Medical Science Journal for Advance Research最新文献

{"title":"Frequency Of Magnetic Resonance Imaging Findings In Patients With Lower Back Pain","authors":"K. Wara, T. Zulfiqar","doi":"10.46966/msjar.v4i1.105","DOIUrl":"https://doi.org/10.46966/msjar.v4i1.105","url":null,"abstract":"Aims and objectives: To assess the MRI findings in patients who had lower back pain. Lower back pain affects most of the adults at some time in their lives. Background: The most common anomaly is lumbar disc degeneration, which can be caused by degenerative disc changes, narrowing of spaces in lumber spinal, cancer, infection, or trauma. In the evaluation of patients with lower back pain, Magnetic Resonance Imaging (MRI) has been the best modality to determine because this one is radiation free, non-invasive imaging modality with great both resolution (spatial and contrast).[1] Goal of this research was to find out the findings on MRI in patients who had lower back pain. Methods:  This Descriptive cross-sectional study a total of 63 patients was conducted at the Radiology Department of Punjab Diagnostic Centre, Gujranwala, who had a lumbar spine MRI for severe and persistent lower back pain, radiculopathy, claudication (neurogenic) , or other symptoms and indications that could indicate low back discomfort. The age range of patients was 16 to 68 years. Non-contrast MRI scans was done. SPSS was used for statistical analysis. Magnetic Resonance Imaging (MRI) scan findings for patients who had lower back pain were determined. \u0000Results: Out of 63 patients there were (57.1%) 36 male patients and (42.9%) 27 female patients participated in this study. In Lumber spine straightening out of 63 patients in which there 23 patients (63.5%) noted (10) female and (13) male respectively. In 40 cases, the most well-known category was disc bulging at the L4/L5 level (63.4 percent) and L5/S1level was noted in 31 cases (49.1%) followed by L3-L4 level was noted in 11 cases (17.5%) in order of decreasing frequency. And Disc herniation was seen at total 16 patients (25.4percent) respectively. Disc herniation was more common at L4/L5 level. Disc desiccation was the most well-known category at L5/S1 in 35 cases (55.6%), L4/L5 level was noted in 24 cases (38.1%), L3/L4 level was noted in 14 cases (22.2%) and L2/L3 was noted in 7cases (11.1%) in order of decreasing frequency. Indentation of anterior theca was observed in 41.3% (26) of the total cases. In 76.2% (48) patients compression of the nerve root was seen out of total cases. Stenosis of the spinal canal was seen in 38.1% (24) out of the total cases.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"195 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120913151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency Of Splenomegaly In Patients With Abdominal Ultrasound","authors":"Sumbal Saleem","doi":"10.46966/msjar.v3i4.93","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.93","url":null,"abstract":"Aims and objectives:  To find out the frequency of splenomegaly in patients with abdominal ultrasound  Methods: This prospective cross-sectional study was conducted at the Radiology Department of City Care Hospital in Gujranwala. A total of 65 participants with pain in the left upper quadrant were included in the study. Patients ranged in age from 21 to 75 years old, with 37 men and 28 females. Statistical analysis was then performed using SPSS. In individuals with left upper quadrant pain, the frequency of splenomegaly is calculated. Results: Out of 65 patients who presented with splenomegaly, positive cases for splenomegaly reported were 26 and negative cases were 39 \u0000Conclusion:  For detecting splenomegaly, sonography is a good modality with numerous advantages. It is nonionizing radiation free, relatively inexpensive, widely available, and simple to use, with a high diagnostic effectiveness. Patients who have complained of abdominal pain have been concluded. \u0000 ","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122440093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasound Frequency Of KUB Stones In Patients With Flank Pain","authors":"Amen Asif","doi":"10.46966/msjar.v3i4.94","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.94","url":null,"abstract":"Aims and objectives: To find out the frequency of kUB stones in patients with flank pain.  Methods: This prospective cross-sectional study was done at the Radiology Department of DHQ Hospital, Gujrat. It includes a total 61 patients who presented with flank pain. The age range of patients was between 21 to 75 years and included 35 males and 26 females.  SPSS was then used for Statistical analysis. Frequency of renal tract stones was calculated.  Results: - Out of 61 patients who presented with flank pain, stones were present in 45 (73.7%) patients. 17( 27.9%) stones  were   seen in right kidney, 12(19.7%) stones were seen in left kidney,13(21.3%) in right ureter and 3(4.91%) in left ureter. \u0000Conclusion: -  Sonography is an excellent modality with many benefits for diagnosing kidney stones it is  non-ionizing radiation free, relatively inexpensive,   widely available, and simple to use, with a high diagnostic effectiveness. It is concluded patients that are reported with flank pain have kidney stones.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116729150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modeling Of Beta-Lactamase Protein In Klebsiella Pneumoniae: In Silico Study","authors":"Noor Naser Raheem","doi":"10.46966/msjar.v3i4.80","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.80","url":null,"abstract":"Background: Klebsiella pneumoniae is a bacterium that normally lives inside human intestines, where it doesn't cause disease. But if K. pneumoniae gets into other areas of the body, it can lead to a range of illnesses, including pneumonia, bloodstream infections, meningitis, and urinary tract infections. The results that have been obtained from some servers that have been used in this study were gave a poor and good quality of prediction. SWISS MODEL server gave more promising results. Validation was done for the model study by using QMEAN score and ProSA server. 