Journal Syifa Sciences and Clinical Research最新文献

Perbandingan Kadar Flavonoid Total Jarak Pagar (Jatropha curcas L.) dan Jarak Merah (Jatropha gossypiifolia L.) 麻疯树和红蓖麻总黄酮含量的比较

Journal Syifa Sciences and Clinical Research Pub Date : 2024-03-20 DOI: 10.37311/jsscr.v5i3.23896

Hamsidar Hasan, Faramita Hiola, Fika Nuzul Ramadhani, Mahdalena Sy. Pakaya, Rahmatiya Imran Tululi

{"title":"Perbandingan Kadar Flavonoid Total Jarak Pagar (Jatropha curcas L.) dan Jarak Merah (Jatropha gossypiifolia L.)","authors":"Hamsidar Hasan, Faramita Hiola, Fika Nuzul Ramadhani, Mahdalena Sy. Pakaya, Rahmatiya Imran Tululi","doi":"10.37311/jsscr.v5i3.23896","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.23896","url":null,"abstract":"Flavonoids are a group of phytochemical compounds commonly found in plants. Jatropha curcas L. And Jatropha gossypiifolia L. Are plants belonging to the same family, Euphorbiaceae. Both of these plants have significant potential, especially in health. This research aims to determine the comparison of total flavonoid levels in methanol extracts of Physic Nut (Jatropha curcas L.) and Cotton-Leaf Physic Nut (Jatropha gossypiifolia L.) leavs using U-Vis spectrophotometry method. This research utilizes both qualitative and quantitative analysis methods. The qualitative analysis involves phytocemical screening and Thin-Layer Chromatography analysis using an eluent of n-Hexane ethyl acetate with a ratio of (8:2). The quantitative analysis in this research utilized the UV-Vis spectrofotometry method at a wavelength of 435 nm with quercetin as the standard comparator. The results indicate that the average total flavonoid content in 100 mg of methanol extract from Physic Nut (Jatropha curcas L.) leaves is 5,75% w/v. Meanwhile, in the methanol extract from Cotton-Leaf Physic Nut (Jatropha gossypiifolia L.) leaves, it is 7,20% w/v. Based on Independent Sample T-test statistical analysis, the total flavonoid content in the methanol extract from Cotton-Leaf Physic Nut leaves is significantly higher than that in the methanol extract from Physic Nut Leaves, indieating a significant difference in the average values of two samples (p-value0,05).","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"66 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140224031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifikasi Layanan Kesehatan yang dibutuhkan Pasien Lansia untuk Menunjang Kepatuhan Minum Obat 确定老年患者所需的医疗服务以支持坚持用药

Journal Syifa Sciences and Clinical Research Pub Date : 2024-02-26 DOI: 10.37311/jsscr.v6i1.24599

A.Takdir Makkulawu, Multiani S. Latif

{"title":"Identifikasi Layanan Kesehatan yang dibutuhkan Pasien Lansia untuk Menunjang Kepatuhan Minum Obat","authors":"A.Takdir Makkulawu, Multiani S. Latif","doi":"10.37311/jsscr.v6i1.24599","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.24599","url":null,"abstract":"Healthcare services are one of the factors influencing the medication adherence of elderly patients. Therefore, in order to enhance the medication adherence of elderly patients, it is essential to understand the healthcare services required by the elderly, both from healthcare professionals and the healthcare system. This research aims to identify the necessary healthcare services for the elderly to improve their adherence. The method employed is in-depth interviews using validated interview guidelines, followed by analysis through thematic analysis. A total of 12 elderly patients suffering from diabetes mellitus were involved in this study, ranging in age from 56 to 70 years. The forms of healthcare services needed by these elderly patients include insurance-covered treatment costs with an easy and practical system, information about medications delivered by experts, the presence of methods or tools for medication reminder, healthcare professionals who understand the elderly, education about medications and diseases, as well as specialized facilities to obtain medications. This study is a qualitative research effort, with the hope that further research can be conducted to serve as a foundation for both central and regional governments in formulating policies related to the healthcare services required by the elderly.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"47 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140429387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efektivitas Fraksi Metabolit Sekunder Jamur Endofit Lamun (Thalassia hemprichii) dari Kawasan Teluk Tomini Sebagai Antibakteri Jerawat 托米尼湾海草内生真菌（Thalassia hemprichii）的次级代谢物馏分作为痤疮抗菌剂的功效

