Chemical Data Collections最新文献_第2页

Synthesis and Biological Evaluation of chalcone derivatives of [1,2,4]triazolo[4,3-a]pyridines as Anticancer Agents 抗癌药物[1,2,4]三唑[4,3-a]吡啶查尔酮衍生物的合成及生物学评价

IF 2.7

Chemical Data Collections Pub Date : 2026-03-01 Epub Date: 2026-02-02 DOI: 10.1016/j.cdc.2026.101229

Nagi Reddy. K , Jyothi Mandala , Somaiah Nalla

{"title":"Synthesis and Biological Evaluation of chalcone derivatives of [1,2,4]triazolo[4,3-a]pyridines as Anticancer Agents","authors":"Nagi Reddy. K , Jyothi Mandala , Somaiah Nalla","doi":"10.1016/j.cdc.2026.101229","DOIUrl":"10.1016/j.cdc.2026.101229","url":null,"abstract":"<div><div>A new series of chalcone derivatives of [1,2,4]triazolo[4,3-a]pyridines (<strong>13a-j) were synthesized by the reaction between 2-(5-(8-(pyridin-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)pyrimidin-2-yl)oxazole-5-carbaldehyde (11) intermediate and different types of aromatic ketones (12a-j) in the presence of piperidine in ethanol at reflux for 12 hrs time period. Further, these are screened against four human cancer cell lines such as human breast cancer cell line (MCF-7), human lung cancer cell line (A549), human colon cancer cell line (Colo-205) and human ovarian cancer cell line (A2780) by employing the MTT assay. The results are compared with etoposide as used as positive control. According the results most of the tested compounds showed good to moderate activity than positive control. The IC50 values ranges of compounds from 0.12±0.071 µM to 6.36±1.97 µM, as well as etoposide showed values ranges from 0.17</strong> ± 0.034 µM to 3.34 ± 0.152 µM, respectively. Amongst, four compounds <strong>13a, 13b, 13i</strong> & <strong>13j</strong> exhibited remarkable activity than positive control. Specifically, the compound <strong>13j</strong> with 3,5-dinitro electron withdrawing substituent on the phenyl ring displayed most promising activity against MCF-7, A549, Colo-205 and A2780 cell lines with IC<sub>50</sub> values of 0.12±0.071 µM; 0.14±0.049 µM; 0.32±0.054 µM & 0.28±0.063 µM)</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"62 ","pages":"Article 101229"},"PeriodicalIF":2.7,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146170920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and structural analysis of novel bisallenylphosphoramide derivatives 新型双烯基磷酰胺衍生物的合成及结构分析

IF 2.7

Chemical Data Collections Pub Date : 2026-03-01 Epub Date: 2026-02-12 DOI: 10.1016/j.cdc.2026.101230

K. Abaid , C. Ben Aissa , N. Jebli , K. Van Hecke , S. Touil

引用次数: 0

Oxadiazole-thiadiazole hybrid analogues as potential anti-diabetic and anti-Alzheimer’s agents: synthesis, in vitro biological evaluation, in silico molecular docking and ADME Analysis 作为潜在抗糖尿病和抗阿尔茨海默病药物的恶二唑-噻二唑杂化类似物：合成、体外生物学评价、硅分子对接和ADME分析

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-12-18 DOI: 10.1016/j.cdc.2025.101220

Muhammad Shahid Nadeem , Sundas Tariq , Hayat Ullah , Imran Kazmi , Mustafa A. Zeyadi , Fazal Rahim , Syed Adnan Ali Shah

