. Therefore, developing a reliable and automatic model is essential for accurately identifying LNM. Multi-objective models have shown promising predictive results by considering different objectives such as sensitivity and specificity. However, most multi-objective models need to choose an optimal model manually. In this work, we proposed an automated multi-objective learning model (AutoMO) for predicting LNM reliably. Instead of picking one optimal model, all the Pareto-optimal models with the calculated relative weights are used in AutoMO. Then the evidential reasoning (ER) approach is used for fusing the output probability for obtaining more reliable results than traditional fusion method. We built three models for PET, CT and PET&CT and the results showed that PET&CT outperformed two single modality based models. The comparative study demonstrated that AutoMO obtained better performance than current available multi-objective and deep learning methods, and more reliable results can be acquired when using ER fusion.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130008082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fereshteh S. Bashiri, Jonathan C. Badger, R. D'Souza, Zeyun Yu, P. Peissig
{"title":"Lung Nodule Classification Using Combined Deep and Spectral 3D Shape Features","authors":"Fereshteh S. Bashiri, Jonathan C. Badger, R. D'Souza, Zeyun Yu, P. Peissig","doi":"10.1109/BHI.2019.8834537","DOIUrl":"https://doi.org/10.1109/BHI.2019.8834537","url":null,"abstract":"Accurate diagnosis of lung nodules is essential for detection and assessment of lung cancer. The present contribution proposes a descriptive model for diagnostic classification of lung nodules by jointly using deep and spectral features from the 3D surface structure of nodules. To the best of our knowledge, this is the first work that utilizes a point cloud (PC)-based deep network for extracting nodule shape features. The PC-based deep network takes into account the 3D context of a nodule; meanwhile, it is extensively less computationally intensive. The spectral features prevent over-fitting, a common problem of deep networks trained by relatively small dataset in the medical imaging domain, and compensates for missing information of mesh connections. Experimental results reveal that our descriptive model demonstrates high sensitivity (87.23%) as well as high specificity (89.80%) with a total accuracy of 88.54% for reliable and accurate prediction of lung nodule malignancy.","PeriodicalId":281971,"journal":{"name":"2019 IEEE EMBS International Conference on Biomedical & Health Informatics (BHI)","volume":"183 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134505758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}