Journal Syifa Sciences and Clinical Research Pub Date : 2024-02-19 DOI: 10.37311/jsscr.v6i1.21457

Mahdalena Sy. Pakaya, Fika Nuzul Ramadhani, Moh. Ridwan Ente

{"title":"Efektivitas Fraksi Metabolit Sekunder Jamur Endofit Lamun (Thalassia hemprichii) dari Kawasan Teluk Tomini Sebagai Antibakteri Jerawat","authors":"Mahdalena Sy. Pakaya, Fika Nuzul Ramadhani, Moh. Ridwan Ente","doi":"10.37311/jsscr.v6i1.21457","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.21457","url":null,"abstract":"Endophytic fungi live in their host tissues, so that endophytic fungi can produce secondary metabolites that are similar to their hosts as well. In this case, the use of endophytic fungi can reduce the exploitation of seagrass populations (Thalassia hemprichii) in Tomini Bay. This study aims to examine the effectiveness of the secondary metabolite fraction of the endophytic seagrass fungus (Thalassia hemprichii) from Tomini Bay against acne-causing bacteria. The test method used is disc diffusion method (Kirby Bauer), by measuring the inhibition zones of the ethanol fraction, ethyl acetate fraction, and the N-hexan fraction of the secondary metabolite fraction of endophytic fungi against acne-causing bacteria. The liquid-liquid partition results of the secondary metabolites of seagrass endophytic fungi from the Tomini Bay area were the N-Hexan fraction of 3.06 grams, the Chloroform fraction of 2.90 grams, and the Ethyl Acetate fraction of 1.53 grams. While the effectiveness test of the N-Hexan, Chloroform, and Ethyl Acetate fractions of secondary metabolites of endophytic seagrass microbes from the Tomini Bay area showed that the N-Hexan fraction at a concentration of 75% had greater inhibition on each of the acne-causing bacteria, namely Propionibacterium acne 17 .33 mm (strong category), Staphylococcus aureus 17.86 mm (strong category), and Staphylococcus epidermidis 16.01 mm (strong category).","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"28 31","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140450074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Review Artikel : Aktivitas Antibakteri Daun Mangkokan (Nothopanax scutellarium) 文章回顾：莽草叶的抗菌活性

Journal Syifa Sciences and Clinical Research Pub Date : 2024-02-06 DOI: 10.37311/jsscr.v5i3.24321

Milla Oktaviani, Siskha Al Zahra

引用次数: 0

Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Daun Ketepeng Cina (Cassia alata L) Terhadap Jamur Pityrosporum ovale 决明子叶提取物抗卵孢子菌洗发水活性测试

Journal Syifa Sciences and Clinical Research Pub Date : 2024-02-06 DOI: 10.37311/jsscr.v5i3.24310