{"title":"Oxadiazole-thiadiazole hybrid analogues as potential anti-diabetic and anti-Alzheimer’s agents: synthesis, in vitro biological evaluation, in silico molecular docking and ADME Analysis","authors":"Muhammad Shahid Nadeem , Sundas Tariq , Hayat Ullah , Imran Kazmi , Mustafa A. Zeyadi , Fazal Rahim , Syed Adnan Ali Shah","doi":"10.1016/j.cdc.2025.101220","DOIUrl":"10.1016/j.cdc.2025.101220","url":null,"abstract":"<div><div>A new series of oxadiazole-thiadiazole hybrid analogs were synthesized, characterized by NMR, HR-EIMS and tested for acetylcholinesterase, butyrylcholinesterase, <em>α</em>-amylase and <em>α</em>-glucosidase inhibition. All analogues showed good inhibitory potentials with varying degree of cholinesterase inhibition potentials ranging in between 6.20 <strong>±</strong> 0.18 to 23.20 <strong>±</strong> 0.18 <em>µ</em>M (AChE) and 5.40 <strong>±</strong> 0.20 to 29.08 <strong>±</strong> 0.03 <em>µ</em>M (BuChE) when compared with standard drug allanzanthane having IC<sub>50</sub> values 14.11 ± 0.03 <em>µ</em>M and 16.02 ± 0.24 <em>µ</em>M, respectively. All the analogues also displayed varying range of inhibitory potentials against <em>α</em>-glucosidase and <em>α</em>-amylase with IC<sub>50</sub> values ranging between 6.02 <strong>±</strong> 0.10 to 27.40 <strong>±</strong> 0.20 (<em>α</em>-glucosidase) and 5.07 <strong>±</strong> 0.04 to 30.40 <strong>±</strong> 0.20 <em>µ</em>M (<em>α</em>-amylase) as compared to standard drug acarbose (IC<sub>50</sub> = 14.11 ± 0.03 <em>µ</em>M and 18.05 ± 0.10 <em>µ</em>M, respectively). Limited structure activity relationship were established which is mainly based on the nature and position of substituents on phenyl ring. Molecular docking study were carried out to examine binding sites interactions of most active scaffolds with both targeted enzymes and ADMET analysis were performed to study the drug likeness properties.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101220"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145880795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

GC–MS metabolomic dataset of Zingiber officinale and Zingiber cassumunar essential oils with antibacterial activity 具有抗菌活性的药用生姜和香薷精油的GC-MS代谢组学数据集

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-12-01 DOI: 10.1016/j.cdc.2025.101217

Hendri Wasito , Amelia Rizqa Fauziyah , Aprilia Nur Tasfiyati , Harris Antonius , Yuli Widyastuti , Abdi Wira Septama

{"title":"GC–MS metabolomic dataset of Zingiber officinale and Zingiber cassumunar essential oils with antibacterial activity","authors":"Hendri Wasito , Amelia Rizqa Fauziyah , Aprilia Nur Tasfiyati , Harris Antonius , Yuli Widyastuti , Abdi Wira Septama","doi":"10.1016/j.cdc.2025.101217","DOIUrl":"10.1016/j.cdc.2025.101217","url":null,"abstract":"<div><div>Antibiotic resistance poses a global health challenge, driving the search for novel antibacterial agents. Plant-derived essential oils offer promising potential due to their diverse bioactive constituents. This study investigates the essential oils of <em>Zingiber cassumunar</em> and <em>Zingiber officinale</em>, traditionally recognized for their medicinal properties. Metabolite profiling was conducted using a non-targeted gas chromatography–mass spectrometry (GC–MS) metabolomics approach combined with chemometrics, while antibacterial activity against <em>Escherichia coli, Salmonella typhi, Shigella sonnei</em>, and <em>Bacillus cereus</em> was assessed via the broth microdilution method. The synergistic effect with tetracycline was evaluated using the checkerboard assay. A total of 169 metabolites were detected, with 85 putatively annotated. <em>Z. officinale</em> oil demonstrated stronger antibacterial activity (MIC 7.8–15.6 μg/mL) and synergistic interaction with tetracycline (FICI 0.61). These findings highlight the potential of Zingiber essential oils as alternative antibacterial agents and underscore the utility of metabolomics for elucidating their bioactive profiles.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101217"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145683755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, synthesis and biological evaluation of amide derivatives of 1,3,4-oxadiazol-pyridine-pyrimidine Derivatives as Anticancer Agents 抗癌药物1,3,4-恶二唑-吡啶-嘧啶酰胺衍生物的设计、合成及生物学评价

