Bangladesh Heart Journal最新文献

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Association of Platelet Count and Mean Platelet Volume in Acute ST- Elevated Myocardial Infarction 急性 ST 段抬高型心肌梗死患者的血小板计数与平均血小板体积的关系
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70277
Md Shakur Ahmed, M. Uddin, Ummey Zahira Popy, Mohammad Mohammad Ali, Bishnu Pada Saha, Fahdia Afroz, M. Haque, Zahidul Islam Khan, Md Saiful Islam, Monwarul Haque Tohin, Nur Alam, Tariq Ahmed Choudhury, Md Wareshuzzaman, Iftekhar Alam
{"title":"Association of Platelet Count and Mean Platelet Volume in Acute ST- Elevated Myocardial Infarction","authors":"Md Shakur Ahmed, M. Uddin, Ummey Zahira Popy, Mohammad Mohammad Ali, Bishnu Pada Saha, Fahdia Afroz, M. Haque, Zahidul Islam Khan, Md Saiful Islam, Monwarul Haque Tohin, Nur Alam, Tariq Ahmed Choudhury, Md Wareshuzzaman, Iftekhar Alam","doi":"10.3329/bhj.v38i2.70277","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70277","url":null,"abstract":"Background: Early prediction and quick diagnosis with simple, quick and easily available tool is essential part of early management of acute coronary syndrome e.g.  ST segment elevated myocardial infarction. As platelet has a significant role in thrombus formation and larger sized platelets are more active in thrombotic pathogenicity, as such platelet indices can be the early predictor for acute coronary syndrome. \u0000Objective: Aim of this study was to assess the association of platelet count and mean platelet volume (MPV) in acute ST-elevated myocardial infarction.\u0000Methodology: This observational study was conducted at the department of Cardiology of National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh from November 2019 to October 2020. Total 166 subjects were enrolled in this study. Among them 82 subjects (Group I) had acute ST-elevated myocardial infarction on resting ECG were admitted at CCU of NICVD and without any prior history of anti-platelet drugs intake, another 84 subjects (Group II) were enrolled in this study as control group with normal 12 lead resting ECG with normal Troponin-I.\u0000Results: No significant age difference observed between two groups (p =0.063). Significantly higher smoking and family history of coronary artery disease observed with ST elevated MI subjects (p:0.002 and <0.001 respectively). Associated risk factors like hypertension, diabetes and dyslipidemia were significantly high (<0.001) in ST-elevated MI patients. No significant difference observed in platelet count between ST elevated MI groups compared with the control (258 X 109/L vs. 267 X109/L).  Mean platelet volume (MPV) was found to be higher in group I patients as compared to control (12.20±0.86 vs. 9.26±0.77) and it was significant (p <0.001).\u0000Conclusion: In acute ST-elevated myocardial infraction, higher mean platelet volume (MPV) and lower platelet count may be a useful marker.\u0000Bangladesh Heart Journal 2023; 38(2): 120-126","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"35 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Established and Emerging Biomarker in Chronic Heart Failure 慢性心力衰竭的成熟和新兴生物标记物
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70276
Sami Nazrul Islam, Sayeedur Rahman Khan, Md Anwar Hossain, Mohammad Khurshadul Alam, Amanat Hasan, Bivash Kumer Sheel, Tanvir Adnan, Tanha Waheed Brishti, Sharmin Tahmina Khan
{"title":"Established and Emerging Biomarker in Chronic Heart Failure","authors":"Sami Nazrul Islam, Sayeedur Rahman Khan, Md Anwar Hossain, Mohammad Khurshadul Alam, Amanat Hasan, Bivash Kumer Sheel, Tanvir Adnan, Tanha Waheed Brishti, Sharmin Tahmina Khan","doi":"10.3329/bhj.v38i2.70276","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70276","url":null,"abstract":"Background: More than one million hospital admissions each year are due to heart failure as the major diagnosis. One in six patients over 65 who visit a primary care facility complaining of dyspnea with exertion has undiagnosed HF. By far, the most thoroughly investigated, extensively used, and acknowledged biomarkers for heart failure are natriuretic peptides. B type natriuretic peptide (BNP) and its biologically inactive fragment N-terminal pro B-type natriuretic peptide (NT-ProBNP), which are both primarily released by the ventricles in response to stretching, have been suggested to be useful for determining the prognosis or disease severity of chronic heart failure in earlier studies. Uric acid levels rise in CHF primarily due to increased production and occasionally due to decreased excretion or both. Elevated uric acid levels are a sign of developing heart failure and cardiac dysfunction. Numerous studies have demonstrated a connection between morbidity and death in CHF and elevated serum uric acid levels2.