3D Refine and Mod Refiner were used for model refinement. Finally, ProSA server have been used in order to revalidate themodel.                                   .Conclusion: SwissMODEL is a three-dimensional structure of an assumed protein sequence that was predicted via homology modeling, and this three-dimensional structure is based mostly on alignments to one or more proteins with known structures. Following construction of the model, it was evaluated and enhanced using 3D-Structure modeling software, which was developed by the University of California, San Francisco (UCSF).","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"86 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126171287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abdominal Myomectomy For The Treatment Of Symptomatic Uterine Fibroids","authors":"T. Malik","doi":"10.46966/msjar.v3i4.95","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.95","url":null,"abstract":"Background: Fibroids are common problem for women in elderly reproductive age. Aim: The present study aimed at assessing abdominal myomectomy for the treatment of symptomatic uterine fibroids. Methodology: The present retrospective study was conducted from 22 June 2020 to 23 July 2021 at Mayo Hospital, Lahore. Females undergone abdominal myomectomy with age 30 to 50 years were included. The primary and secondary outcomes were defined and assessed to evaluate the procedure. Results: The findings indicate that 32 (62.74%) of the patients showed successful outcome for menorrhagia. On the other hand, 27 (50.94%) patients showed successful outcome for pain and 30 (60%) showed for mass effect. \u0000Conclusion: Abdominal myomectomy is an ideally applicable procedure for the removal of fibroids.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115405322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Report Of New Delhi Metallo-Beta-Lactamase (NDM) Producing Citrobacter Braakii Isolated From Diabetic Foot Infection In Iraq","authors":"Huda Zuhair Wahid","doi":"10.46966/msjar.v3i4.86","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.86","url":null,"abstract":"Background: Diabetic foot infection (DFI) is an infection in soft tissue or bone in patient with diabetes mellitus, Citrobacter species are infrequent nosocomial pathogens and cause a range of infections. the aim of the current study we report the isolation of carbapenem genes among Citrobacter species isolated from DFI. Methods: about 111 swabs specimen were collection from patient suspected with DFI during the period of study, determine the antibiotic susceptibility of Citrobacter spp isolates by using Kirby-Bauer disk diffusion method to 23 antimicrobial agents according to the CLSI (2021). Molecular detection for MBL genes by multiplex PCR. Results: from 111 swabs specimen Citrobacter spp isolates had represented in 3 (4.34%) among Gram-negative bacteria. Antibiotic susceptibility test revealed that one isolate of Citrobacter braakii was MDR and the other isolates was PDR. The PCR data of MBL genes revealed that the frequency of MBL genes among Citrobacter braakii  as following blaVIM, blaNDM, and blaSIM  were 100%. Conclusion: the study show the appear MDR and PDR among Citrobacter species and Citrobacter braakii isolate carry  the MBL genes (blaVIM, blaNDM,, and blaSIM) where  the dissemination of NDM producing Citrobacter braakii considered first reported in Iraq.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"142 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127555131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Biofilm And Role In The Pathogenesis Of Disease","authors":"Bent alhuda Hussein Neamah","doi":"10.46966/msjar.v3i4.82","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.82","url":null,"abstract":"Background: Bacterial biofilms may play a role in pathogenesis which has led to increased focus on identifying diseases that may be associated with biofilms. Chronic biofilm infections are usually chronic in nature, as the bacteria that live in biofilms can be resilient to both the immune system and antibiotics and other treatments. Current knowledge of how biofilms contribute to disease pathogenesis suggests a number of different mechanisms. This extends from biofilms being merely a reservoir of pathogenic bacteria, to playing a more active role, for example, by contributing to inflammation. This knowledge is important for developing effective treatment strategies for such infections. \u0000 ","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125064533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MRI Findings In Patients With Headache And Vertigo","authors":"T. Malik","doi":"10.46966/msjar.v3i4.96","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.96","url":null,"abstract":"BACKGROUND:A headache is a condition of pain in the head. In Medical nomenclature, it is known as cephalgia.Primary and secondary headaches are the two forms of headaches. The first type of headache is primary headache, which includes migraine, cluster headaches, and tension headaches. They are non-aggressive in nature. Primary headaches are usually chronic in character and are caused by no underlying functional illness. The second type of headache is secondary headache, which is always brought on by major organic disorders. It