{"title":"Characterization of the mechanosensitivity of tactile receptors using multivariate logistical regression","authors":"S. Bradshaw, F. Looft, S. Kohles, P. Grigg","doi":"10.1109/NEBC.2001.924722","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924722","url":null,"abstract":"The authors' initial objective was to establish a framework for modeling afferent mechanoreceptor behavior under dynamic compressive loads using multivariate regression techniques. A multivariate logistical model of the system was chosen because the system contains continuous input variables and a singular binary output variable corresponding to an \"all-or-nothing\" nerve action potential. Subsequently, this method was used to quantitatively assess the sensitivity of rapidly adapting afferents in rat hairy skin to the stimulus metrics stress, strain, and their time derivatives. In-vitro experiments involving compressive stimulation of isolated afferents using pseudorandom and non-repeating noise sequences were completed and an analysis of the data was performed using multivariate logistical regression.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"50 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129060692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The design of a 1.75-D 1280-channel ultrasound imaging system","authors":"P. Guo, Shikui Yan, Quing Zhu","doi":"10.1109/NEBC.2001.924714","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924714","url":null,"abstract":"The authors have designed a 1.75-D 1280-channel ultrasound imaging system to replace their existing 2-D 64 channel ultrasound imaging system which is used in a combined ultrasound and near infrared (NIR) diffusive light imager for breast cancer imaging. The new system has a 1.75-D 1280 channel ultrasound transducer array, 1280 transmission channels, 1280 to 40 mux, and a 40-channel data acquisition board. This new ultrasound system will provide better image and more detailed information of the human breast to help the optical reconstruction.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"1973 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129955052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging of fluid flow velocity using Doppler optical coherence tomography: preliminary results","authors":"D. Piao, N. Chen, Quing Zhu, N. Dutta, L. Otis","doi":"10.1109/NEBC.2001.924717","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924717","url":null,"abstract":"Doppler optical coherence tomography (Doppler OCT) is a technique combining Doppler velocimetry with optical coherence tomography to measure fluid flow velocity at discrete spatial locations. Doppler OCT is an accurate method for the characterization of high resolution (<1 mm/s) fluid flow velocity. Some modifications on current OCT systems have been performed to realize Doppler OCT. Preliminary results on spatial profiles of fluid flow velocity in transparent plastic conduits are presented.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124868170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Kattamis, A. Peslak, S. Ricciardelli, W. Pruehsner, J. Enderle
{"title":"E-Racer, a joystick controlled go-kart","authors":"A. Kattamis, A. Peslak, S. Ricciardelli, W. Pruehsner, J. Enderle","doi":"10.1109/NEBC.2001.924734","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924734","url":null,"abstract":"The E-Racer is an electric go-kart that is controlled through a single joystick, designed for a 13-year old boy who has cerebral palsy. The existing go-kart steering wheel and driving pedals are removed and connected to actuator motors, which are controlled by the joystick and PIC microcontroller.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127073877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Tissue ischemia monitoring using impedance spectroscopy: evaluation of neural networks for ischemia estimation","authors":"J. Songer, S. Kun, S. Makarov","doi":"10.1109/NEBC.2001.924697","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924697","url":null,"abstract":"Tissue impedance spectra and pH values, collected during ischemic episodes in human skeletal muscle, were used to train and test Artificial Neural Networks (NN) for ischemia level estimation. The goal was to determine the NN with optimal performance in classifying impedance spectra and their corresponding pH values when varying levels of noise were introduced to the original signal. The performance of two linear associative memory NNs (Hebbian and ADALINE) and the backpropagation (BP) NN were evaluated using impedance spectra in the frequency range from 25 Hz-500 kHz as inputs and the pH values as outputs. Results indicate that a BP NN with a single hidden layer and moderate numbers of neurons is an optimal solution for the authors' research.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"165 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124624104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing motion in laparoscopic tools","authors":"S. Wolpert, W. Murray, O. Bholat, S. Mastandrea","doi":"10.1109/NEBC.2001.924709","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924709","url":null,"abstract":"A laparoscopic test fixture was implemented to quantify motion and control with a surgical instrument, assess tracking skill acquisition, and provide a basis to compare precision and consistency across a variety of test subjects and conditions. A conventional laparoscopic dissector was fitted with a depth sensor, whose analog output is sampled, processed, and stored using a LabView program on a personal computer. Novice users were tested in simple target approach exercises, using both dominant and non-dominant hands over a seven-day period. Analysis of test data indicated no significant difference in overall precision, but significant differences in approach trajectory, especially during retraction. Data also showed significant improvement in time to complete tasks from day one to day seven. The test fixture was seen to be effective in evaluating a variety of facets of instrument movement and control.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117019682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Child Mobility Car","authors":"A. Russo, W. Pruehsner, J. Enderle","doi":"10.1109/NEBC.2001.924739","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924739","url":null,"abstract":"Child Mobility Car is a small, motorized vehicle that allows a six-year-old girl with cerebral palsy to move about within small areas. Child Mobility Car is a small vehicle about 2 ft. long and 1 ft. wide allowing her to interact far more freely with other children without a cumbersome electric wheelchair. A radio is attached to the car providing a small measure of entertainment for the child as well.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115210896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"CuraSelect: mining complex cDNA libraries for gene specific targets","authors":"M. P. Daley, S. Colman, M. Popp, J. Simons","doi":"10.1109/NEBC.2001.924691","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924691","url":null,"abstract":"In order to accelerate the process of identifying and characterizing genes, a rapid method for gene isolation is essential. One approach is to isolate cDNA clones from a plasmid library. Described here is a process referred to as CuraSelect which uses a small amount of known sequence data from an otherwise unknown gene to target and specifically recover it from a complex cDNA plasmid library. Following this rapid isolation process, the gene of interest is available for sequencing and further characterization studies.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116212440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Arterial Gaussian curvature and the shapes of atherosclerotic plaques","authors":"P. D. Richardson","doi":"10.1109/NEBC.2001.924704","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924704","url":null,"abstract":"Atherosclerotic plaques may form preferentially in parts of arteries that have positive Gaussian curvature, and this may help explain why so many plaques have sharp margins and an elliptic shape when examined en face.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126828584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development of an anatomically correct mechanical model of the bladder","authors":"I. Greenshields","doi":"10.1109/NEBC.2001.924725","DOIUrl":"https://doi.org/10.1109/NEBC.2001.924725","url":null,"abstract":"Viscoelastic models of bladder function have been in existence for many years. Often, such models are referred to either a simple spherical geometric model of the bladder, or to a analytic (but still simplified) model. Here, the authors describe the application of an older viscoelastic model to an anatomically accurate geometry derived from the Visible Human dataset.","PeriodicalId":269364,"journal":{"name":"Proceedings of the IEEE 27th Annual Northeast Bioengineering Conference (Cat. No.01CH37201)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2001-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134531965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}