\u0000Objective: To find out the relationship between on admission serum uric acid level with established prognostic factors and Biomarkers such as different classes of NYHA, LVEF, NT-PROBNP, and their prognostic significance.\u0000Methods: From April 2018 to March 2019, this study was carried out at the National Heart Foundation Hospital and Research Institute's Department of Cardiology. After considering the inclusion and exclusion criteria, 148 patients with chronic heart failure who had admission serum uric acid measurement and telephone follow-up within 30 days were included. The study patients were divided into two groups based on Serum uric acid level Group I (SUA in men<7mg/dl) (SUA in women <6mg/dl), Group II (SUA in men ≥7mg/dl), (SUA in women ≥6mg/dl) Baseline characteristics, left ventricular ejection fraction (LVEF) were then compared between the two groups.\u0000Results: On 148 patients, the level of serum uric acid was assessed, and follow-up was done, patients with chronic heart failure were shown to have significantly higher levels of hyperuricemia, and there was a strong association between the severity of the rise in serum uric acid (SUA) and the severity of the heart failure. Elevated blood uric acid levels and ejection fraction have an antagonistic relationship. The severity of heart failure can be predicted by hyperuricemia, as evidenced by the association between patients with elevated blood UA levels and a worse New York Heart Association (NYHA) functional class. Higher uric acid levels in patients were linked to negative outcomes and a poor prognosis.\u0000Conclusion: As with NT Pro BNP or other well-established prognostic indicators, lower uric acid levels upon admission can be utilized to predict the prognosis of CHF patients.\u0000Bangladesh Heart Journal 2023; 38(2): 135-142","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"23 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139006782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Determination of Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) In Bangladeshi Adult Patient With or Without LV Dysfunction 确定有或无左心室功能障碍的孟加拉国成年患者的三尖瓣环平面收缩期偏移(TAPSE)值
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70280
R. J. Tamanna, S. J. Hoque, F. M. Pasha
{"title":"Determination of Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) In Bangladeshi Adult Patient With or Without LV Dysfunction","authors":"R. J. Tamanna, S. J. Hoque, F. M. Pasha","doi":"10.3329/bhj.v38i2.70280","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70280","url":null,"abstract":"Background: Tricuspid annular plane systolic excursion (TAPSE) is an Echocardiographic measure that allows us to assess right ventricular systolic function and  it correlates well with reference techniques like Cardiac Magnetic Resonance  Imaging. TAPSE measurement is common in adults.\u0000Objective: Our objective was to determine values of TAPSE in Bangladeshi adults with or without LV systolic dysfunction and to determine the relationship of these values with age, sex, RVIDd, LVEF & EPSS.\u0000Method: This was an   prospective observational study in patients undergoing comprehensive transthoracic echocardiography for any indication. From April  2022  to  April  2023 we prospectively enrolled 100 adult  (from 30 to age 80 years) of both sexes who presented to the Cardiology Clinic of  LABAID Cardiac  Hospital. We performed a complete transthoracic echocardiography  study. We measured TAPSE in 2-dimensional M-mode echocardiograms from the apical  4- chamber view, positioning the cursor on the lateral tricuspid annulus near the free RV wall and aligning it as close as possible to the apex of the heart . The mean values were taken by at least 2 measurements for reducing interobserver and intraobserver   variability’s.  Patients with confirmed congenital & valvular heart disease were excluded.\u0000Results: Mean TAPSE values were 19.15±3.87cm irrespective of LVEF, with no significant differences between sexes,  18.45±3.801  in male , 19.94±3.853 in female (P=.056).   