A. Suryani, Eneng Ikrimah Rohwah

{"title":"Uji Aktivitas Sediaan Sampo Antiketombe Ekstrak Daun Ketepeng Cina (Cassia alata L) Terhadap Jamur Pityrosporum ovale","authors":"A. Suryani, Eneng Ikrimah Rohwah","doi":"10.37311/jsscr.v5i3.24310","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.24310","url":null,"abstract":"Dandruff is a health problem that is often experienced by most people because it can reduce self-confidence. The aim of this research is to determine the extract of Chinese ketepeng leaves (Cassia alata L) as an anti-dandruff shampoo preparation and to determine the activity of the shampoo against Pityrosporum ovale and Candida albicans fungi using laboratory experimental methods. This research is divided into three concentration variations, namely 10% - 15% 20% and two supporting controls, namely control (-) without extract and control (+), namely ketomed shampoo. Results: The results of the research for the inhibitory power of the fungus Pityrosporum ovale without extract (-) have a value of 4.43 mm at a concentration of 10% have an inhibition zone of 17.23 mm at a concentration of 15% have an inhibitory zone value of 18.67 mm at a concentration of 20% have the value of the inhibition zone is 19.66 mm in the control (+) which has a value of 20.87 mm. In Candida albicans without extract (-) it has a value of 2.33 mm at a concentration of 10% it has an inhibition zone value of 16.44 mm at a concentration of 15% it has an inhibition zone value of 17.76 mm at a concentration of 20% it has an inhibition zone value of 19.37 mm at control (+) has a value of 20.54 mm. Chinese ketepeng (Cassia alata L.) leaf extract can be used as an anti-dandruff shampoo, based on the results of the preparation evaluation it was found that the formula with a concentration of 15% meets the characteristics of a good shampoo, and the flavonoid compound content in Chinese Ketapang (Cassia alata L.) leaf extract is 15% has a high zone of inhibition against P. ovale and C. albicans fungi. So it can be concluded that the best formula obtained in this study was at an extract concentration of 15%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"41 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140461116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perbandingan Flavonoid Total pada Ekstrak Biji Pepaya (Carica papaya L.) Varietas Bangkok dan California 曼谷和加利福尼亚木瓜（Carica papaya L.）种子提取物中总黄酮类化合物的比较

Journal Syifa Sciences and Clinical Research Pub Date : 2024-01-30 DOI: 10.37311/jsscr.v5i3.21871

M. Taupik, A.Takdir Makkulawu, Fahrul Ilham, Arini Saman

{"title":"Perbandingan Flavonoid Total pada Ekstrak Biji Pepaya (Carica papaya L.) Varietas Bangkok dan California","authors":"M. Taupik, A.Takdir Makkulawu, Fahrul Ilham, Arini Saman","doi":"10.37311/jsscr.v5i3.21871","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.21871","url":null,"abstract":"Barely used by the community, papaya seeds (Carica papaya L.) astonishingly contain flavonoid compounds that can be turned into antioxidants to counter free radicals. However, the amount of flavonoids in papaya depends on where it grows. Types of papaya (Carica papaya L.) that are often grown and consumed by the Gorontalo community are Bangkok and California varieties. Therefore, this study aims to analyze the levels of flavonoid compounds in papaya seeds (Carica papaya L.) of Bangkok and California varieties grown in Gorontalo province using UV-Vis spectrophotometry instruments. Qualitative analysis in this study is conducted through phytochemical screening methods. Meanwhile, the quantitavie analysis uses the UV-Vis spectrophotometry method at 419 nm wavelength with quercetin’s standard comparison solution. The result discloses that highest average flavonoid compound of papaya seed extract (Carica papaya L.) is in Bangkok variety with 10,197% w/v, followed by the California variety with 3,475% w/v. Bangkok and California papaya seed extracts have met validation standards with correlation coefficient values of 0,9991, regression function coefficient values (Vx0) 0f 2,1%, %retrieval values of Bangkok papaya seed extract is 100,05% and California is 101, 29%, RSD% values for Bangkok papaya seed ethanol extract is 1,775% and California is 1,348%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"30 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140482153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Isolasi dan Uji Aktivitas Antioksidan Minyak Atsiri Daging Buah Pala (Myristica fragrans) 肉豆蔻（Myristica fragrans）果肉精油的分离和抗氧化活性测试

Journal Syifa Sciences and Clinical Research Pub Date : 2024-01-26 DOI: 10.37311/jsscr.v5i3.24109

