The Libyan Journal of Medicine最新文献

{"title":"Propranolol, infantile haemangiomas, and serendipity: new use for an old drug","authors":"V. Grech, C. Scerri","doi":"10.3402/ljm.v6i0.5826","DOIUrl":"https://doi.org/10.3402/ljm.v6i0.5826","url":null,"abstract":"Capillary haemangiomas are benign lesions that may occur anywhere on the skin, may grow rapidly in the first two years of life and may impair vital organs. Propranolol has been recently discovered to shrink these lesions effectively. We report the first such patient treated in Malta with this drug.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"2020 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121453507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical practice and selling of drugs during Ramadan","authors":"Y. Jarrar","doi":"10.3402/ljm.v6i0.5775","DOIUrl":"https://doi.org/10.3402/ljm.v6i0.5775","url":null,"abstract":"Ramadan is a holy month where Muslims fast from sunset to sunrise. During the fasting days of Ramadan, glucose homeostasis is maintained by meals taken before dawn and by liver glycogen stores. Changes in serum lipids are variable and depend on the quality and quantity of food consumption and changes in weight. Increases in subjective sensations of fatigue, loss of sleep, or disruption of normal sleep have been reported as physiological changes during fasting in Ramadan. Also, fasting during Ramadan was reported to reactivate and aggravate gastrointestinal diseases, exacerbate migraines, and increase the circadian pattern of strokes. In Jordan, changes in the pharmaceutical practice and selling of drugs were recognized by many local pharmacy owners during Ramadan. However, there are no studies about it. (Published: 1 January 2011) Citation: Libyan J Med 2011, 6 : 5775 - DOI: 10.3402/ljm.v6i0.5775","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2011-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129571673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Importance of Haemoglobin Measurement for Selection of Blood Donors in Libya","authors":"A. Abud, A. Bashein, A.A. Msalati","doi":"10.3402/ljm.v4i4.4837","DOIUrl":"https://doi.org/10.3402/ljm.v4i4.4837","url":null,"abstract":"In Libya, haemoglobin estimation is not used routinely to assess the fitness of blood donors. We examined the importance of including this parameter in donor selection. Venous blood samples were collected from the bleed line at the end of the donation process from 1339 healthy adult male blood donors, aged 18–60 years, in Al-Jala Women Hospital in Tripoli, Libya. Haemoglobin concentration was measured using an automated haematology analyzer. The main donor age categories were 21-30 and 31-40 years (49.5% and 37%, respectively). Blood donation was mainly a replacement donation. The mean ±2SD range for haemoglobin was 10.8–17.0 g/dl. 27.2% of the donors had haemoglobin concentration of less than 13 g/dl, 16.9% of them had less than 12.5 g/dl and 1.9% had less than 10.8.5 g/dl. Our results suggest that it is important to include haemoglobin estimation as a routine procedure in selection of blood donors.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130074066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Young Man with Multiple Pulmonary Cysts","authors":"WH Ibrahim, A. Al-Muzrkchi, M. Al-Maslamani","doi":"10.3402/ljm.v3i3.4783","DOIUrl":"https://doi.org/10.3402/ljm.v3i3.4783","url":null,"abstract":"Several diseases cause cystic or cyst-like parenchymal lung abnormalities including adult pulmonary Langerhan’s cell histiocytosis (PLCH), lymphangioleiomyomatosis (LAM), emphysema, end-stage interstitial lung disease, and cystic bronchiectasis. Many of these diseases can now be diagnosed with high accuracy by the use of high-resolution computerized tomography (HRCT). In fact, HRCT of chest has proved a major breakthrough in the diagnosis of these diseases. We are presenting a young man with a cystic lung disease in which, the HRCT findings were virtually diagnostic of that disease. The clinical and HRCT findings of this disease along with its differential diagnosis are discussed in this paper.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127806370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Introspection by a Medical Teacher on the Present Status of Medical Education in Libya","authors":"D. Sheriff","doi":"10.3402/LJM.V4I4.4836","DOIUrl":"https://doi.org/10.3402/LJM.V4I4.4836","url":null,"abstract":"To The Editor: I had the privilege of teaching in Garyounis Medical University and then Al Arab Medical University at Benghazi during its golden period from 1980 to 1990. During that period the university had eminent teachers of great caliber from India, United States of America and the United Kingdom. Around 150 to 200 students were admitted to the course. The medium of instruction was English. The student attendance was compulsory for the practical as well as lecture classes. There were no private centres of instruction. The students were very interested in their education and had shown great interest in learning. Under the tutelage of eminent teachers the students completed their medical training and proudly occupy great positions in leading hospitals and teaching institutions in Libya and all around the globe. It is a proud moment for any teacher to cherish and witness such great achievements accomplished by the students whom he/she has taught. However, it gives me no pleasure to see the standard of the medical education in Libya slipping despite the massive expansion in the number of medical schools resulting in putting enormous pressure on the scarce resources. At present, Libya has 25000 students in nine medical schools [1], compared to just 9000 practicing doctors, and a total population of around 6 million [2]. \u0000 \u0000In this article I would like to propose some practical measures that may help in reviving medical education in Libya.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124758767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the Oil and Mucilage from Flaxseed (Linum Usitatissimum) on Gastric Lesions Induced by Ethanol in Rats","authors":"A. Dugani, A. Auzzi, F. Naas, S. Megwez","doi":"10.3402/ljm.v3i4.4787","DOIUrl":"https://doi.org/10.3402/ljm.v3i4.4787","url":null,"abstract":"The anti-ulcer activity of the oil and mucilage obtained from flaxseed (Linum usitatissimum) was evaluated in a rat model of ethanol-induced gastric ulcer. Our results show that pretreatment of rats with flaxseed oil and flaxseed mucilage significantly reduced the number and length of gastric ulcers induced by ethanol. Flaxseed oil was more effective than flaxseed mucilage in reducing the number of ulcers. The reduction in ulcer severity (cumulative length in mm) provided by an oral dose of flaxseed oil (5 ml/kg) was more prominent than that obtained by ranitidine (50 mg/kg). This study indicates that both flaxseed oil and flaxseed mucilage can provide a cytoprotective effect against ethanol-induced gastric ulcers in rats.