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Peculiarities of the ultrastructure of neurons of the neocortex of 5-day-day rats under conditions of prenatal alcoholization 产前酒精化条件下5日龄大鼠新皮层神经元超微结构的特点
Journal of Chronomedicine Pub Date : 2021-07-14 DOI: 10.36361/2307-4698-2020-23-1-35-38
L. Bon, S. Zimatkin
{"title":"Peculiarities of the ultrastructure of neurons of the neocortex of 5-day-day rats under conditions of prenatal alcoholization","authors":"L. Bon, S. Zimatkin","doi":"10.36361/2307-4698-2020-23-1-35-38","DOIUrl":"https://doi.org/10.36361/2307-4698-2020-23-1-35-38","url":null,"abstract":"The aim of this work was to study the ultrastructure of the internal pyramidal neurons of the neocortex of 5-day-old rat pups after antenatal alcoholization. The studies were carried out on female outbred white rats with an initial weight of 230 ± 20 g and their offspring. Prenatal alcoholization causes deep and varied ultrastructural changes in pyramidal neurons in the neocortex of 5-day-old rats. Moreover, these violations of direct action not only as a consequence of the damaging effect of alcohol, its metabolite acetehyde or the oxidative stress they cause on the membranes and organelles of neurons during embryogenesis, but also as a violation of the normal \"program\" of development\" of neurons in the cortex.","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"229 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134109016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of the rat isocortex in antenatal and postnatal ontogenesis 大鼠同皮层在产前和产后发育中的发育
Journal of Chronomedicine Pub Date : 2021-07-14 DOI: 10.36361/2307-4698-2020-23-1-31-34
E. Bon'
{"title":"Development of the rat isocortex in antenatal and postnatal ontogenesis","authors":"E. Bon'","doi":"10.36361/2307-4698-2020-23-1-31-34","DOIUrl":"https://doi.org/10.36361/2307-4698-2020-23-1-31-34","url":null,"abstract":"This paper analyses and summarizes the literature data on the development of the rat isocortex in antenatal and postnatal ontogenesis. Information about the maturation periods of the isocortex neurons provides a fundamental basis for further studies of its development and the influence of various endogenous and exogenous factors on this process.","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114583314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sleep and Covid-19: neurophysiological and biochemical issues 睡眠和Covid-19:神经生理和生化问题
Journal of Chronomedicine Pub Date : 2021-07-14 DOI: 10.36361/2307-4698-2020-23-1-22-30
Y. Boldyreva
{"title":"Sleep and Covid-19: neurophysiological and biochemical issues","authors":"Y. Boldyreva","doi":"10.36361/2307-4698-2020-23-1-22-30","DOIUrl":"https://doi.org/10.36361/2307-4698-2020-23-1-22-30","url":null,"abstract":"Functional disorders of the nervous system against the background of Covid-19 are reviewed with the emphasis on sleep and circadian clock disorders during the pandemic. The pandemic is regarded as the strong stress factor that affects sleep and the clock. A large risk group consists of elderly people and people with concomitant somatic pathology. Data on the effect of SARS-CoV-2 on other organs and systems, on the functioning of the immune system, are presented.","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115406391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian clock precision, health, and longevity 生物钟精确，健康长寿
Journal of Chronomedicine Pub Date : 2021-07-14 DOI: 10.36361/2307-4698-2020-23-1-3-15
D. Gubin, S. Kolomeichuk, D. Weinert
{"title":"Circadian clock precision, health, and longevity","authors":"D. Gubin, S. Kolomeichuk, D. Weinert","doi":"10.36361/2307-4698-2020-23-1-3-15","DOIUrl":"https://doi.org/10.36361/2307-4698-2020-23-1-3-15","url":null,"abstract":"An accurate circadian clock, associated with the precise intrinsic period, tau, can be linked with a definite chronotype and health status. Exemplified by different animal species, and, as we argue herein, may as well be in humans, endogenous tau close enough to 24 hours is associated with higher life expectancy, lower morbidity, and is possibly adhered to moderate morning chronotype. Accurate circadian tau facilitates maintaining a high amplitude of circadian rhythms, a phenotypic trait that is related to health and longevity. Some genetic factors that coordinate tau and ensure circadian clock precision is considered.","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114292515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
