Russian Journal of Geriatric Medicine最新文献

{"title":"Pathogenetic and Clinical Relationships between Chronic Obstructive Pulmonary Disease, Sarcopenia and Frailty","authors":"V. A. Sergeeva, N. Runikhina","doi":"10.37586/2686-8636-1-2024-40-48","DOIUrl":"https://doi.org/10.37586/2686-8636-1-2024-40-48","url":null,"abstract":"The  impact  of  aging and geriatric syndromes on  chronic obstructive pulmonary disease, a  complex, chronic inflammatory condition, is a subject of significant interest in aging medicine. Understanding the key pathogenic mechanisms that combine the aging process and chronic obstructive pulmonary disease can help rethink therapeutic concepts in patients with the described comorbidity and be considered the basis of new directions for preventive measures.The purpose of the review is to update data from open access scientific sources on the pathogenetic mechanisms and clinical relationships of chronic obstructive pulmonary disease, sarcopenia, and frailty.Methods. Foreign and domestic scientific publications on this topic over the past 15 years were analyzed using electronic libraries PubMed/MedLine, Elsevier, elibrary.Conclusion. An  extensive examination  of  current scientific data  was carried out to  determine the pathogenetic connections between chronic obstructive pulmonary disease and the aging process, along with the prominent geriatric conditions of sarcopenia and frailty. A significant amount of information has been accumulated indicating deterioration in the clinical manifestations and prognosis of older patients with a combination of the described pathologies; therefore, the relevance of further study of these comorbidities remains. The cause-and-effect relationship of these clinical manifestations remains not entirely clear: chronic obstructive pulmonary disease leads to  the development of  sarcopenia and frailty, or  these geriatric syndromes only accompany chronic obstructive pulmonary disease, as  a disease that manifests itself most frequently in advanced age. There is significant interest in developing therapeutic strategies to improve the clinical outcomes of older patients with a combination of chronic obstructive pulmonary disease, frailty and sarcopenia.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":"74 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140724805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Geriatric Assessment of Older and Oldest-Old Patients in the Perioperative Period. Russian Gerontology Research and Clinical Centre Experience","authors":"A. V. Luzina, A. Y. Mozgovykh, N. Runikhina, O. N. Tkacheva","doi":"10.37586/2686-8636-4-2023-233-238","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-233-238","url":null,"abstract":"With the aging population, the significance of preoperative diagnostics and optimizing the treatment of surgical patients with frailty syndrome is gaining momentum. For such patients a comprehensive geriatric assessment (CGA) is carried out to clarify the severity of frailty and the individual characteristics of the geriatric status [1]. The results of this assessment are used to stratify the risk in the postoperative period and to determine targeted interventions for the correction of geriatric syndromes [2]. The introduction of new geriatric technologies during hip and knee replacement in weakened older patients needs scientific justification and confirmation of effectiveness.Objective: to test the method of complex geriatric management of older and oldest-old patients before and after surgical interventions in the provision of planned inpatient orthopedic care (knee and hip arthroplasty).Materials and methods: the study involved two groups of older and oldest-old patients with frailty: 50 patients, average age 69.2 ± 6.0 years [60 to 87 years] with gonarthrosis and 50 patients, average age 67.6 ± 5.5 years [60 to 81 years] with coxarthrosis. At the prehospital stage, patients were diagnosed with frailty, in accordance with the clinical recommendations of «Senile asthenia» [3]. Upon admission to surgical treatment, a CGA was performed, including indicators of basic (Barthel Activities of daily living Index, Barthel scale [4]) and instrumental activity (The Instrumental Activities of Daily Living Scale, IADL scale [5]), nutrition assessment (Mini Nutritional assessment, MNA scale [6]), cognitive functions (The Montreal Cognitive Assessment, MOCA test [7]), depression (Geriatric Depression Scale, GDS-15 scale [8]), as well as quality of life (A Visual Analogue Scale, EQ-VAS scale [9]), multimorbidity and polypragmasia. An  individual plan of  perioperative management was drawn up.Results. A  comparative analysis demonstrated statistically significant improvements in  functional status (based on  the Barthel scale), cognitive status (based on the MOCA test), nutritional status (based on the MNA scale) and quality of life (based on the EQ-VAS scale) 12 months after surgical intervention in groups of patients after knee and hip replacement. In the group of patients after hip replacement, there was also an improvement in the quality of life of patients 12 months after surgery. The assessment and dynamics of indicators in functional and cognitive status within the control group were not carried out, which makes it difficult to compare the results. However, there was a reduction in hospital stay for patients using geriatric approaches compared with previously used surgical care in the control group.Conclusion: the management of  patients with frailty in  the perioperative period with the use of  CGA allows for preventive measures aimed at  maintaining functional, psycho-emotional status. Individual characteristics of  the state of psychoemotional