International journal of phonosurgery and laryngology最新文献

{"title":"Tubercular Laryngitis: A Rebirth?","authors":"R. Nerurkar, Shraddha Singh","doi":"10.5005/jp-journals-10023-1113","DOIUrl":"https://doi.org/10.5005/jp-journals-10023-1113","url":null,"abstract":"Objective: The aim of this study is to highlight the changing clinical patterns of laryngeal tuberculosis (TB) and to increase the awareness of this uncommon manifestation of extrapulmonary TB which will help the clinician in early diagnosis and appropriate management of this condition. Materials and methods: A retrospective analysis was done of 34 suspected cases of tubercular laryngitis who presented to our institution from January 2009 to December 2011. All of these patients were subjected to hematological tests, sputum microscopy, and radiological investigations. Results: Out of these 34 patients, hematological profile, sputum testing, and radiological profile was positive for TB in 13 patients who were started on antitubercular treatment. Out of 13, 1 patient had resolution of cough but persistent hoarseness and was diagnosed as having severe epithelial dysplasia. Twentyone patients were tested negative for TB and were diagnosed as chronic laryngitis (11), histoplasmosis (1), amyloidosis (2), sarcoidosis (1), and invasive squamous cell carcinoma (4). Primary laryngeal TB was diagnosed in two cases. Conclusion: Laryngeal TB, though rare, is increasingly presenting to the otolaryngologists nowadays due to increase in the number of immunocompromised hosts and development of resistant microorganisms. It presents with nonspecific symptoms and can often be missed leading to delay in diagnosis and treatment. Starting empirical steroids without diagnosis may flare up the TB. It often mimics and occasionally may coexist with laryngeal malignancy. Thus the clinician should be vigilant and should always consider laryngeal TB as an important differential for laryngeal lesions.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125461612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ki-67 Index in Salivary Gland Neoplasms","authors":"S. Kaza, T. Rao, Anupama Mikkilineni, G. V. Ratnam, D. Rao","doi":"10.5005/JP-JOURNALS-10023-1110","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10023-1110","url":null,"abstract":"Assessment of proliferation is a means of predicting local recurrence and metastatic potential of malignancies. A mitotic count is not an ideal marker for proliferation in certain situations, such as salivary gland neoplasms. Ki-67 expression as a proliferation marker has been investigated in many human tumors. In the present study, Mitotic index (MI) and Ki-67 index were studied in pleomorphic adenoma, basal cell adenoma, mucoepidermoid carcinoma, adenoid cystic carcinoma epithelial myoepithelial carcinoma, carcinoma ex Pleomorphic adenoma and adenocarcinoma of salivary glands. The results were compared. The MI was similar in benign neoplasms, mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, whereas it was high in carcinoma ex pleomorphic adenoma, adenocarcinoma and adenoid cystic carcinoma. The Ki-67 index was different in basal cell adenoma and pleomorphic adenoma. It was helpful in differentiating high grade and low grade mucoepidermoid carcinoma. It highlighted the malignant behavior of epithelial myoepithelial carcinoma. It was concluded that Ki-67 in benign neoplasms is 5% or less and in malignant ones more than 23% with a few exceptions. In mucoepidermoid carcinoma and epithelial myoepithelial carcinoma, Ki-67 index was found to be a better indicator for aggressiveness. These findings will be presented in this paper, with review of literature.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121952063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subglottic Carcinoma: Treatments and Outcomes","authors":"Nirupoma Moran","doi":"10.5005/JP-JOURNALS-10023-1112","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10023-1112","url":null,"abstract":"Background and objective: Subglottic malignancies are rare. Most of these are predominantly squmous cell carcinoma and common in male. It is usually advanced when initially presented. This study was to analyze the clinical presentation, treatments, and outcomes of subglottic carcinoma. Materials and methods: The study was conducted in the Department of Otorhinolaryngology and Head Neck Surgery, Assam Medical College, Dibrugarh, Assam, India, between March 2014 and September 2015. Results: Of the three patients, two had lymph node metastasis and intralaryngeal involvements. The patients have been followed up till date. All the patients were tracheostomized and received radiotherapy and chemotherapy. Conclusion: Subglottic carcinoma is relatively rare in compari-son with supraglottic and glottic carcinoma. It is presented at advance stage and tend to spread larynx and other organs too.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129274316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Presentation of Syringomyelia","authors":"A. Agrahari","doi":"10.5005/JP-JOURNALS-10023-1118","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10023-1118","url":null,"abstract":"Sudden onset stridor due to bilateral vocal cord paralysis in an adult patient with undiagnosed syringomyelia as a sole presenting symptom is rare. Here we are presenting a case of a 40-year-old female with undiagnosed syringomyelia due to Chiari type I malformation presenting with sudden onset stridor. Even 1 year after decompression surgery, her vocal cord functions did not improve.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"265 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114527380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Extramedullary Plasmacytoma of Soft Tissue Neck","authors":"R. S. Minhas","doi":"10.5005/jp-journals-10023-1119","DOIUrl":"https://doi.org/10.5005/jp-journals-10023-1119","url":null,"abstract":"Plasmacytoma is an extremely rare and discrete solitary mass of neoplastic monoclonal plasma cells. Extramedullary plasmacytoma tends to occur during the fifth and seventh decades of life and is rarely diagnosed in younger patients. In this study, a 55-year-old patient presented to us with complaint of changes in voice, and difficulty in swallowing and breathing. On examination, there was a retropharyngeal mass which is extending to lateral pharyngeal wall and toward nasopharynx. Contrast computed tomography scan shows soft tissue density involving retropharyngeal space and involving nasopharynx and left parapharyngeal space. For this, the patient underwent excision of this mass under General Anaesthesia (GA) biopsy report was suggestive of plasmacytoma. After excluding systemic involvement by means of laboratorial and radiological investigations, the patient was referred to radiotherapy department for complete management.