Muh Nasir, Eri Marwati

{"title":"Isolasi dan Uji Aktivitas Antioksidan Minyak Atsiri Daging Buah Pala (Myristica fragrans)","authors":"Muh Nasir, Eri Marwati","doi":"10.37311/jsscr.v5i3.24109","DOIUrl":"https://doi.org/10.37311/jsscr.v5i3.24109","url":null,"abstract":"Nutmeg is considered an important ingredient of various industrial applications ranging from food to cosmetics. The pharmaceutical product is also important for its antioxidant and antimicrobial properties. Further research is needed to isolate and identify the bioactive compounds of Myristica fragrans. The aim of this research was to isolate and determine the antioxidant activity of the essential oil of nutmeg flesh (Myristica fragrans). The sample used was nutmeg flesh (Myristica fragrans) taken from Ternate Island, North Maluku. The essential oil of nutmeg flesh was isolated using water vapor distillation and the antioxidant activity was tested using the DPPH method. All data are presented as mean ± standard deviation (SD) and were carried out in triplicate. The results of the research showed that the isolation of nutmeg essential oil obtained with a yield of 0,32%. Organoleptically, the essential oil of nutmeg flesh obtained from the steam distillation process has quality that meets SNI, in the form of a clear to rusty liquid and has a distinctive odor. Phytochemical tests obtained that the essential oil of nutmeg flesh contains alkaloids, flavonoids and steroids, and does not contain polyphenols and saponins. The concentration of essential oil increases, the absorption value and percent inhibition increase so that an average IC50 value of 49,34 ppm is obtained. The essential oil of nutmeg flesh by steam distillation obtained a yield of 0,32% and has antioxidant activity which is classified as a strong antioxidant","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"38 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140494304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analisis Natrium Benzoat dan Rhodamin B Pada Saos Tomat Pasaran yang Beredar di Kota Gorontalo 戈伦塔洛市市场上流通的番茄酱中苯甲酸钠和罗丹明 B 的分析

Journal Syifa Sciences and Clinical Research Pub Date : 2024-01-24 DOI: 10.37311/jsscr.v6i1.23386

Ishak Isa, M. Taupik, Lilis Lebie, Fahrul Ilham

{"title":"Analisis Natrium Benzoat dan Rhodamin B Pada Saos Tomat Pasaran yang Beredar di Kota Gorontalo","authors":"Ishak Isa, M. Taupik, Lilis Lebie, Fahrul Ilham","doi":"10.37311/jsscr.v6i1.23386","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.23386","url":null,"abstract":"Sodium benzoate is the sodium salt of benzoic acid which is often used in food ingridiends, for example in tomato sauce. In foodstuffs, sodium benzoate will break down into its active from or benzoate acid. However, the use of sodium benzoate should not exceed 0,1% in food ingedients. Meanwhile, Rhodamin B is a textle and pape day where this substance is very harmful if inhald, in contact with skin. In eyes and swallowed. The research aimed to determine the amount of sodium benzoat and rhodamin B in tomato sauce circulating in Gorontalo City. The samples of tomato sauce were obtained randomly from three markets in Gorontalo City regardless of its conditions whether those who did not have circulation permit or did not have obvious composition and BPOM permit. The method for determinating sodium benzoate and rhodamine B levels was carried out using UV-Vis spectrophotometry. The results obtained were sodium benzoate preservative levels in the three samples were 0,9363 g/kg in sample A, 1,5469 g/kg in sample B, and 1,8725 g/kg in sample C. Meanwhile, the rhodamine B levels in the three samples were 0,7515 in sample A, 1,5015 in sample B, and 1,5833 in sample C. Based on the results of this concentration calculation, it is observable that all samples have exceeded the threshold for using sodium benzoate and rhodamine B.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"48 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140497469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Standardisasi dan Pengukuran Kadar Flavonoid Daun Ketepeng Kecil (Senna tora (L.) Roxb.) Menggunakan Metode Spektrofotometri UV-Vis 用紫外-可见分光光度法标准化和测量小叶番泻叶（Senna tora (L.) Roxb.）中的类黄酮含量

Journal Syifa Sciences and Clinical Research Pub Date : 2024-01-21 DOI: 10.37311/jsscr.v6i1.15926

Mahdalena Sy. Pakaya, Ishak Isa, M. Taupik, Mohamad Aprianto Paneo, Aldawaty I. Ahyar