TAPSE value was 22.00±1.581 in person with normal LVEF & 16.77±2.455 in person with reduced LVEF ( P<.001) A statistically significant positive correlation of LVEF (r=.813) and significant negative correlation of EPSS (r=-.639) were observed with TAPSE (p<0.001). But no significant correlation of TAPSE was found between age (r=-.185)). ), gender (r=.192) & RVIDd (r= -.063) (p >0.05). Multivariate analysis confirmed these correlations and the interactions between variables (LVEF & EPSS).  Graphs of estimated population-based TAPSE values adjusted by age and LV function are provided.\u0000Conclusion: We determined values of TAPSE in Bangladeshi adult population with or without LV systolic dysfunction and assessed relationship of these values with age, sex, RVIDd, LVEF & EPSS.  The TAPSE measurement was reproducible and associated directly with LV systolic function. These reference values could guide decision making in daily clinical practice.\u0000Bangladesh Heart Journal 2023; 38(2): 92-101","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"24 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139007545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac Resynchronization Therapy in Anomalous Coronary Sinus: A Case Report 冠状动脉窦异常的心脏再同步疗法:病例报告
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70279
Abeeda Tasnim Reza, M. A. Ali, S. Nabi, P. Bala, A. Tushar, Md Shariful Islam, U. H. Ferdaushi, M. Khan, Nighat Islam, Humaira Jannath
{"title":"Cardiac Resynchronization Therapy in Anomalous Coronary Sinus: A Case Report","authors":"Abeeda Tasnim Reza, M. A. Ali, S. Nabi, P. Bala, A. Tushar, Md Shariful Islam, U. H. Ferdaushi, M. Khan, Nighat Islam, Humaira Jannath","doi":"10.3329/bhj.v38i2.70279","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70279","url":null,"abstract":"A 37-year-old man, a known case of Dilated Cardiomyopathy (DCM) with Post PPM (Permanent Pacemaker) status for last 3 years underwent upgrading of PPM to Cardiac Resynchronization Therapy Pacemaker (CRT-P) in a specialized cardiac center. During the implantation procedure, there was anomalous branching of coronary sinus with absence of lateral branch & presence of a highly tortuous posterior branch causing difficulty in lead placement. Finally left ventricular (LV) lead was placed in the tortuous branch using Judkin’s right catheter. Lead position was stable with excellent threshold. The patient has been followed up with improvement of symptoms.\u0000Bangladesh Heart Journal 2023; 38(2): 155-157","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"3 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139009441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Systemic Immune- Inflammation Index and Severity of Coronary Artery Disease in Acute Myocardial Infarction Patients 急性心肌梗死患者全身免疫炎症指数与冠状动脉疾病严重程度的关系
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70263
Tania Easmin, Md Khalequzzaman, Md Mohsin Ahmed, M. Hasan
{"title":"Association Between Systemic Immune- Inflammation Index and Severity of Coronary Artery Disease in Acute Myocardial Infarction Patients","authors":"Tania Easmin, Md Khalequzzaman, Md Mohsin Ahmed, M. Hasan","doi":"10.3329/bhj.v38i2.70263","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70263","url":null,"abstract":"Background:  Acute myocardial infarction is one of the leading causes of death across the world. Determination of severity is important in patients with acute myocardial infraction for the therapeutic decision making. Systemic immune-inflammation index (SII) has been proposed as a new prognostic marker in patients with acute MI. Several international studies have found to compare the relation between SII and severity of coronary artery disease. In these studies, they demonstrated that the SII is higher in severe CAD. In our country, no such study has been done yet to predict the severity of coronary artery disease by estimating SII in acute MI patients. Moreover, SII is cheap, easily available, non-invasive and routinely done procedure.\u0000Objectives: This study was conducted to find out the association of SII to severity of CAD in acute MI patients.\u0000Methods: This observational cross sectional analytical study was carried out in the Department of Cardiology, Dhaka Medical College Hospital, SSMC and Mitford Hospital and NICVD, Dhaka from March 2021 to February 2022. Patients with acute MI (STEMI and NSTEMI) were approached for this study according to inclusion and exclusion criteria. Coronary angiogram was done during index hospitalization. The severity of coronary artery disease was assessed by Vessel score and Gensini score. According to Gensini score CAD severity detected as mild to moderate (≤50) , severe (>50). Patients were divided into two groups according to Gensini score: Group A, severe CAD ( Gensini score >50) and Group B, mild to moderate CAD( Gensini score ≤50). SII calculated from admission CBC report.