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128765850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcome Analysis in Patients with Benign Vocal Fold Lesions","authors":"Arpit Sharma, J. Dabholkar, Nitish Virmani","doi":"10.5005/JP-JOURNALS-10023-1111","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10023-1111","url":null,"abstract":"Introduction: Benign vocal cord lesions cause significant dysphonia by disrupting the normal vibratory function of the vocal fold mucosa. Multidimensional assessment of voice characteristics allows for an accurate analysis of voice impairment and can be used to assess the outcome of different treatment modalities. Aims: To evaluate the outcome in patients treated for benign vocal fold lesions using multidimensional voice assessment. Materials and methods: Thirty adult patients with benign vocal fold lesions were treated according to standard protocols and followed up for 6 months. Voice was evaluated by visual analog scale (VAS), GRBAS (grade, roughness, breathiness, asthenia, strain) scale, maximum phonation time (MPT), S/Z ratio, and acoustic parameters using PRAAT. Preand posttreatment voice was compared. Results: Benign lesions observed were vocal polyps (16), vocal nodules (7), vocal fold cysts (5), vocal cord papilloma (1), and sulcus vocalis (1). Mean VAS rating improved from 7.5 to 2 at 3 months and 1.6 at 6 months. Mean GRBAS score improved from 7.5 to 2.96 at 3 months and 2.3 at 6 months. Maximum phonation time increased from 9.43 seconds to 14.16 seconds at 3 months and 14.46 seconds at 6 months. S/Z ratio reduced from 1.37 to 1.16 at 3 months and 1.15 at 6 months. Jitter reduced from 1.81 to 1% at 3 months and 0.97% at 6 months; shimmer decreased from 6.07 to 2.19% at 3 months and to 2.03% at 6 months. Harmonic-to-noise ratio values improved from 8.01 to 10.78 dB at 3 months and 10.96 dB at 6 months; mean F0 increased from 207.27 to 217.89 Hz at 3 months and 219.65 Hz at 6 months. Conclusion: A single measurement of voice cannot be used as a reliable outcome measure. Perceptual, aerodynamic, acoustic, and self-analysis together allow a multidimensional assessment of voice characteristics.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"163 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123470872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diverged Otorhinolaryngological Manifestations of Reflux Disease in Indian Condition: A Base Line Data Generation","authors":"R. Jain, Suddhasheel Roy","doi":"10.5005/jp-journals-10023-1114","DOIUrl":"https://doi.org/10.5005/jp-journals-10023-1114","url":null,"abstract":"Aims: To generate base line data of different otorhinolaryngological manifestations of laryngopharyngeal reflux (LPR) disease in Uttar Pradesh, India. Materials and methods: Fifty cases were selected from OPD setup and diagnosed to be having LPR disease based on predefined inclusion and exclusion criteria. They were then explained the necessary details and purpose of the study and were subjected to further standard protocol. The patients with ear complaints were advised pure tone and impedance audiometry. The findings were charted and data extrapolated. Results: Among various complaints, the most common complaint was lump in the throat; others were frequent throat clearing, cough, choking, hoarseness, and excessive throat mucus. The nasal complaints were nasal discharge and blockage, and ear complaints were otalgia and hard of hearing. Laryngoscopy showed hyperemia of larynx and vocal fold edema, ventricular obliteration, laryngeal edema, posterior commissure hypertrophy, thick endolaryngeal mucus, pseudosulcus vocalis and vocal cord granulations. Nasal findings were rhinitis, congestion, and turbinate hypertrophy. Ear complaints had tube dysfunction. On upper gastrointestinal (UGI) endoscopy most of the patients had normal study; some showed esophagitis or hiatus hernia. Mean body mass index of the study population was in normal range. Conclusion: Globus, a common presenting complaint in ENT outdoors is usually related to reflux. Reflux was found associated with Eustachian tube dysfunction and rhinitis. Results demonstrated that obesity and esophagitis are not associated with LPR. Clinical significance: This study investigated a range of parameters responsible for LPR disease. The understanding of the entity of LPR and its manifestations is far from being completely understood. Present-day thrust is in the direction of increasing importance of LPR being recognized in ENT practice. The results and their analyses created an important base line document for the population of the state of Uttar Pradesh (population about 200 million) and adjoining states who commonly call on the Sir Sunderlal Hospital, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116701756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transgender Voice: The Challenges","authors":"A. Roychoudhury","doi":"10.5005/ijopl-6-1-iv","DOIUrl":"https://doi.org/10.5005/ijopl-6-1-iv","url":null,"abstract":"","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127813143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laryngeal Amyloidosis: A Rare Entity causing Hoarseness of Voice","authors":"R. Chandrasekharan, R. Paul, B. John","doi":"10.5005/JP-JOURNALS-10023-1121","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10023-1121","url":null,"abstract":"","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127490361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Localized Laryngeal Amyloidosis","authors":"G. Khaund, Ronica Baruah, Abhijit Kalita","doi":"10.5005/JP-JOURNALS-10023-1116","DOIUrl":"https://doi.org/10.5005/JP-JOURNALS-10023-1116","url":null,"abstract":"Amyloidosis in head and neck is rare but a benign disease. Among the sites in head and neck, larynx is the most commonly involved. A 40-year-old female had presented with hoarseness of voice and dyspnea with a mass in false vocal cord, which was biopsied and diagnosed as amyloidosis. After excluding systemic diseases, final diagnosis of localized laryngeal amyloidosis was given.","PeriodicalId":258448,"journal":{"name":"International journal of phonosurgery and laryngology","volume":"91 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130606703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}