The effect of the intestinal microbiota and its metabolites on the central and peripheral circadian clock 肠道菌群及其代谢物对中枢和外周生物钟的影响
Journal of Chronomedicine Pub Date : 2021-07-14 DOI: 10.36361/2307-4698-2020-23-1-16-21
I. V. Pisarev, V. V. Varnitsyna
{"title":"The effect of the intestinal microbiota and its metabolites on the central and peripheral circadian clock","authors":"I. V. Pisarev, V. V. Varnitsyna","doi":"10.36361/2307-4698-2020-23-1-16-21","DOIUrl":"https://doi.org/10.36361/2307-4698-2020-23-1-16-21","url":null,"abstract":"The article describes the factors affecting the intestinal microbiota, which, in turn, lead to changes in the central and peripheral circadian clocks of the host. The role of the diet and the sleep-wake cycle on the intestinal microbiota, the relationship of nutrition and microbiota on gene expression are discussed, and the influence of microbial metabolites, short-chain fatty acids on the expression of clock genes are considered.","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129066119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
GENETIC BASES OF THE RAT BRAIN EMBRYONIC DEVELOPMENT 大鼠脑胚胎发育的遗传基础
Journal of Chronomedicine Pub Date : 1900-01-01 DOI: 10.36361/2307-4698-2019-21-2-28-31
E. Bon'
{"title":"GENETIC BASES OF THE RAT BRAIN EMBRYONIC DEVELOPMENT","authors":"E. Bon'","doi":"10.36361/2307-4698-2019-21-2-28-31","DOIUrl":"https://doi.org/10.36361/2307-4698-2019-21-2-28-31","url":null,"abstract":"","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129589687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian regulation of adverse cardiovascular events 不良心血管事件的昼夜节律调节
Journal of Chronomedicine Pub Date : 1900-01-01 DOI: 10.36361/23074698_2022-24_1_3
S. B. Tsiryateva, S. A. Pylenko, L. A. Arutyunyan
{"title":"Circadian regulation of adverse cardiovascular events","authors":"S. B. Tsiryateva, S. A. Pylenko, L. A. Arutyunyan","doi":"10.36361/23074698_2022-24_1_3","DOIUrl":"https://doi.org/10.36361/23074698_2022-24_1_3","url":null,"abstract":"","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131786288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CIRCADIAN CLOCK PRECISION, CHRONOTYPE, HEALTH AND LONGEVITY 生物钟精确，时间类型，健康和长寿
Journal of Chronomedicine Pub Date : 1900-01-01 DOI: 10.36361/2307-4698-2019-21-2-14-27
D. Gubin, S. Kolomeichuk
{"title":"CIRCADIAN CLOCK PRECISION, CHRONOTYPE, HEALTH AND LONGEVITY","authors":"D. Gubin, S. Kolomeichuk","doi":"10.36361/2307-4698-2019-21-2-14-27","DOIUrl":"https://doi.org/10.36361/2307-4698-2019-21-2-14-27","url":null,"abstract":"","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134633108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Chronobiology of icu mortality. Controllable and uncontrollable factors icu死亡率的时间生物学研究。可控与不可控因素
Journal of Chronomedicine Pub Date : 1900-01-01 DOI: 10.36361/23074698_2022-24_1_6
N. Shen, A. S. Minin
{"title":"Chronobiology of icu mortality. Controllable and uncontrollable factors","authors":"N. Shen, A. S. Minin","doi":"10.36361/23074698_2022-24_1_6","DOIUrl":"https://doi.org/10.36361/23074698_2022-24_1_6","url":null,"abstract":"","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122714272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Circadian rhythms in intensive care unit patients: from cell to person 重症监护病房病人的昼夜节律:从细胞到人
Journal of Chronomedicine Pub Date : 1900-01-01 DOI: 10.36361/23074698_2022-24_1_10
N. Shen, S. B. Tsiryatyeva, S. Mukhacheva, V. V. Logvinenko
{"title":"Circadian rhythms in intensive care unit patients: from cell to person","authors":"N. Shen, S. B. Tsiryatyeva, S. Mukhacheva, V. V. Logvinenko","doi":"10.36361/23074698_2022-24_1_10","DOIUrl":"https://doi.org/10.36361/23074698_2022-24_1_10","url":null,"abstract":"","PeriodicalId":277268,"journal":{"name":"Journal of Chronomedicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127803210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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