\u0000Results: Among 70 patients in our study 33 (47.1%) were in the high Gensini group (Group A) and 37 (52.85%) were in low Gensini group (Group B). Mean systemic immune inflammation index was found significantly higher in group A than group B, p value 0.001. We found strong positive correlation between SII and Gensini score (r= 0.7, p= 0.001). With the increase of SII, Gensini score increases demonstrating more severe CAD. In multivariate logistic regression analysis, after adjustment of confounding, hypertension (p=0.01, OR=4.84), NLR (P=0.004, OR=1.81) and SII (P=0.011. OR=1.002) remain independent predictor of severe CAD. In ROC curve analysis, the AUC of SII for predicting severity of CAD is 0.8 with p value < 0.001, 95% CI (0.71-0.91) and SII cut off value 686 can predict severe CAD with 78% sensitivity and 76% specificity. So, from this study, it is evident that SII is directly associated with coronary artery disease severity.\u0000Conclusion: Increased SII was associated with angiographically severe coronary artery disease in acute Myocardial Infarction patients and this association is independent of conventional cardiovascular risk factors.\u0000Bangladesh Heart Journal 2023; 38(2): 102-109","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"30 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139009477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case of Chronic Thromboembolic Pulmonary Hypertension in association with Deep Vein Thrombosis and Pulmonary Embolism: A case report of a young female in Bangladesh 一例伴有深静脉血栓和肺栓塞的慢性血栓栓塞性肺动脉高压:孟加拉国一名年轻女性的病例报告
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70266
Saurav Das, Uday Shankar Roy Roy, Umme Maimuna, Swarna Paul, A. Awal, Asish Dey
{"title":"A case of Chronic Thromboembolic Pulmonary Hypertension in association with Deep Vein Thrombosis and Pulmonary Embolism: A case report of a young female in Bangladesh","authors":"Saurav Das, Uday Shankar Roy Roy, Umme Maimuna, Swarna Paul, A. Awal, Asish Dey","doi":"10.3329/bhj.v38i2.70266","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70266","url":null,"abstract":"Chronic thromboembolic pulmonary hypertension (CTEPH) is classified as Group 4 Pulmonary Hypertension (PH) in current categorization by WHO. The initial suspicion with clinical presentation, then screening with imaging and confirmation with Right heart catheterization (RHC) are the steps of diagnostic algorithm for CTEPH. We report the case of a 35 years old female presented with progressive swelling of left lower limb for 2 months and shortness of breath for 1 and half months. Examination revealed respiratory rate 28 breaths/min, pitting edema of left leg, left parasternal heave and palpable P2. Doppler study of both lower limbs and Computed tomography pulmonary angiography (CTPA ) confirmed the diagnosis of deep vein thrombosis of left leg (DVT) and pulmonary embolism (PE), respectively. The echocardiography suggested presence of pulmonary hypertension. We approached the patient with conservative management and discharged her home, once she improved, with advice of life-long anticoagulation.\u0000Bangladesh Heart Journal 2023; 38(2): 143-147","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"60 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139009595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulmonary Embolism Successfully Treated with Tenecteplase: A case report 特奈普酶成功治疗肺栓塞:病例报告
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70278
Masuma Jannat Shafi, S. Nasrin, M. M. Haq, Md. Rezaul Karim, K. F. Siraj, R. T. Naab