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-12-18 DOI: 10.1016/j.cdc.2025.101218

V.Vijaya Lakshmi , Ravi Subban , Hemalatha Devi , Thangamani Arumugam , Nalla Somaiah , Laxminarayana Eppakayala

{"title":"Design, synthesis and biological evaluation of amide derivatives of 1,3,4-oxadiazol-pyridine-pyrimidine Derivatives as Anticancer Agents","authors":"V.Vijaya Lakshmi , Ravi Subban , Hemalatha Devi , Thangamani Arumugam , Nalla Somaiah , Laxminarayana Eppakayala","doi":"10.1016/j.cdc.2025.101218","DOIUrl":"10.1016/j.cdc.2025.101218","url":null,"abstract":"<div><div>A new series of amide derivatives of 1,3,4-oxadiazol-pyridine-pyrimidine (<strong>12a-j</strong>) and their structures are confirmed by <sup>1</sup>HNMR, <sup>13</sup>CNMR and mass spectral data. Further, these were screened against four human cancer cell lines including of human breast cancer cell line (MCF-7), human lung cancer cell line (A549), human colon cancer cell line (Colo-205) and human ovarian cancer cell line (A2780) by employing of MTT assay, and the obtained results were expressed with IC<sub>50</sub> µM. Most of the tested compounds were exhibited remarkable anticancer properties as compared with etoposide (Etoposide) used as positive control. The results were summarized in <strong>Table 1</strong>. According the results, the IC<sub>50</sub> values ranges of compounds from 0.12±0.042 µM to 5.79±1.02 µM, as well as etoposide (Etoposide) showed values ranges from 0.17 ± 0.034 µM to 3.34 ± 0.152 µM, respectively. Among them, five derivatives <strong>12a, 12b, 12c, 12d</strong> and <strong>12e</strong> were displayed more potent anticancer activity than etoposide (Etoposide). In which one compound <strong>12a</strong> was showed most promising activity.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101218"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145880796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and biological evaluation of aryl incorporated (pyridin-4-yl)-1,3,4-oxadiazol-2-yl)oxazolo[5,4-b]pyridine derivatives as anticancer agents 芳基结合（吡啶-4-基）-1,3,4-恶二唑-2-基)恶唑[5,4-b]吡啶衍生物抗癌剂的合成及生物学评价

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-12-14 DOI: 10.1016/j.cdc.2025.101219

Palreddy Reshma , Saikrishna Balabadra , Swapna Maarepalli

{"title":"Synthesis and biological evaluation of aryl incorporated (pyridin-4-yl)-1,3,4-oxadiazol-2-yl)oxazolo[5,4-b]pyridine derivatives as anticancer agents","authors":"Palreddy Reshma , Saikrishna Balabadra , Swapna Maarepalli","doi":"10.1016/j.cdc.2025.101219","DOIUrl":"10.1016/j.cdc.2025.101219","url":null,"abstract":"<div><div>A new library of aryl incorporated (pyridin-4-yl)-1,3,4-oxadiazol-2-yl)oxazolo[5,4-b]pyridine (<strong>9a-j</strong>) compounds are developed to explore new heterocyclic scaffolds with potential anticancer properties. The structural novelty of these hybrids arises from the strategic combination of an oxazolo[5,4-b]pyridine core with a 1,3,4-oxadiazole linker and diverse aryl moieties—an arrangement not previously investigated for anticancer applications. All synthesized compounds were thoroughly characterized by analytical and spectroscopic techniques. Further, the anticancer activity of the newly prepared compounds (<strong>9a-j</strong>) was assessed against a panel of four human cancer cell lines like human breast cancer (MCF-7), human lung cancer (A549), human colon cancer (Colo-205) & human ovarian cancer (A2780) by using of the MTT assay, and the results are compared with the known chemotherapeutic agent etoposide. All the investigated derivatives displayed moderate to good activity. Notably, compounds 9a, 9 g, 9 h, 9i, and 9j showed the most promising results, with compound 9j demonstrating exceptional potency across the tested models.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101219"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145880751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis, biological evaluation, and computational analysis of fused bis-thiadiazole analogues as potential anti-Alzheimer’s and antidiabetic agents 作为潜在抗阿尔茨海默病和抗糖尿病药物的融合双噻二唑类似物的合成、生物学评价和计算分析

