The effect of the intestinal microbiota and its metabolites on the central and peripheral circadian clock

Abstract

The article describes the factors affecting the intestinal microbiota, which, in turn, lead to changes in the central and peripheral circadian clocks of the host. The role of the diet and the sleep-wake cycle on the intestinal microbiota, the relationship of nutrition and microbiota on gene expression are discussed, and the influence of microbial metabolites, short-chain fatty acids on the expression of clock genes are considered.