{"title":"Pulmonary Embolism Successfully Treated with Tenecteplase: A case report","authors":"Masuma Jannat Shafi, S. Nasrin, M. M. Haq, Md. Rezaul Karim, K. F. Siraj, R. T. Naab","doi":"10.3329/bhj.v38i2.70278","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70278","url":null,"abstract":"Acute pulmonary embolism is a life-threatening situation when presenting with hypotension is called high-risk (massive) pulmonary embolism (PE) which is associated with mortality, especially if there is hemodynamic instability, right ventricular dysfunction with thrombus. Thrombolytic therapy can be lifesaving and leads faster improvement in hemodynamics in patients with acute pulmonary embolism and cardiogenic shock which accelerates the resolution of thrombus, reduction of RV dilatation, mortality and recurrent PE. Only three fibrinolytic agents namely Recombinant tissue-type plasminogen activator (rtPA), Streptokinase and Urokinase have been approved in the treatment of PE. We report the case of a 64 years old Bangladeshi female with a history of immobilization due to unilateral cut injury of foot, who presented with shortness of breath and intermittent chest pain for a duration of 7 days during OPD visit. ECG showed sinus tachycardia (HR-120bpm, regular) and poor progression of R wave. Echocardiography revealed dilated RV, PA with RV dysfunction, presence of McConnell’s sign, RV apical & PA thrombus, flattened IVS, PHT, and minimal pericardial effusion, normal LV systolic function which was reported as suspected pulmonary embolism. Urgent hospitalization and CT pulmonary angiogram (CTPA) was done for confirmatory diagnosis which revealed large pulmonary thrombus in both right and left pulmonary artery. Thrombolysis with Tenecteplase (100ml) over 2 hours was started immediately along with intravenous normal saline and norepinephrine for hypotension, although, it was not recommended by the European Society of Cardiology (ESC) guideline, resulting a successful resolution of the PA thrombus and clinical improvement. She was discharged with oral anticoagulant Rivaroxaban. \u0000Bangladesh Heart Journal 2023; 38(2): 148-154","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"24 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139007542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of COVID-19 Infection Among Vaccinated and Unvaccinated Patients in Bangladesh During Second Wave: Single Centre Study 孟加拉国第二波接种疫苗和未接种疫苗患者的 COVID-19 感染情况比较:单中心研究
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70283
Fazila-tun-nesa Malik, Muhammad Kalimuddin, M. Ishraquzzaman, Ashok Dutta, Md Habibur Rahman, Smita Kanungo, N. Laila, Md. Shamim Chowdhury, S. Choudhury, M. Al Mamun
{"title":"Comparison of COVID-19 Infection Among Vaccinated and Unvaccinated Patients in Bangladesh During Second Wave: Single Centre Study","authors":"Fazila-tun-nesa Malik, Muhammad Kalimuddin, M. Ishraquzzaman, Ashok Dutta, Md Habibur Rahman, Smita Kanungo, N. Laila, Md. Shamim Chowdhury, S. Choudhury, M. Al Mamun","doi":"10.3329/bhj.v38i2.70283","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70283","url":null,"abstract":"Background: Vaccination may positively influence the clinical outcome of corona virus disease-19 (COVID-19) patients. But there is a lack of data regarding efficacy of vaccine against COVID-19 infection. This study aimed to compare the baseline characteristics, clinical profiles, and outcomes of COVID-19 infection in vaccinated and non-vaccinated patients in Bangladesh in the second wave.\u0000Methods: This single centre prospective observational cohort study was carried out at National Heart Foundation Hospital & Research Institute from 27th February 2021 to 25th September, 2021 during the second wave. All COVID-positive patients & cardiac patients who became COVID-19 positive during the period of admission were included in this study for comparison.\u0000Results: A total of 858 patients were included. Most patients in the second were unvaccinated (n= 691, 80.5%), while of the 167 individuals who were vaccinated, 125 (14.6%) patients were partially vaccinated while 42 (4.9%) were fully vaccinated. The mean age of the unvaccinated patients was 52.63±16.4 years, partially vaccinated patients was 39.74±14.88 years, and fully vaccinated patients was 50.55 ± 12.48 years (p=0.001). Male were predominant in all groups. In the unvaccinated (98.4% vs 1.6%; p=0.001) and fully vaccinated (81% vs 19%; p=0.001) groups non healthcare personnel (non-HCP) were most commonly affected. Most of the patients (48.7%) in unvaccinated group had ≥4 co-morbidities, while in partially- (51.2%) and fully vaccinated (54.7%) groups most of the patients had <4 co-morbidities (p=0.001). In unvaccinated group asymptomatic & severe disease (11.4% vs 7.2% vs 2.4%; p=0.001) were more prevalent than partially- and fully vaccinated group (table 3). Mortality rate was significantly higher in unvaccinated group than partially vaccinated group (6.2% vs 0.8%; p=0.001). There was no death in fully vaccinated group.