and f","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":"2 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139616736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Uroselective α1A-Adrenoceptor Antagonist Tamsulosin in Treatment Lower Urinary Tract Symptoms in Men with Benign Prostatic Hyperplasia","authors":"G. Krivoborodov, N. S. Efremov, D. A. Shirin, A. A. Gontar, O. N. Tkacheva","doi":"10.37586/2686-8636-4-2023-295-300","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-295-300","url":null,"abstract":"Lower urinary tract symptoms suggestive of benign prostatic hyperplasia (LUTS/BPH) is a common condition in older man. Uroselective a1a-adrenoceptor (AR) antagonists tamsulosin and tamsulosin modified release (OCAS) are the most frequently prescribed medications for the men with LUTS due to BPH. Both tamsulosin and tamsulosin OCAS improve the patients disease-specific quality of life, reduce IPSS by approximately 30–40% and increase Qmax by approximately 20– 25%. The high selectivity of tamsulosin to α1А-adrenoceptor and slow release system OCAS provide a minimal vasodilating effect and correspondingly low risks of falls. These benefits are important in the treatment of LUTS in older men.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":"44 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Modern Cardiac-Specific Biomarkers in Assessing the Risk of Developing Complications of Cardiovascular Diseases During Surgical Operations Not Related to Cardiac Intervention","authors":"E. Alimova, S. Gilyarevsky, K. Eruslanova, Yulia V. Kotovskaya","doi":"10.37586/2686-8636-4-2023-254-260","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-254-260","url":null,"abstract":"Despite significant tactic’s improvements of perioperative management of patients undergoing non-cardiac surgery, there is still a high incidence of postoperative complications. So more accurate risk stratification is necessary before surgery in order to possibly reduce such risk. In addition to assessing the risk associated with surgery, the risk associated with the patient, which may be due to the presence of certain diseases, primarily cardiovascular, is also assessed. There are currently evidences of the validity of determining the level of biomarkers in the blood in certain groups of patients during operations not related to cardiac intervention, which makes it possible to clarify the scope of necessary diagnostic interventions in preparation for surgery, as well as to diagnose complications of heart disease in the postoperative period.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":"29 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nursing Protocol: Management of Older and Oldest-Old Patients Living with Frailty Syndrome in the Perioperative Period","authors":"O. N. Tkacheva, N. V. Sharashkina, M. M. Balaeva, K. Eruslanova, N. Runikhina, Yulia V. Kotovskaya","doi":"10.37586/2686-8636-4-2023-301-304","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-301-304","url":null,"abstract":"In this article, the authors discuss the principles of perioperative management of patients in the older age group with frailty syndrome. Most patients with frailty syndrome have several chronic diseases; associations of  frailty with cardiovascular diseases are known — arterial hypertension, coronary heart disease, chronic heart failure, as well as with diabetes mellitus, chronic kidney disease, diseases of the joints and lower respiratory tract, oncological diseases, which causes a higher risk of  complications in  the postoperative period and requires a  special approach in  the perioperative period. This protocol addresses the issues of preventing complications and preserving the patient’s autonomy after surgical treatment.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":"3 24","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139616726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced STOPP/START Criteria: A Tool for Managing Polypharmacy in Older Population","authors":"Yulia V. Kotovskaya, O. N. Tkacheva, N. Runikhina, M. Cherniaeva, I. Malaya, O. Maslennikova, L. A. Egorova, A. A. Dotsenko","doi":"10.37586/2686-8636-4-2023-273-288","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-273-288","url":null,"abstract":"Polypharmacy in geriatric patients is associated with an increased risk of adverse outcomes. Therefore, several instruments for prescription analysis and optimization can be used to enhance the safety and efficacy of pharmacotherapy in old age population. STOPP/START criteria is one of the most popular screening tools in the Russian Federation and abroad that list potentially inappropriate drugs for use in older patients (STOPP criteria) and potentially prescribed for certain clinical cases (START criteria). Two previous versions of the STOPP/START criteria were published in 2008 and 2015. Released in 2023, the newest (third version) demonstrates the evolution of evidence-based pharmacotherapy for older and oldestold patients, featuring 133 STOPP and 57 START criteria. Expanding the base of STOPP/START criteria should support optimization of prescriptions and reducing ADRs risk in older patients. This article introduces translation of STOPP/START criteria, version 3.