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-11-26 DOI: 10.1016/j.cdc.2025.101215

Muhammad Shahid Nadeem , Sundas Tariq , Jalaluddin Azam Khan , Shakoor Ahmad , Hayat Ullah , Gaurav Gupta , Misbah Ullah Khan , Fazal Rahim , Khushi Muhammad

{"title":"Synthesis, biological evaluation, and computational analysis of fused bis-thiadiazole analogues as potential anti-Alzheimer’s and antidiabetic agents","authors":"Muhammad Shahid Nadeem , Sundas Tariq , Jalaluddin Azam Khan , Shakoor Ahmad , Hayat Ullah , Gaurav Gupta , Misbah Ullah Khan , Fazal Rahim , Khushi Muhammad","doi":"10.1016/j.cdc.2025.101215","DOIUrl":"10.1016/j.cdc.2025.101215","url":null,"abstract":"<div><div>Fused <em>bis</em>-thiadiazole analogues (<strong>1–20</strong>) was synthesized, characterized through <sup>1</sup>HNMR, <sup>13</sup>CNMR and HR-EIMS and evaluated against acetylcholinesterase, butyrylcholinesterase, α-glucosidase and α-amylase enzymes. All compounds demonstrated inhibitory activity against AChE and BuChE, with IC₅₀ values ranging from 4.20 to 27.05 µM and 6.40 to 32.08 µM, respectively as compared to reference drug Allanzanthane (IC₅₀ = 14.11 and 16.02 µM, respectively). In a similar manner, significant inhibition was observed against α-glucosidase and α-amylase, with IC₅₀ values ranging from 3.30 to 29.20 µM and 7.07 to 32.40 µM, respectively as compared to standard drug acarbose (IC₅₀ = 14.11 and 18.05 µM). Analogues <strong>8</strong> and <strong>12</strong> emerged as most effective inhibitors of AChE and BuChE, while analogues <strong>1</strong> and <strong>5</strong> exhibited the highest activity against α-glucosidase and α-amylase enzymes. Molecular docking was conducted, revealing strong binding affinities and favourable interactions of most active derivatives within active sites of their respective target enzymes.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101215"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145735171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, synthesis, computational evaluation and kinetic study of benzofuran-derived thiazolotriazole derivatives as potential anti-urease agents 苯并呋喃衍生噻唑三唑类抗脲酶药物的设计、合成、计算评价及动力学研究

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-11-27 DOI: 10.1016/j.cdc.2025.101216

Shawkat Hayat , Hayat Ullah , Fazal Rahim , Muhammad Haroon Hamed , Amina Qureshi , Shakoor Ahmad , Misbah Ullah Khan , Muhammad Sajid , Naveed Iqbal , Mahmoud A. Abdelaziz