{"title":"Standardisasi dan Pengukuran Kadar Flavonoid Daun Ketepeng Kecil (Senna tora (L.) Roxb.) Menggunakan Metode Spektrofotometri UV-Vis","authors":"Mahdalena Sy. Pakaya, Ishak Isa, M. Taupik, Mohamad Aprianto Paneo, Aldawaty I. Ahyar","doi":"10.37311/jsscr.v6i1.15926","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.15926","url":null,"abstract":"Sickle senna (Senna tora (L.) Roxb.) is a wild plant that is used by the community as a traditional medicine to treat diarrhea and intestinal worms. In the development of plants as traditional medicines, it is necessary to standardize the quality of plant materials to ensure their quality, stability, and safety. This study aims to determine the standadization of extracts both specifically and non-specifically and to determine the level of falvonoids in the fraction of sickle senna (Senna tora (L.) Roxb.) leaves. This study applies a phytochemical screening test, specific parameter test, non-specific parameter test, and flavonoid levels determination. The result of phytochemical screening shows that the fraction containing flavonoid compounds is 70% ethanol fraction. The results of standardization for specific parameter show the organoleptic ethanol fraction of 70% is in the form of semi-solid/viscous, black color and distinctive smell, with water soluble extract content is 19.08%, and ethanol soluble extract content is 23.35%. the standardization result for non-specific parameter shows that the total ash content is 1.76%, the acid insoluble ash content is 2.890%, drying shrinkage is 4.96%, and water content is 18.80%. meanwhile, metal and microbial contamination show no contamination in the 70% ethanol fraction. The result for the analysis of the flavonoid content of the 70% ethanol fraction. The result for the analysis of the flavonoid content of the 70% ethanol fraction of sickle senna leaves is carried out at a wavelength of 438.36 nm with an absorbance value of 0.0154. The total flavonoid level is calculated by the standard linear equation of quarcetin, which is y=0.0648x + (-0.0232) with a correlation coefficient (r2) = 0,9948 and a total flavonoid content of 4.713%","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Profil Kesesuaian Terapi Obat Pada Pasien Dispepsia di Ruangan IGD RSUD dr. Zainal Umar Sidiki RSUD 急诊室消化不良患者的药物治疗适宜性概况 Zainal Umar Sidiki 博士

Journal Syifa Sciences and Clinical Research Pub Date : 2024-01-21 DOI: 10.37311/jsscr.v6i1.23822

T. S. Tuloli, Nur Rasdianah, W. Abdulkadir, Wiwit Zuriati Uno, Silvana Pandju

{"title":"Profil Kesesuaian Terapi Obat Pada Pasien Dispepsia di Ruangan IGD RSUD dr. Zainal Umar Sidiki","authors":"T. S. Tuloli, Nur Rasdianah, W. Abdulkadir, Wiwit Zuriati Uno, Silvana Pandju","doi":"10.37311/jsscr.v6i1.23822","DOIUrl":"https://doi.org/10.37311/jsscr.v6i1.23822","url":null,"abstract":"Dyspepsia is an upper gastrointestinal symptom complex that has symptoms of fulllness after eating, early satiety, or epigastric pain of burning without any sturctural cause. The research aims to determine the suitability of drug therapy based on the right patient, the right drug, and the right dose in the emergency room at dr. Zainal Umar Sidiki Regional Public Hospital, North Gorontalo Regency. This research is descriptive research with retrospective data collection. The data used were obtained from medical records of patients in the ER, with 215 patients whose paatient characteristics were processed using the Microsoft Excel program. The results showed that most dyspepsia patients were female, namely 124 (58%), the age range 50-60 years was 74 (34%). The most widely used therapy is combination therapy 154 (72%). The largest variation in the number of single drug uses Inj. Omeprazole amounted to 34 (16%), and a combination of two types of drugs that are widely used, namely Inj. Omeprazole with Inj. Ondansetron has a total of 36 (17%) and a combination of three types of drugs that are widely use, including PPIs, cytoprotectants, and prokinetics, totaling 23 (11%). The rationality of the right patient treatment was 53,48%, the right medicstion was 78%, and the right dose was 100%. In conclusionm the appropriateness of therapy based on the right patient was 53,48%, the right drug was 78%, and the right dose was 100%.","PeriodicalId":257265,"journal":{"name":"Journal Syifa Sciences and Clinical Research","volume":"82 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140501235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0