can range from benign cranial conditions like sinusitis or mastoiditis to life-threatening intracranial pathologies like subarachnoid haemorrhage or brain tumours. Vertigo is a perception of motion or spinning that is often represented as dizziness. Vertigo is not the same as being featherbrained. People with vertigo tone as though they are actually handicraft or moving, or that the world is spinning around them. Vertigo is frequently caused by issues with certain regions of the brain. Vertigo can be caused by a variety of factors, including benign paroxysmal positional vertigo (BPPV), which occurs when certain head motions cause vertigo. Migraines are a type of severe headache. Mostly the  patients with vertigo and headache normally do not require a brain MRI. For Secondary reason of headache,some patients need an brain MRI. MRI is best Diagnostic modality for the diagnosis and management of secondary headache and vertigo. CONCLUSION: Magnetic resonance imaging (MRI) is a finest diagnostic modality that creates detailed images of the organs and tissues in your body using a magnetic field and computer-generated radio waves. It is considered as the best diagnostic method for the diagnosis and therapy of secondary headache and vertigo. A modest percentage of medical institution fundamental positive findings in neuroimaging are seen in MRI of patients with headache. In these patients, the cost-effectiveness of MRI as a screening tool is of limited benefit.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"48 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124084165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Computed Tomography Imaging Of Traumatic Brain Injuries In Patients Presented With A History Of Fall","authors":"Esha Nafees","doi":"10.46966/msjar.v3i4.91","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.91","url":null,"abstract":"Aim and objective: The goal of our research was to find traumatic brain injuries in patients who had a history of falling and had a CT scan. Material and methodology: The Radiology Department of DHQ Hospital, Jhelum, conducted this prospective cross-sectional study for 3 months. It includes a total of 79 patients who presented with a history of fall. The patients included 35 males & 26 women, ages ranging from one to ninety-five yrs. The frequency of findings was assessed by using SPSS version 20. Results: Out of 79 patients, 36 cases were found to have brain fractures, 23 participants showed scalp thickness while 17 patients had a hematoma and 12 patients had opacification. \u0000Conclusion: Children made up most of the fall injury patients that visited emergency rooms. Frequent Emergency department visits in youngsters due to fall-related traumatic brain injury indicate a significant public health load, as evidenced by a rise in emergency room visits for TBI caused by a fall in an age category with a significantly greater risk of falling and a larger chance of long-term effects from the injury.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123428295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation Of NLRP3 Inflammasome Activity In Cardiovascular Diseases Patients In Najaf Governorate","authors":"Dhuha Adnan Kadhem","doi":"10.46966/msjar.v3i4.83","DOIUrl":"https://doi.org/10.46966/msjar.v3i4.83","url":null,"abstract":"Background: The NLRP3 inflammasome is a crucial constituent of innate immunity, mediating caspase-1 stimulation and the production of pro-inflammatory cytokines Interleukin one and Interleukin-18. Still, abnormal activating of the NLRP3 inflammasome is being connected to a number of inflammatory diseases, such as diabetes, and atherosclerotic cardiovascular disease. Cardiovascular diseases are still widespread with significant deaths and morbidity ratios. Most CVDs are caused by vascular damage, including atherosclerosis, aneurysms, and subsequent ischemic heart conditions.   Aim of the study: Evaluation of NLRP3 inflammasome activity in cardiovascular diseases.Methodology: This study (cross-sectional study) included 200 individuals with cardiovascular disorders from January 2022 and May . The patients ranged in age from (1 to 80) years old, with 58 females and 142 males among the 200 cases. The serum samples of patients were obtained for screening of the presence of   NLRP3 Inflammasome by ELISA using commercial kits (SUNLONG_CHINA).Results: Patients with cardiovascular disease were divided into 4 aging groups as, the following: The 1st  age group (<20) yrs. old, The 2nd age group (20-39) yrs. old, The 3rd age group (40-59) yrs. old, and the last group,  is(60-79). The results clearly showed that a high percentage of ischemic heart disease was present among all age groups compared to others types followed by structural heart disease. The current study's cardiovascular patients were higher in males compared to females by about 142(71%) vs 58(29%) of all 200 participants. The study indicates that significant results for NLRP3  inflammasome were present among age groups patients with a p-Value equal to 0.03, it also indicates that there are no significant results for NLRP3  inflammasome among sex groups of patients with a p-Value equal to 0.402. And also an association between CVD and study marker showed no significant difference between seropositive NLRP3  inflammasome with cardiovascular disease types. \u0000Conclusions: The most common cardiovascular type in the study was ischemic heart disease. Cardiovascular disease affects men more than women, and it gets worse as people get older.","PeriodicalId":245917,"journal":{"name":"Medical Science Journal for Advance Research","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127828895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}