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127260885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Orbital Lymphangioma in a 20-Years Old Girl A Case Report and Review of Literature","authors":"A. Mishra, R. Abuhajar, K. Alsawidi, M. AlAoud, E. Ehtuish","doi":"10.3402/ljm.v4i4.4843","DOIUrl":"https://doi.org/10.3402/ljm.v4i4.4843","url":null,"abstract":"We report a case of a 20-year-old girl who presented to the out-patients’ department with congenital, progressive unilateral proptosis and reduced vision. Ultrasound, computed tomography (CT) scan and magnetic resonance imaging (MRI) were performed. Diagnosis of orbital lymphangioma was made on imaging. Authors highlight the crucial role of imaging in diagnosis and to plan therapeutic approach. This case is reported because of its extreme rarity and unusual presentation.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129624969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antithrombotic Therapy in Patients with Prosthetic Heart Valves","authors":"H. Mohamed","doi":"10.3402/ljm.v4i1.4809","DOIUrl":"https://doi.org/10.3402/ljm.v4i1.4809","url":null,"abstract":"Patients with mechanical valve prostheses require a lifelong anticoagulant treatment. The combined use of Warfarin and low-dose aspirin appears to reduce the risk of valve thrombosis and systemic embolism at a low risk of bleeding. The management of women with prosthetic heart valves during pregnancy poses a particular challenge, as there are no available controlled clinical trials to provide guidelines for effective antithrombotic therapy. Oral anticoagulants, such as Warfarin, cause foetal embryopathy; unfractionated heparin and low-molecular-weight heparin have been reported to be ineffective in preventing thromboembolic complications. This article discusses the available data and the most recent guidelines in the antithrombotic management of patients with prosthetic valves, and antithrombotic therapy in various clinical situations such as pregnant women with prosthetic heart valves, and patients with prosthetic heart valves undergoing noncardiac surgery.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127279147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Significance of neo-angiogenesis and immuno-surveillance cells in squamous cell carcinoma of the tongue","authors":"J. Alkhabuli","doi":"10.3402/ljm.v2i1.4689","DOIUrl":"https://doi.org/10.3402/ljm.v2i1.4689","url":null,"abstract":"Background: Neo-angiogenesis is an essential process in physiological and pathological conditions. However, it is a complex process. Several studies demonstrated that intra-tumoural microvessel number is a significant predictor of metastasis and clinical outcome in many tumours, including oral malignancies. The immuno-surveillance cells, mast cells and eosinophils are implicated in the biological behaviour of tumours. Nevertheless, their function in tissues is uncertain. Mast cells are involved in homeostatic regulation of blood vessels as well as host defence. In some malignancies, high mast cell density has been found to correlate with favourable prognosis. However, others reported unfavourable associations. Tumour associated tissue eosinophilia is a well-known phenomena. It has been associated with good and poor prognosis. However, the role of eosinophils in tumours remains controversial. Therefore, this study was designed to investigate the prognostic value of microvessel, mast cell and eosinophil densities in the context of clinico-pathological parameters and survival in squamous cell carcinoma of the tongue. Materials and Methods: Anti-CD105 and anti-tryptase monoclonal antibodies were utilized to highlight and count microvessels and mast cells respectively in 81 cases of tongue squamous cell carcinoma. Eosinophils were demonstrated using carbol chromotrope histochemical stain. The densities were counted per mm2 and correlated with patients’ outcome and other clinico-pathological parameters using non-parametric tests and student’s t-test. Clinically, the cases were divided into 4 main groups depending on survival time, lymph-node or distant metastasis. Results: The 5 year survival was significantly lower in patients with a low mast cell density than those with a high density (p=0.006, Kruskal-Wallis test). The survival group-A demonstrated significantly higher mast cell and microvessel numbers than group-D (p=0.007, student’s t-test) respectively. Patients with well-differentiated squamous cell carcinoma had significantly higher numbers of mast cells when compared to patients with poorly differentiated squamous cell carcinoma (p<0.05, student’s t-test). The lymph node involvement correlation between the survival group-A and survival group-D was also significant (p=0.001, Mann-Whitney U test). Conclusion: Data from this study indicates that accumulating mast cells in tumours play a part in inhibiting tumour progression and is potentially angiogenic in tumours.","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129366068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can prolonged pregnancy complicate hypothyroidism?","authors":"R. Elmehdawi, Ebtehal Lashika","doi":"10.3402/ljm.v2i4.4725","DOIUrl":"https://doi.org/10.3402/ljm.v2i4.4725","url":null,"abstract":"To The Editor: Women with primary hypothyroidism may have either oligo-, or amenorrhea, or menorrhagia. These menstrual changes often result in decreased fertility. If pregnancy does occur there is an increased likelihood for early abortion or premature labor [1]. Post term pregnancies (PP) have not been reported before. However, it has been hypothesized that prolonged pregnancy is a possible complication of hypothyroidism due to some sort of myometriopathy [2].","PeriodicalId":256060,"journal":{"name":"The Libyan Journal of Medicine","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129397546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}