生物钟精确,健康长寿

D. Gubin, S. Kolomeichuk, D. Weinert
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引用次数: 1

摘要

一个精确的生物钟,与精确的内在周期相关联,可以与明确的时间类型和健康状况联系起来。在不同的动物物种中,正如我们在本文中所论证的,可能在人类中也是如此,内源性tau足够接近24小时与较高的预期寿命、较低的发病率相关,并且可能与适度的早晨睡眠类型有关。准确的昼夜节律tau有助于维持昼夜节律的高振幅,这是一种与健康和长寿相关的表型特征。一些遗传因素,协调tau和确保生物钟精度被考虑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Circadian clock precision, health, and longevity
An accurate circadian clock, associated with the precise intrinsic period, tau, can be linked with a definite chronotype and health status. Exemplified by different animal species, and, as we argue herein, may as well be in humans, endogenous tau close enough to 24 hours is associated with higher life expectancy, lower morbidity, and is possibly adhered to moderate morning chronotype. Accurate circadian tau facilitates maintaining a high amplitude of circadian rhythms, a phenotypic trait that is related to health and longevity. Some genetic factors that coordinate tau and ensure circadian clock precision is considered.
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