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":" 1019","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139617372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RUSS-AGE: developed research protocol for the creation of Russian biological age calculators","authors":"A. A. Melnitskaia, L. Matchekhina, O. N. Tkacheva, A. K. Ilyushchenko, A. A. Tyazhelnikov, V. S. Polunin, A. V. Yumukyan, I. Strazhesko","doi":"10.37586/2686-8636-4-2023-239-247","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-239-247","url":null,"abstract":"Background. Life expectancy is  increasing around the globe. However, chronological age is  not the best indicator of  health. For a  more accurate assessment of  body condition throughout life, in  general, and aging, in  particular, and identify potential points of geroprotective intervention, a specialized tool is needed. A tool that could prove beneficial is a biological age calculator, utilizing a range of biomarkers to analyze the degree of functional preservation of the body. Many existing biological age calculators are limited by a small number of parameters to analyze and sensitivity to use in a specific population.Aim. Large-scale studies to create a mathematical model for calculating biological age based on the Russian population have not previously been carried out. In 2022, the RUSS-AGE study was launched to create biochemical, cognitive and microbiotic calculators of biological age and determine possible points of geroprotective interventions.Materials and methods. The study intends to  enroll at  least 3,500 participants and analyze more than a  hundred biomarkers using laboratory tests, questionnaires, neurocognitive and functional testing, and collection of anthropometric and physical indicators.Results. Currently, the recruitment of participants is supported by a government grant under the Priority 2030 program. By November 2023, 510 participants had been enrolled in the study.Conclusion. Further statistical processing of the information received and the development of prototypes of biological age calculators are planned.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":" 931","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139617587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Guidelines for Perioperative Care of Older and Oldest-Old Patients Living with Frailty Undergoing Elective Surgery","authors":"O. N. Tkacheva, N. Runikhina, Yulia V. Kotovskaya, S. Gilyarevsky, L. Aleksanyan, A. V. Rozanov, A. A. Pronchenko, A. Y. Molchanova, K. Eruslanova, A. Naumov, N. M. Vorobyova, E. Mkhitaryan, M. Cherdak, A. A. Galaeva, N. V. Sharashkina, V. S. Ostapenko, M. R. Khokonov, I. Sirotin, G. Krivoborodov, A. Z. Khashukoeva, G. O. Andreasyan, I. G. Chulovskaya, A. Magdiev, D. V. Kolesnikov, V. Y. Vlasov, E. V. Prusov, A. F. Farzutdinov, N. O. Khovasova, E. Dudinskaya, M. M. Balaeva, A. Y. Shchedrina, L. Merkusheva, E. Ivannikova, R. I. Isaev","doi":"10.37586/2686-8636-4-2023-218-232","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-218-232","url":null,"abstract":"The population of older and oldest-old individuals is increasing at a rapid pace, leading to a notable proportion of this age group requiring surgical procedures due to multimorbidity. It is known that, compared with young people, patients over 60 have a whole set of factors, such as decreased physiological functions, the presence of several concomitant diseases, polypharmacy, cognitive dysfunction and specific geriatric syndromes, which may lead to  a higher risk of  postoperative complications and prolonged recovery. Therefore, an integrated multidisciplinary approach on management is necessary for this group of patients, but the use of such an approach is currently rare. The purpose of this document is to review the literature, summarize current recommendations, and provide a  set of  expert recommendations to  assist practicing geriatricians, surgeons, anesthetists, and allied health professionals.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":" March","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139618037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rehabilitation Programs for Older Surgical Patients in the Postoperative Period","authors":"M. S. Arefieva, K. Eruslanova, N. Runikhina, Yulia V. Kotovskaya, A. V. Luzina","doi":"10.37586/2686-8636-4-2023-261-272","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-261-272","url":null,"abstract":"In  recent years, Russia has seen an  increase in  the proportion of  older patients receiving surgical care. In  the majority of cases, an older patient is burdened with multiple long-term conditions (MLTC) and geriatric syndromes. To improve the consensus clinical and / or functional outcomes after surgery, rehabilitation measures are required in the postoperative period. In this review, spanning the last 10 years, the value of rehabilitation programs for older and oldest-old patients was assessed. The clinical effectiveness of multidisciplinary rehabilitation measures in the postoperative period is analyzed.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":"58 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139527821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Laxatives in Geriatric Practice: From Preoperative Bowel Preparation to Correction of Chronic Constipation","authors":"V. S. Ostapenko","doi":"10.37586/2686-8636-4-2023-289-294","DOIUrl":"https://doi.org/10.37586/2686-8636-4-2023-289-294","url":null,"abstract":"The first part of  the article discusses the issues of  preoperative bowel preparation in  older and oldest-old patients, with a  particular emphasis on  the safest drugs. The second part of  the article presents the problem of  chronic constipation as a geriatric syndrome, including a description of age-associated changes in the structure and function of colon, causes of constipation and features of correction in geriatric practice.","PeriodicalId":256357,"journal":{"name":"Russian Journal of Geriatric Medicine","volume":" 834","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139617418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}