{"title":"Design, synthesis, computational evaluation and kinetic study of benzofuran-derived thiazolotriazole derivatives as potential anti-urease agents","authors":"Shawkat Hayat , Hayat Ullah , Fazal Rahim , Muhammad Haroon Hamed , Amina Qureshi , Shakoor Ahmad , Misbah Ullah Khan , Muhammad Sajid , Naveed Iqbal , Mahmoud A. Abdelaziz","doi":"10.1016/j.cdc.2025.101216","DOIUrl":"10.1016/j.cdc.2025.101216","url":null,"abstract":"<div><div>We synthesised a series of benzofuran-derived thiazole-triazole-fused derivatives, characterized through different techniques such as <sup>1</sup>HNMR, <sup>13</sup>CNMR and HR-EIMS and evaluated against urease enzyme. All analogues showed good inhibitory potential, having IC<sub>50</sub> values that ranged from 1.10 to 17.90 µM as compared to the reference drug thiourea (IC<sub>50</sub> = 21.86 µM). Analogues <strong>1, 2, 3, 5, 6</strong> and <strong>13</strong> (IC<sub>50</sub> = 4.20, 3.30, 1.10, 1.40, 1.40 and 2.60 µM, respectively) showed many folds greater urease inhibitory potential than the reference drug thiourea. Structure-activity relationship was established by examining the various substitution types and patterns on the phenyl ring. Molecular modelling studies of the most potent inhibitors in the urease active site suggested multiple binding interactions with different amino acid residues. DFT, ADME and kinetic analysis was also carried out, which clearly indicated that all compounds are potent urease inhibitors and can be potential lead compounds in drug designing.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101216"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145735170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Crystal structure, Hirshfeld surface analysis and antioxidant activity of a thiocyanato-incorporated copper(II) chelate based on a tridentate N2O donor Schiff base 基于三齿N2O施主席夫碱的硫氰酸铜螯合物的晶体结构、Hirshfeld表面分析和抗氧化活性

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-12-26 DOI: 10.1016/j.cdc.2025.101221

Roji J. Kunnath , Jinsa Mary Jacob , E. Manoj , M. Sithambaresan , Keerthana Narayanan , Rakesh K․E․ , Tony Francis , M.R.Prathapachandra Kurup

{"title":"Crystal structure, Hirshfeld surface analysis and antioxidant activity of a thiocyanato-incorporated copper(II) chelate based on a tridentate N2O donor Schiff base","authors":"Roji J. Kunnath , Jinsa Mary Jacob , E. Manoj , M. Sithambaresan , Keerthana Narayanan , Rakesh K․E․ , Tony Francis , M.R.Prathapachandra Kurup","doi":"10.1016/j.cdc.2025.101221","DOIUrl":"10.1016/j.cdc.2025.101221","url":null,"abstract":"<div><div>The present study explores the synthesis, characterization and detailed analysis of a copper(II) chelate [Cu(bsde)NCS], derived from the in-situ condensation of 3,5-dibromosalicylaldehyde and N,N-dimethylethylenediamine, incorporating a pseudohalide, thiocyanate (NCS<sup>-</sup>). The characterization techniques combined single crystal X-ray diffraction, electronic, FT-IR and EPR spectroscopy. SCXRD analysis reveals that the complex crystallized in the monoclinic space group <em>P</em>2<sub>1</sub>/n, with a slightly distorted square planar geometry around the copper(II). The EPR spectroscopy revealed an axial spectrum with g<sub>||</sub> > <em>g</em><sub>⊥</sub>, suggesting a distorted square planar geometry. Further insights into crystal packing and intermolecular interactions were gained through Hirshfeld surface analysis. In addition, the antioxidant activity of the complex using the DPPH radical scavenging assay, revealed promising free radical quenching efficiency.</div></div>","PeriodicalId":269,"journal":{"name":"Chemical Data Collections","volume":"61 ","pages":"Article 101221"},"PeriodicalIF":2.7,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145921315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Design, synthesis and anticancer activity of chalcone derivatives of pyrazolo[1,5-a]pyridine-1,3,4-oxadiazole 吡唑[1,5-a]吡啶-1,3,4-恶二唑查尔酮衍生物的设计、合成及其抗癌活性

IF 2.7

Chemical Data Collections Pub Date : 2026-02-01 Epub Date: 2025-11-25 DOI: 10.1016/j.cdc.2025.101214

Krishna Babu Alapati , Dasari Sravani , B.B.V. Sailaja , B. Saritha , Somaiah Nalla

引用次数: 0