\u0000Conclusion:Unvaccinated individuals were more prone to COVID-19 infection. Most of the patients in unvaccinated group had ≥4 co-morbidities. In unvaccinated group asymptomatic & severe disease were more prevalent than partially- and fully vaccinated group. Mortality rate was high in unvaccinated group.\u0000Bangladesh Heart Journal 2023; 38(2): 127-134","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"42 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139007777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasound Based Flow Measurements of the Left and Right Carotid System of Arteries in Bangladeshi Patients 孟加拉国患者左右颈动脉系统的超声流量测量
Bangladesh Heart Journal Pub Date : 2023-12-12 DOI: 10.3329/bhj.v38i2.70281
Abdullah Al Mamun, N. Hosain, Farzana Amin
{"title":"Ultrasound Based Flow Measurements of the Left and Right Carotid System of Arteries in Bangladeshi Patients","authors":"Abdullah Al Mamun, N. Hosain, Farzana Amin","doi":"10.3329/bhj.v38i2.70281","DOIUrl":"https://doi.org/10.3329/bhj.v38i2.70281","url":null,"abstract":"Carotid arteries are the major supply to the head, neck and brain.  The right common carotid artery usually originates from the brachiocephalic artery while the left common carotid artery arises as a direct branch of the arch of the aorta. Common carotid arteries bifurcate at the level of the carotid sinus into the internal carotid artery, which supplies the brain, and the external carotid artery. Approximately 15–20% of the cardiac output is distributed to the brain in healthy adults under resting conditions. Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. US 2017 statistics shows that cerebrovascular disease or Stroke alone ranked fifth for males but fourth for females. Ultrasonography can measure the velocity of blood flow in the Carotid system of arteries. A total 139 patients, who underwent Carotid Duplex study between July 2021 and June 2022 were included in this cross-sectional study. The criteria for exclusion included age less than 13 years, presence of associated peripheral vascular diseases, hemodynamically unstable patients, incomplete data collection and patient’s reluctance to join the study. Data analysis was performed using MS Office Excel. The Peak systolic velocity and the End diastolic velocity were measured at four levels, namely the Common carotid arteries and the Internal carotid arteries on the right and the left sides. No significant difference was observed in the Peak systolic velocity and the End diastolic velocity in either Common carotid or the internal carotid arteries between the right and left sides. Moreover, these findings were similar both in age groups above and below 50 years of age.\u0000Bangladesh Heart Journal 2023; 38(2): 110-114","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"37 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139008449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
First Ever Hybrid Procedure of Balloon Co-arctoplasty & Patent Ductus Arteriosus (PDA) Ligation in a Neonate in Bangladesh 在孟加拉国,首次在新生儿中应用球囊辅助结肠成形术和动脉导管未闭结扎术
Bangladesh Heart Journal Pub Date : 2023-07-08 DOI: 10.3329/bhj.v38i1.67223
N. Fatema, M. Shaukat, Ashik Md Raihan Chowdhury
{"title":"First Ever Hybrid Procedure of Balloon Co-arctoplasty & Patent Ductus Arteriosus (PDA) Ligation in a Neonate in Bangladesh","authors":"N. Fatema, M. Shaukat, Ashik Md Raihan Chowdhury","doi":"10.3329/bhj.v38i1.67223","DOIUrl":"https://doi.org/10.3329/bhj.v38i1.67223","url":null,"abstract":"Coarctation of the aorta is a rare form of congenital heart disease, though preductal co-arctation is not very uncommon. This is a report on a 28-day-old girl who was referred to our center for evaluation. Doppler echocardiography showed severe preductal coarctation of aorta and a small-sized Patent Ductus Arteriosus (PDA). Later, it was confirmed by aortogram which showed critical coarctation of aorta (COA) with a very large Patent Ductus Arteosus (PDA). This full-term infant with symptomatic COA and a large PDA was treated successfully with a hybrid procedure of Balloon angioplasty and PDA ligation. \u0000Bangladesh Heart Journal 2023; 38(1): 88-91 ","PeriodicalId":247590,"journal":{"name":"Bangladesh Heart Journal","volume":"27 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125997501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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